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Journal of Integrative Plant Biology 2005年第8期47卷 988-997页

作者： Jie CHeN gary e HArMAN Afio COMIS Gen-Wu CHeNG School of Agriculture and Biology Shanghai Jiaotong University Shanghai 201101 China Department of Horticultural Science Cornell University New York State Agricultural Experiment Station Geneva NY 14456 USA College of Plant Protection Shenyang Agricultural University Shenyang 110161 China

Induced resistance has been evidenced as one of mechanisms of Trichoderma to control plant diseases, however, no study showed the change of host proteomics in Trichoderma-induced resistance of maize against damping-off caused by Pythium ultimum Trow. The mechanism of Trichoderma harzianum rifai for controlling maize seedling disease caused by Pythium ultimum Trow was investigated firstly by proteome technique and the result suggested that T. harzianum strain T22 was not only able to promote seedling growth but also protein accumulation. One-dimensional electrophoresis assay showed that more bands appeared on the gel with T22 or T22 combined with P. ultimum （T22 ＋ P. ultimum） treatment than with other treatments. enzyme assay showed that two chitinases of the root sample were more activated in the treatments with T22 than in the other treatments without T22. Proteins in the seedling roots from the various treatments were separated through protein extraction and 2-D electrophoresis technique. In the seedlings produced from the T22-treated seeds, there were 104 up-regulated proteins and 164 down-regulated proteins relative to the control, and 97 and 150, respectively, aftel treatment with T22 ＋ P. ultimum; however, with P. ultimum alone the values were much lower than with the other two treatments. The correlation coefficient values were 0.72, 0.51 and 0.49 for the comparison of protein spot distribution on gel among control with T22, P. ultimum and T22 ＋ P. ultimum, respectively. So it seemed that P. ultimum infection was more effective than T22 in interfering with the host proteome profile. Furthermore, analysis with MALDITOF-MAS showed that some important proteins associated with defensive reactions were identified in T22 or T22 ＋ P. ultimum treatments, including endochitinase, pathogenesis-related protein PrMS （pathogenesis-related maize seed）, GTP-binding protein, isoflavone reductase and other proteins related to respiration. All those proteins are probably part

关键词： maize inbred proteome Pythium ultimum Trow Trichoderma harzianum

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Creating a research enterprise Framework for Transdisciplinary Networking to Address the Food-energy-Water Nexus

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engineering 2022年第4期8卷 95-100页

作者： Jie Zhuang Frank e.Löffler gary S.Sayler Department of Biosystems engineering and Soil Science The University of TennesseeKnoxvilleTN 37996USA Center for environmental Biotechnology The University of TennesseeKnoxvilleTN 37996USA Institute for a Secure and Sustainable environment The University of TennesseeKnoxvilleTN 37996USA Department of Microbiology The University of TennesseeKnoxvilleTN 37996USA Department of Civil and environmental engineering The University of TennesseeKnoxvilleTN 37996USA Biosciences Division Oak Ridge National LaboratoryOak RidgeTN 37831USA

Urbanization,population growth,and the accelerating consumption of food,energy,and water(FeW)resources bring unprecedented challenges for economic,environmental,and social(eeS)*** is imperative to understand the potential impacts of FeW systems on the realization of the United Nation’s Sustainable Development Goals(SDGs)as the world transitions from natural ecosystems to managed ecosystems at an accelerating rate.A major obstacle is the complexity and emergent behavior of FeW systems and associated networks,for which no single discipline can generate a holistic understanding or meaningful *** propose a research enterprise framework for promoting transdisciplinarity and top-down quantification of the interrelationships between FeW and eeS *** enterprise efforts would emphasize increasing FeW resource accessibility by improving coordinated interplays across sectors and scales,expanding and diversifying supply-chain networks,and innovating technologies for efficient resource *** framework can guide the development of strategic solutions for diminishing the competition among FeW-consuming sectors in a region or country,and for minimizing existing inequalities in FeW availability when a sustainable development agenda is implemented.

