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Effects of the Treatment of Carpal Tunnel Syndrome with Surgery and Injections on the Hospital Anxiety and depression Scale (HADS)

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Open Journal of Psychiatry 2023年第1期13卷 15-26页

作者： Domingo Ly-Pen José Luis Andreu gema de blas Isabel Millán Alberto Sánchez-Olaso Cootehill Medical Centre Cootehill Co. Cavan Ireland department of Rheumatology University Hospital Puerta de Hierro Majadahonda Madrid Spain Neurophysiology department University Hospital “Ramón y Cajal” Madrid Spain Biostatistics department University Hospital Puerta de Hierro Majadahonda Madrid Spain department of Plastic Surgery University Hospital “Ramón y Cajal” Madrid Spain

Background: The prevalence of carpal tunnel syndrome (CTS) and of anxiety and depression in primary care practice are high. Different studies had shown an increased prevalence of anxiety and depression in CTS patients. Nevertheless, few papers had been published studying the anxiety and depression scales in the treatment of CTS, either with corticosteroid injections (I) or with surgical decompression (S). Objective: To assess whether clinical improvement observed after the treatment of CTS either with I or with S correlates with an improvement in the punctuations of the Hospital Anxiety and depression scales (HADS), at 3, 6 and 12-month follow-up. Methods: Randomized and open-label clinical trial, comparing I and S. Patients with symptoms suggestive of CTS (nocturnal paraesthesias) of at least 3 months duration and neurophysiological confirmation were included. Patients with clinically apparent motor impairment were excluded. The subjective evaluation of symptoms was carried out using the visual-analogue scale of pain (VAS-p). Clinical reviews were performed 3, 6 and 12 months after treatment. Each patient completed the HADS questionnaire and a VAS-p at 0, 3, 6, and 12 months. Statistical significance was established using the Student’s t test and the Mann-Whitney U test when necessary. A linear regression analysis was used to know the effect of the treatment adjusted for the initial score of both scales. Results: 65 patients were included (30 in group I and 35 in group S). There was no statistical difference between both groups in terms of age, gender distribution, disease duration, VAS-p, neurophysiological testing severity of CTS or the 8 subscales of HADS. Both groups improved significantly in relation to the baseline VAS-p values, in the reviews at 3, 6 and 12 months, with no significant differences between I and S. At 6 months, the reduction in the anxiety scale was around 3 points for both treatments (S = 3.6 and I = 3.2), without reaching significant differe

关键词： Carpal Tunnel Syndrome Anxiety depression Local Corticosteroid Injections Surgery Hospital Anxiety and depression Scales (HADS)

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为维持高油价 OPEC+推迟增产

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商业周刊（中文版） 2024年第15期 32-33页

作者： Javier blas 程玺(译) 不详

欧佩克+(OPEC+)就像茶包,用热水才能冲开。已故的罗伯特·马布罗(Robert Mabro)作为石油市场的敏锐观察家,总是说这个组织只有面临长期的财务压力时才会采取真正的行动。从最近的举措看,OPEC+似乎仍未察觉到自己已身处加热的水壶之中。

关键词：石油市场财务压力 OPEC 欧佩克高油价

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Comment on "Vortex of Fluid Field as Viewed from Curvature" [Commun. Theor. Phys. 43 (2005) 604]

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Communications in Theoretical Physics 2010年第1期53卷 43-44页

作者： blas Herrera Gerard Fortuny departament d'Enginyeria Informàtica i Matemàtiques Universitat Rovira i Virgili

Here, we make comments to the conclusions of the paper： LIU Shi-Da, Sill Shao-Ying, LIU Shi-Kuo, et al., ＂Vortex of Fluid Field as Viewed from Curvature＂ [Commun. Theor. Phys. 43 （2005） 604].

关键词： curvature vortex

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Invasive strategy in elderly patients with acute coronary syndrome in 2018: close to the truth?

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Journal of Geriatric Cardiology 2019年第2期16卷 114-120页

作者： Sergio García-blas Clara Bonanad Juan Sanchis Servei de Cardiologia Hospital Clínic Universitari de València INCLIVA Universitat de ValènciaCIBERCV

Elderly population constitutes an increasingly larger proportion of patients admitted for acute coronary syndromes(ACS).The optimal management of ACS in these patients is still a challenge due to their clinical peculiarities and the paucity of specific data,and they have been traditionally managed more conservatively mainly based on subjective *** ST^segment elevation acute myocardial infarction urgent reperfusion is the standard of care and there is no upper age *** non-ST segment elevation acute myocardial infarction evidence is controversial,incomplete and mainly focused on chronological *** a strict conservative strategy should be avoided,routine invasive strategy may reduce the occurrence of myocardial infarction and need for revascularization at follow-up with no established benefit in terms of *** characteristics associated with aging,such as comorbidities and frailty,further discriminate patient's risk beyond *** is scarce,but it suggests that these features may modulate the benefit of invasive strategy in this *** trials should clarify the optimal management of ACS based on these parameters.

