检索结果-南通市图书馆

The effect of EmG magnitude on the masseter vestibular evoked myogenic potential(mVEmP)

2004年

作者： gary R. mORRISON STEVEN m. ROSS JERROLD E. KEmP.

来源：畅想之星图书光盘版（南... 评论

在线全文

畅想之星图书光盘版（南通市图书馆镜像）

学校读者我要写书评

暂无评论

Journal of Otology 2022年第4期17卷 203-210页

作者： Daniel J.Romero gary P.Jacobson Richard A.Roberts Department of Hearing and Speech Sciences Division of Vestibular SciencesVanderbilt University Medical Center121521st Ave.South6308 Medical Center EastNashvilleTN37232-8718USA

Introduction:The masseter vestibular evoked myogenic potential(mVEmP)is a bilaterally generated,electromyographically(EmG)-mediated response innervated by the trigeminal *** purpose of the present investigation was to 1)determine whether subjects could accurately achieve and maintain a range of EmG target levels,2)to examine the effects of varied EmG levels on the latencies and amplitudes of the mVEmP,and 3)to investigate the degree of side-to-side asymmetry and any effects of EmG ***:Subjects were nine neurologically and otologically normal young adults.A high-intensity tone burst was presented monaurally while subjects were seated upright and asked to match a range of EmG target levels by clenching their *** were made from the ipsilateral and contralateral masseter muscles referenced to the ear being monaurally ***:We found that the tonic EmG target had no effect on mVEmP ***,although mVEmP amplitudes“scaled”to the EmG target,there was a tendency for the subjects’EmG level to“undershoot”the EmG target levels greater than 50 *** some individuals did generate differences in EmG activation between sides,there were no significant differences on average EmG activation between ***,while average corrected amplitude asymmetry was similar across EmG targets,some individuals demonstrated large,corrected amplitude asymmetry ***:The results of this investigation suggest that,as with cVEmP recordings,the underlying EmG activation may vary between subjects and could impact mVEmP amplitudes,yet could be mitigated by amplitude correction *** it is important to be aware that even young normal subjects have difficulty maintaining large,tonic EmG activity during the mVEmP recording.

关键词： Vestibular evoked myogenic potentials (VEmPs) masseter VEmPs Electromyography(EmG) Vestibulomasseteric reflex(VmR) EmG target Level

Tumor necrosis factor-α inhibitor therapy and fetal risk:A systematic literature review

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2013年第17期19卷 2591-2602页

作者： Renée m marchioni gary R Lichtenstein Division of Gastroenterology and Hepatology University of Connecticut Health Center Division of Gastroenterology Hospital of the University of Pennsylvania

Tumor necrosis factor-α inhibitors (anti-TNFs) are effective in the treatment of inflammatory bowel disease (IBD) recalcitrant to conventional medical therapy. As the peak incidence of IBD overlaps with the prime reproductive years, it is crucial to establish pharmacologic regimens for women of childbearing age that achieve effective disease control without posing significant fetal harm. A systematic literature review was performed to identify all human studies with birth outcomes data after maternal exposure to infliximab, adalimumab, or certolizumab pegol within 3 mo of conception or during any trimester of pregnancy. Live births, spontaneous abortions or stillbirths, preterm or premature births, low birth weight or small for gestational age infants, and congenital abnormalities were recorded. Fifty selected references identified 472 pregnancy exposures. The subsequent review includes general information regarding anti-TNF therapy in pregnancy followed by a summary of our findings. The benefits of biologic modalities in optimizing disease control during pregnancy must be weighed against the potential toxicity of drug exposure on the developing fetus. Although promising overall, there is insufficient evidence to prove absolute safety for use of anti-TNFs during pregnancy given the limitations of available data and lack of controlled trials.

关键词： Tumor necrosis factor-α inhibitors Pregnancy Congenital abnormalities Safety Infliximab Adalimumab Certolizumab

Heavy metals leaching in bottom ash and fly ash fractions from industrial-scale BFB-boiler for environmental risks assessment

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Transactions of Nonferrous metals Society of China 2016年第1期26卷 256-264页

作者： Risto POYKIO mikko mAKELA gary WATKINS Hannu NURmESNIEmI OUi DAHL Department of Environmental Protection City ofKemiValtakatu 26FI-94100 KemiFinland Division of Biomass Technology and Chemistry Department of Forest Biomaterials and TechnologySwedish University of Agricultural SciencesP.O.Box SLUSE-90183 UmehSweden Department of Environmental Science and Technology Tokyo Institute of Technology4259 Nagatsuta-choMidori-kuYokohama 226-8502Japan Department of Forest Products Technology School of Chemical TechnologyAalto UniversityP.O.Box 16400FI-00076 AaltoFinland Department of Environmental Protection Stora Enso OyjVeitsiluoto MillFI-94800 KemiFinland