关键词： Food energy Water Stakeholder Policy environmental sustainability

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Building a hybrid DeVS and GrASS model using a composable cellular automaton

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International Journal of Modeling, Simulation, and Scientific Computing 2016年第1期7卷 62-92页

作者： gary r.Mayer Hessam S.Sarjoughian Department of Computer Science Southern Illinois University edwardsville 61 Circle Drive EdwardsvilleIllinois 62026USA Arizona Center for Integrative Modeling&Simulation School of Computing Informaticsand Decision Systems Engineering Arizona State University699 South Mill Avenue TempeArizona 85281USA

Modeling and simulation is pervasive throughout many different *** computing technology has provided more capability,the systems being modeled and simulated have grown larger and more *** times,these large systems are managed as interacting *** it is necessary for the simulation to allow disparate subsystems to maintain their independence,then a hybrid model of the subsystems should be ***,to ease the burden of verification and validation of simulation results,a proven system theoretical modeling specification should be ***,many communities have already adopted nonsystem theoretical software solutions and established a group of domain experts familiar with these *** paper provides two things:a formal approach to building a hybrid model,and a discussion of how to incorporate a nonsystem theoretical software implementation into a proven *** first is done through the implementation of a Knowledge Interchange Broker(KIB)as an Interaction Model(IM).The second is accomplished by exemplifying the use of the IM in an agent-environment hybrid *** the hybrid model,the agent is implemented in the Discrete-event System(DeVS)specification and the environment is implemented in the Geographical resources Analysis Support System(GrASS)using a Composable Cellular Automaton(CCA)*** concept has been successfully applied to both example models and an interdisciplinary research project where the interactions between human activities and landscape processes are studied.

关键词： Multi-formalism modeling hybrid simulation composability agent cellular automata

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不锈钢薄管折弯成型与回弹有限元模拟分析

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机械制造与自动化 2024年第3期53卷 155-157,180页

作者：褚艺光周圣何统统王丙旭 gary Barber 杭州佐帕斯工业有限公司浙江杭州310018 浙江理工大学机械与自动控制学院浙江杭州310018 奥克兰大学汽车摩擦学中心美国罗彻斯特48309

基于Simufact Forming软件建立不锈钢薄管折弯成型的有限元仿真模型,模拟薄管折弯成型过程并分析接触面摩擦因数和折弯速度对薄管折弯后回弹程度的影响。结果表明:随着薄管折弯角度的不断增大,折弯区域的等效应力逐渐增大,局部高应力区... 详细信息

基于Simufact Forming软件建立不锈钢薄管折弯成型的有限元仿真模型,模拟薄管折弯成型过程并分析接触面摩擦因数和折弯速度对薄管折弯后回弹程度的影响。结果表明:随着薄管折弯角度的不断增大,折弯区域的等效应力逐渐增大,局部高应力区域增大,外侧壁厚逐渐减小,内侧壁厚逐渐增大;薄管折弯后回弹量随摩擦因数的增大或折弯速度的减小呈现先增大后减小的趋势;当摩擦因数为0.2或折弯速度为2 s内190°时,薄管的回弹量最大。该结果能够为薄管折弯成型模拟仿真和回弹量预测提供一定的参考。

关键词：不锈钢薄管折弯成型回弹有限元模型模拟分析

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The Dallas Donation after Circulatory Death Transplantation Summit:expanding donation after circulatory death procedures through process improvement,broader utilization,and innovation

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Hepatobiliary Surgery and Nutrition 2024年第5期13卷 824-836,I0009页

作者： Michele Finotti Anji Wall Anthony D’Alessandro gary Schwartz Chris Sonnenday David Goldberg Ashish Shah Peter Friend Jeff P.Orlowski Greg McKenna Steve Newton Brad Adams William C.Chapman Amit Mathur Marwan Abouljoud Tim Pruett Amelia Hessheimer James F.Trotter Sumeet K.Asrani Giuliano testa Simmons Transplant Institute Baylor University Medical CenterDallasTXUSA Hepatobiliary and General Surgery Unit Regional Hospital TrevisoDISCOGUniversity of PaduaPaduaItaly Division of Transplantation Department of SurgeryUniversity of Wisconsin School of Medicine and Public HealthMadisonWIUSA Department of Thoracic Surgery and Lung Transplantation Baylor University Medical CenterCenter for Advanced Heart and Lung DiseaseDallasTXUSA Department of Surgery University of MichiganAnn ArborMIUSA Division of Digestive Health and Liver Diseases Department of MedicineUniversity of Miami Miller School of MedicineMiamiFLUSA Department of Cardio-Thoracic Surgery Vanderbilt University Medical CenterNashvilleTNUSA Nuffield Department of Surgical Sciences University of OxfordOxfordUK LifeShare Transplant Donor Services of Oklahoma Oklahoma CityOKUSA Administration Baylor University Medical CenterDallasTXUSA Southwest Transplant Alliance DallasTXUSA Department of Surgery/Transplantation Washington UniversitySt.LouisMOUSA Division of Transplant Surgery Department of SurgeryMayo Clinic ArizonaAlix School of MedicinePhoenixAZUSA Divisions of Transplant and Hepatobiliary Surgery Henry Ford HospitalDetroitMIUSA Department of Surgery University of MinnesotaMinneapolisMNUSA General and Digestive Surgery Hospital Universitario La PazIdiPAZMadridSpain

