检索结果-南通市图书馆

Treatment and prevention of epilepsy in onchocerciasis-endemic areas is urgently needed

Infectious Diseases of Poverty 2024年第1期13卷 85-89页

作者： Robert Colebunders Joseph Nelson Siewe Fodjo Olivia Kamoen Luis-Jorge Amaral Amber Hadermann Chiara Trevisan Mark J.Taylor Julia Gauglitz Achim Hoerauf Yasuaki Sato Katja Polman Maria-Gloria Basanez Dan Bhwana Thomson Lakwo gasim abd.elfarag Sebastien D.Pion Global Health Institute University of AntwerpAntwerpBelgium Department of Neurology Heilig Hart ZiekenhuisLierBelgium Department of Public Health Institute of Tropical MedicineAntwerpBelgium Liverpool School of Tropical Medicine LiverpoolUK Department of Computer Science University of AntwerpAntwerpBelgium Institute of Medical Microbiology Immunology and ParasitologyUniversity Hospital BonnBonnGermany German Center for Infection Research(DZIF) Partner Site Bonn-CologneBonnGermany School of Global Humanities and Social Sciences Nagasaki UniversityNagasakiJapan MRC Centre for Global Infectious Disease Analysis and London Centre for Neglected TropicalDisease Research Department of Infectious Disease EpidemiologySchool of Public HealthImperial College LondonLondonUK National Institute for Medical Research TangaTanzania Vector Control Division Ministry of HealthKampalaUganda School of Public Health University of JubaJubaSouth Sudan Access for Humanity JubaSouth Sudan French National Research Institute for Sustainable Development MontpellierFrance

Background There is increasing epidemiological evidence supporting the association between onchocerciasis and seizures, reinforcing the concept of onchocerciasis-associated epilepsy (OAE). The aim of this paper is to provide an update on the new knowledge about OAE and to propose recommendations to the World Health Organization how to address this public health *** text During the 2nd International Workshop on OAE held on 19-21 September, 2023, in Antwerp, Belgium, participants recognised OAE as a substantial yet neglected public health problem, particularly in areas of sub-Saharan Africa where onchocerciasis remains hyperendemic. Evidence from prospective population-based studies suggest that strengthening onchocerciasis elimination efforts leads to a significant reduction of OAE incidence. There is a need to validate an OAE case definition to estimate the burden of disease and identify onchocerciasis-endemic areas requiring intensification of onchocerciasis elimination programmes and integration of epilepsy care. It is expected that raising awareness about OAE will boost the population uptake of ivermectin. The implementation of a community-based epilepsy treatment programme offering free anti-seizure medications (ASMs) has shown high effectiveness in reducing the frequency of seizures and improving the overall quality of life of people with *** To reduce OAE burden, enhanced collaboration between onchocerciasis and mental health programmes at community, national, and international levels is required. Urgent efforts are needed to ensure the uninterrupted provision of free ASMs in onchocerciasis-endemic areas. Furthermore, OAE should be included in the quantification of the onchocerciasis disease burden.

关键词： Onchocerciasis Morbidity Burden of disease Prevention Ivermectin Epilepsy Nodding syndrome Treatment Children Policy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Exploration of Green Alternatives to 6PPD (P-Phenylenediamine) Used as Antiozonant and Antioxidant in the Rubber Industry

引用

Materials Sciences and Applications 2024年第4期15卷 87-100页

作者： Emine Demir Husnu Gerengi Kerem Savcı gasim Altundal Canan Yüksel Doğaç Çağıl Anlas Tyre Company R&D Center D&#252zce T&#252rkiye Department of Mechanical Engineering Faculty of Engineering D&#252zce University D&#252zce T&#252rkiye The Koc High School &#304stanbul T&#252rkiye

Antiozonants and antioxidants are additives commonly used in the rubber industry to enhance the durability and performance of rubber products. Ozone, present in the atmosphere, can cause rubber to degrade over time through a process known as ozone cracking. These rubber additives are added to rubber compounds to protect against this degradation. They work by reacting with ozone, preventing it from attacking and breaking the molecular chains in the rubber, helping to maintain the structural integrity of the rubber product. It is now well known that 6PPD contributes to the extension of the service life of rubber products. However, recent studies have shown that 6PPD can be harmful to the environment, especially when end-of-life tyres (ELTs) are contaminated with the water. With the effect of ozone, 6PPD is converted to 6PPD quinone, which is toxic enough to kill some sensitive fish species such as Coho Salmon (Oncorhynchus kisutch). This study drew attention to new chemical compounds and natural products that can be used as antiozonants and antioxidants in the rubber industry instead of 6PPD. Although the scientific studies are promising, the fact that 6PPD is still used in production shows that more scientific studies and social awareness need to be developed in this area.

