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Degradation of 3D-printed magnesium phosphate ceramics in vitro and a prognosis on their bone regeneration potential

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Bioactive Materials 2023年第1期19卷 376-391页

作者： gefel eugen Moseke Claus Schmitt Anna-Maria Dümmler Niklas Stahlhut Philipp Ewald Andrea Meyer-Lindenberg Andrea Vorndran Elke Institute and Department for Functional Materials in Medicine and Dentistry University Clinic WuerzburgWuerzburgGermany Institute for Biomedical Engineering(IBMT) University of Applied Sciences Mittelhessen(THM)Wiesenstraße 14GießenGermany Clinic for Small Animal Surgery and Reproduction Ludwig-Maximilians-UniversitätMunichGermany

Regenerative bone implants promote new bone formation and ideally degrade simultaneously to *** clinically established calcium phosphate bone grafts provide excellent osseointegration and osteoconductive efficacy,they are limited in terms of *** phosphate(MP)based ceramics are a promising alternative,because they are biocompatible,mechanically extremely stable,and degrade much faster than calcium phosphates under physiological *** of an implant material can include both chemical dissolution as well as cellular *** investigated the bioresorption of 3D powder printed struvite and newberyite based MP ceramics in vitro by a direct human osteoclast culture *** osteoclast response and cellular resorption was evaluated by means of fluorescence and TRAP staining,determination of osteoclast activities(CA II and TRAP),SEM imaging as well as by quantification of the ion release during cell ***,the bioactivity of the materials was investigated via SBF immersion,whereas hydroxyapatite precipitates were analyzed by SEM and EDX *** bioactive coating was resorbed by *** contrast,only chemical dissolution contributed to bioresorption of MP,while no cellular resorption of the materials was *** on our results,we expect an increased bone regeneration effect of MP compared to calcium phosphate based bone grafts and complete chemical degradation within a maximum of 1.5-3.1 years.

关键词： Newberyite Struvite Bioresorption Ceramic bone implants Human osteoclasts Bioactivity

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Corrigendum to“Degradation of 3D-printed magnesium phosphate ceramics in vitro and a prognosis on their bone regeneration potential”[***.19(2023)376-391/22]

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Bioactive Materials 2023年第2期20卷 41-41页

作者： eugen gefel Claus Moseke Anna-Maria Schmitt Niklas Dümmler Philipp Stahlhut Andrea Ewald Andrea Meyer-Lindenberg Elke Vorndran Institute and Department for Functional Materials in Medicine and Dentistry University Clinic WuerzburgWuerzburgGermany Institute for Biomedical Engineering(IBMT) University of Applied Sciences Mittelhessen(THM)Wiesenstraße 14GießenGermany Clinic for Small Animal Surgery and Reproduction Ludwig-Maximilians-UniversitätMunichGermany

The authors regret the reversal of the order of first and last names in the original *** correct order of the authors’first and last names are eugen gefel,Claus Moseke,Anna-Maria Schmitt,Niklas Dümmler,Philipp Stahl... 详细信息

关键词： ceramics magnesium potential

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