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Multimodal Fuzzy Downstream Petroleum Supply Chain:A Novel Pentagonal Fuzzy Optimization

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Computers, Materials & Continua 2023年第3期74卷 4861-4879页

作者： Gul Freen Sajida Kousar Nasreen Kausar Dragan Pamucar georgia irina oros Department of Mathematics and Statistics International Islamic UniversityIslamabadPakistan Department of Mathematics Faculty of Arts and SciencesYildiz Technical UniversityEsenlerIstanbul34210Turkey Department of Logistics University of Defence in BelgradeBelgradeSerbia Department of Mathematics and Computer Science University of OradeaOradea410087Romania

The petroleum industry has a complex,inflexible and challenging supply chain(SC)that impacts both the national economy as well as people’s daily lives with a range of services,including transportation,heating,electricity,lubricants,as well as chemicals and *** the petroleum industry,supply chain management presents several challenges,especially in the logistics sector,that are not found in other *** addition,logistical challenges contribute significantly to the cost of *** regarding customer demand and supply significantly affects SC ***,SC flexibility can be maintained by addressing *** the other hand,in the real world,decision-making challenges are often ambiguous or *** some cases,measurements are incorrect owing to measurement errors,instrument faults,etc.,which lead to a pentagonal fuzzy number(PFN)which is the extension of a fuzzy ***,it is necessary to develop quantitative models to optimize logistics operations and supply chain *** study proposed a linear programming model under an uncertain *** model minimizes the cost along the refineries,depots,multimode transport and demand *** developed pentagonal fuzzy optimization,an alternative approach is developed to solve the downstream supply chain using themixed-integer linear programming(MILP)model to obtain a feasible solution to the fuzzy transportation cost *** this model,the coefficient of the transportation costs and parameters is assumed to be a pentagonal fuzzy ***,defuzzification is performed using an accuracy *** validate the model and technique and feasibility solution,an illustrative example of the oil and gas SC is considered,providing improved results compared with existing techniques and demonstrating its ability to benefit petroleum companies is the objective of this study.

关键词： Downstream petroleum supply chain fuzzy optimization multimodal optimization pentagonal fuzzy number

Recovery of high-purity Pt from Pt-Au bimetallic nanoparticles using organic aqua regia

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Rare Metals 2012年第1期31卷 92-95页

作者： LIN Wei School of Materials Science & Engineering,georgia Institute of Technology,Atlanta,georgia,30332,USA School of Materials Science & Engineering Georgia Institute of Technology Atlanta USA

Using organic aqua regia,a recently discovered powerful organic leaching agent,an effective process of recovering Pt directly from Pt-Au bimetallic nanoparticles was *** purities of the Pt recovered from a mixture of Au and Pt nanoparticles and from Pt-Au core-shell nanoparticle catalyst are as high as (99.49±0.22)%,and (95.02±0.08)%,*** novel recovery process promises applications in catalysis industry.

关键词： organic aqua regia bimetallic platinum gold nanoparticle recovery

Corticosteroid-free immunosuppression in liver transplantation: An evidence-based review

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World Journal of Gastroenterology 2014年第31期20卷 10703-10714页

作者： George Sgourakis georgia Dedemadi 2~(nd) Surgical Department and Surgical Oncology Unit "Korgialenio-Benakio" Red Cross Hospital Surgical Department of "Amalia Fleming" General Hospital

Thirty-six randomized controlled trials and two metaanalyses were reviewed. With respect to adult patients undergoing first orthotopic liver transplantation(OLT), steroid replacement resulted in fewer cases of overall acute rejection in the corticosteroid free-immunosuppression arm. Initial steroid administration for two weeks and early tacrolimus monotherapy is a feasible immunosuppression regimen without steroid replacement, although further investigations are needed in view of chronic rejections. No significant differences were noted between the treatment groups in terms of patient and graft survival independently of steroid replacement. Renal insufficiency, de novo hypertension, neurological disorders and infectious complications did not differ significantly among steroid and steroidfree groups. Diabetes mellitus, cholesterol levels and cytomegalovirus infection are more frequent in patients within the steroid group. With respect to diabetes mellitus and hypercholesterolemia, the difference was independent of steroid replacement. In relation to transplanted hepatitis C virus patients, mycophenolate mofetil does not appear to have a significant antiviral effect despite early reports. Male gender of donors and recipients, living donors, cold ischemia times, acute rejection, and early histological recurrence were related to the development of advanced hepatitis. There is sufficient scientific clinical evidence advocating avoidance of the ab initio use of steroids in OLT.