关键词： 6PPD Coho Salmon Antiozonant Antioxidant

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hematological picture of pediatric Sudanese patients with visceral leishmaniasis and prediction of leishmania donovani parasite load

引用

World Journal of Clinical Cases 2024年第30期12卷 6374-6382页

作者： Zeinab Ibrahim Ahmed Elnoor Omaima abdelmajeed Alamin Mustafa Thuraya gasim Shima Algam Mohamed Musa abdelrahman Hamza abdelmoneim Islamia Ibrahim Ahmed Omer Hiba Awadelkareem Osman Fadl Department of Pathology Faculty of MedicineOmdurman Ahilia UniversityOmdurmanKhartoumSudan Mohammed Alamin Hamid Pediatric Hospital Omdurman KhartoumSudan Department of Hematology and Blood Transfusion Medicine Federal Ministry of HealthKhartoumSudan Department of Pediatrics Faculty of MedicineOmdurman Islamic UniversityOmdurmanKhartoumSudan Tropical Diseases Teaching Hospital OmdurmanKhartoumSudan Faculty of Medicine Al-Neelain UniversityKhartoumSudan Faculty of Medicine Omdurman Islamic UniversityOmdurmanKhartoumSudan Department of Pediatrics Faculty of MedicineUniversity of Science and TechnologyKhartoumSudan Department of Hematology Faculty of Medical Laboratory SciencesAl-Neelain UniversityKhartoumSudan

BACKGROUND Visceral leishmaniasis(VL)is a systemic protozoan infection caused by Leishmania donovani(***)and transmitted by sand flies,causing macrophage invasion in the liver,spleen,and bone *** of VL is currently based on clinical signs,symptoms,and specific in-vitro markers and bone marrow ***,VL's specific hematological and bone marrow manifestation in Sudanese pediatric patients is not well *** To examine the blood and bone marrow characteristics in pediatric patients from Sudan who have *** This is a retrospective hospital-based study with a sample of 107 consecutive Sudanese pediatric *** data focused on hematological and bone marrow *** included only the completed records of the pediatric patients with VL in the Tropical Disease Teaching Hospital in Khartoum,Sudan from the period of 2016 to *** The majority of pediatric patients included in this study are below 5-years-old(n=59,55.2%).Moreover,anemia,thrombocytopenia,and leukopenia were among the prevalent characteristics in the population under *** further analyze the data,we developed a machine learning model using boosted forest algorithms to predict *** parasites load,with a mean accuracy of 0.88 for the training dataset and an accuracy of 0.46,0.50,and 0.74 for mild,moderate,and severe *** parasite load in the validation *** This study shows that the most common bone marrow change among Sudanese VL children was increased chronic inflammatory cells(n=88,82.2%)with present macrophage hemophagocytes(n=103,96.3%).While anemia and thrombocytopenia were the most common hematological *** results will hopefully lead to an early diagnosis and hence better management for Sudanese pediatric patients with suspected VL.

关键词： Machine learning Bone marrow Hematological changes Tropical diseases Leishmania donovani Visceral leishmaniasis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Adaptation of Massive Open Online Courses by Chang'an University

The Adaptation of Massive Open Online Courses by Chang'an Un...

