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Sexual Attitudes among College Students: An Approach in Mexico

Open Journal of Obstetrics and Gynecology 2015年第7期5卷 400-405页

作者： Aurora Montanez-Frausto Aliciaálvarez Aguirre georgina olvera-villanueva Ma.Teresa Hernández Ramos Nereyda Hernández Nava Ma.del Rocio Rocha-Rdz Department of Nursing and Midwifery Health Sciences DivisionCampus LeónUniversity of GuanajuatoGuanajuatoMexico Nursing Department Campus Health Sciences and EngineeringUniversity of GuanajuatoGuanajuatoMexico School of Nursing Autonomous University of QueretaroSantiago de QuerétaroMexico Department of Nursing Academic Coordination Altiplano RegionAutonomous University of San Luis PotosiSan Luis PotosiMexico Department of Nursing Multidisciplinary Academic Unit Central ZoneAutonomous University of San Luis PotosiSan Luis PotosiMexico

Objective: To develop a predictive model for HIV/AIDS in the sexual behavior of university students from a public university in the state of Guanajuato. Methodology: Correlational study involved 294 university students from 18 to 19 years of age by stratified random sampling. The instruments used were: attitudes, subjective norms, self-efficacy and intentions for HIV/AIDS and sexual behavior. Descriptive statistics, normality test of Kolmogorov-Smirnov test, Spearman correlation and logistic regression was used. Results: In describing sexual behavior of young students at the beginning of sexual life is observed that 61.9% of them have had sexual life, with higher per- centage in men. Of the 182 university students who reported first sexual intercourse used a contraceptive method 138 and 135 specifically used a condom the first time they had sex. The variables that have the ability to predict the sex drive at the start of sexual life, are the attitudes and perceived behavioral control (X2 = 39,638, df = 4, p < 0.000), reporting a 12.6% of explained variance. Conclusions: In general, university students today are perceived as vulnerable to sexual behavior and have safe sex, which leads us to think that protect not get HIV/AIDS and unwanted pregnancies.

关键词： HIV/AIDS Youth Sexual Behavior Attitudes Intentions Subjective Norms

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Long-term monitoring reveals the effect of precipitation and silviculture on Nothofagus regeneration in Northern Patagonia mixed forests

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Ecological Processes 2024年第02期13卷 103-117页

作者： georgina Sola Camila Mateo Alejandro Dezzotti Paula Marchelli Hernán Attis Beltrán Renato Sbrancia Luis Chauchard Marcelo González Pe?alba Martín Lara Verónica El Mujtar Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET ) Asentamiento Universitario San Martín de los Andes (AUSMA-UNCo) Instituto de Investigaciones Forestales y Agropecuarias Bariloche (IFAB) Instituto Nacional de Tecnología Agropecuaria (INTA) Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET ) Departamento de Conservación y Manejo Parque Nacional Lanín- Administración de Parques Nacionales (PNL-APN)

Background Tree regeneration is a key component of resilience because it promotes post-disturbance recovery of forests. Northwestern Patagonia from Argentina is occupied by Nothofagus alpina（Na）, N. obliqua（No）, and N. dombeyi（Nd） forests that grow along an intense precipitation gradient, managed throughout shelterwood silvicultural system by technicians of the Lanin Natural Reserve. The objective of this study was to evaluate the influence of seeding cuttings over the dynamics of Nothofagus mixed forests across landscape（precipitation gradient） based mainly on the composition and abundance of tree regeneration, permanent sampling plots and generalized linear mixed models. In particular, we analysed:（i） the structure of sexual and asexual regeneration during 20 years after harvest（the dynamics of managed forests）, and（ii） the structure of sexual regeneration in primary and managed forests after > 20 years of harvest（the effect of silviculture）.Results Nd was the most abundant species in the regeneration of managed forests during all periods in both sites despite its lower contribution to the adult cohort. During the 10–20 years period after harvest, the humid site exhibited higher regeneration density than the mesic site(120,000 and 6000 ind ha-1, respectively), and it decreased afterwards. The number of established regeneration（> 2 m height） was lower for Na in the mesic site and for No in the humid site(0 and 57 ind ha-1, respectively). However, in comparison to No, Na showed a higher number of sprouted stumps and sprouts per stump, and a higher sprout height in the mesic site. No exhibited higher sprout mortality in the humid site. Finally, the regeneration of primary forests showed lower density and height, and a more balanced composition than that of managed *** The silvicultural effects on the mixed forest regeneration dynamics was strongly influenced by the condition of sites. Therefore, management prescriptions should be adj

