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Endoclipping treatment of life-threatening rectal bleeding after prostate biopsy

World Journal of Gastroenterology 2009年第9期15卷 1130-1133页

作者： Panagiotis Katsinelos Jannis Kountouras Georgios Dimitriadis Grigoris Chatzimavroudis Christos Zavos Ioannis Pilpilidis george Paroutoglou george germanidis Kostas Mimidis Department of Endoscopy and Motility Unit Central Hospital54635 ThessalonikiGreece Department of Gastroenterology Second Medical ClinicAristotle Universityof ThessalonikiIppokration Hospital54635 ThessalonikiGreece First Department of Urology Aristotle University of ThessalonikiCentral Hospital54635ThessalonikiGreece

Rectal bleeding is frequently seen in patients undergoing transrectal ultrasound(TRUS)-guided multiple biopsy of the prostate,but is usually mild and stops *** report what is believed to be the first case of life-threatening rectal bleeding following this procedure,which was successfully treated by endoscopic intervention through placement of three clips on the sites of *** case emphasizes endoscopic intervention associated with endoclipping as a safe and effective method to achieve hemostasis in massive rectal bleeding after prostate ***,current data on the complications of the TRUS-guided multiple biopsy of the prostate and the options for treating fulminant rectal bleeding, a consequence of this procedure,are described.

关键词： Prostate biopsy Complications Massive rectal bleeding Endoscopic treatment Endoclipping

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Postprandial response of bone turnover markers in patients with Crohn's disease

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World Journal of Gastroenterology 2014年第28期20卷 9534-9540页

作者： Ioannis Karatzoglou Maria P Yavropoulou Maria Pikilidou george germanidis Evangelos Akriviadis Alexra Papazisi Michael Daniilidis Pantelis Zebekakis John G Yovos 1^(st) Department of Internal Medicine AHEPA University HospitalAristotle University of Thessaloniki54636 Thessaloniki Greece Division of Endocrinology and Metabolism AHEPA University HospitalAristotle University of Thessaloniki54636 Thessaloniki Greece 4^(th) Department of Internal Medicine Hippokration General Hospital54642 Thessaloniki Greece Department of Nuclear Medicine AHEPA University HospitalAristotle University of ThessalonikiUniversity Hospital Aristotle University of Thessaloniki 54636Thessaloniki Greece

AIM:To investigate the postprandial response of bone turnover markers in patients with Crohn’s disease(CD).METHODS:Fifty nine patients with CD aged 38±14years,and 45 healthy individuals matched for age and body mass index were included in the *** participants underwent an oral glucose tolerance test(OGTT)after an overnight fast and serum levels of the bone resorption marker C-terminal crosslinking telopeptide of type?Ⅰ?collagen(CTX-Ⅰ)and the bone formation marker procollagen type?Ⅰ?N propeptide were *** of the disease was assessed by calculation of the Crohn’s disease activity index(CDAI).RESULTS:Serum CTX-I was significantly higher in patients compared to controls(CTX-I:453±21 pg/mL vs 365±25 pg/mL,P=0.008),and values were significantly correlated with the activity of the disease(r=0.435,P=0.001).Results from OGTT-induced suppression of CTX-I showed two different *** with more active disease(assessed as CDAI>150)had a more excessive suppression of CTX-I compared to controls(55%vs 43%P<0.001),while patients on remission(assessed as CDAI<150)demonstrated an attenuated CTX-I suppression(30%vs 43%P<0.001).In line with this,CTX-I suppression after oral glucose load was significantly correlated with the activity of the disease(r=0.913,P<0.001).CONCLUSION:The physiological skeletal response of postprandial suppression of bone resorption is maintained in patients with CD and is strongly dependent to the activity of the disease.

关键词： Crohn's disease Bone metabolism Postprandial bone resorption Oral glucose tolerance test C-terminal crosslinking telopeptide of type Ⅰ collagen

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