引用

作者：杰森（gasim Mohamed）长安大学

学位级别：硕士

本研究希望帮助读者一窥大规模开放在线课程技术,通过对长安大学各个学院(如经济与管理学院(SEM),土木工程学院(SCE)以及其他学院)具体院情的分析,表明了长安大学大学使用大规模开放在线课程(MOOCs)的迫切性和适用性。本研究的主要数据... 详细信息

本研究希望帮助读者一窥大规模开放在线课程技术,通过对长安大学各个学院(如经济与管理学院(SEM),土木工程学院(SCE)以及其他学院)具体院情的分析,表明了长安大学大学使用大规模开放在线课程(MOOCs)的迫切性和适用性。本研究的主要数据来源于互联网中MOOCs的相关资料。该研究试图实现以下目标:A.确认MOOCs满足对于提高国际学生入学率的需求;B.评估国际学生关于使用MOOCs作为其完成课程及日常工作的互联网工具的适应程度;C.研究互联网的某些方面,例如“如何做”你自己的视频,对互联网的搜索调查等国际学生作业时使用的研究网站。同时其中设计了一个简单的研究模型来论证预测未来人口增长率的公式,以及应用线性回归分析和皮尔森相关系数来确定该模式在现实中对长安大学的MOOCs有着显著的影响。本研究主要对240名学生进行问卷调查,共有215名实际受试者。通过封闭式问题,以及统计工具,如行业数据统计软件(SPSS V.20)和Microsoft Excel分析工具,显示变量之间的相互关系,从而确定了长安大学61%的国际学生很熟悉在线教育。这意味着学生很容易适应并使用MOOCs,同时教师对该系统同样能充分适应。研究人员认为,如果根据所取得的成果将其实际应用,通过向区域及国际推广高质量的学习和教学设施,提高学校知名度,从而提高大学的排名同时带来更多的交流机会。此外研究人员希望其能够帮助改变未来其他学者对MOOCs的看法,并为其它学习机构发展MOOCs确定一个合适的战略模式。

关键词：大规模开放在线课程统计学学生注册网络学习

来源：

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

Heterotic Effect, Combining Ability and Significance of Synthetics over Line Cultivars in Faba Bean (Vicia fabaL.) Grown under Semi-Arid Zones

引用

American Journal of Plant Sciences 2018年第13期9卷 2684-2695页

作者： Seif M. gasim Alam E. Mohamed Department of Agronomy Faculty of Agriculture University of Khartoum Shambat Sudan Department of Agronomy Faculty of Agriculture University of Zalingei Zalingei Sudan

The aim of this study was to investigate the amount of heterosis and performance of faba bean synthetic cultivars compared to line cultivars under semi-arid conditions. Five inbred lines in at least S6 generation were developed and used to develop F1s hybrid (in all possible combination excluding reciprocal), lines mixtures (Syn-0) and synthetic generations of Syn-1. Evaluation of the entries showed the lines to have high general and specific combining ability, high yield and high average degree of cross-fertilization (0.36);hetrosis relative to mid-parent for yield was 67%. Lines mixture from four inbred lines (Hudeiba/93, Bassabier, Ed-Damar and Shabah) gave the highest yield of 3.40 t/ha for Syn-0 and 3.96 t/ha for Syn-1. Compared to the average yield t/ha of the pure stand of the four lines (3.11 t/ha), the increase in yield of was 9% in sy-0 and 27% in Syn-1. Compared to the individual yield t/ha of the pure stand of the lines, the performance of Syn-0 surpassed that of the individual pure stands of the linesby 14% for Hudiaba/93 and Bassabier and 4% for Ed-Damar and 7% for Shabah, whereas the increase in performance of Syn-1 compared to pure stand of the lines was 32%, 25% and 21%, respectively. The results confirm the previous knowledge on yield increase with successive syn-generations in faba bean due to the effects of heterogeneity and heterozygosity. Such results could be used as a base for an effective breeding program for improvement of yield of faba bean grown under the semi-arid zones.

