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Intensive care unit outcomes in patients with hematological malignancy

Blood Science 2020年第1期2卷 33-37页

作者： Jarrod Leigh Rawson Fionnuala Mary Fagan georgin claire burrough Helen Michelle Tang Moire Alys Cuncannon Katrina Louise Ellem Anoop Kumar Enjeti Hematology Unit Calvary Mater NewcastleNSW NSW Health Pathology North-Hunter Intensive Care Unit Calvary Mater NewcastleNSW University of Newcastle CallaghanNSW Hunter Medical Research Institute New LambtonNSW Hunter Cancer Research Alliance NSW

Hematological malignancies are usually life-limiting *** of care need to be decided early,based on acceptability to the patient,family,physician,and *** intensive care unit(ICU)admission is likely to result in significant physical,psychological,and economic *** is little published on the impact of non-acute preadmission disease factors on ICU outcomes in hematological ***:To identify baseline performance and disease-associated factors before admission to ICU in patients with hematological malignancy that contribute to subsequent ICU ***:A retrospective analysis of electronic medical records,laboratory results,and Intensive Care data for all patients(n=184)with hematological malignancy admitted to the Calvary Mater Hospital ICU between January 1,2013 and June 30,2017 was *** age,gender,condition,Eastern Cooperative Oncology,and Charlson Comorbidity scores were compared to ICU outcome and overall ***-specific prognostic risk scores were compared to ICU ***:Overall,73.9%survived the ICU admission,with 31.6%surviving at 12 *** ejection fractions(>55%)and prognosis>12 months(based on disease-specific risk scores)were significantly associated with overall survival(P=0.024 and P=0.001).Induction and posttransplantation therapy were predictive of poor ICU survival outcome(P<0.0001 and P=0.041).APACHE scores were significant predictors of ICU mortality(P=0.002 for APACHE II and P<0.0001 for APACHE III).Conclusion:Survival outcomes for patients with hematological malignancy admitted to the ICU correlate with functional and comorbidity ***-specific prognostic scores can assist in recognizing patients likely to benefit from ICU admission.

关键词： Comorbidity Hematologic malignancy Intensive care Prognosis

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