关键词： Nothofagus alpina Nothofagus obliqua Nothofagus dombeyi Basal sprouting Shelterwood silvicultural system Ecological resilience

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Analysis of Secured Cloud Data Storage Model for Information

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Journal of Software Engineering and Applications 2024年第5期17卷 297-320页

作者： Emmanuel Nwabueze Ekwonwune Udo Chukwuebuka Chigozie Duroha Austin Ekekwe georgina Chekwube Nwankwo Department of Computer Science Imo State University Owerri Nigeria Department of Computer Science Gregory University Abia Nigeria Department of Computer Science Anambra State University Awka Nigeria

This paper was motivated by the existing problems of Cloud Data storage in Imo State University, Nigeria such as outsourced data causing the loss of data and misuse of customer information by unauthorized users or hackers, thereby making customer/client data visible and unprotected. Also, this led to enormous risk of the clients/customers due to defective equipment, bugs, faulty servers, and specious actions. The aim if this paper therefore is to analyze a secure model using Unicode Transformation Format (UTF) base 64 algorithms for storage of data in cloud securely. The methodology used was Object Orientated Hypermedia Analysis and Design Methodology (OOHADM) was adopted. Python was used to develop the security model;the role-based access control (RBAC) and multi-factor authentication (MFA) to enhance security Algorithm were integrated into the Information System developed with HTML 5, JavaScript, Cascading Style Sheet (CSS) version 3 and PHP7. This paper also discussed some of the following concepts;Development of Computing in Cloud, Characteristics of computing, Cloud deployment Model, Cloud Service Models, etc. The results showed that the proposed enhanced security model for information systems of cooperate platform handled multiple authorization and authentication menace, that only one login page will direct all login requests of the different modules to one Single Sign On Server (SSOS). This will in turn redirect users to their requested resources/module when authenticated, leveraging on the Geo-location integration for physical location validation. The emergence of this newly developed system will solve the shortcomings of the existing systems and reduce time and resources incurred while using the existing system.

关键词： Cloud Data Information Model Data Storage Cloud Computing Security System Data Encryption

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Systematic Review: Psychological Changes in Women Diagnosed with Breast Cancer

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Open Journal of Obstetrics and Gynecology 2024年第7期14卷 1096-1109页

作者： Hamilton Dos Prazeres Tavares Augusta Josefina Marques Sachiteque Silvina georgina Tavares Fernando Mango Saiengue Alberto Capoco Sachiteque Cezaltina Nanduva Kahuli Job Monteiro Tavares Daniel Pires Capingana Suelma Beatriz Marques Prata Tavares Department of Gynecology and Obstetrics General Hospital of Huambo Huambo Angola Faculty of Medicine University Jos Eduardo dos Santos Huambo Huambo Angola Department of Gynecology and Obstetrics Hospital Municipal of Huambo Huambo Angola Department of Gynecology and Obstetrics Hospital Municipal of Bailundo Huambo Angola Department of Internal Medicine General Hospital of Huambo Huambo Angola Department of Gynecology and Obstetrics Hospital Municipal of Cala Huambo Angola

Breast cancer is considered one of the most common cancers among women, accounting for 25% - 29% of new cases worldwide each year. The diagnosis, living with the disease, as well as the different treatments can have important impacts on the Psychological and mental health of patients. Objective: To investigate the psychological aspects that women with breast cancer develop or may develop. Methodology: A systematic review using the PRISMA methodology was used. Results: 11 articles that met the inclusion and exclusion criteria were analysed. The largest flow of publications in relation to the effects of the patient with cancer, were carried out between the years 2000 and 2023. Conclusions: Psychological disorders (depression, anxiety, stress) are part of the lives of women diagnosed with breast cancer, and their prevalence varies from one woman to another.