关键词： Hetrosis Synthetics Faba Bean Yield Arid-Zone

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Variation in Thermal time model Parameters Between Two Contrasting Chickpea (Cicer arietinum) cultivars

引用

Agricultural Sciences 2015年第12期6卷 1421-1427页

作者： Atif Hassan Naim Faisal El gasim Ahmed Faculty of Agricultural and Environmental Sciences University of Gadarif Gadarif Sudan Faculty of Agriculture University of Khartoum Shambat Sudan

A laboratory experiment was carried out to determine the effect of different constant temperatures on germination and early seedling establishment and to study the variation among parameters of thermal time model parameters for two contrasting chickpea cultivars . Seeds were subjected to six constant temperatures from 10 o C to 35 o C . A complete randomized design was used with four replication. Analysis of variance showed significant differences among treatments for all characters studied. The final germination percentage significantly increased with increasing temperature up to 25 ° C, and thereafter there was a sharp decrease in final germination at 30 ° and 35 ° C. Desi type cultivar (small seeded) “Jabel Marra” significantly exhibited higher final germination percentage and lower germination rate compared with the kabui type cultivar “Shendi” at all temperatures. The median (θ T(50) ) of the thermal time was significantly differ between the two chickpea cultivars. The large seeded cultivars (shendi) recorded significantly higher median thermal time than the small seeded cultivars (Jabel Marra). The results also revealed a significant differences between the two cultivars in all thermal time model parameters. The small seeded cultivar (Jabel Marra) scored lower total dry matter and temperature tolerance index (TTI) compared to the large seeded cultivar (Shendi) at all temperatures studied.

关键词： Cicer arietinum Chickpea Base temperture Germination Thermal time model

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genetic Diversity in the Semi-Arid Grown Cowpea(Vigna unguiculataL. Walp)Accessions Using Morphological and Molecular Characterization

引用

Agricultural Sciences 2020年第8期11卷 692-706页

作者： Ahmed A. Elteib Seif M. gasim Department of Agronomy Faculty of Agriculture University of Khartoum Shambat Sudan

Assessment of genetic diversity of the indigenous crop accessions is extremely important for breeders to identify potential parents in cross-breeding programs. Fourteen cowpea accessions collected from different parts of Sudan were used for characterization at morphological and molecular levels. The seeds of the accessions were sown in the field using a randomized complete block design with three replicates. Sixteen morphological descriptors (9 qualitative and 7 quantitative) and 20 Random Amplified Polymorphic DNA (RAPD) markers were used for characterization of the accessions. The results of morphological data revealed considerable variability within and between state’s accessions. Some morphological traits revealed similarity between accessions from different states. Among the 20 RAPD markers used, 18 were polymorphic. A total of 379 polymorphic patterns were generated;polymorphic information content (PIC) ranged from 0.63 to 0.98 with an average of 0.9. The number of fragment detected ranged from 2 for OPL-11 to 51 for OPY-2 with an average of 26.06/primer and 27.07/genotype. One to five (1 - 5) unique fragments of different sizes were detected for particular accessions, which may provide a valuable resource for breeding superior cowpea cultivars in Sudan and other semi-arid zones. Genetic similarity was ranged from 0.02 to 0.47 with an average of 0.25. Highe

关键词： Cowpea Accessions Genetic Diversity Characterization Morphological Markers RADP Markers Polymorphism

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Impact of Bee Pollination on Yield of Faba Bean (Vicia fabaL.) Grown under Semi-Arid Conditions

引用

Agricultural Sciences 2018年第6期9卷 729-740页

作者： Seif M. gasim Awadalla A. abdelmula Department of Agronomy Faculty of Agriculture University of Khartoum Shambat Sudan

The effect of honeybee (Apis mellifera carnica) on yield was investigated in open-pollinated faba bean cultivars and three inbred generations produced from them (once-selfed, twice-selfed, and thrice-selfed). All entries were grown in cages under two pollination conditions: presence of bees (cross-pollination) or absence of bees (self-pollination). The open-pollinated generations gave the highest performance in the presence and absence of bees. In the presence of bees, the open-pollinated and their inbred entries gave higher performance in all of the studied traits than in the absence of bees;the average improvement in yield and its components was 22%. The highest improvement percentage in yield performance was shown by more inbred entries (thrice-selfed > once-selfed), indicating that in faba bean populations, the performance of inbred generations was chiefly associated with the tripping of flowers, which is usually governed by successfully fertilized flowers, i.e., plants result from selfing in faba bean population needs to be visited by pollinating insects (bees) to set more seeds. It concluded that honeybee has an important role in increasing faba bean yield in semi-arid conditions;hence, it is important to provide a pollinator friendly environment for their foraging places and nesting sites to secure food supply.

