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World Journal of Diabetes 2024年第6期15卷 1070-1073页

作者： Xiao-Tian Lei Dan-Lan Pu geng shan Qi-Nan Wu Department of Endocrinology The First Affiliated Hospital of the Third Military Medical University(Army Medical University)Chongqing 400038China Department of Endocrinology Chongqing Yubei District People's HospitalChongqing 400030China Department of Endocrinology Dazu Hospital of Chongqing Medical UniversityThe People's Hospital of DazuChongqing 402360China

In this editorial,we commented on the article published in the recent issue of the World Journal of *** cardiomyopathy(DCM)is characterized by myocardial fibrosis,ventricular hypertrophy and diastolic dysfunction in diabetic patients,which can cause heart failure and threaten the life of *** pathogenesis of DCM has not been fully clarified,and it may involve oxidative stress,inflammatory stimulation,apoptosis,and *** is lack of effective therapies for DCM in the clinical *** have been widely used in the clinical practice for years mainly to reduce cholesterol and stabilize arterial plaques,and exhibit definite cardiovascular protective *** have shown that statins also have anti-inflammatory and antioxidant *** were particularly concerned about the recent findings that atorvastatin alleviated myocardial fibrosis in db/db mice by regulating the antioxidant stress and antiinflammatory effects of macrophage polarization on diabetic myocardium,and thereby improving DCM.

关键词： Diabetic cardiomyopathy Statins Macrophage Oxidative stress

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食品理化检测实验室风险定量评价模型的构建

理化检验（化学分册） 2024年第2期60卷 227-233页

作者：单耕中国合格评定国家认可中心北京100062

食品理化检测实验室作为检验检测行业的重要组成部分,为企业产品的质量控制和国家监管政策的落地实施提供技术支撑,为社会大众和利益相关方提供可信的数据结果,在整个国家的食品安全监管体系中扮演着非常重要的角色。如果食品理化检测... 详细信息

食品理化检测实验室作为检验检测行业的重要组成部分,为企业产品的质量控制和国家监管政策的落地实施提供技术支撑,为社会大众和利益相关方提供可信的数据结果,在整个国家的食品安全监管体系中扮演着非常重要的角色。如果食品理化检测实验室的日常运作中出现未识别的重大风险,或者对已经识别的风险评价不准确,采取的应对措施不及时、不得当,不仅可能给实验室造成重大损失,还可能给客户带来严重负面影响,从而引发客户的投诉甚至追责[1]。

关键词：定量评价模型利益相关方重大风险理化检测实验室风险评价检验检测监管政策日常运作

论污染环境罪的罪过形式“包括过失”——层级罪过说之提倡

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中国地质大学学报（社会科学版） 2024年第2期24卷 19-31页

作者：苏永生史山庚河北大学法学院河北保定071000

在我国刑法理论界,关于污染环境罪的罪过形式主要有故意说、混合罪过说和择一罪过说。各种学说从不同角度对污染环境罪的罪过形式作出了较为合理的解释,但均存在不足。不论从刑法相关条文的客观含义还是污染环境罪的处罚必要性来看,均... 详细信息

在我国刑法理论界,关于污染环境罪的罪过形式主要有故意说、混合罪过说和择一罪过说。各种学说从不同角度对污染环境罪的罪过形式作出了较为合理的解释,但均存在不足。不论从刑法相关条文的客观含义还是污染环境罪的处罚必要性来看,均应当将污染环境罪的罪过形式解释为“包括过失”,而且过失与故意之间系层级关系,即故意是建立在过失基础之上的、更高层级的罪过形式。此种解释结论所引出的主要问题是,如何根据罪过形式的不同实现刑罚个别化,进而贯彻罪刑相适应和责任主义原则。为此,应当提倡根据故意从重处罚,即将故意的功能拓展到量刑领域。此解释结论可以运用于指导所有罪过形式“包括过失”之具体犯罪的量刑。

关键词：污染环境罪罪过形式 “包括过失” 根据故意从重处罚

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智能无人机在输电线路安全管理中的应用

集成电路应用 2024年第7期41卷 354-355页

作者：耿山国网河北省电力有限公司邯郸供电分公司河北056011

阐述智能无人机在电力巡检中的应用现状,探讨智能化无人机技术促进输电线路安全管理的实践策略,包括数据智能处理、无人机自主导航。采用智能无人机技术可提升电力系统安全管理能力。

关键词：智能无人机输电线路巡检数据处理自主导航

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浅谈集团化实验室质量管理及实验室认可方案

理化检验（化学分册） 2024年第6期60卷 616-619页

作者：张娜宋义运单耕武维伟李宏中国合格评定国家认可中心北京100062

集团化是现代企业发展的重要途径,能更好地发挥企业规模经营效益[1]。为了保证产品质量,保证企业产品的检测时效,集团化企业在各分公司建立实验室,并对各实验室制定统一的发展目标,统一管理,统一建立质量管理体系。为了更好地服务集团... 详细信息

