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Effect of obesity on perioperative outcomes after laparoscopic hepatectomy

作者： (英)杰弗里·帕克(geoffrey parker)

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Hepatoma Research 2016年第1期2卷 323-327页

作者： Seeyuen J.Lee Adam Hauch Erica Kane Christoper DuCoin Michael Darden geoffrey parker Emad Kandil Joseph F.Buell Departments of Surgery Louisiana State University School of MedicineNew OrleansLA 70112USA Departments of Surgery Tulane University School of MedicineNew OrleansLA 70112USA Department of Economics Tulane UniversityNew OrleansLA 70112USA Tuck School of Business Administration Dartmouth CollegeHanoverNH 03755USA

Aim:Laparoscopic hepatectomy is increasing in utilization,however the procedure has not been adequately examined in the obese *** study aims to analyze the effect of obesity on perioperative outcomes after laparoscopic ***:Retrospective analysis of 396 laparoscopic hepatectomies in normal[body mass index(BMI)<25],overweight(BMI≥25),obese(BMI≥30),and severely obese(BMI≥35)patients using multivariate regression models to determine the risk factors for post-operative ***:Normal BMI(n=78;20%),overweight(n=209;52%),obese(n=86;22%),and severely obese(n=23;6%).Demographics were similar except for a higher American Society of Anesthesiologists(ASA)score in the obese *** blood loss and operating time were greatest in the overweight group,while length of stay and complications were statistically similar between *** analysis identified that complications were associated with weight class,ASA score,blood loss,and resection;multivariate analysis revealed ASA and transfusion were best correlated with ***:Obese and overweight patients have similar complication profiles to normal BMI patients while severely obese patients have a higher incidence of complications that are primarily limited to Clavien-Dindo class I and II.

关键词： Liver resection laparoscopy obesity

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生成式人工智能的未来

商学院 2024年第4期 14-14页

作者： Atin Gupta geoffrey G.parker 麻省理工学院斯隆管理学院麻省理工学院

生成式人工智能的发展已经在数字世界中带来了巨大变革,它可以创建新颖且真实的内容,例如文本、图像、音乐、视频和代码。如今,它也正逐渐渗透到物理世界,为我们处理各种机器和机器人任务提供帮助。在牛津大学研究人员最近的一项研究中... 详细信息

生成式人工智能的发展已经在数字世界中带来了巨大变革,它可以创建新颖且真实的内容,例如文本、图像、音乐、视频和代码。如今,它也正逐渐渗透到物理世界,为我们处理各种机器和机器人任务提供帮助。在牛津大学研究人员最近的一项研究中,人工智能专家预测,未来十年内,高达40%的家务活将实现自动化。

关键词：人工智能牛津大学生成式机器人未来十年自动化巨大变革

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林冠研究网络的创立

AMBIO-人类环境杂志 1994年第7期 461-461页

作者： Nalini M.Nadkarni geoffrey parker 寒江 The Evergreen State College Lab I Olympia Smithsonian Environmental Research Center

森林冠层对维持森林生态系统的多样性和恢复能力,以及发挥森林生态系统的功能来说都是很重要的。由于有了巨型吊车等新的林中作业设备,人们对森林冠层的兴趣增加了,有关森林冠层的信息量也增加了,所以我们需要新的手段和分析方法管理、... 详细信息

森林冠层对维持森林生态系统的多样性和恢复能力,以及发挥森林生态系统的功能来说都是很重要的。由于有了巨型吊车等新的林中作业设备,人们对森林冠层的兴趣增加了,有关森林冠层的信息量也增加了,所以我们需要新的手段和分析方法管理、分析和对比来自不同研究项目的数据。冠层学家们将需要:①新类型的数据;②比以前多

关键词：林冠森林冠层 CRN

The functional properties of synapses made by regenerated axons across spinal cord lesion sites in lamprey

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Neural Regeneration Research 2022年第10期17卷 2272-2277页

作者： David parker Department of Physiology Developmentand NeuroscienceUniversity of CambridgeCambridgeUK

While the anatomical properties of regenerated axons across spinal cord lesion sites have been studied extensively,little is known of how the functional properties of regenerated synapses compared to those in unlesioned *** study aims to compare the properties of synapses made by regenerated axons with unlesioned axons using the lamprey,a model system for spinal injury research,in which functional locomotor recovery after spinal cord lesions is associated with axonal regeneration across the lesion *** synapses below the lesion site did not differ from synapses from unlesioned axons with respect to the amplitude and duration of single excitatory postsynaptic *** also showed the same activity-dependent depression over spike ***,regenerated synapses did differ from unlesioned synapses as the estimated number of synaptic vesicles was greater and there was evidence for increased postsynaptic quantal *** axons above the lesion site,the amplitude and duration of single synaptic inputs also did not differ significantly from unlesioned ***,in this case,there was evidence of a reduction in release probability and inputs facilitated rather than depressed over spike *** inputs from single regenerated axons below the lesion site thus do not increase in amplitude to compensate for the reduced number of descending axons after functional ***,the postsynaptic input was maintained at the unlesioned level using different synaptic ***,the facilitation from the same initial amplitude above the lesion site made the synaptic input over spike trains functionally *** may help to increase propriospinal activity across the lesion site to compensate for the lesion-induced reduction in supraspinal *** animal experiments were approved by the Animal Ethics Committee of Cambridge University.

