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Effect of autologous serum after amniotic membrane transplantation for persistent corneal ulcers

International Journal of Ophthalmology(English edition) 2024年第9期17卷 1639-1644页

作者： Rozaliya Hristova Petya Yankova georgi markov Alexander Oscar Yani Zdravkov Department of Ophthalmology Medical University SofiaUniversity Hospital AlexandrovskaSofia 1431Bulgaria Department of Clinical Immunology Medical University SofiaUniversity Hospital AlexandrovskaSofia 1431Bulgaria

AIM:To investigate the effect of adding autologous serum eye drops to the postoperative regime after amniotic membrane transplantation for severe persistent corneal ***:Forty eyes of 40 patients with persistent corneal ulcers were randomly assigned to artificial tears(sodium hyaluronate 0.2%,ATs group,n=20)or autologous serum eye drops(ASEDs,n=20)following treatment with amniotic membrane *** slit lamp images were acquired from all patients before and 30d post *** area with fibrovascular tissue was calculated using Image *** corneal sensitivity was assessed by Cochet-Bonnet aesthesiometry before and one month after *** tissue transparency was assessed with a novel optical ***:Mean age of patients was 61.65±16.47y and 57.3±19.11y in the ATs group and ASEDs group,***-two male and 18 female patients were included in the *** improvement in visual acuity was significantly greater in the ASEDs group(0.14±0.04)than the ATs(0.08±0.04;P=0.00046).Cochet-Bonnet aesthesiometry improved significantly after treatment with a similar rate between *** were no statistically significant differences in the area of postoperative fibrovascular tissue between the two groups(P=0.082).The success rate in the two groups was *** difference in densitometry between the ATs and ASEDs group was statistically significant(P=0.042)with greater reduction from baseline in the ASEDS ***:Autologous serum eye drops can lead to better visual acuity,more stable results and improved densitometry and should be considered in the postoperative care following amniotic membrane transplantation.

关键词： autologous serum amniotic membrane ocular surface persistent corneal ulcer

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Decentralized adaptive synchronization of an uncertain complex delayed dynamical network

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控制理论与应用（英文版） 2009年第3期7卷 225-230页

作者： georgi M. DIMIROVSKI Department of Computer Engineering Dogus University

In this paper, we investigate the locally and globally adaptive synchronization problem for an uncertain complex dynamical network with time-varying coupling delays based on the decentralized control. The coupling terms here are bounded by high-order polynomials with known gains that are ubiquitous in a large class of complex dynamical networks. We generalize the usual technology of searching for an appropriate coordinates transformation to change the network dynamics into a series of decoupled lower-dimensional systems. Several adaptive synchronization criteria are derived by constructing the Lyapunov-Krasovskii functional and Barbalat lemma, and the proposed criteria are simple in form and convenient for the practical engineering design. Numerical simulations illustrated by a nearest-neighbor coupling network verify the effectiveness of the proposed synchronization scheme.

关键词： Complex dynamical networks Synchronization Adaptive control Decentralized control

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H∞ Tracking Control for Switched LPV Systems With an Application to Aero-Engines

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IEEE/CAA Journal of Automatica Sinica 2018年第3期5卷 699-705页

作者： Kongwei Zhu Jun Zhao georgi M.Dimirovski State Key Laboratory of Synthetical Automation for Process Industries (Northeastern University) College of Information Science and Engineering Northeastern University Shenyang 110819 China School of Informatics Linyi University Linyi 276000 China School of Engineering Dogus University and also with the School of Electrical-Electronics Engineering and Information Technologies St. Cyril and St. Methodius University Skopje Macedonia Istanbul TR-34722 R. Turkey IEEE

This paper focuses on the H_∞ model reference tracking control for a switched linear parameter-varying(LPV)model representing an aero-engine. The switched LPV aeroengine model is built based on a family of linearized *** parameter-dependent Lyapunov functions technique is used to design a tracking control law for the desirable H_∞ tracking performance. A control synthesis condition is formulated in terms of the solvability of a matrix optimization *** result on the aero-engine model shows the feasibility and validity of the switching tracking control scheme.

关键词： Aero-engine control H_∞ tracking control multiple parameter-dependent Lyapunov functions switched linear parameter-varying(LPV) systems

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Correction of source-rock permeability measurements owing to slip flow and Knudsen diffusion: a method and its evaluation

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Petroleum Science 2018年第1期15卷 116-125页

作者： Hui-Hai Liu Dan georgi Jinhong Chen Aramco Research Centers – Houston Aramco Services Company

Source-rock permeability is a key parameter that controls the gas production rate from unconventional reservoirs. Measured source-rock permeability in the laboratory, however, is not an intrinsic property of a rock sample, but depends on pore pressure and temperature as a result of the relative importance of slip flow and diffusion in gas flow in lowpermeability media. To estimate the intrinsic permeability which is required to determine effective permeability values for the reservoir conditions, this study presents a simple approach to correct the laboratory permeability measurements based on the theory of gas flow in a micro/nano-tube that includes effects of viscous flow, slip flow and Knudsen diffusion under different pore pressure and temperature conditions. The approach has been verified using published shale laboratory *** ＇＇corrected＇＇（or intrinsic） permeability is considerably smaller than the measured permeability. A larger measured permeability generally corresponds to a smaller relative difference between measured and corrected permeability values. A plot based on our approach is presented to describe the relationships between measured and corrected permeability for typical Gas Research Institute permeability test conditions. The developed approach also allows estimating the effective permeability in reservoir conditions from a laboratory permeability measurement.