The bottom ash and fly ash from the co-combustion of wood residues and peat at a bubbling fluidised bed boiler（296 mW） contained only quartz（SiO_2）, microcline（KAl Si_3O_8） and albite（NaAlSi_3O_8）. Thus, X-ray powder diffraction（XRD） was not useful for clarifying the difference in the release of associated heavy metals from ash matrices. In order to assess the release of heavy metals from ashes under changing environmental conditions, they were sequentially extracted and fractionated by the BCR-procedure into acid soluble/exchangeable（CH_3COOH）, reducible（NH_2OH-HCl） and oxidizable（H_2O_2/CH_3COONH_4） phases. The CH_3 COOH extractable fraction in conjunction with the total heavy metals concentrations were used to calculate the risk assessment code values for heavy metals leaching from the ash matrix. The leaching studies indicate that the heavy metals in the bottom ash and fly ash are bound to different fractions with different strengths. From the environmental and utilization perspectives, heavy metals in ashes posed different levels of environmental contamination risk. Only As in the bottom ash posed a very high risk. High risk metals were Cd in the bottom ash as well as As, Cd and Se in the fly ash.

关键词： bottom ash fly ash BCR extraction heavy metals risk assessment code

Vegetarian diets,circulating miRNA expression and healthspan in subjects living in the Blue Zone

在线全文

学校读者我要写书评

暂无评论

Precision Clinical medicine 2020年第4期3卷 245-259页

作者： Tiantian Liu Nicole m.Gatto Zhong Chen Hongyu Qiu Grace Lee Penelope Duerksen-Hughes gary Fraser Charles Wang Center for Genomics School of MedicineLoma Linda UniversityLoma LindaCA 92350USA School of Community and Global Health Claremont Graduate UniversityClaremontCA 91711USA Center of molecular and Translational medicine Institution of Biomedical ScienceGeorgia State UniversityAtlantaGA 30303USA Department of Psychology School of Behavioral HealthLoma Linda UniversityLoma LindaCA 92350USA Department of Basic Sciences School of MedicineLoma Linda UniversityLoma LindaCA 92350USA School of Public Health Loma Linda UniversityLoma LindaCA 92350USA

A long-term vegetarian diet plays a role in the longevity and maintenance of the healthspan,but the underlying mechanisms for these observations are largely ***,it is not known whether a longterm vegetarian dietary pattern may affect the circulating miRNA expression in such a way as to modulate the *** Adventist Health Study-2(AHS-2)cohort includes a large number of older adults who primarily follow vegetarian dietary patterns and reside in Loma Linda,California,one of five“Blue Zones”in the world in which a higher proportion of the population enjoys a longer than average *** performedmiRNA-seq in 96 subjects selected from the AHS-2 cohort with different dietary *** identified several differentially expressed miRNAs between vegetarians and non-vegetarians,which are involved in immune response and cytokine signaling,cell growth and proliferation as well as age-related diseases such as cardiovascular diseases and neurodegenerative ***,our study showed that a vegetarian diet modulates aging-associated circulating miRNAs in a sex-dependent manner of differential expression for certain miRNAs,which may be related in a beneficial manner to the *** investigation is needed to validate these miRNAs as potential biomarkers for diet-modulated longevity in humans.

关键词： circulating miRNA aging miRNA sequencing vegetarian diet Blue Zone

Golgi protein-73:A biomarker for assessing cirrhosis and prognosis of liver disease patients

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2020年第34期26卷 5130-5145页

作者： Nikolaos K Gatselis Tamás Tornai Zakera Shums Kalliopi Zachou Asterios Saitis Stella Gabeta Roger Albesa gary L Norman mária Papp George N Dalekos Department of medicine and Research Laboratory of Internal medicine National Expertise Center of Greece in Autoimmune Liver DiseasesGeneral University Hospital of LarissaLarissa 41110Greece Institute of Internal medicine and Hepatology Larissa 41447Greece Department of Internal medicine Division of GastroenterologyUniversity of DebrecenFaculty of MedicineDebrecen H-4032Hungary Department of Research and Development Inova DiagnosticsInc.San DiegoCA 92131United States

BACKGROUND Reliable biomarkers of cirrhosis,hepatocellular carcinoma(HCC),or progression of chronic liver diseases are *** this context,Golgi protein-73(GP73)also called Golgi phosphoprotein-2,was originally defined as a resident Golgi type II transmembrane protein expressed in epithelial *** a result,GP73 expression was found primarily in biliary epithelial cells,with only slight detection in ***,in patients with acute or chronic liver diseases and especially in HCC,the expression of GP73 is significantly up-regulated in *** far,few studies have assessed GP73 as a diagnostic or prognostic marker of liver fibrosis and disease *** To assess serum GP73 efficacy as a diagnostic marker of cirrhosis and/or HCC or as predictor of liver disease *** GP73 serum levels were retrospectively determined by a novel GP73 ELISA(QUANTA Lite®GP73,Inova Diagnostics,Inc.,Research Use Only)in a large cohort of 632 consecutive patients with chronic viral and non-viral liver diseases collected from two tertiary Academic centers in Larissa,Greece(n=366)and Debrecen,Hungary(n=266).Aspartate aminotransferase(AST)/Platelets(PLT)ratio index(APRI)was also calculated at the relevant time points in all *** hundred and three patients had chronic hepatitis B,183 chronic hepatitis C,198 alcoholic liver disease,28 autoimmune cholestatic liver diseases,15 autoimmune hepatitis,and 5 with other liver-related *** duration of follow-up was 50(57)mo[median(interquartile range)].The development of cirrhosis,liver decompensation and/or HCC during follow-up were assessed according to internationally accepted *** particular,the surveillance for the development of HCC was performed regularly with ultrasound imaging and alpha-fetoprotein(AFP)determination every 6 mo in cirrhotic and every 12 mo in non-cirrhotic *** Increased serum levels of GP73(>20 units)were detected at initial evaluation in 277 out of

