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Chemical Quality of Landrace Varieties Cultivated in Traditional Communities in the State of Maranhao, Brazil

Journal of Agricultural Science and Technology(B) 2018年第4期8卷 234-241页

作者： Djanira Rubim dos Santos georgiana eurides de carvalho marques Vivian do Carmo Loch Roberta Almeida Muniz Ariadne Enes Rocha Juliane Cutrim marques Federal Institute of Education Science and Technology of Maranhao Av. Getulio Vargas District Monte Castelo Sao Luis MA65004030 Brazil department of Chemistry Federal Institute of Education Science and Technology of Maranhdo End. Av. Getulio Vargas DistrictMonte Castelo Sao Luis MA 65004030 Brazil State University of Maranhao End of University City Paulo VI Tirirical Soo Luis MA 65055970 Brazil department of Administration Federal Institute of Education Science and Technology of Maranhao End. Av. Getulio VargasDistrict Monte Castelo Sao Luis MA 65004030 Brazil department of Phytotechnology State University of Maranhao End of University City Paulo VI Tirirical Sao Luis MA 65055970Brazil

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Role of nickel-regulated small RNA in modulation of Helicobacter pylori virulence factors

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World Journal of Clinical Cases 2022年第31期10卷 11283-11291页

作者： Fabrício Freire de Melo Hanna Santos marques Fabian Fellipe Bueno Lemos Marcel Silva Luz Samuel Luca Rocha Pinheiro Lorena Sousa de carvalho Cláudio Lima Souza Márcio Vasconcelos Oliveira Institution Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029-094Brazil Campus Vitória da Conquista Universidade Estadual do Sudoeste da BahiaVitória da Conquista 45083-900Brazil

Helicobacter pylori(***)is a Gram-negative bacterium that infects about half of the world's *** infection prevails by several mechanisms of adaptation of the bacteria and by its virulence factors including the cytotoxin associated antigen A(CagA).CagA is an oncoprotein that is the protagonist of gastric carcinogenesis associated with prolonged *** *** this sense,small regulatory RNAs(sRNAs)are important macromolecules capable of inhibiting and activating gene *** function allows sRNAs to act in adjusting to unstable environmental conditions and in responding to cellular stresses in bacterial *** discoveries have shown that nickelregulated small RNA(NikS)is a post-transcriptional regulator of virulence properties of ***,including the oncoprotein ***,high concentrations of nickel cause the reduction of NikS expression and consequently this increases the levels of *** addition,NikS expression appears to be lower in clinical isolates from patients with gastric cancer when compared to patients *** that in mind,this minireview approaches,in an accessible way,the most important and current aspects about the role of NikS in the control of virulence factors of *** and the potential clinical repercussions of this modulation.

关键词： Helicobacter pylori Small regulatory RNAs Nickel-regulated small RNA Virulence factors Cytotoxin associated antigen A Gastric cancer

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Prevalence of congenital cytomegalovirus infection in preterm,small for gestational age and low birth weight newborns:characteristics and cytokines profile

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World Journal of Pediatrics 2022年第7期18卷 498-504页

作者： Janaina Fortes Lino Llian Martins Oliveira Diniz debora marques de Miranda Daniela Valadao Freitas Rosa Nathalia Gualberto Souza e Silva Eduardo de Souza Nicolau Larissa Goncalves Rezende Lais Silva carvalho Marianna Fischer de Paula Lopes Luisa Petri Correa Gabriela Mafra de Oliveira Flavia Miranda da Silva Alves Lorena Batista Pascoal Erika Lima Dolabella Teixeira da Costal Leni Marcia Anchieta Roberta Maia de Castro Romaneli Odete Valadares Maternity Hospital Belo HorizonteBrazil Pediatrics department.Faculy of Medice of Federal University of Minas Gerais Belo Horizonte.Brazil Molecular Laboratory of the INCT-MM.Faculy of Medicine.Federal University of Minas Gerais-UFMG.Belo Horizonte Brazil Faculty of Medicine.Federal University of Minas Gerais-UFMG Belo Horizonte.Brazil Risoleta Tolentino.Neves University Hospital's Maternity Belo HorizonteBrazil Sofia Feldman Maternity Hospital Belo HorizonteBrazil Hospital das Clinicas Maternity-Federal University of Minas Gerais.Belo Horizonte Brazil Pediatrics department of Federal University of Minas Gerais School Medicine.Minas Gerais.Av Professor Alfredo Balena 190.Belo Horizonte 30130-100Brazil