Despite a significant increase in utilization over the past decade,the number of donation after circulatory death(DCD)organs that are procured and transplanted in the United States(US)remains well below its *** is still room for expansion,as utilizing DCD organs to the fullest extent is currently the most viable solution to the persistent mismatch between supply and demand in *** convened a multidisciplinary transplantation summit to examine various aspects of DCD,with faculty members from around the world with clinical and academic interest in DCD donation and transplantation,including abdominal and cardiothoracic surgeons,organ procurement organization directors,hepatologists,and *** conference focused on identifying barriers to DCD organ utilization and strategies to overcome these *** divide the barriers to DCD utilization into three mains categories:(Ⅰ)policy and process variation;(II)logistical and transportation challenges;and(Ⅲ)higher risk perceptions related to DCD *** each barrier,we proposed a variety of solutions,providing an overview of the status of DCD donation in the US and suggestions on how to increase the use of *** is a specific focus on ex situ machine perfusion,normothermic regional perfusion,and other opportunities to expand DCD utilization without negatively impacting recipient outcomes.

关键词： Donation after circulatory death donation(DCD donation) marginal graft donor pool machine perfusion(MP)

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The relationship between sleep disorders and testosterone in men

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Asian Journal of Andrology 2014年第2期16卷 262-265,I0009,I0010页

作者： gary Wittert Discipline of Medicine and Freemasons Foundation Centre for Men's Health University of Adelaide Adelaide South Australia Australia.

Plasma testosterone levels display circadian variation, peaking during sleep, and reaching a nadir in the late afternoon, with a superimposed ultradian rhythm with pulses every 90 min reflecting the underlying rhythm of pulsatile luteinizing hormone （LH） secretion. The increase in testosterone is sleep, rather than circadian rhythm, dependent and requires at least 3h of sleep with a normal architecture. Various disorders of sleep including abnormalities of sleep quality, duration, circadian rhythm disruption, and sleep-disordered breathing may result in a reduction in testosterone levels. The evidence, to support a direct effect of sleep restriction or circadian rhythm disruption on testosterone independent of an effect on sex hormone binding globulin （SHBG）, or the presence of comorbid conditions, is equivocal and on balance seems tenuous. Obstructive sleep apnea （OSA） appears to have no direct effect on testosterone, after adjusting for age and obesity. However, a possible indirect causal process may exist mediated by the effect of OSA on obesity. Treatment of moderate to severe OSA with continuous positive airway pressure （CPAP） does not reliably increase testosterone levels in most studies. In contrast, a reduction in weight does so predictably and linearly in proportion to the amount of weight lost. Apart from a very transient deleterious effect, testosterone treatment does not adversely affect OSA. The data on the effect of sleep quality on testosterone may depend on whether testosterone is given as replacement, in supratherapeutic doses, or in the context abuse. experimental data suggest that testosterone may modulate individual vulnerability to subjective symptoms of sleep restriction. Low testosterone may affect overall sleep quality which is improved by replacement doses. Large doses of exogenous testosterone and anabolic/androgenic steroid abuse are associated with abnormalities of sleep duration and architecture.

关键词： obesity obstructive sleep apnea shift work sleep restriction testosterone

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264米的美国魔鬼塔为什么全球登顶者不足百人？

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环球人文地理 2024年第13期 90-97页

作者：李嘉麟 Dan gary GrP Imagery kellyvandellen Kyle samantha Jacob WOLFGANG flickr

在美国怀俄明州，有一座不足300米的“矮山”。别看它不高，论起攀登难度，就连珠峰登顶者都对它望洋兴叹。在美国怀俄明州东北部，有一座由火山岩和沉积岩构成的圆柱形岩石塔——魔鬼塔。它矗立在一望无际的草原上，显得格外突兀。谁...