关键词： Faba Bean Yield Honey Bees Pollination Self-Fertilization Cross-Fertilization Inbred-Generation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The effect of bi-annual community-directed treatment with ivermectin on the incidence of epilepsy in onchocerciasis endemic villages in South Sudan:a study protocol

引用

Infectious Diseases of Poverty 2018年第1期7卷 1177-1184页

作者： gasim abd.elfarag Makoy Yibi Logora Jane YCarter Morrish Ojok Jackson Songok Sonia Menon Ferdinand Wit Richard Lako Robert Colebunders Department of Global Health Academic Medical CenterUniversity of AmsterdamAmsterdamThe Netherlands Amsterdam Institute for Global Health and Development AmsterdamThe Netherlands Neglected Tropical Diseases Unit Ministry of HealthJubaRepublic of South Sudan Amref International University NairobiKenya Amref Health Africa JubaSouth Sudan Global Health Institute University of AntwerpAntwerpBelgium Policy PlanningBudgeting and ResearchMinistry of HealthJubaRepublic of South Sudan Global Health Institute University of AntwerpKinsbergen CentrumDoornstraat 3312610 AntwerpBelgium

Background:Nodding syndrome(NS)is a devastating epileptic illness of unknown aetiology mainly affecting children 5-15 years of *** nodding distinguishes NS from other forms of *** manifestations of the illness include mental and physical growth *** children die as a result of falling in fires or ***,it was shown that NS is only one of the phenotypic presentations of onchocerciasis associated epilepsy(OAE).Despite the strong epidemiological association between epilepsy and onchocerciasis,the causal mechanism is *** implementation of bi-annual community directed treatment with ivermectin(CDTi)and larviciding of rivers in northern Uganda,new cases of NS have ceased,while new cases continue to emerge in South Sudanese onchocerciasis-endemic areas with an interrupted CDTi *** study is designed to evaluate the potential effects of bi-annual CDTi on reducing the incidence of NS/OAE in onchocerciasisendemic areas in South ***:A pre-intervention door-to-door population-based household survey will be conducted in selected onchocerciasis-endemic villages in Mundri and Maridi Counties,which have a high prevalence of *** a validated questionnaire,the entire village will be screened by community research assistants for suspected epilepsy *** cases will be interviewed and examined by a trained clinical officer or medical doctor who will confirm or reject the diagnosis of ***-annual CDTi will be implemented in the villages and a surveillance system for epilepsy set *** implementing an epilepsy onchocerciasis awareness campaign we expect to obtain>90%CDTi coverage of eligible *** door-to-door survey will be repeated two years after the baseline *** incidence of NS/OAE will be compared before and after bi-annual ***:Our study is the first population-based study to evaluate the effect of bi-annual CDTi to reduce the incidence of NS/*** the study

关键词： Onchocerciasis Epilepsy Nodding syndrome South Sudan Ivermectin Community directed treatment Mundri Maridi

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Venlafaxine Dependence： A Case Report

引用

Journal of Pharmacy and Pharmacology 2016年第8期4卷 378-380页

作者： Ugur Cikrikcili gasim gasimzada Ilhan Yargic Department of Psychiatry Istanbul Faculty of Medicine University of lstanbul lstanbul 34093 Turkey

Venlafaxine, an SNRI （serotonin-norepinephrine reuptake inhibitor） drug, is commonly used to treat depression. Although it is very rare, venlafaxine may lead to addiction or abuse in some patients. To date, there are very limited data available on venlafaxine addiction. The aim of this article is to draw an attention to dependence of venlafaxine in clinical practice. Significant point of this article is： Our patient was addicted by ＂high＂ doses of venlafaxine for getting high effects. Overdose of venlafaxine produces an amphethamine-like ＂high＂ with experiences of euphoria by its ability to increase neurotransmitter levels in addiction literature [1-3]. We present a man aged 42 years, who was referred to our clinic for detoxification from venlafaxine addiction. He had been taking venlafaxine upto 1,950-2,100 mg/day to get high for the past 10 years. Physicians must be careful when prescribing antidepressants to patients, especially those with a history of alcohol and/or drug addictions or abuse.

关键词： Addiction dependence antidepressant venlafaxine.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：