关键词： Anxiety Depression Psychosis Sadness Cancer

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Default polyfunctional T helper 1 response to ample signal 1 alone

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Cellular & Molecular Immunology 2021年第7期18卷 1809-1822页

作者： Luca Danelli georgina Cornish Julia Merkenschlager George Kassiotis Present address:Laboratory of Molecular Immunology The Rockefeller UniversityNew YorkNY10065USA Department of Medicine Faculty of MedicineImperial College LondonLondonW21PGUK Retroviral Immunology The Francis Crick Institute1 Midland RoadLondonNW11ATUK

CD4^(+)T cells integrate well-defined signals from the T-cell receptor(TCR)(signal 1)and a host of costimulatory molecules(signal 2)to initiate clonal expansion and differentiation into diverse functional T helper(Th)***,our ability to guide the expansion of context-appropriate Th subsets by deploying these signals in vaccination remains *** cell-based vaccines,we selectively amplified signal 1 by exclusive presentation of an optimized peptide:MHC II(pMHC II)complex in the absence of classic *** to expectations,amplified signal 1 alone was strongly immunogenic and selectively expanded highaffinity TCR clonotypes,despite delivering intense TCR *** contrast to natural infection or standard vaccines,amplified signal 1,presented by a variety of professional and nonprofessional antigen-presenting cells(APCs),induced exclusively polyfunctional Th1 effector and memory cells,which protected against retroviral infection and tumor challenge,and expanded tumor-reactive CD4^(+)T cells otherwise rendered unresponsive in tumor-bearing ***,our findings uncover a default Th1 response to ample signal 1 and offer a means to selectively prime such protective responses by vaccination.

关键词： CD4 T cell priming T helper differentiation peptide-MHC II complex

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HIF-1α pathway: role, regulation and intervention for cancer therapy

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Acta Pharmaceutica Sinica B 2015年第5期5卷 378-389页

作者： georgina N.Masoud Wei Li Department of Pharmaceutical Sciences College of Pharmacy the University of Tennessee Health Science Center

Hypoxia-inducible factor-1 (HIF-1) has been recognized as an important cancer drug target. Many recent studies have provided convincing evidences of strong correlation between elevated levels of HIF-1 and tumor metastasis, angiogenesis, poor patient prognosis as well as tumor resistance therapy. It was found that hypoxia (low O2 levels) is a common character in many types of solid tumors. As an adaptive response to hypoxic stress, hypoxic tumor cells activate several survival pathways to carry out their essential biological processes in different ways compared with normal cells. Recent advances in cancer biology at the cellular and molecular levels highlighted the HIF-1α pathway as a crucial survival pathway for which novel strategies of cancer therapy could be developed. However, targeting the HIF-1α pathway has been a challenging but promising progresses have been made in the past twenty years. This review summarizes the role and regulation of the HIF-1α in cancer, and recent therapeutic approaches targeting this important pathway.

关键词： HIF-1α HIF-1α inhibitors Cancer drug discovery and development

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New instability and mixing simulations using SPH and a novel mixing measure

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Journal of Hydrodynamics 2020年第4期32卷 684-698页

作者： georgina Reece Benedict D.Rogers Steven Lind Georgios Fourtakas Department of Mechanical Aerospace and Civil EngineeringUniversityof ManchesterManchesterUK

This paper assesses the ability of smoothed particle hydrodynamics (SPH) to simulate mixing of two-phase flows and theirtransition to instabilities under different flow regimes. A new measure for quantification of the degree of mixing between phases in aLagrangian framework is also developed. The method is validated using the lid-driven cavity and two-phase Poiseuille flow cases. Thevelocity along the centre of the cavity is compared with results from the literature, whilst commercial volume-of-fluid codeSTAR-CCM+ provides a benchmark for the mixing and different mixing measures are considered. The velocity of two-phase Poiseuilleflow along the channel is compared to the analytical solution, and the appearance of interfacial instabilities with perturbation *** is the first time SPH has been used to investigate the onset and development of these instabilities. In particular, it is able to modelthe deforming shape of the interface, which is not given by analytical studies, while also offering improved predictions overconventional mesh-based computational fluid dynamics simulations.

关键词： Smoothed particle hydrodynamics(SPH) multi-phase mixing instability

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Transcriptional Regulation and Signaling in Phosphorus Starvation: What About Legumes?