在美国怀俄明州，有一座不足300米的“矮山”。别看它不高，论起攀登难度，就连珠峰登顶者都对它望洋兴叹。在美国怀俄明州东北部，有一座由火山岩和沉积岩构成的圆柱形岩石塔——魔鬼塔。它矗立在一望无际的草原上，显得格外突兀。谁能相信，近百年来，能够登上264米塔顶的登山者不足百人。那么，魔鬼塔是怎么形成的呢？这个问题，让好事者争论了一百多年。

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MAGNeTIC reSONANCe OF CHINeSe COALS

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Science China Mathematics 1988年第8期31卷 968-978页

作者：叶朝辉,rOBerT A.WIND,gary e.MACIeL Laboratory of Magnetic resonance and Atomic and Molecular Physics Wuhan Institute of Physics Academia Sinica Department of Chemistry Colorado State University USA. Department of Chemistry Colorado State University USA.

This paper studies ten Chinese coals at different ranks by means of cross polarization and magic angle spinning, combined rotation and multiple-pulse spectroscopy, and dynamic nuclear polarization. NMr is first reported. It is found that, compared with those obtained previously coat somples from other parts of the world, some Chinese coals at lower ranks display unusual characteristics, which imply peculiar chemical structures in the coals.

关键词： NMr of coals dynamic nuclear polarization high resolution NMr in solids aromaticity of coals.

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Turbulence modelling of the aerodynamic interaction ofOGV wakes and diffuser flow

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航空动力学报 2011年第10期26卷 2302-2312页

作者： Page gary McGuirk Jim Department of Aeronautical and Automotive engineering Loughborough University

Different turbulence closures were used to predict the flow interaction between the wakes created by compressor outlet guide vanes(OGVs) and a downstream annular *** statistical turbulence models were tested based on the classical reynolds-averaged Navier-Stokes(rANS) *** high-re and low-re(Launder-Sharma) versions of the k-ε model were applied to a selected test problem for OGV wake/diffuser *** test problem was specifically chosen because experimentally determined inlet conditions and both profile and performance data were available to validate predictions.A preliminary study was also reported of the more advanced large eddy simulation(LeS) *** LeS sub-grid-scale(SGS) model was the basic Smagorinsky eddy viscosity assumption,with a Van-Driest damping function for improved capture of near-wall viscous *** between the two rANS models showed little difference in terms of velocity contours at OGV trailing edge and diffuser *** terms of overall diffuser performance(static pressure recovery and total pressure loss coefficients),the high-re model was shown to agree well with experimental *** preliminary LeS study indicates the highly unsteady character of the OGV wake flow,but requires improved treatment of inlet conditions.

关键词： outlet guide vane(OGV) wakes diffuser flow interaction reynolds-averaged Navier-Stokes(rANS) modelling large eddy simulation(LeS) modelling

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rNA binding proteins in spermatogenesis： an in depth focus on the Musashi family

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Asian Journal of Andrology 2015年第4期17卷 529-536页

作者： Jessie M Sutherland Nicole A Siddall gary r Hime eileen A McLaughlin School of environmental and Life Sciences University of Newcastle Callaghan NSW 2308 Australia Anatomy and Neuroscience University of Melbourne ParkvilleVIC 3010 Australia

Controlled gene regulation during gamete development is vital for maintaining reproductive potential. During the complex process of mammalian spermatogenesis, male germ cells experience extended periods of the inactive transcription despite heavy translational requirements for continued growth and differentiation. Hence, spermatogenesis is highly reliant on mechanisms of posttranscriptional regulation of gene expression, facilitated by rNA binding proteins （rBPs）, which remain abundantly expressed throughout this process. One such group of proteins is the Musashi family, previously identified as critical regulators of testis germ cell development and meiosis in Drosophila, and also shown to be vital to sperm development and reproductive potential in the mouse. This review describes the role and function of rBPs our recent knowledge of the Musashi proteins in spermatogenesis. within the scope of male germ cell development, focusing on The functional mechanisms utilized by rBPs within the cell are outlined in depth, and the significance of sub-cellular localization and stage-specific expression in relation to the mode and impact of posttranscriptional regulation is also highlighted. We emphasize the historical role of the Musashi family of rBPs in stem cell function and cell fate determination, as originally characterized in Drosophila and Xenopus, and conclude with our current understanding of the differential roles and functions of the mammalian Musashi proteins, Musashi-1 and Musashi-2, with a primary focus on our findings in spermatogenesis. This review highlights both the essential contribution of rBPs to posttranscriptional regulation and the importance of the Musashi family as master regulators of male gamete development.

关键词： gene regulation Musashi Musashi-1 Musashi-2 posttranscriptional control rNA binding proteins spermatogenesis splicing testis translation

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