Cytomegalovirus is the most frequent agent of congenital viral infections,affecting approximately 0.2%-2.4%of live births in different countries[1-7].Universal screening for congenital cytomegalovirus infection in newborns is not a standard practice considering cost-benefit issues and viabil-ity of diagnostic ***,most newborns are asympto-matic and there is no effective treatment for this population[2-5].

关键词： weight birth characteristics

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Foliar application of rare earth elements on soybean(Glycine max(L)):Effects on biometrics and characterization of phytotoxicity

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Journal of Rare Earths 2020年第10期38卷 1131-1139,I0005页

作者： Eduardo S.Rodrigues Gabriel S.Montanha Joao P.R.marques Eduardo de Almeida Lauren N.M.Yabuki Amauri A.Menegario Hudson W.Pereira de carvalho Laboratory of Nuclear Instrumentation(LIN) Center for Nuclear Energy in Agriculture(CENA)University of Sao Paulo(USP)PiracicabaSP13416-000Brazil Environmental Studies Center Sao Paulo State University(UNESP)Rio ClaroSP13506-900Brazil

This study aims at investigating the effects of foliar application of aqueous solutions of La3+and Ce3+nitrates on soybean plants(Glycine max).First,we observe that Triton HW 1000 surfactant at 0.01 vol%reduces droplets contact angle and increases their drying *** greenhouse conditions,the foliar treatments do not affect chlorophyll content,plant height,number of leaves,number of pods,number of seeds per pod,and average seed ***,the treatments induce phytotoxicity since foliar injuries appear after the *** X-ray fluorescence spectroscopy combined to scanning electron microscopy shows that the leaf lesions are positively correlated to accumulation of Ce and La on the leaf surface and also promote structural alteration to the epidermal cells.X-ray absorption near edge structure shows that the La and Ce nitrates are partially bio transformed into oxides by the leaves which might explain the harmful effects.

关键词： Leaf fertilization Rare earth elements Soybean X-ray fluorescence spectroscopy X-ray absorption spectroscopy

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Turning Industrial Waste into a Valuable Bioproduct:Starch from Mango Kernel derivative to Oil Industry Mango Starch derivative in Oil Industry

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Journal of Renewable Materials 2019年第2期7卷 139-152页

作者： Nívia do Nascimento marques Caroline Suzy do Nascimento Garcia Liszt Yeltsin Coutinho Madruga Marcos Antônio Villetti Men de SáMoreira de Souza Filho Edson Noriyuki Ito Rosangela de carvalho Balaban Instituto de Química Universidade Federal do Rio Grande do Norte-UFRNNatal59078970Brazil departamento de Física Universidade Federal de Santa Maria-UFSMSanta Maria97105900Brazil Embrapa Agroindústria Tropical Fortaleza60511-110Brazil departamento de Engenharia de Materiais Universidade Federal do Rio Grande do Norte-UFRNNatal59078970Brazil

After industrial mango processing,tons of residues such as peels and kernels are discarded as ***,almost 60% of the mango kernel is due to starch on a dry weight ***,starch from mango(Manguifera Indica L.)kernel was applied to obtain a starch fatty ester with vinyl laurate,in DMSO,under basic ***,1H and 13C NMR confirmed that a starch ester with a degree of modification of 2.6 was *** showed that the modified starch has higher thermal stability than its precursors and higher than a vinyl laurate/starch physical *** data showed that granular shape and smooth surface on mango starch changed after chemical modification to a continuous and shapeless *** industrial reject derivative behaved as an efficient alternative environmentally friendly fluid loss controller in oil drilling fluids,even in conditions of high temperatures and high pressures(HTHP)drilling.