关键词： Shale gas Permeability Knudsen diffusion Unconventional reservoir Source rock

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Insights into glymphatic system dysfunction and glucose continuum

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World Journal of Diabetes 2024年第12期15卷 2404-2408页

作者： Tsvetelina Velikova georgi Vasilev Medical Faculty Sofia University St.Kliment OhridskiSofia 1407Bulgaria Clinic of Neurology and Department of Emergency Medicine UMHAT"Sv.Georgi"Plovdiv 4000Bulgaria

In this article,we comment on an original article published in a recent issue of the World Journal of *** observational cross-sectional study focused on investigating the function of the glymphatic system and its clinical correlates in patients with different glucose metabolism states by using diffusion tensor imaging along the perivascular space(DTI-ALPS)*** was shown that the cerebral glymphatic system may be dysfunctional in patients with type 2 *** clinical variables affected the DTI-ALPS index in different glucose metabolism *** conclusion,the study by Tian et al improves the under-standing of the pathophysiology of diabetes-associated brain damage and pro-vides insights for early diagnosis.

关键词： Glymphatic system Prediabetes Type 2 diabetes mellitus Magnetic reso-nance imaging Diffusion tensor imaging along the perivascular space

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Landscape alteration affects the demography of an endangered avian predator by reducing the habitat quality

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Avian Research 2022年第2期13卷 194-201页

作者： Dimitar Demerdzhiev Dobromir Dobrev georgi Popgeorgiev Stoycho Stoychev Bulgarian Society for the Protecaon of Birds/Birdlife Bulgaria 5 Leonardo Da Vinci Str.Plovdiv4000Bulgaria National Museum of Natural History Department of ZoologySofiaBulgaria

Habitat transformation is identified as major threat to biodiversity loss globally,affecting threatened *** in land use can alter the abundance and distribution of birds of prey by affecting habitat availability and *** this study,we used multivariate analyses to investigate the effect of habitat alteration on the demography of a declining Eastern Imperial Eagle(Aqufla heliaca),making assumptions for future population *** used the Generalized Linear Mixed Models with Poisson distribution and Log link function,searching a relationship between the demographic parameters and the landscape structure and possible effects of *** our study area,habitat change affected dramatically permanent grasslands,shrinking their *** we expected,the share of grasslands in eagles’territories significantly affected occupancy rate,but not productivity and breeding *** found that occupancy rate decreased significantly,while productivity and breeding frequency showed no *** the effect of habitat alteration on Eastern Imperial Eagle demography,we found out that territory quality was a more powerful factor driving the response of a top predator to the alteration of favorite foraging *** the habitat quality in source territories had a significant positive effect on eagle *** found that simple rules to predict adverse agricultural impact on territory abandonment or breeding productivity of a top predator were not *** results could be used for planning conservation of other large territorial raptors,facing the same type of threat.

关键词： Eastern imperial eagle Habitat transformation Population dynamics Raptor demography Source-sink system

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AM_2O_8(A=Zr,Hf;M=Mo,W)氧化物粉体的低温液相合成及其结构控制(英文)

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硅酸盐学报 2009年第5期37卷 667-674页

作者： georgi Christian 伊尔梅瑙理工大学材料工艺研究所德国伊尔梅瑙98693

立方AM2O8氧化物(A=Zr,Hf;M=Mo,W)是最有希望的一类负热膨胀材料。为开发这类材料,期望获得高质量AM2O8粉体,而传统固相合成法不能达到这一目的。低温液相合成法是一种有望合成高质量AM2O8氧化物粉体的途径。本文介绍了1998年以来低温... 详细信息

立方AM2O8氧化物(A=Zr,Hf;M=Mo,W)是最有希望的一类负热膨胀材料。为开发这类材料,期望获得高质量AM2O8粉体,而传统固相合成法不能达到这一目的。低温液相合成法是一种有望合成高质量AM2O8氧化物粉体的途径。本文介绍了1998年以来低温液相合成AM2O8粉体的研究进展,首先,概述了AM2O7(OH)2·2H2O脱水的合成工艺,其后讨论了用于制备醇盐或羧酸盐前驱体的凝胶技术。着重讨论了材料结构控制问题,并提出了进一步研究方向。

关键词：溶胶-凝胶合成负热膨胀钨酸锆钼酸锆

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Lateral epicondylitis:New trends and challenges in treatment