集团化是现代企业发展的重要途径,能更好地发挥企业规模经营效益[1]。为了保证产品质量,保证企业产品的检测时效,集团化企业在各分公司建立实验室,并对各实验室制定统一的发展目标,统一管理,统一建立质量管理体系。为了更好地服务集团化实验室,采信集团的质量管理,减少重复性评审,中国合格评定国家认可委员会(以下简称“CNAS”)于2022年1月1日发布了CNAS-EL-21:2022《集团化企业内部实验室认可说明(试行)》[2],本工作从以下几个方面对集团化实验室质量体系建立和集团化实验室认可实施过程的相关问题进行探讨,为相关类型实验室提供参考。

关键词：集团化企业实验室质量管理实验室认可中国合格评定国家认可委员会产品质量

Effect of acid density of HZSM-5 on the oligomerization of ethylene in FCC dry gas

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Journal of Natural Gas Chemistry 2009年第2期18卷 156-160页

作者： Xue Ding shan geng Chunyi Li Chaohe Yang Guohui Wang State Key Laboratory of Heavy Oil Processing China University of Petroleum （East China） Qingdao 266555 Shandong China Daqing Refining ＆ Chemical Company CNPC Daqing 163411 Heilongjiang China

The oligomerization of ethylene in FCC dry gas over HZSM-5 catalyst with different Si/A12 ratios was studied. The effect of acid density of catalyst on the oligomerization of ethylene was discussed. By increasing the acid density of catalyst, ethylene conversion showed a linear increase, while the yields of olefins decreased when the acid density of catalyst exceeded 0.14mmolNH3/g owing to a promotion of hydrogen transfer reaction. Through comparing the average distance between acid sites on catalyst with kinetic diameters of olefins, it was found that the dimerization of ethylene was not restrained by the sparse distribution of acid sites, while the hydrogen transfer reaction of C3 and C4 olefins was limited. On these bases, a conclusion is proposed that the dimerization of ethylene proceeded via Eley-Rideal mechanism, while the hydrogen transfer reaction of C3 and C4 olefins followed the Langmuir-Hinshelwood mechanism.

关键词： ethylene oligomerization dry gas HZSM-5 mechanism

Growth factors induce the improved cardiac remodeling in autologous mesenchymal stem cell-implanted failing rat hearts

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2010年第4期11卷 238-248页

作者： Ze-wei TAO Long-gui LI Zhao-hua geng Tao DANG shan-jun ZHU Department of Cardiovascular Diseases Xinqiao Hospital Third Military Medical University Chongqing 40003 7 China

Therapeutically delivered mesenchymal stem cells (MSCs) improve ventricular remodeling. However,the mechanism underlying MSC cardiac remodeling has not been clearly determined. Congestive heart failure (CHF) was induced in rats by cauterization of the left ventricular free wall. MSCs were cultured from autologous bone marrow and injected into the border zone and the remote myocardium 5 d after injury. Ten weeks later,when compared with sham operation,CHF significantly increased nucleus mitotic index,capillary density,and expression of insulin-like growth factor 1,hepatocyte growth factor and vascular endothelial growth factor in the border zone (P<0.01) and decreased each of them in the remote myocardium (P<0.05 or P<0.01). MSC implantation in CHF dramatically elevated ex-pression of these growth factors in the remote myocardium and further elevated their expression in the border zone when compared with CHF without MSC addition (P<0.05 or P<0.01). This was paralleled by a higher nucleus mitotic index and a significantly increased capillary density both in the remote myocardium and in the border zone,and by a lower percentage of area of collagen and a higher percentage of area of myocardium in the border zone (P<0.05 or P<0.01),and cardiac remodeling markedly improved. Autologous MSC implantation promoted expression of growth factors in rat failing myocardium,which might enhance cardiomyogenesis and angiogenesis,and improved cardiac remodeling.

关键词： Mesenchymal stem cells Growth factor Myocardium Cardiac remodeling

Recyclable hydrolyzed polymers of intrinsic microporosity-1/Fe_(3)O_(4) magnetic composites as adsorbents for selective cationic dye adsorption

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Frontiers of Chemical Science and Engineering 2024年第2期18卷 113-125页

作者： Feng Zhang Shuainan Xu Xiumei geng Meixia shan Yatao Zhang School of Chemical Engineering Zhengzhou UniversityZhengzhou 450001China

