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Robotic-assisted retroperitoneal lymph node dissection for stage II testicular cancer

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Asian Journal of Urology 2024年第1期11卷 121-127页

作者： george McClintock Ahmed s.Goolam Don Perera Ryan Downey scott Leslie Peter Grimison Henry Woo Peter Ferguson Nariman Ahmadi Department of Urology Chris O'Brien LifehouseSydneyNSWAustralia Department of Anaesthesia Chris O'Brien LifehouseSydneyNSWAustralia The University of sydney SydneyNSW2006Australia Department of Medical Oncology Chris O'Brien LifehouseSydneyNSWAustralia

Objective:To evaluate the perioperative as well as early oncological outcomes of patients undergoing robotic retroperitoneal lymph node dissection for treatment of testicular ***:We conducted a prospective consecutive case series of patients undergoing robotic assisted retroperitoneal lymph node dissection for metastatic testicular cancer between May 2018 and July 2021 at our *** were collected on patient and tumour characteristics,intraoperative and postoperative parameters,and functional and oncological *** statistics are ***:Nineteen patients were identified;18(94.7%)completed the procedure robotically and one was converted to open surgery;78.9%of patients had stage≥IIB and 12(63.2%)patients had undergone prior *** median operative time was 300(interquartile range[IQR]240-315)*** blood loss was 100(IQR 50-175)*** length of stay was 2(range 1-11)*** robotically completed patients commenced diet and passed flatus on Day 1 and were discharged by Day *** median lymph node yield was 40.5(IQR 38-51)*** patients undergoing nerve-sparing procedures recovered antegrade ejaculatory *** patient had a Clavien-Dindo III complication(chylous ascites requiring drainage).At a median follow-up of 22.3(IQR 16.3-24.9)months,one patient developed retroperitoneal recurrence,which was successfully treated with second-line chemotherapy;no other patients have had ***:Robotic retroperitoneal lymph node dissection is a safe and feasible alternative to open surgery in appropriately selected patients,offering low *** oncological outcomes are *** cohorts and longer follow-ups are required to validate our institution's findings.

关键词： Retroperitoneal lymph node dissection Robotic surgery Testicular cancer Retroperitoneal node dissection

A Dimensional Reduction Approach Based on Essential Constraints in Linear Programming

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American Journal of Operations Research 2024年第1期14卷 1-31页

作者： Eirini I. Nikolopoulou george s. Androulakis Department of Mathematics University of Patras Patras Greece Department of Business Administration University of Patras Patras Greece

This paper presents a new dimension reduction strategy for medium and large-scale linear programming problems. The proposed method uses a subset of the original constraints and combines two algorithms: the weighted average and the cosine simplex algorithm. The first approach identifies binding constraints by using the weighted average of each constraint, whereas the second algorithm is based on the cosine similarity between the vector of the objective function and the constraints. These two approaches are complementary, and when used together, they locate the essential subset of initial constraints required for solving medium and large-scale linear programming problems. After reducing the dimension of the linear programming problem using the subset of the essential constraints, the solution method can be chosen from any suitable method for linear programming. The proposed approach was applied to a set of well-known benchmarks as well as more than 2000 random medium and large-scale linear programming problems. The results are promising, indicating that the new approach contributes to the reduction of both the size of the problems and the total number of iterations required. A tree-based classification model also confirmed the need for combining the two approaches. A detailed numerical example, the general numerical results, and the statistical analysis for the decision tree procedure are presented.

关键词： Linear Programming Binding Constraints Dimension Reduction Cosine similarity Decision Analysis Decision Trees

Probiotics: shaping the gut immunological responses

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World Journal of Gastroenterology 2024年第15期30卷 2096-2108页

作者： Eirini Filidou Leonidas Kandilogiannakis Anne shrewsbury george Kolios Katerina Kotzampassi Faculty of Medicine Laboratory of PharmacologyDemocritus University of ThraceAlexandroupolis 68100Greece Department of surgery Aristotle University of ThessalonikiThessaloniki 54636Greece