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World Journal of Orthopedics 2022年第4期13卷 354-364页

作者： Vesselin Karabinov georgi P georgiev Clinic of Neurology National Cardiology HospitalSofia 1000Bulgaria Department of Orthopedics and Traumatology University Hospital Queen Giovanna-ISULMedical University of SofiaSofia 1527Bulgaria

Lateral epicondylitis(LE)is a chronic aseptic inflammatory condition caused by repetitive microtrauma and excessive overload of the extensor carpi radialis brevis *** is the most common cause of musculoskeletal pain syndrome in the elbow,inducing significant pain and limitation of the function of the upper *** affects approximately 1-3%of the population and is frequently seen in racquet sports and sports associated with functional overload of the elbow,such as tennis,squash,gymnastics,acrobatics,fitness,and weight ***,artists,musicians,electricians,mechanics,and other professions requiring frequent repetitive movements in the elbow and wrists are also *** is a leading causation for absence from work and lower sport results in *** treatment includes a variety of conservative measures,but if those fail,surgery is *** review summarizes the knowledge about this disease,focusing on risk factors,expected course,prognosis,and conservative and surgical treatment approaches.

关键词： Diagnosis Lateral epicondylitis Tennis elbow Treatment Review

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Light and electron microscopic study of the medial collateral ligament epiligament tissue in human knees

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World Journal of Orthopedics 2017年第5期8卷 372-378页

作者： georgi P georgiev Alexandar Iliev georgi Kotov Plamen Kinov Svetoslav Slavchev Boycho Landzhov Department of Orthopaedics and Traumatology University Hospital Queen Giovanna-ISULMedical University of Sofia Department of Anatomy Histology and Embryology Medical University of Sofia University Hospital of Orthopaedics "Prof. B. Boychev" Medical University of Sofia

AIM To examine the normal morphology of the epiligament tissue of the knee medial collateral ligament(MCL) in humans. METHODS Several samples of the mid-substance of the MCL of the knee joint from 7 fresh human cadavers(3 females and 4 males) were taken. Examination of the epiligament tissue was conducted by light microscopy and photomicrography on semi-thin sections of formalin fixed paraffin-embedded blocks that were routinely stained with haematoxylin and eosin, Mallory stain and Van Gieson's stain. Electron microscopy of the epiligament tissue was performed on ultra-thin sections incubated in 1% osmium tetroxide and contrasted with 2.5% uranyl acetate, lead nitrate, and sodium *** The current light microscopic study demonstrated that the epiligament of the MCL consisted of fibroblasts, fibrocytes, adipocytes, neuro-vascular bundles and numerous multidirectional collagen fibers. In contrast, the ligament body was poorly vascularised, composed of hypo-cellular fascicles which were formed of longitudinal groups of collagen fibers. Moreover, most of the vessels of the epiligament-ligament complex were situated in the epiligament tissue. The electron microscopic study revealed fibroblasts with various shapes in the epiligament substance. All of them had the ultrastructural characteristics of active cells with large nuclei, well developed rough endoplasmic reticulum, multiple ribosomes, poorly developed Golgi apparatus, elliptical mitochondria and oval lysosomes. The electron microscopy also confirmed the presence of adipocytes, mast cells, myelinated and unmyelinated nerve fibers and chaotically oriented collagen *** Significant differences exist between the normal structure of the ligament and the epiligament whose morphology and function is to be studied further.

关键词： Knee Epiligament Knee medial collateral ligament Electron Microscopy Humans Microscopy Photomicrography

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Policy-Making and the Effect on Public and Private Incubator Programs in Israel:A Qualitative Comparative Analysis Study

Policy-Making and the Effect on Public and Private Incubator...

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作者： Gabriel(georgi) Rijinachvili 上海交通大学

学位级别：硕士

The aim of this thesis is to analyze policies and approach and their effect on private and public incubator programs in *** this analysis,a division of the public and private sector will *** thesis will also review the concept of innovation and entrepreneurial passion due to the fact that it is a key component for the vast incubator programs phenomena in *** technological incubators are subject to the laws of the Office of the Chief Scientist,whereas private incubators which also operate in Israel established by private bodies and free of the conditions and regulations that government incubators are obligated to comply *** thesis analyzes the influence of Israel’s incubator policies and will try comparing their *** methodology consists of four case-studies,qualitative analysis of two private sector incubators and two of the public sector incubators,government policies regarding incubation initiative and a ***,the results expose if the incubator policies are effective for public incubators in Israel and also reveal how existing policy frameworks affects on the encouragement of the state for technological *** conclusion,this thesis focuses on technological innovation and the encouragement of the Government and the Innovation Authority,formerly the Chief *** such as technological incubators,incentives for start-ups will be *** research hopes to provide a clear insight of the effectiveness of the existing policies regarding incubation programs and seeks to recommend a change in policies,due to the fast-growing phenomena of the establishment of incubators in the Start-up Nation.

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