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The effect of EMG magnitude on the masseter vestibular evoked myogenic potential(mVEMp)

Journal of Otology 2022年第4期17卷 203-210页

作者： Daniel J.Romero gary p.jacobson Richard A.Roberts Department of Hearing and Speech Sciences Division of Vestibular SciencesVanderbilt University Medical Center121521st Ave.South6308 Medical Center EastNashvilleTN37232-8718USA

Introduction:The masseter vestibular evoked myogenic potential(mVEMp)is a bilaterally generated,electromyographically(EMG)-mediated response innervated by the trigeminal *** purpose of the present investigation was to 1)determine whether subjects could accurately achieve and maintain a range of EMG target levels,2)to examine the effects of varied EMG levels on the latencies and amplitudes of the mVEMp,and 3)to investigate the degree of side-to-side asymmetry and any effects of EMG ***:Subjects were nine neurologically and otologically normal young adults.A high-intensity tone burst was presented monaurally while subjects were seated upright and asked to match a range of EMG target levels by clenching their *** were made from the ipsilateral and contralateral masseter muscles referenced to the ear being monaurally ***:We found that the tonic EMG target had no effect on mVEMp ***,although mVEMp amplitudes“scaled”to the EMG target,there was a tendency for the subjects’EMG level to“undershoot”the EMG target levels greater than 50 *** some individuals did generate differences in EMG activation between sides,there were no significant differences on average EMG activation between ***,while average corrected amplitude asymmetry was similar across EMG targets,some individuals demonstrated large,corrected amplitude asymmetry ***:The results of this investigation suggest that,as with cVEMp recordings,the underlying EMG activation may vary between subjects and could impact mVEMp amplitudes,yet could be mitigated by amplitude correction *** it is important to be aware that even young normal subjects have difficulty maintaining large,tonic EMG activity during the mVEMp recording.

关键词： Vestibular evoked myogenic potentials (VEMps) Masseter VEMps Electromyography(EMG) Vestibulomasseteric reflex(VMR) EMG target Level

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A factor analytic assessment of the English translation of the neuropsychological vertigo inventory(NVI)

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Journal of Otology 2020年第2期15卷 45-49页

作者： gary p.jacobson Erin G.piker Kelsey Hatton Richard A.Roberts Vanderbilt University Medical Center NashvilleTNUSA James Madison University HarrisonburgVAUSA

purpose:Vestibular impairments have been associated with a variety of cognitive deficits,most notably deficits in visuo-spatial *** Neuropsychological Vertigo Inventory(NVI)was developed to measure self-reported cognitive deficits in patients with dizziness and/or *** original French language version of the NVI includes 28 items and 7 *** purpose of the present investigation was to determine whether the statistical assessment of an English language version supported the presence of the same cognitive constructs as the French version of the ***:The English language adaptation of the NVI(referred to here as the NVIe)was administered to an unselected sample of 280 patie nts that were being evaluated for dizziness and/or vertigo in a tertiary care dizziness *** individual item scores from the NVIe were subjected to an exploratory factor analysis(EFA).Results:The results of the data analysis supported a 22-item NVIe consisting of 4 constructs:affective state,temporal memory,spatial memory,visual spatial ***:The NVIe is a new tool for screening cognitive constructs that may be affected by vestibular *** to clinical implementation of the NVIe,additional studies of reliability and convergent validity are needed.

关键词： Cognition Vestibular Construct validity

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Age predicts the absence of caloric-induced vertigo

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Journal of Otology 2018年第1期13卷 5-9页

作者： gary p.jacobson Erin G.piker Sarah L.Grantham Lauren N.English Department of Hearing and Speech Sciences Divisions of Audiology and Vestibular Sciences Vanderbilt University Medical Center Nashville TN USA Department of Communication Sciences and Disorders James Madison University Harrisonburg VA USA

Introduction: The absence of vertigo during the caloric test, despite a robust response, has been suggested to represent a central vestibular system phenomenon. The purpose of this investigation was to determine the prevalence of absent caloric-induced vertigo perception in an unselected group of patients and to assess possible predicting ***: prospective investigation of 92 unselected patients who underwent caloric testing. Inclusion criteria were that each patient generate a maximum slow phase velocity(maxSpV) > 15 deg/sec and a caloric asymmetry of≤10%. Following the caloric, patients were asked, "Did you have any sensation of motion?"Results: Results showed 75% of patients reported motion with a mean age of 56.51 years compared to a mean age of 66.55 in the 25% of patients reporting an absence of motion. A logistic regression was performed and the overall model was statistically significant accounting for 29% of the variance in caloric perception. The significant predictor variables were patient age and maxSpV of the caloric response. The effect size for both variables was small with an odds ratio of.9 for maxSpV and 1.06 for ***: The current investigation showed that both age and maxSpV of the caloric response were significant predictors of vertigo perception during the caloric exam. However, the association between age and caloric perception is not conclusive. Although there is evidence to suggest that these findings represent age-related changes in the central processing of vestibular system stimulation, there are additional unmeasured factors that influence the perception of caloric-induced vertigo.

