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In.ern.tion.l Journ.l of Geoscien.es 2013年第1期4卷 108-115页

作者： george n. jimmy Akpan.A. Otu Umoh A. Asuquo Departmen. of Physics Akwa Ibom State University Akwa Ibom Nigeria Departmen. of Physics University of Calaber Calaber Nigeria Departmen. of Physics University of Uyo Uyo Nigeria

This paper presen.s the first work of its kin. within.the con.in.s of the study area. It un.avels the distribution.of the layers of con.uctive san. an. their depths of in.eraction.between.freshwater from fresh san.s an. saltwater within.the con.uctive layers in.the coastal region.of Akwa Ibom State (n.geria) aroun. the Gulf of Guin.a. Vertical electrical soun.in. (VES) data whose fidelity was achieved by con.train.n. the data by the available n.arby logged borehole in.ormation.durin. in.erpretation.was the method applied. In.the western.region.of the study area, the ferrugin.zed an. salin. water layer is foun. within.the depth ran.e of 22 to 75 m deep. In.the n.rthern.zon., con.uctive san.y layer is foun. within.50 to 210 m an. in.the eastern.zon., the salin. an. ferrugin.zed san.y layer is foun. within.the depth of 88.5 m an. above. Gen.rally, the horizon.al an. vertical cross section. of the subsoil an. the flow regime from water table depths have been.delin.ated. With these in.ormation. water can.be tapped in.the area with caution.an. the flow direction.determin.d can.be used as in.ut parameter in.detailed con.amin.tion.study.

关键词： Freshwater Saltwater Ferrugin.zed an. Salin. San.s VES

Cerebral ven.us sin.s thrombosis:chan.in. tren.s in.the in.iden.e,age an. gen.er(fin.in.s from the CMC Vellore CVT registry)

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Stroke & Vascular n.urology 2024年第3期9卷 252-257页

作者： An.el Miraclin.T John.Davis Prasad george Abraham n.n.n.Mahasampath Gowri Deepti Bal Atif Iqbal Ahmed Shaikh Rohit n.Ben.amin.Appaswamy Thirumal Prabhakar Ajith Sivadasan.Vivek Mathew San.ith Aaron Departmen. of n.urological Scien.es Christian Medical CollegeVelloreTamil NaduIndia Departmen. of Biostatistics Christian Medical CollegeVelloreTamil NaduIndia

Backgroun. Multiple cerebral ven.us sin.s thrombosis(CVT)registries from various geographical region. in.icate that female gen.er,the use of con.raceptive pills,pregn.n.y an. puerperium are importan. risk *** this study,we report the chan.es in.the epidemiology of patien.s with CVT man.ged over the past 26 *** The CMC Vellore CVT registry is a prospectively main.ain.d database at the Christian.Medical College,Vellore sin.e Jan.ary *** software was used to an.lyse the data an. assess the chan.es in.the in.iden.e,age an. gen.er distribution.over the previous 26 *** Amon. 1701 patien.s treated durin. the study period,908(53%)were women.an. 793(47%)were *** mean.in.iden.e of CVT was 49 per 100000 admission. before 2010,which in.reased to 96 per 100000 after *** gen.er had a higher odds of developin. CVT OR–2.07(CI 1.68 to 2.55,pn.n. in.iden.e of postpartum CVT after 2010 compared with the decade before 2010(50%vs 20%).The mean.age at presen.ation.had in.reased from 24.5 to 33.2 years in.the last *** There was a clear chan.e in.the gen.er pattern.from bein. a con.ition.with female prepon.eran.e,to on. where equal or more men.are bein. *** in.iden.e of postpartum CVT cases could be the drivin. *** in.rease in.the overall in.iden.e of CVT cases was n.ted,probably due to a higher in.ex of clin.cal suspicion.an. better diagn.stic imagin. modalities.

关键词： CVT drivin. main.ain.d

A Comparative Study of Adomian.Decomposition.Method with Variation.l Iteration.Method for Solvin. Lin.ar an. n.n.in.ar Differen.ial Equation.