关键词： electrophysiology lamprey plasticity regeneration reticulospinal axon spinal cord spinal injury synapse

Positron emission particle tracking——Application and labelling techniques

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Particuology 2008年第1期6卷 16-23页

作者： David J. parker School of Physics and Astronomy the University of Birmingham Edgbaston Birmingham B15 2TT UK

The positron emission particle tracking （PEPT） technique has been widely used in science and engineering to obtain detailed information on the motion and flow fields of fluids or granular materials in multiphase systems, for example, fluids in rock cracks, chemical reactors and food processors; dynamic behaviour of granular materials in chemical reactors, granulators, mixers, dryers, rotating kilns and ball mills. The information obtained by the PEPT technique can be used to optimise the design, operational conditions for a wide range of industrial process systems, and to evaluate modelling work. The technique is based on tracking radioactively labelled particles （up to three particles） by detecting the pairs of backto-back 511 keV γ-rays arising from annihilation of emitted positrons. It therefore involves a positron camera, location algorithms for calculating the tracer location and speed, and tracer labelling techniques. This paper will review the particle tracking technique from tracking algorithm, tracer labelling to their application.

关键词： PEPT Tracer Algorithm Tracking

A collaboration into research on nanoparticles (ACORN)

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Particuology 2009年第2期7卷 93-105页

作者： David G. parker Chemistry Innovation The HeathRuncorn WA7 4QXUnited Kingdom

This paper describes the operation and outcome of one of the United Kingdom＇s largest multi-partner research activities in nanoparticles. The research covers the discovery and development of organic and inorganic crystals/nanoparticles, nanoparticle properties towards specific product applications. The research also encompassed bespoke measurement technology for nanoparticles and structure interactions. Significant research outcomes are summarised. The paper illustrates the advantages from industrially motivated research and value of collective action between a broad group of researchers in a nation.

关键词： Nanoparticles Nanoparticle manufacture Nanocrystals Nanoassembly structure Modelling

Functional changes after spinal lesions: implications for interventions

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Neural Regeneration Research 2018年第5期13卷 811-812页

作者： David parker Department of Physiology Neuroscience and DevelopmentUniversity of Cambridge

We have known for many years that the spinal cord can generate some basic locomotor outputs under specific experimental conditions without any input from the brain or the periphery（Stuart and Hultborn,2008）.However,when inputs from the brain are lost following spinal cord injury（SCI）,the mammalian spinal cord is unable to generate normal,goal-directed locomotor outputs.

关键词： Functional changes after spinal lesions implications for interventions

The ethical cost of doing nothing

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National Science Review 2020年第7期7卷 1260-1262页

作者： Andrew J.parker University of Oxford Department of PhysiologyAnatomy and Genetics

Concern has been raised about the ethics and risks of performing genetic interventions in macaque monkeys to study models of human neuropsychiatric conditions. Here I point out that,when the outcome of some situations is truly uncertain, human decision makers tend to evaluate these situations inconsistently. The consequences of this inconsistency are sometimes profound, as they lead policy makers and reviewers to ignore or discount the ethical costs of doing nothing. I conclude that there are fundamental problems with the ‘precautionary

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Strong Laws of Large Numbers for Double Sums of Banach Space Valued Random Elements

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Acta Mathematica Sinica,English Series 2019年第5期35卷 583-596页

作者： Robert parker Andrew ROSALSKY Department of Biostatistics University of Florida Department of Statistics University of Florida

For a double array {V_(m,n), m ≥ 1, n ≥ 1} of independent, mean 0 random elements in a real separable Rademacher type p(1 ≤ p ≤ 2) Banach space and an increasing double array {b_(m,n), m ≥1, n ≥ 1} of positive constants, the limit law ■ and in L_p as m∨n→∞ is shown to hold if ■ This strong law of large numbers provides a complete characterization of Rademacher type p Banach spaces. Results of this form are also established when 0 < p ≤ 1 where no independence or mean 0 conditions are placed on the random elements and without any geometric conditions placed on the underlying Banach space.

关键词： Real separable Banach space double array of independent random elements strong law of large numbers almost sure convergence Rademacher type p Banach space convergence in Lp