关键词： Mango Starch oil drilling fluid transesterification vinyl laurate

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Tertiary peritonitis: A disease that should not be ignored

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World Journal of Clinical Cases 2021年第10期9卷 2160-2169页

作者： Hanna Santos marques Glauber Rocha Lima Araújo Filipe Antônio França da Silva Breno Bittencourt de Brito Paulo Victor Dias Versiani Jaqueline Silva Caires Thiago de carvalho Milet Fabrício Freire de Melo Campus Vitória da Conquista Universidade Estadual do Sudoeste da BahiaVitória da Conquista 45083-900BahiaBrazil Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029-094BahiaBrazil department of Surgery Hospital Geral de Vitória da ConquistaVitória da Conquista 45029-094BahiaBrazil

Intra-abdominal infections can be classified into uncomplicated or complicated(peritonitis). Peritonitis is divided into primary, secondary, and tertiary. Tertiaryperitonitis is the less common but the most severe among peritonitisstratifications, being defined as a recurrent intra-abdominal infection that occurs48 h after a well-succeeded control of a secondary peritonitis. This disease has acomplex pathogenesis that is closely related to the capacity of the peritonealcavity to activate immunological processes. Patients who progress to persistentperitonitis are at an increased risk of developing several infectious complicationssuch as sepsis and multiple organ failure syndrome. Moreover, tertiary peritonitisremains an important cause of hospital death mainly among patients withassociated risk factors. The microbiological profile of organisms causing tertiaryperitonitis is often different from that observed in other types of peritonitis. Inaddition, there is a high prevalence of multidrug-resistant pathogens causing thiscondition, and an appropriate and successful clinical management depends on anearly diagnosis, which can be made easier with the use of clinical scorespresenting a good prediction value during the intensive care unit ***, immediate therapy should be performed to control theinfectious focus and to prevent new recurrences. In this sense, the treatment isbased on initial antimicrobial therapy and well-performed peritoneal drainage.

关键词： Tertiary peritonitis Pathogenesis Clinical manifestation Diagnosis Treatment Prognosis

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Evaluating seroprevalence to circumsporozoite protein to estimate exposure to three species of Plasmodium in the Brazilian Amazon

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Infectious Diseases of Poverty 2018年第1期7卷 448-459页

作者： Virginia Araujo Pereira Juan Camilo Sanchez-Arcila Mariana Pinheiro Alves Vasconcelos Amanda Ribeiro Ferreira Lorene de Souza Videira Antonio Teva Daiana Perce-da-Silva Maria Teresa Queiroz marques Luzia Helena de carvalho Dalma Maria Banic Luiz Cristovao Sobrino Porto Joseli Oliveira-Ferreira Laboratory of Immunoparasitology Oswaldo Cruz Institute/FiocruzAv.Brasil 4365ManguinhosRio de JaneiroBrazil Institute of Infectology Emilio Ribas São PauloSao PauloBrazil Laboratory of Immunodiagnosis Departament of Biological SciencesNational School of Public Health/FiocruzRio de JaneiroBrazil Laboratory of Clinical Immunology Oswaldo Cruz Institute/FiocruzRio de JaneiroBrazil Laboratory of Histocompatibility and Cryopreservation–HLA of DHE/IBRAG/UERJ Rio de JaneiroBrazil Molecular Biology and Malaria Immunology Research Group Centro de Pesquisas Rene Rachou/FiocruzBelo HorizonteMinas GeraisBrazil