关键词： Acute coronary syndromes Comorbidity Frailty Percutaneous coronary intervention The elderly

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Distortion-stabilized ordered structures in A_(2)BB’O_(7) mixed pyrochlores

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npj Computational Materials 2019年第1期5卷 1076-1084页

作者： Ghanshyam Pilania Brian Puchala blas P.Uberuaga Materials Science and Technology Division Los Alamos National LaboratoryLos AlamosNM 87545USA Materials Science and Engineering department University of MichiganAnn ArborMI 48109USA

Pyrochlore oxides(A2B2O7)are interesting for a number of technological applications,including radiation damage tolerance and as ionic *** pyrochlores—containing two A and/or two B site cations—provide even more flexibility for tailoring properties owing to the diverse chemical and configurational degrees of freedom accessible within this chemical ***,we examine relative stability of different cation orderings in one model double pyrochlore Gd2(Zr_(x)Ti_(1−x))_(2)O_(7),as a function of Zr content *** results show that,in the presence of some very specific local cation arrangements,certain cation-ordered compositions in this system are highly stabilized as a result of large oxygen relaxation displacements,leading to the formation of an ordered‘double’pyrochlore *** origins of these anomalous oxygen relaxations are traced back to both the local cation symmetry and a strong chemical preference of Zr atoms towards adopting a 7-fold coordination environment,as opposed to a 6-fold coordination available in a regular pyrochlore ***,we examine the stability of this type of ordering in 131 other pyrochlore *** of our findings are discussed in relation to the observed composition-dependent ionic conductivity in these systems and connections with previously reported experimental findings are made.

关键词： structure ordered stabilized

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Architecture as device:Estrangement theory from literature to architecture

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Frontiers of Architectural Research 2022年第1期11卷 1-12页

作者： Qirui Wan Sergio Martín blas department of Architectural design ETSAMUniversidad Politécnica de MadridMadrid28040Spain

What is the estrangement of architecture?The concept has been incessantly mentioned by academics while there seems to be a lack of discussion systematically sorting out the significance,influence,and origins of estrangement asanarchitectural *** aims to discern the meaning of estrangement from the beginning and its process of entering the field of *** first part is expected to answer the following questions:what is estrangement’s original meaning in the field of literature and its variantions?The second part determines what estrangement is in architecture and in what form estrangement is represented according to these *** third part points out the difference during this translation fromliterature to architecture and demonstrates the reasonable inference thatmay actually compose the possibleway of applying the estranging technique in architecture.

关键词： Estrangement Architectural strategy Literature concept decontextualization Anthropopathic architecture

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The opening of maitotoxin-sensitive calcium channels induces the acrosome reaction in human spermatozoa： differences from the zona pellucida

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Asian Journal of Andrology 2011年第1期13卷 159-165页

作者： lulio C Chaivez Gerardo A de blas Josd L de la Vega-Beltran Takuya Nishigaki Mayel Chirinos Maria Elena Gonzaez-Gonzalez Fernando Larrea Alejandra Soiis Alberto Darszon Claudia L Trevino department of developmental Genetics and Molecular Physiology Biotechnology Institute UNAM Cuernavaca Mexico department of Reproduction Biology National Institute of Medical Sciences and Nutrition ＇Salvador Zubiran＇ Mexico City Mexico

The acrosome reaction （AR）, an absolute requirement for spermatozoa and egg fusion, requires the influx of Ca2＋ into the spermatozoa through voltage-dependent Ca2＋ channels and store-operated channels. Maitotoxin （MTx）, a Ca2＋-mobilizing agent, has been shown to be a potent inducer of the mouse sperm AR, with a pharmacology similar to that of the zona pellucida （ZP）, possibly suggesting a common pathway for both inducers. Using recombinant human ZP3 （rhZP3）, mouse ZP and two MTx channel blockers （U73122 and U73343）, we investigated and compared the MTx- and ZP-induced ARs in human and mouse spermatozoa. Herein, we report that MTx induced AR and elevated intracellular Ca2＋（[Ca2＋]~） in human spermatozoa, both of which were blocked by U73122 and U73343. These two compounds also inhibited the MTx-induced AR in mouse spermatozoa. In disagreement with our previous proposal, the AR triggered by rhZP3 or mouse ZP was not blocked by U73343, indicating that in human and mouse spermatozoa, the AR induction by the physiological ligands or by MTx occurred through distinct pathways. U73122, but not U73343 （inactive analogue）, can block phospholipase C （PLC）. Another PLC inhibitor, edelfosine, also blocked the rhZP3- and ZP-induced ARs. These findings confirmed the participation of a PLC-dependent signalling pathway in human and mouse zona protein-induced AR. Notably, edelfosine also inhibited the MTx-induced mouse sperm AR but not that of the human, suggesting that toxin-induced AR is PLC-dependent in mice and PLC-independent in humans.

