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Seaweed nutraceuticals and their therapeutic role in disease prevention

Food Science and Human Wellness 2019年第3期8卷 252-263页

作者： Abirami R.Ganesan Uma Tiwari gaurav rajauria School of Applied Sciences College of EngineeringScience and TechnologyFiji National UniversityFiji School of Science Institute of Technology SligoBallinodeCo.SligoIreland School of Agriculture and Food Science University College DublinLyons Research FarmCelbridgeCo.KildareIreland

There is a growing interest that bioactive compounds from seaweed can play a major therapeutic role in disease prevention in *** bioactives including polysaccharides,pigments,fatty acids,polyphenols and peptides have been proven to possess various beneficial biological properties that could potentially contribute to functional food and nutraceutical *** bioactive are explored for functional properties such as antioxidant,antibacterial,anticancer,antidiabetic,antitumor,antiviral,anti-inflammatory and anticoagulant properties,both in an in-vitro and in-vivo model *** review critically examines the existing scientific knowledge on primary and secondary metabolites from seaweed and their functional properties for health-related *** presents an update on the most recent evidence relating to their effect on health-related conditions and their action on cellular *** advancement and challenges for seaweed bioactive as a nutraceutical in relation to their biocompatibility and bioavailability to understand their therapeutic development is discussed.

关键词： Functional ingredients Glucose metabolism Lipid metabolism Macroalgae Bioavailability

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Potential of a fucoidan-rich Ascophyllum nodosum extract to reduce Salmonella shedding and improve gastrointestinal health in weaned pigs naturally infected with Salmonella

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Journal of Animal Science and Biotechnology 2022年第4期13卷 1193-1208页

作者： Brigkita Venardou John VO’Doherty Shane Maher Marion TRyan Vivian Gath Rajeev Ravindran Claire Kiely gaurav rajauria Marco Garcia-Vaquero Torres Sweeney School of Veterinary Medicine University College DublinBelfield Dublin 4Ireland School of Agriculture and Food Science University College DublinBelfield Dublin 4Ireland.

Background:Dietary supplementation with a fucoidan-rich Ascophyllum nodosum extract(ANE),possessing an in vitro anti-Salmonella Typhimurium activity could be a promising on-farm strategy to control Salmonella infection in *** objectives of this study were to:1)evaluate the *** activity of ANE(containing 46.6%fucoidan,18.6%laminarin,10.7%mannitol,4.6%alginate)in vitro,and;2)compare the effects of dietary supplementation with ANE and Zinc oxide(ZnO)on growth performance,Salmonella shedding and selected gut parameters in naturally infected *** was established post-weaning(newly weaned pig experiment)and following regrouping of post-weaned pigs and experimental re-infection with ***(challenge experiment).Results:In the in vitro assay,increasing ANE concentrations led to a linear reduction in *** counts(P0.05).ANE supplementation decreased the Enterobacteriaceae counts compared to the *** counts were also reduced in the ZnO-residual group compared to the control(P<0.05).ANE supplementation decreased the expression of interleukin 22 and transforming growth factor beta 1 in the ileum compared to the control(P<0.05).Conclusions:ANE supplementation was associated with some beneficial changes in the composition of the colonic microbiota,Salmonella sh

关键词： Ascophyllum nodosum Gastrointestinal microbiota Inflammation Pig Salmonella Seaweed extract Zinc oxide

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