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Journ.l of Applied Mathematics an. Physics 2024年第8期12卷 2789-2819页

作者： Sarah Khaled Al Baghdadi n. Ameer Ahammad Gen.ral Studies Departmen. Technical and Vocational Training Corporation Tabuk KSA Departmen. of Mathematics Faculty of Science University of Tabuk Tabuk KSA

This study compares the Adomian.Decomposition.Method (ADM) an. the Variation.l Iteration.Method (VIM) for solvin. n.n.in.ar differen.ial equation. in.en.in.erin.. Differen.ial equation. are essen.ial for modelin. dyn.mic systems in.various disciplin.s, in.ludin. biological processes, heat tran.fer, an. con.rol systems. This study addresses first, secon., an. third-order n.n.in.ar differen.ial equation. usin. Mathematica for data gen.ration.an. graphin.. The ADM, developed by george Adomian. uses Adomian.polyn.mials to han.le n.n.in.ar terms, which can.be computation.lly in.en.ive. In.con.rast, VIM, developed by He, directly iterates the correction.fun.tion.l, providin. a more straightforward an. efficien. approach. This study highlights VIM’s rapid con.ergen.e an. effectiven.ss of VIM, particularly for n.n.in.ar problems, where it simplifies calculation. an. offers direct solution. without polyn.mial derivation. The results demon.trate VIM’s superior efficien.y an. rapid con.ergen.e of VIM compared with ADM. The VIM’s min.mal computation.l requiremen.s make it practical for real-time application. an. complex system modelin.. Our fin.in.s align.with those of previous research, con.irmin. VIM’s efficien.y of VIM in.various en.in.erin. application.. This study emphasizes the importan.e of selectin. appropriate methods based on.specific problem requiremen.s. While ADM is valuable for certain.n.n.in.arities, VIM’s approach is ideal for man. en.in.erin. scen.rios. Future research should explore broader application. an. hybrid methods to en.an.e the solution.s accuracy an. efficien.y. This comprehen.ive comparison.provides valuable guidan.e for selectin. effective n.merical methods for differen.ial equation. in.en.in.erin..

关键词： Differen.ial Equation. n.merical An.lysis Mathematical Computin. En.in.erin. Models n.n.in.ar Dyn.mics

Where Is the Chin.se Econ.my Headed in.2024?

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Beijin. Review 2024年第4期67卷 21-21页

作者： george n.Tzogopoulos the EU-Chin. Program at the Cen.re In.ern.tion.l de Formation.Europeen.e

The n.w year has started with on.oin. region.l *** con.licts in.Ukrain. an. the Middle East persist an. cause un.ertain.y in.the world *** Middle East crisis,in.particular,has already shown.some sign. of a spillover *... 详细信息

关键词： compan.es effect Middle

Boron.con.ain.n. compoun.s as labels,drugs,an. theran.stic agen.s for diabetes an. its complication.

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World Journ.l of Diabetes 2024年第6期15卷 1060-1069页

作者： Marvin.A Sorian.-Ursúa R Ivan.Cordova-Chávez Eun.ce D Farfan.García george Kabalka Departmen. of Physiology Escuela Superior de MedicinaInstituto Politécnico NacionalCiudad de México 11340Mexico Departmen. of Physiology Instituto Politécnico NacionalMexico City 11340Mexico Departmen. of Biochemistry Instituto Politécnico NacionalMexico City 11340Mexico Departmen. of Chemistry The University of TennesseeKnoxvilleTN 37996United States

Diabetes is a disease with a high global *** strategies have failed to limit the advan.emen. an. impact of the *** early diagn.sis an. treatmen. will require the developmen. of n.w *** this sen.e,boron.on.ain.n. compoun.s have been.reported as agen.s with the ability to reduce glycemia an. *** have also been.used for labelin. an. measurin. carbohydrates an. other molecules lin.ed to the in.tial stages of diabetes an. its *** addition.certain.boron.compoun.s bin. to molecules related to diabetes developmen. an. their biological activity in.the regulation.of elevated ***,it should be n.ted that some boron.compoun.s appear to exert ben.ficial effects on.diabetes complication. such as acceleratin. woun. healin. while amelioratin. pain.in.diabetic patien.s.

关键词： Boron Carbohydrates Metabolism Diabetes Boron.dipyrromethen.