Probiotics are live microorganisms exerting beneficial effects on the host’s health when administered in adequate *** the most popular and adequately studied probiotics are bacteria from the families Lactobacillaceae,Bifidobacteriaceae and *** of them have been shown,both in vitro and in vivo studies of intestinal inflammation models,to provide favorable results by means of improving the gut microbiota composition,promoting the wound healing process and shaping the immunological *** intestinal conditions,such as inflammatory bowel diseases(IBD),are characterized by an imbalance in microbiota composition,with decreased diversity,and by relapsing and persisting inflammation,which may lead to mucosal *** the results of the clinical studies investigating the effect of probiotics on patients with IBD are still controversial,it is without doubt that these microorganisms and their metabolites,now named postbiotics,have a positive influence on both the host’s microbiota and the immune system,and ultimately alter the topical tissue *** influence is achieved through three axes:(1)By dis-placement of potential pathogens via competitive exclusion;(2)by offering protection to the host through the secretion of various defensive mediators;and(3)by supplying the host with essential *** will analyze and discuss almost all the in vitro and in vivo studies of the past 2 years dealing with the possible favorable effects of certain probiotic genus on gut immunological responses,highlighting which species are the most beneficial against intestinal inflammation.

关键词： Probiotics Lactobacillaceae Bifidobacteriaceae saccharomyces Intestinal inflammation Immune responses

Accuracy and precision of dried urine spot method for the detection of schistosoma mansoni circulating cathodic antigens in resource-limited settings

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Infectious Diseases of Poverty 2024年第1期13卷 103-104页

作者： Abdallah Zacharia Clemence Kinabo Twilumba Makene Huda Omary george Ogweno Faraja Lyamuya Billy Ngasala Muhimbili University of Health and Allied sciences Dar es Salaam Tanzania National Institute for Medical Research Mwanza Tanzania Neglected Tropical Diseases Control Program Ministry of Health Dodoma Tanzania

Background The World Health Organization recommends the use of schisto point-of-care circulating cathodic anti-gens(schisto POC-CCA)for screening of schistosoma mansoni as it offers better sensitivity than ***,there are limitation facing the use of this method including timely availability of the test *** aim of this study was to determine the reliability of dried urine spot(DUs)method for collection of urine and detection of *** using schisto POC-CCA cassettes in a resource-limited *** A cross-sectional study was conducted between October and November 2022 among 250 primary school children in sengerema District,northwestern *** CCA was detected in filter paper-based DUss,liquid urine using DUs schisto POC-CCA(index),and direct urine schisto POC-CCA(comparator)methods *** eggs in stool were detected using duplicate Kato-Katz(KK)*** measures of accuracy were com-puted and compared between the index and comparator *** strength of agreement between inter-raters precisions was tested using Cohen's kappa(k).Results This study revealed *** prevalence rates of 28.8%,54.0%and 50.8%by duplicate KK,direct urine schisto POC-CCA and DUs schisto POC-CCA methods *** mean intensity of infection among infected participants Was 86.3 eggs per gram of stool(EPG)ranging from 12.0 EPG to 824.0 *** sensitivity of DUs schisto POC-CCA and direct urine schisto POC-CCA Was 94.44%(95%CI:89.15-99.74%)and 97.22%(95%CI:93.43-100.00%)*** DUs schisto POC-CCA method had slightly higher specificity(66.85%)than direct urine schisto POC-CCA method(63.48%).The accuracy of the DUs schisto POC-CCA Was found to be slightly high(74.80%,95%CI:68.94-79.06%)compared to that of direct urine schisto POC-CCA(73.20%,95%CI:67.25-78.59%).There was good agreement between two laboratory technologists who performed the DUs schisto POC-CCA method on similar samples(k=0.80,95%CI:0.59-0.95).Con

关键词： Accuracy Point-of-care circulating cathodic antigen Dried urine spot schistosoma mansoni sensiti specificity

Dynamics of a Quantum Dissipative system Coupled with an Oscillator

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Journal of Applied Mathematics and Physics 2024年第4期12卷 1472-1491页

作者： Emmanouil george Thrapsaniotis Athens Greece

We study the dynamics of a quantum dissipative system. Besides its linear coupling with a harmonic bath modelling the dissipation, we suppose that it is coupled with an oscillator with an interaction of the form s 2 x 2 . In our study, we integrate over the bath and the oscillator, extract the corresponding influence functionals and then solve the system’s sign problem. We apply the theory to the case of a double well and study the time evolution of the expectation value of the position.