Background:Brazil has seen a great decline in malaria and the country is moving towards ***,for eventual elimination,the control program needs efficient tools in order to monitor malaria exposure and *** this study,we aimed to evaluate whether seroprevalence to the circumsporozoite protein(CSP)is a good tool for monitoring the exposure to and/or evaluating the burden and distribution of Plasmodium species in the Brazilian ***:Cross-sectional surveys were conducted in a rural area of Porto Velho,Rondônia *** infection was detected by microscopy and polymerase chain *** to the sporozoite CSP repeats of Plasmodium vivax,***,and ***(PvCS,PfCS,and PmCS)were detected using the enzyme-linked immunosorbent assay *** leukocyte antigen(HLA)-DRB1 and DQB1 genes were typed using Luminex®xMAP®***:The prevalence of immunoglobulin G against *** CSP peptide(62%)was higher than ***(49%)and ***(46%)CSP *** of the studied individuals had antibodies to at least one of the three peptides(72%),34%had antibodies to all three peptides and 28%were *** the majority of the population was not infected at the time of the survey,74.3%of parasite-negative individuals had antibodies to at least one of the ***,among individuals carrying the haplotypes DRB1*04~DQB1*03,there was a significantly higher frequency of PfCS responders,and DRB1*16~DQB1*03 haplotype for PvCS and PfCS *** contrast,HLA-DRB1*01 and HLA-DQB1*05 allelic groups were associated with a lack of antibodies to *** and *** CSP repeats,and the haplotype DRB1*01~DQB1*05 was also associated with non-responders,including non-responders to ***:Our results show that in low transmission settings,naturally acquired antibody responses against the CSP repeats of ***,***,and *** in a single cross-sectional study may n

关键词： Malaria Circumsporozoite protein Serological marker Human leucocyte antigen IgG antibody Porto Velho Rondônia Brazil

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Urban Settlement Spatial Analysis in Permanent Preservation Area of M’boicy Watershed River, Foz do Iguaçu City in Brazil

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International Journal of Geosciences 2016年第10期7卷 1222-1231页

作者： Luis Henrique Weiss de carvalho Sandro Laudares Matheus Pereira Libório Marianna Petrovna Ekel Renato de Oliveira marques Geoprocessing GeoInnovit Solucoes Tecnológicas Foz do Iguacu Brazil department of Geoghaphy Pontifical Catholic University of Minas Gerais Belo Horizonte Brazil department of Distance Learning Pontifical Catholic University of Minas Gerais Belo Horizonte Brazil Research Support Foundation of Minas Gerais Belo Horizonte Brazil

Irregular urban settlement increases environmental impacts, especially when these occupations occur in fragile location, as the environmental preservation areas. In these areas, also defined as Permanent Preservation Area (PPA), the presence of watersheds is common, which is the factor that increases the need of protecting them from anthropic actions. Those actions deteriorate the environment and mainly the watercourses. This research objective is to identify and estimate the environmental risks of M’Boyci watershed River PPA occupied areas by urban population. The risk analysis approach, at this PPA in Foz do Iguacu City in Brazil, is able to support public interventions in order to reestablish the PPA natural conditions. To reach this goal, it was necessary to use cartographical representation images, generated from digital orthophotos analyzed through free geographical information systems. The overlap and the contrast of geographical data related to preservation in urban areas show that urban occupation reaches almost 40% of the permanent preservation area. Complementarily, it is evidenced that the development of a risk map identifies PPA areas characterized by a greater concentration of irregular settlement, contributing to the planning process of residents, relocation actions and recovery of degraded areas.