Liver Characterization.of a Cohort of Alpha-1 An.itrypsin.Deficien.y Patien.s with an. without Lun. Disease

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Journ.l of Clin.cal an. Tran.lation.l Hepatology 2024年第10期12卷 845-856页

作者： n.weed Mohammad Regin. Oshin. Ton.jun.Gu Virgin.a Clark Jorge Lascan. n.ziheh Assarzadegan.george Marek Mark Bran.ly n.zli Khodayari Division.of Pulmon.ry Critical Care and Sleep MedicineCollege of MedicineUniversity of FloridaGainesvilleFLUSA In.erdisciplin.ry Cen.er for Biotechn.logy Research Bioinformatics CoreUniversity of FloridaGainesvilleFLUSA Division.of Gastroen.erology Hepatology and NutritionCollege of MedicineUniversity of FloridaGainesvilleFLUSA Division.of Pathology Immunologyand Laboratory MedicineCollege of MedicineUniversity of FloridaGainesvilleFLUSA Division.of Gastroen.erology an. Hepatology Mayo ClinicRochesterMNUSA

Backgroun. an. Aims:Alpha-1 an.itrypsin.deficien.y(AATD)is a gen.tic disorder characterized by the misfoldin. an. accumulation.of the mutan. varian. of alpha-1 an.itrypsin.AAT)within.hepatocytes,which limits its access to the circulation.an. exposes the lun.s to protease-mediated tissue *** results in.progressive liver disease secon.ary to AAT polymerization.an. accumulation.an. chron.c obstructive pulmon.ry disease(COPD)due to deficien. levels of AAT within.the *** goal was to characterize the un.que effects of COPD secon.ary to AATD on.liver disease an. gen. ***:A subcohort of AATD in.ividuals with COPD(n.33)an. AATD in.ividuals without COPD(n.14)were evaluated in.this study from our previously reported cross-section.l *** used immun.histochemistry to assess the AATD liver phen.type,an. Rn. sequen.in. to explore liver *** observed a distin.t tran.criptomic profile in.liver tissues from AATD in.ividuals with COPD compared to those ***:A total of 339 gen.s were differen.ially *** pathways related to fibrosis,extracellular matrix remodelin.,collagen.deposition.hepatocellular damage,an. in.lammation.were sign.fican.ly upregulated in.the livers of AATD in.ividuals with *** an.lysis also revealed higher levels of fibrosis an. hepatocellular damage in.these ***:Our data supports a relation.hip between.the developmen. of COPD an. liver disease in.AATD an. in.roduces gen.s an. pathways that may play a role in.AATD liver disease when.COPD is *** believe addressin. lun. impairmen. an. airway in.lammation.may be an.approach to man.gin. AATD-related liver disease.

关键词： Alpha-1 an.itrypsin.deficien.y Chron.c obstructive pulmon.ry disease Liver fibrosis Liver biopsy Liver histology Tran.criptomics

Gen.tic characteristics of H1n. in.luen.a virus outbreak in.Chin. in.early 2023

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Virologica Sin.ca 2024年第3期39卷 520-523页

作者： Xuan.uan.Li Zefen. Don. Jiamin. Li Chuan.an.Dou Deyu Tian.Zhen.hai Ma Wen.un.Liu george F.Gao Yuhai Bi College of Life Scien.e an. Techn.logy Xinjiang UniversityUrumchi830046China CAS Key Laboratory of Pathogen.Microbiology an. Immun.logy Institute of MicrobiologyCenter for Influenza Research and Early-warning(CASCIRE)CAS-TWAS Center of Excellence for Emerging Infectious Diseases(CEEID)Chinese Academy of SciencesBeijing100101China Suzhou Cen.er for Disease Con.rol an. Preven.ion Suzhou215004China Lafayette College EastonPA 18042USA Un.versity of Chin.se Academy of Scien.es Beijing100049China D.H.Chen.School of Un.versal Health Zhejiang UniversityHangzhou 310058China

Dear Editor,In.luen.a A virus(IAV)exhibits rapid mutability an. an.igen.c *** the 20th cen.ury,IAV has caused at least four pan.emics(Yan. et al.,2022).Presen.ly,season.l H_(3)n.(2)an. H1n. are the prevailin. human.adaptive IAV subvarian.s respon.ible for human.*** implemen.ation.of public health in.erven.ion. sin.e the commen.emen. of the COVID-19 pan.emic has effectively curtailed global in.luen.a circulation.Olsen.et al.,2021).Followin. the down.egulation.of the preven.ion.an. con.rol strategies again.t COVID-19,global in.luen.a activity is showin. a recovery.

关键词： in.luen.a preven.ion H1n.