关键词： acrosome reaction calcium channels human sperm maitotoxin mouse sperm

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The coppice-with-standards silvicultural system as applied to Eucalyptus plantations-a review

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Journal of Forestry Research 2014年第2期25卷 237-248页

作者： Antonio Carlos FERRAZ FILHO José Roberto Soares SCOLFORO blas MOLA-YUdeGO departamento de Ciências Florestais Universidade Federal de Lavras (UFLA) School of Forest Sciences University of Eastern Finland (UEF)

We review the management of Eucalyptus species under a coppice-with-standards （CWS） silvicultural system. CWS management results in product diversification, permitting production of small and large scale timber from the same stand. Eucalyptus species are suitable candidates for CWS management because： there are large worldwide plantation areas, sprouting capacity is high, and eucalypts are multipur- pose species. We discuss （1） short rotation Eucalyptus coppice manage- ment for energy and pulping and （2） Eucalyptus seedling management for solid wood products. We review the literature and discuss experi- ences with Eucalyptus managed under the CWS system. We also assess projects dealing with Eucalyptus coppice management, stand density regulation, pruning, and stand and wood quality. The growth environ- ment of the standard trees （heavy competition up to the first harvest, free growth afterwards） coupled with long rotations （〉20 years） results in high quality logs for solid wood products. Early pruning should be ap- plied to enhance wood quality. We propose a system for the silvicultural management of Eucalyptus under the CWS system, elaborating on the consequences of initial planting density, site productivity, and standard tree densities as well as timing of basic silvicultural applications.

关键词： stand density regulation coppice management pruning silvicultural system stand production diversification CWS

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Ischemic stroke:complication of hypertension in hospital west of Almeria in Spain

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Family Medicine and Community Health 2013年第1期1卷 8-13页

作者： JV GOMEZ-GONZALEZ blas GIL-EXTREMERA Critical Care Unit and Emergency department Poniente HospitalAlmeriaSpain Hypertension and Lipid Unit Service of Internal MedicineSan Cecilio University HospitalGranadaSpain

Objective:The aim of this paper was to analyse the etiologic,clinical,and therapeutic characteristics of the ischemic stroke in the comarca of Poniente,Almeria,***:An observational descriptive study was carried out from June 2005 to June 2006 in the Hospital of *** studied 243 patients admitted to Internal Medicine department diag-nosed with ischemic *** revised the clinical histories of patients using social,demographic,clinical,diagnostic,and therapeutic variables.A descriptive analysis of the variables was performed using SPSS V10.1 ***:A total of 172 patients(70.7%)were admitted to *** time course of the stroke episode was less than 6 hours(40.6%);mean age of patients 73 years(50% males);94% were autochthonous workers,6% immigrants,72% hypertensive,and 35% had a history of previous *** most common symptom was dysarthria(59%);brain CAT scan was performed in all of them within 6 hours after stroke onset,and antiplatelet drugs were given within 48 hours after stroke *** 30% of the patients received early rehabilitation,12% died within the first ***:We found clinical and epidemiologic characteristics similar to those reported in the literature;we found a lower incidence of CVD and a higher time course than the national average.

关键词： Hypertension Stroke Symptoms Risk factors

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Highly efficient multi-metal catalysts for carbon dioxide reduction prepared from atomically sequenced metal organic frameworks

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Nano Research 2021年第2期14卷 493-500页

作者： Celia Castillo-blas Consuelo Alvarez-Galvan Ines Puente-Orench Alba Garcia-Sanchez Freddy E.Oropeza Enrique Gutirrez-Puebla Angeles Monge Victor A.de la Pena-O'hea Felipe Gandara Materials Science Institute of Madrid(CSIC) C/Sor Juana Ines de la Cruz 3Madrid 28049Spain Instituto de Catalisis y Petroleoquimica(CSIC) dM arie Curie 2Madrid 28049Spain Instituto de Ciencia de Materiales de Aragon Pedro Cerbuna 12Zaragoza 50009Spain Institut Laue Langevin 71 Avenue des Martyrs38042 GrenobleFrance Photoactivated Processes Unit IMdeA Energy Institute Mostoles Technology ParkAvenida Ramdn de la Sagra 3MostolesMadrid 28935Spain department of Inorganic Chemistry University Autonomous of MadridC/Frandsco Tomdsy Valiente 7Madrid 28049Spain

The precise control on the combination of multiple metal atoms in the structure of metal-organic frameworks(MOFs)endowed by reticular chemistry,allows the obtaining of materials with compositions that are programmed for achieving enhanced *** present work illustrates how through the transformation of MOFs with desired arrangements of metal cations,multi-metal spinel oxides with precise compositions can be obtained,and used as catalyst precursor for the reverse water-gas shift *** differences in the spinel initial composition and structure,determined by neutron powder diffraction,influence the overall catalytic activity with changes in the process of in s itu formation of active,metal-oxide supported metal nanoparticles,which have been monitored and characterized with in situ X-ray diffraction and photoelectron spectroscopy studies.

关键词： reticular chemistry multi-metal metal-organic frameworks(MOFs) carbon dioxide reduction heterogeneous catalysis reverse water-gas shift in-situ X-ray photoelectron spectroscopy(XPS)

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