关键词： Double Well Harmonic Bath Oscillator Influence Functional sign solved Propagator Position

Hydrodynamic simulation of the Pagasitikos Gulf, Greece

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Computational Water, Energy, and Environmental Engineering 2024年第1期13卷 58-85页

作者： george Bousbouras Panagiotis Angelidis Division of Hydraulics Department of Civil Engineering School of Engineering Democritus University of Thrace Kimmeria Campus Xanthi Greece

semi-enclosed sea basins have difficulty in recharging their waters due to limited communication with larger water bodies, with understandable consequences for their environmental status. This paper aims at the computational simulation of the hydrodynamic characteristics of the waters of the Pagasitikos Gulf (Greece), which has limited communication and water exchange with the Aegean sea and is subject to intense environmental pressures The Estuary, Lake & Coastal Ocean 3d hydrodynamic Model (ELCOM 2.2) combined with its later version Aquatic Ecosystem Model-3d (AEM3D) were used for the simulation. The simulation included the topography of the area, the bay’s bottom geometry, atmospheric loadings, tides, the influence of the Coriolis force and boundary conditions. The hydrodynamic behaviour of the bay, water circulation, velocities at the surface and in depth, water recharge and residence time throughout the bay, density variation and other factors were examined to determine the impact of all these on the aquatic ecosystem.

关键词： Hydrodynamic simulation semi-Enclosed sea Basins Pagasitikos Gulf Greece

Thermochemical co-conversion of biomass-plastic waste to biochar:a review

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Green Chemical Engineering 2024年第1期5卷 31-49页

作者： Adewale george Adeniyi Kingsley O.Iwuozor Ebuka Chizitere Emenike Oluwaseun J.Ajala samuel Ogunniyi Kabir B.Muritala Department of Chemical Engineering Faculty of Engineering and TechnologyUniversity of IlorinIlorinP.M.B.1515Nigeria Department of Chemical Engineering Landmark UniversityOmu-AranKwara StateP.M.B.1001Nigeria Department of Pure and Industrial Chemistry Nnamdi Azikiwe UniversityAwkaP.M.B.5025Nigeria Department of Chemistry Federal University of TechnologyBosso CampusMinnaNiger StateP.M.B.65Nigeria

Biomass and plastics are two of the most common municipal solid wastes globally that have continuously placed a burden on the *** is therefore important that they are properly *** coconversion offers a valuable opportunity to recycle biomass and plastics simultaneously into biochar,which reduces the time and cost of recycling them individually while producing a material with a wide range of *** study is a review of published literature that discusses the thermochemical co-processing of biomass and plastic wastes into *** was observed that co-pyrolysis and co-hydrothermal carbonization are the most commonly utilized technologies for this *** characteristics of different biomass and plastics that have been thermochemically converted into biochar were *** properties of the resulting biochar are affected by the feedstock composition,pre-treatment and blending ratio,the reactor’s configuration,reaction temperature,and the presence of a *** studies found that treating the feedstocks separately resulted in a lower yield of biochar than processing them *** biochar created by this procedure has been used as a soil additive and as an adsorbent for water *** perspectives and suggestions,such as the necessity for some technical advancement,biochar’s economic benefits,improved government participation,and raised social awareness,were also *** factors have the potential to propel this field of study to great horizons.

关键词： Biomass Co-pyrolysis Plastic Thermochemical process Valorization

Chronic effects of stretching on range of motion with consideration of potential moderating variables:A systematic review with meta-analysis

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Journal of sport and Health science 2024年第2期13卷 186-194页

作者： Andreas Konrad shahab Alizadeh Abdolhamid Daneshjoo saman Hadjizadeh Anvar Andrew Graham Ali Zahiri Reza Goudini Chris Edwards Carina scharf David george Behm Institute of Human Movement science Sport and HealthGraz UniversityGraz A-8010Austria school of Human Kinetics and Recreation Memorial University of NewfoundlandSt.John’sNL A1C 5S7Canada Department of sport Injuries and Corrective Exercises Faculty of Sport SciencesShahid Bahonar University of KermanKerman 76169-13439Iran