关键词： Meta-analysis Evidence based Hepatitis C virus recurrence Liver transplantation Steroid withdrawal Orthotopic liver transplantation

Trans-Golgi Network-An Intersection of Trafficking Cell Wall Components

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Journal of Integrative Plant Biology 2012年第11期54卷 875-886页

作者： Natasha Worden Eunsook Park georgia Drakakaki Department of Plant Sciences University of CaliforniaDavis 95616USA

The cell wall, a crucial cell compartment, is composed of a network of polysaccharides and proteins, providing structural support and protection from external stimuli.

关键词： Cell wall chemical genomics endomembrane trafficking trans-Golgi network vesicle proteomics.

Thermal Diversities of Two Na^+/H^+ Exchanges in Guinea Pig Red Cells

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Biomedical and Environmental Sciences 2001年第3期14卷 171-179页

作者： JI HONG-LONG 1Department of Cellular Biology, University of georgia, Athens, georgia 30602, USA Department of Cellular Biology University of Georgia Athens Georgia 30602 USA. ji@physiology.uab.edu

Objective\ To test the effect of hypothermia on Na+/H+ exchange, activated by shrinkage and cytoplasmic acidosis. Method\ Amiloride-sensitive Na+ influx in guinea pig red cells was traced with isotope 22Na and intracellular Na+ concentration was measured by emission flame photometry. Result\ Amiloride-sensitive Na+ influx decreased linearly as a function of temperatures (about 37℃) in shrunken cells, but increased in acidified cells. The up-regulation of acid-induced Na+/H+ exchange by elevated temperature was enhanced by hypo-osmolarity. Less sensitivity of intracellular H+ site at 41℃ may be the mechanism for the inhibition of shrinkage-induced Na+/H+ exchange by elevated temperature. Heating-mediated explosive increase in the activity of acid-induced Na+/H+ exchange may be due to enhanced extracellular Na+ sensitivity and lower intracellular pH caused by acidic metabolites. Acid-induced Na+/H+ ewxchange contributes to cytoplasmic Na+ accumulation. Conclusion\ These two modes of Na+/H+ exchange with different response to elevated temperature may play different roles in the cellular pathogenesis of heatstroke.

关键词： Animals Cell Culture Techniques Erythrocytes Guinea Pigs Heat Stroke Hydrogen Ion Exchange Research Support, U.S. Gov't, Non-P.H.S. Sodium Temperature

PTPN22 and islet-specific autoimmunity:What have the mouse models taught us?

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World Journal of Diabetes 2017年第7期8卷 330-336页

作者： Giuseppe Galvani georgia Fousteri Diabetes Research Institute IRCCS San Raffaele Scientific Institute20132 MilanItaly

An allelic variant of the protein tyrosin phosphatase non-receptor 22(PTPN22) gene, PTPN22 R620 W, constitutes the strongest non-HLA genetic risk factor for the development of type 1 diabetes(T1D). A numberstudies using mouse models have addressed how PTPN22 predisposes to T1D. PTPN22 downmodulation, overexpression or expression of the variant gene in genetically manipulated mice has generated controversial results. These discrepancies probably derive from the fact that PTPN22 has differential effects on innate and adaptive immune responses. Moreover, the effects of PTPN22 are dependent on other genetic variables. Here we discuss these findings and try to explain the discrepancies. Exploring the mechanism by which PTPN22 contributes to islet-specific autoimmunity could help us understand its role in T1D pathogenesis and exploit it as a potential therapeutic target to prevent the disease.