关键词： Vestibular Vertigo Central processing Caloric test Aging

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Recovery rates of persistent post-COVID-19 olfactory dysfunction using psychophysical assessment:A longitudinal cohort study

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第2期10卷 79-87页

作者： Jeremy p.Tervo patricia T.jacobson Brandon J.Vilarello Tiana M.Saak Francesco F.Caruana Liam W.Gallagher Joseph B.gary David A.Gudis paule V.Joseph D.p.Devanand Terry E.Goldberg Jonathan B.Overdevest Columbia University Vagelos College of physicians and Surgeons New YorkNew YorkUSA Department of Otolaryngology-Head and Neck Surgery New York-Presbyterian/Columbia University Irving Medical CenterNew YorkNew YorkUSA Department of Otolaryngology-Head and Neck Surgery University of PittsburghPittsburghPennsylvaniaUSA Department of Otolaryngology-Head and Neck Surgery University of MinnesotaMinneapolisMinnesotaUSA National Institute of Alcohol Abuse and Alcoholism Section of Sensory Science and Metabolism&National Institute of Nursing ResearchBethesdaMarylandUSA New York-presbyterian/Columbia University Irving Medical Center New YorkNew YorkUSA

Objectives:persistent olfactory dysfunction(OD)following loss of smell associated with SARS-CoV-2 infection is a major feature of long *** on the prevalence of persistent OD predominantly rely on self-reported olfactory *** studies have tracked longitudinal rates of recovery using psychophysical assessment among patients presenting for evaluation of persistent OD beyond a window of acute *** anchored in standardized testing methods are needed to counsel patients who fail to acutely regain their sense of *** study aims to quantify the degree of persistent OD in post-COVID-19 patients who experience subjective and psychophysical ***:We grouped participants presenting for OD evaluation into cohorts based on both subjective and psychophysical olfactory status at a baseline assessment and assessed their olfactory abilities with a visual analogue scale and the Sniffin'Sticks extended test at baseline and 1-year time *** had confirmed a history of COVID-19 by lab evaluation or clinical diagnosis if lab evaluation was not ***:Baseline olfactory evaluation was completed by 122 participants,53 of whom completed the 1-year follow-up *** participants presenting with perceived OD,74.5%had confirmed psychophysical OD at baseline,with 55.1%at 1-year *** had reliable trends in self-rated versus psychophysically tested olfactory function at both time *** total threshold,discrimination,and identification(TDI)score improved by+3.25 points in the cohort with psychophysical OD(p=0.0005),with this improvement largely attributable to an increase in median threshold scores(+2.75 points;p=0.0004).Conclusions:OD persists in a significant number of patients who fail to acutely recovery their sense of smell after COVID-19,with many demonstrating lingering deficits at *** in threshold,but not discrimination or identification,most significantly mediate improvement

关键词： long COVID olfaction post-COVID condition smell dysfunction

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环境友好型海洋防污剂的性能研究

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中国涂料 2012年第5期27卷 43-46页

作者： Andrew H.jacobson gary L.Willingham 贺晓蓉陶氏微生物控制技术部上海200021

综述对比了三丁基锡(TBT)与Sea-Nine 211作为海洋防污剂在防污性能以及环境影响等方面的效果。Sea-Nine可以被微生物迅速降解,其好氧及厌氧条件下的半衰期均小于1 h。Sea-Nine的降解产物为开环衍生物,其毒性已大大降低。TBT降解的产物... 详细信息

综述对比了三丁基锡(TBT)与Sea-Nine 211作为海洋防污剂在防污性能以及环境影响等方面的效果。Sea-Nine可以被微生物迅速降解,其好氧及厌氧条件下的半衰期均小于1 h。Sea-Nine的降解产物为开环衍生物,其毒性已大大降低。TBT降解的产物之一为二丁基锡衍生物,仍然具有毒性并且在环境中不易降解。

关键词：防污剂有机锡环境分布异噻唑啉酮 Sea-Nine

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