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Journal of Integrative Plant Biology 2008年第10期50卷 1213-1222页

作者： Oswaldo Valds-López georgina Hernndez Centro de Ciencias Genómicas Centre for Genomic Sciences Universidad Nacional Autónoma de Mxico National University of MexicoCuernavaca Morelos 62210 Mxico

The availability of soil phosphorus （P）, an essential element, is one of the most important requirements for plant growth and crop production. The morphological and physiological adaptations evolved by plants to cope with P starvation have been well characterized. Several P deficiency plant responses are regulated at the transcriptional level. Microarray analysis has generated valuable information on global gene expression in Arabidopsis thaliana grown under P-stress. Despite the identification of P responsive genes, little is known about the regulation of gene expression changes. Four transcription factors, PHRI, WRKY75, ZAT6 and BHLH32, involved in P starvation signaling have been characterized in Arabidopsis, and signaling pathways are deciphered. This review analyzes the current knowledge of transcriptional regulation of P starvation responses in Arabidopsis vis-a-vis legumes such as lupine, common bean and Medicago truncatula. The knowledge on regulatory and signaling mechanisms involved in P acquisition and use in legumes will be useful for improvement of these crops, which account for a large proportion of the world＇s crop production, providing good nutritional quality feed and food.

关键词： legumes phosphorus starvation responses P starvation signaling pathways transcriptional regulation transcription factors.

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Bioactive potential of natural biomaterials: identification, retention and assessment of biological properties

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Signal Transduction and Targeted Therapy 2021年第4期6卷 1171-1198页

作者： Kieran Joyce georgina Targa Fabra Yagmur Bozkurt Abhay Pandit School of Medicine National University of IrelandGalwayIreland CURAM SFI Research Centre for Medical DevicesNational University of IrelandGalwayIreland

Biomaterials have had an increasingly important role in recent decades,in biomedical device design and the development of tissue engineering solutions for cell delivery,drug delivery,device integration,tissue replacement,and *** is an increasing trend in tissue engineering to use natural substrates,such as macromolecules native to plants and animals to improve the biocompatibility and biodegradability of delivered *** the same time,these materials have favourable mechanical properties and often considered to be biologically *** importantly,these macromolecules possess innate functions and properties due to their unique chemical composition and structure,which increase their bioactivity and therapeutic potential in a wide range of *** much focus has been on integrating these materials into these devices via a spectrum of cross-linking mechanisms,little attention is drawn to residual bioactivity that is often hampered during isolation,purification,and production ***,we discuss methods of initial material characterisation to determine innate bioactivity,means of material processing including cross-linking,decellularisation,and purification techniques and finally,a biological assessment of retained bioactivity of a final *** review aims to address considerations for biomaterials design from natural polymers,through the optimisation and preservation of bioactive components that maximise the inherent bioactive potency of the substrate to promote tissue regeneration.

关键词： biomaterials linking potential

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Multi-commodity Optimization of Peer-to-peer Energy Trading Resources in Smart Grid

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Journal of Modern Power Systems and Clean Energy 2022年第1期10卷 29-39页

作者： Olamide Jogunola Bamidele Adebisi Kelvin Anoh Augustine Ikpehai Mohammad Hammoudeh georgina Harris Manchester Metropolitan University ManchesterUK Department of Electrical and Electronic Engineering University of BoltonBoltonUK Department of Engineering and Mathematics Sheffield Hallam UniversitySheffieldUK Department of Computing and Mathematics Manchester Metropolitan UniversityManchesterUK School of Science Engineering and EnvironmentUniversity of SalfordSalfordUK

Utility maximization is a major priority of prosumers participating in peer-to-peer energy trading and sharing(P2P-ETS).However,as more distributed energy resources integrate into the distribution network,the impact of the communication link becomes *** present a multi-commodity formulation that allows the dual-optimization of energy and communication resources in *** one hand,the proposed algorithm minimizes the cost of energy generation and communication *** the other hand,it also maximizes the global utility of prosumers with fair resource *** evaluate the algorithm in a variety of realistic conditions including a time-varying communication network with signal delay signal *** results show that the convergence is achieved in a fewer number of time steps than the previously proposed *** is further observed that the entities with a higher willingness to trade the energy acquire more satisfactions than others.

关键词： Distributed algorithm social welfare peer-to-peer energy trading and sharing multi-commodity networks economic dispatch packet loss peer-to-peer energy trading distributed dual-gradient(DDG)

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