Background:It is well known that stretch training can induce prolonged increases in joint range of motion(ROM).However,to date more information is needed regarding which training variables might have greater influence on improvements in ***,the purpose of this metaanalysis was to investigate the effects of stretch training on ROM in healthy participants by considering potential moderating variables,such as stretching technique,intensity,duration,frequency,and muscles stretched,as well as sex-specific,age-specific,and/or trained state-specific adaptations to stretch ***:We searched through PubMed,scopus,Web of science,and sportDiscus to find eligible studies and,finally,assessed the results from 77 studies and 186 effect sizes by applying a random-effect ***,by applying a mixed-effect model,we performed the respective subgroup *** find potential relationships between stretch duration or age and effect sizes,we performed a ***:We found a significant overall effect,indicating that stretch training can increase ROM with a moderate effect compared to the controls(effect size=-1.002;Z=-12.074;95%confidence interval:-1.165 to-0.840;psubgroup analysis showed a significant difference between the stretching techniques(p=0.01)indicating that proprioceptive neuromuscular facilitation and static stretching produced greater ROM than did ballistic/dynamic ***,there was a significant effect between the sexes(p=0.04),indicating that females showed higher gains in ROM compared to ***,further moderating analysis showed no significant relation or ***:When the goal is to maximize ROM in the long term,proprioceptive neuromuscular facilitation or static stretching,rather than ballistic/dynamic stretching,should be *** to consider in future research as well as sports practice is that neither volume,intensity,nor frequency of stretching were

关键词： Flexibility Long-term stretching stretch training

Deformations at Earth’s dayside magnetopause during quasi-radial IMF conditions:Global kinetic simulations and soft X-ray Imaging

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Earth and Planetary Physics 2024年第1期8卷 59-69页

作者： ZhongWei Yang RiKu Jarvinen XiaoCheng Guo TianRan sun Dimitra Koutroumpa george K.Parks Can Huang BinBin Tang QuanMing Lu Chi Wang state Key Laboratory of space Weather National Space Science CenterChinese Academy of SciencesBeijing 100190China Finnish Meteorological Institute FI-00101 HelsinkiFinland LATMOs/IPsL CNRSUVSQ UniversitéParis-SaclaySorbonne UniversitéGuyancourt78280France space sciences Laboratory University of CaliforniaBerkeleyCalifornia 94720USA CAs Engineering Laboratory for Deep Resources Equipment and Technology Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029 China Deep space Exploration Laboratory/school of Earth and space sciences University of Science and Technology of ChinaHefei 230026China

The solar wind Magnetosphere Ionosphere Link Explorer(sMILE)is a joint mission of the European space Agency(EsA)and the Chinese Academy of sciences(CAs).Primary goals are investigating the dynamic response of the Earth's magnetosphere to the solar wind(sW)impact via simultaneous in situ magnetosheath plasma and magnetic field measurements,X-Ray images of the magnetosheath and magnetic cusps,and UV images of global auroral *** deformations associated with magnetosheath high speed jets(HsJs)under a quasi-parallel interplanetary magnetic field condition are studied using a threedimensional(3-D)global hybrid *** X-ray intensity calculated based on both physical quantities of solar wind proton and oxygen ions is *** obtain key findings concerning deformations at the magnetopause:(1)Magnetopause deformations are highly coherent with the magnetosheath HsJs generated at the quasi-parallel region of the bow shock,(2)X-ray intensities estimated using solar wind h+and self-consistentO7+ions are consistent with each other,(3)Visual spacecraft are employed to check the discrimination ability for capturing magnetopause deformations on Lunar and polar orbits,*** sMILE spacecraft on the polar orbit could be expected to provide opportunities for capturing the global geometry of the magnetopause in the equatorial plane.A striking point is that sMILE has the potential to capture small-scale magnetopause deformations and magnetosheath transients,such as HsJs,at medium altitudes on its *** results also demonstrate that a lunar based imager(e.g.,Lunar Environment heliospheric X-ray Imager,LEXI)is expected to observe a localized brightening of the magnetosheath during HsJ events in the meridian *** preliminary results might contribute to the pre-studies for the sMILE and LEXI missions by providing qualitative and quantitative soft X-ray estimates of dayside kinetic processes.

关键词： collisionless shock sMILE mission foreshock