Differen.ial Tran.cription.l Respon.es in.Corn.al an. Lun. Epithelial Cells to Season.l In.luen.a With Poten.ial Fun.tion.of LGALS9

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In.ectious Microbes & Diseases 2024年第3期6卷 141-151页

作者： Yan. Han.Tin. Zhan. Dan.Bai Chan.chen. Wu Beiwei Ye Jian.an. Zhou Yin.ze Zhao george F.Gao Jun.Liu n.tion.l Clin.cal Research Cen.er for Ocular Diseases Eye HospitalWenzhou Medical UniversityWenzhouChina State Key Laboratory of Ophthalmology Optometry and Visual ScienceEye HospitalWenzhou Medical UniversityWenzhouChina n.C Key Laboratory of Biosafety National Institute for Viral Disease Control and PreventionChinese Center for Disease Control and Prevention(China CDC)BeijingChina Collaborative In.ovation.Cen.re of Regen.rative Medicin. an. Medical BioResource Developmen. an. Application.Co-con.tructed by the Provin.e an. Min.stry Guangxi Medical UniversityNanningChina n.tion.l Key Laboratory of In.elligen. Trackin. an. Forecastin. for In.ectiousDiseases(n.TFID) National Institute for Viral Disease Control and PreventionChinese Center for Disease Control and PreventionBeijingChina CAS Key Laboratory of Pathogen.Microbiology an. Immun.logy Institute of MicrobiologyChinese Academy of SciencesBeijingChina

Season.l flu,primarily caused by in.luen.a A H1n. an. H3n. subtype viruses or in.luen.a B viruses,is the most prevalen. respiratory tract in.ection.globally an. leads to substan.ial morbidity an.mortality *** the in.luen.a virus bein. in.tially recogn.zed as a respiratory pathogen.ithwell-characterized tran.mission.through respiratory droplets,its impact on.the ocular epithelium an. associated gen. expression.remain. relatively *** this study,we in.estigated the tran.cription.l profiles of immortalized human.corn.al epithelial cells(HCE-S)an. A549 human.lun. epithelial cells in.ected with H1n. an. H3n. in.luen.a *** comparison.with A549 cells,a reduced n.mber of differen.ially expressed gen.swas observed in.HCE-S upon.in.luen.a virus ***,there was a sign.fican. upregulation.of the gen.s IFI44L an. OAS1,alon. with lower release of the CCL5/RAn.ES ***,our fin.in.s revealed un.quely upregulated LGALS9(en.odin. galectin.9)in.HCE-S followin. in.ection.with the 2009 pan.emic H1n. ***,targeted kn.ckdown.of LGALS9 in.these cells resulted in.a measurable decrease in.viral in.ection.highlightin. its role in.the cellular respon.es to in.luen.a virus an. suggestin. a n.vel aven.e for an.iviral ***,our fin.in.s provide in.ight in.o the distin.t mechan.sms of in.luen.a virus in.eraction. with differen. epithelial cells an. un.erscore the importan.e of studyin. the ocular surface in.un.erstan.in. in.luen.a pathogen.sis.

关键词： immortalized human.corn.al epithelial cell lin. human.pulmon.ry epithelial cell lin. in.luen.a A virus tran.criptome sequen.in. LGALS9

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DIPLOMATIC DECADES

Beijin. Review 2024年第20期67卷 20-20页

作者： george n.Tzogopoulos Cen.re In.ern.tion.l de Formation.Européen.e

This year marks the 6Oth an.iversary of Sin.-Fren.h diplomatic *** is n.t a typical *** back to 1964,it becomes eviden. that in.ern.tion.l con.ition. did n.t n.cessarily favor such a breakthrough at that time.

关键词： an.iversary breakthrough diplomatic

Chin.se n.w Year Lesson.

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Beijin. Review 2024年第6期67卷 24-24页

作者： george n.Tzogopoulos Cen.re In.ern.tion.l de Formation.Européen.e

The an.ien. Chin.se civilization.datin. back five millen.ia,remain. a poin. of referen.e an. a reason.for admiration.in.today's *** it makes sen.e that several Chin.se govern.en.al in.tiatives outlin. the lin. between.past an. *** Global Civilization. In.tiative,proposed by Presiden. Xi Jin.in. in.2023 an. mean. to promote human.ty's shared values,con.titutes on. characteristic example thereof.

关键词： datin. human.ty today