关键词： Urban Settlement Permanent Preservation Areas Environmental Impact Spatial Analysis Geographical Information System

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Effects of nutrients on immunomodulation in patients with severe COVID-19:Current knowledge

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World Journal of Critical Care Medicine 2022年第4期11卷 201-218页

作者： Bruna Teixeira da Costa Glauber Rocha Lima Araújo Ronaldo Teixeira da Silva Júnior Luana Kauany de SáSantos Vinícius Lima de Souza Gonçalves Daniel Bastos Alves Lima Beatriz Rocha Cuzzuol Jonathan Santos Apolonio Lorena Sousa de carvalho Hanna Santos marques Camilo Santana Silva Isadora de Souza Barcelos Márcio Vasconcelos Oliveira Fabrício Freire de Melo Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029-094BahiaBrazil Campus Vitória da Conquista Universidade Estadual do Sudoeste da BahiaVitória da Conquista 45083-900BahiaBrazil

Recent research has demonstrated that critically ill patients with coronavirus disease 2019(COVID-19)show significant immune system *** to that,some nutrients that influence immunomodulation have been suggested as a form of treatment against the *** review collected the information on the impact of vitamins on the prognosis of COVID-19,with the intention of facilitating treatment and prevention of the disease risk status in *** collected information was obtained using the PubMed electronic database by searching for articles that relate COVID-19 and the mechanisms/effects of the nutrients:Proteins,glucose,lipids,vitamin B12,vitamin D,calcium,iron,copper,zinc,and magnesium,including prospective,retrospective,and support *** findings reveal an optimal response related mainly to omega-3,eicosapentaenoic acid,docosahexaenoic acid,calcium,and iron that might represent benefits in the treatment of critically ill ***,nutrient supplementation should be done with caution due to the limited availability of randomized controlled studies.

关键词： COVID-19 Immunomodulation Patient care Vitamins Nutrients Micronutrients

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Transmission of severe acute respiratory syndrome coronavirus 2 via fecal-oral:Current knowledge

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World Journal of Clinical Cases 2021年第28期9卷 8280-8294页

作者： Filipe Antônio França da Silva Breno Bittencourt de Brito Maria Luísa Cordeiro Santos Hanna Santos marques Ronaldo Teixeira da Silva Júnior Lorena Sousa de carvalho Samuel de Sousa Cruz Gabriel Reis Rocha Gabriel Lima Correa Santos Kathlen Coutinho de Souza Rebeca Gabrielle Almeida Maciel Daiana Silva Lopes Natália Oliveira e Silva Márcio Vasconcelos Oliveira Fabrício Freire de Melo Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45002175BahiaBrazil departamento de Ciências Naturais Universidade Estadual do Sudoeste da BahiaVitória da Conquista 45002175BahiaBrazil departamento de Bioquímica e Biofísica Universidade Federal da BahiaSalvador 40.110-100BahiaBrazil Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029-094BahiaBrazil

The pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has resulted in more than 93 million cases and 2 million deaths in the ***-CoV-2 respiratory tract infection and its main clinical manifestations such as cough and shortness of breath are well known to the scientific ***,a growing number of studies have reported SARS-CoV-2-related gastrointestinal involvement based on clinical manifestations,such as diarrhea,nausea,vomiting,and abdominal pain as well as on the pathophysiological mechanisms associated with coronavirus disease ***,current evidence suggests SARS-CoV-2 transmission via the fecal-oral route and aerosol ***,studies have shown a high risk of contamination through hospital surfaces and personal ***,viable SARS-CoV-2 specimens can be obtained from aerosols,which raises the possibility of transmission through aerosolized viral particles from ***,the infection by SARS-CoV-2 via fecal-oral route or aerosolized particles should *** addition,a possible viral spread to sources of drinking water,sewage,and rivers as well as the possible risk of viral transmission in shared toilets become a major public health concern,especially in the least developed *** authors have emphasized the presence of viral RNA and even viable SARS-CoV-2 in human feces,studies on the possible fecal-oral coronavirus disease 2019 transmission become essential to understand better the dynamics of its transmission and,then,to reinforce preventive measures against this infection,leading to a more satisfactory control of the incidence of the infection.

关键词： COVID-19 SARS-CoV-2,Transmission Via fecal-oral

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