Polymers of intrinsic microporosity shows great potential for dye adsorption and magnetic Fe_(3)O_(4) are easy to be *** this work,hydrolyzed polymers of intrinsic microporosity-1/Fe_(3)O_(4) composite adsorbents were prepared by phase inversion and hydrolysis process for cationic dye *** chemical structure and morphology of the composite adsorbents were systematically characterized by several characterization *** methylene blue as the target dye,the influences of solution pH,contact time,initial dye concentration,and system temperature on the methylene blue adsorption process were *** incorporation of Fe_(3)O_(4) particle into hydrolyzed polymers of intrinsic microporosity-1 endow the adsorbent with high magnetic saturation(20.7 emu·g^(–1))which allows the rapid separation of the ***,the adsorption process was simulated by adsorption kinetics,isotherms and thermodynamics to gain insight onto the intrinsic adsorption *** addition,the composite adsorbents are able to selectively adsorb cationic dyes from mixed dyes *** polymers of intrinsic microporosity/Fe_(3)O_(4) shows only a slight decrease for methylene blue adsorption after 10 adsorption/regeneration cycles,demonstrating the outstanding regeneration *** high adsorption capacity,outstanding regeneration ability,together with simple preparation method,endow the composite adsorbents great potential for selective removal of cationic dyes in wastewater system.

关键词： polymers of intrinsic microporosity magnetic adsorbent cationic dye adsorption

The inverse association between eGFR and depression in patients with coronary artery disease: A cross-sectional study

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South China Journal of Cardiology 2024年第1期25卷 1-10页

作者：程诗尧刘安邦孔博马欢刘全俊姜成尹晗郭兰耿庆山 Department of Cardiology Guangdong Provincial Peo-ple’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical University Guangzhou 510080China

Background The relationship between estimated glomerular filtration rate(e GFR)and depression in patients with coronary artery disease(CAD)remained *** A total of 561 patients with CAD were selected from Department of Cardiology between October 2017 and February 2018 while their depression status was evaluated by Patient Health Questionnaire-9(PHQ-9).The e GFR levels were compared between patients with and without depression and the link between e GFR and depression in CAD patients was *** Among 561CAD patients,63 patients(11.23%)were diagnosed with comorbid depression(PHQ-9≥10).The depression group presented significantly lower e GFR level than the non-depression *** fully-adjusted multivariate analysis,higher e GFR level was proved to be a protective factor for depression in CAD patients,reducing a 22%risk of depression for every 10 m L/(min·1.73 m2)increase of e GFR level(OR:0.78,95%CI:0.66-0.93).Similar results were found in the stratified analyses of both e GFR quartiles and chronic kidney disease(CKD)stages(P for trend0.05).A negative linear association was estimated between e GFR level and depression in CAD *** Our results suggested lower e GFR level in CAD patients with comorbid depression,displaying a negative linear correlation between e GFR and risk of depression in CAD *** findings implied that screening depression in CAD patients with decreased e GFR level or concomitant CKD should be highlighted in clinical practice.[S Chin J Cardiol 2024;25(1):1-10]

关键词： Estimated glomerular filtration rate Chronic kidney disease Depression Coronary artery disease Comorbidity

脑脉利颗粒联合依达拉奉右莰醇注射用浓溶液对急性脑梗死患者神经功能、血液流变学和氧化应激的影响

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现代生物医学进展 2024年第6期24卷 1077-1081页

作者：王婷耿闪张俐可欣胡楠黄海涛南京市中心医院药学部江苏南京210000 南京市中心医院神经内科江苏南京210000 常州市第一人民医院药学部江苏常州213000

目的:探讨脑脉利颗粒联合依达拉奉右莰醇注射用浓溶液对急性脑梗死(ACI)患者神经功能、血液流变学和氧化应激的影响。方法:选取南京市中心医院及常州市第一人民医院在2022年7月-2023年7月收治的ACI患者140例,根据随机数字表法将患者分... 详细信息

目的:探讨脑脉利颗粒联合依达拉奉右莰醇注射用浓溶液对急性脑梗死(ACI)患者神经功能、血液流变学和氧化应激的影响。方法:选取南京市中心医院及常州市第一人民医院在2022年7月-2023年7月收治的ACI患者140例,根据随机数字表法将患者分为对照组(n=70,常规治疗联合依达拉奉右莰醇注射用浓溶液治疗)和观察组(n=70,对照组基础上接受脑脉利颗粒治疗)。对比两组疗效、神经功能、日常生活活动能力、血液流变学和氧化应激变化情况。结果:观察组的临床总有效率较对照组更高(P<0.05)。观察组治疗后美国国立卫生研究院卒中量表(NIHSS)、血浆黏度、全血低切黏度、全血高切黏度、红细胞压积、丙二醛(MDA)低于对照组,日常生活能力量表评分(Barthel指数)评分、超氧化物歧化酶(SOD)高于对照组(P<0.05)。结论:脑脉利颗粒联合依达拉奉右莰醇注射用浓溶液治疗ACI患者,有助于调节血液流变学,改善患者的神经功能,减轻氧化应激,提高其日常生活活动能力。

关键词：脑脉利颗粒依达拉奉右莰醇注射用浓溶液急性脑梗死神经功能血液流变学氧化应激