关键词： Protein tyrosin phosphatase non-receptor 22 Type 1 diabetes Genetic susceptibility Mouse model Autoimmunity Islet-specific autoimmunity

Recent advances in pharmacological treatment of irritable bowel syndrome

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World Journal of Gastroenterology 2014年第27期20卷 8867-8885页

作者： georgia Lazaraki Grigoris Chatzimavroudis Panagiotis Katsinelos Department of Endoscopy and Motility Unit G. Gennimatas General Hospital School of Medicine Aristotle University of Thessaloniki

Irritable bowel syndrome (IBS) is a highly prevalent functional disorder that reduces patients’ quality of life. It is a chronic disorder characterized by abdominal pain or discomfort associated with disordered defecation in the absence of identifiable structural or biochemical abnormalities. IBS imposes a significant economic burden to the healthcare system. Alteration in neurohumoral mechanisms and psychological factors, bacterial overgrowth, genetic factors, gut motility, visceral hypersensitivity, and immune system factors are currently believed to influence the pathogenesis of IBS. It is possible that there is an interaction of one or more of these etiologic factors leading to heterogeneous symptoms of IBS. IBS treatment is predicated upon the patient’s most bothersome symptoms. Despite the wide range of medications and the high prevalence of the disease, to date no completely effective remedy is available. This article reviews the literature from January 2008 to July 2013 on the subject of IBS peripherally acting pharmacological treatment. Drugs are categorized according to their administration for IBS-C, IBS-D or abdominal pain predominant IBS.

关键词： Irritable bowel syndrome Irritable bowel syndrome constipation Irritable bowel syndrome-diarrhea Constipation Diarrhea Irritable bowel syndrome treatment Irritable bowel syndrome-pain

Rare earth elements(REE)and isotope composition(δ^(13)C andδ^(18)O)of manganese ores of Chiatura deposit(georgia):features of ore formation and genesis

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Acta Geochimica 2023年第4期42卷 779-801页

作者： Vladimir N.Kuleshov Andrey Yu.Bychkov irina Yu.Nikolaeva Maria E.Tarnopolskaya Geological Institute Russian Academy of SciencesPyzhevskii Per.7MoscowRussia 119017 Lomonosov Moscow State University Leninskie Gory1MoscowRussia 119899

The rare earth elements(REE)geochemistry and the isotope(δ^(13)C,δ^(18)O)composition of manganese ores of the Chiatura(georgia)deposit were *** of the major features of all types of manganese ores is negative cerium(Ce/Ce*_(PAAS))anomaly and the absence of europium(Eu/Eu*_(PAAS))*** oolitic manganese ores were formed in oxic shallow marine *** content and distribution of REEs(in particular Ce and Eu)in these ores are connected mainly with ferrous *** performed C-and O-isotope research in Mn-carbonates(oolitic and massive)has indicated that carbonate ores were formed by the participation of isotopic ally light CO_(2)which is a result of the oxidation of organic matter in the sediment strata by reducing environments of early diagenesis(and,partially,catagenesis)*** negative cerium anomalies in the studied carbonate ores reflect the specific REE patterns in pore waters of sediments of earlier isdiagenesis zone of the Oligocene Chiatura's *** deficiency of cerium in this zone remains debatable and requires further *** of manganese carbonates took place multistage by the input of incisional solutions of different chemistry into sea bottom waters and *** absence of europium anomaly indicates about lack of hydrothermal solution input.

关键词： REE Cerium anomaly Carbon and oxygen isotope geochemistry Oxide and carbonate manganese ores Chiatura deposit

Energy storage and harvesting in BaTiO_(3)/epoxy nanodielectrics

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High Voltage 2016年第4期1卷 151-157页

作者： georgia C.Manika Georgios C.Psarras Department of Materials Science University of Patras26504PatrasGreece

Composite nanodielectrics consisted of an epoxy resin and barium titanate nanoparticles were developed and *** measurements were performed via broadband dielectric *** results reveal the presence of three relaxation processes,which are attributed to(a)glass to rubber transition of the polymer matrix(α-mode),(b)re-arrangement of polar side groups(β-mode)and(c)interfacial polarisation between system’s *** ability of the examined nanodielectrics to store and harvest energy was also examined in dc *** dc voltage varied in the range of 10–240 *** data indicate that increasing the applied dc field results to higher values of the stored and harvested *** energy efficiency was also investigated in all *** filler content enhances the coefficient of energy efficiency(neff)up to 58.2%for the 7 phr BaTiO_(3)nanocomposite at 200 V and 10 s charging/discharging time.

关键词： spectroscopy. rubber arrangement