关键词： Biomarker Golgi protein-73 Hepatic fibrosis Cirrhosis Hepatocellular carcinoma Hepatitis B Hepatitis C Aspartate aminotransferase/Platelets ratio index score

The Human Role in Constructing Settlement Patterns and Landscapes:A Caution Based on Systematic Archaeological Survey in Coastal Shandong Province,China

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

东方考古 2016年第1期 1-15页

作者： gary m.Feinman Linda m.Nicholas Fang Hui The Field museum Shandong University

Introduction The recent advances in archaeobotany that have fostered our understanding of agricultural origins and variable crop regimes across Neolithic and Bronze Age Eastern Asia represent major contributions for which we applaud our colleagues who have presented their discoveries and results at this *** findings help us see how early villagers in this part of the world constructed diverse niches that they inhabited thousands of years ago.

关键词： Constructing Settlement Patterns Landscapes Survey

Elevated mercury in Ambient Air and Soils Impacts of Historical Air Emissions (1897-1991) from a Chlor-Alkali Plant (CAP)

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Protection 2016年第3期7卷 435-452页

作者： gary Hunt TRC Environmental Corporation Lowell USA

mercury contamination was found to be widespread in soils at a property in Upstate New York. Historical site use suggested that the mercury did not result from prior industrial use of the property. Soil contamination may have resulted from atmospheric deposition of mercury released from properties in close proximity to the contaminated property. The purpose of this forensics investigation was to examine to what extent atmospheric deposition of elemental mercury may have influenced mercury levels found in surficial soils on the contaminated property and further to identify the source(s) of the mercury. Work efforts included an examination of historical records available for a chlor-alkali plant (CAP) upwind of the contaminated property to establish historical use and disposal practices for elemental mercury. mercury emissions test data from the Upstate New York chlor-alkali facility were modeled (USEPA ISC3) as a means of estimating impacts on ambient air and soils vicinal to the facility. mercury emissions from the facility were modeled as both a point source and volume source. For example, at a location 305 meters to the east and 30 meters to the north of the modeled source centerline elemental mercury concentrations in ambient air were estimated at 270 ng/m3 (average results based upon 5 years of meteorological data). This value is contrasted to a background concentration of 1.6 ng/m3 (USEPA Report to Congress 1997). As a result of the modeling data in combination with findings related to mercury use and disposal practices at the NY CAP documented from the records review, it was concluded that emissions from the CAP facility during the period of operation (1897-1991) most likely accounted for the concentrations of elemental mercury found in surficial soils at properties situated downwind of the CAP. These findings were further corroborated by information available in the open literature for CAPs world-wide.

关键词： mercury Air Emissions Chlor-Alkali (CAP) manufacturing Dispersion modeling Deposition Rates

An overview of the role of neutrophils in innate immunity,inflammation and host-biomaterial integration

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Regenerative Biomaterials 2017年第1期4卷 55-68页

作者： Gretchen S.Selders Allison E.Fetz marko Z.Radic gary L.Bowlin Department of Biomedical Engineering University of MemphisMemphisTNUSA Department of microbiology Immunology and BiochemistryUniversity of Tennessee Health Science Center(UTHSC)MemphisTN 38163USA

Despite considerable recent progress in defining neutrophil functions and behaviors in tissue repair,much remains to be determined with regards to its overall role in the tissue integration of *** article provides an overview of the neutrophil’s numerous,important roles in both inflammation and resolution,and subsequently,their role in biomaterial *** function in three primary capacities:generation of oxidative bursts,release of granules and formation of neutrophil extracellular traps(NETs);these combined functions enable neutrophil involvement in inflammation,macrophage recruitment,m2 macrophage differentiation,resolution of inflammation,angiogenesis,tumor formation and immune system *** exhibit great flexibility to adjust to the prevalent microenvironmental conditions in the tissue;thus,the biomaterial composition and fabrication will potentially influence neutrophil behavior following *** review serves to highlight the neutrophil’s plasticity,reiterating that neutrophils are not just simple suicidal killers,but the true maestros of resolution and regeneration.

关键词： neutrophil tissue engineering NETosis tissue regeneration host response inflammation

A new spallation mechanism of thermal barrier coatings on aero-engine turbine blades

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Theoretical & Applied mechanics Letters 2018年第1期8卷 7-11页

作者： Bo Yuan Christopher m.Harvey Rachel C.Thomson gary W.Critchlow Simon Wang Department of Aeronautical and Automotive Engineering Loughborough University Department of materials Engineering Loughborough University School of mechanical and Equipment Engineering Hebei University of Engineering

Laboratory experiments were conducted to study the spallation behaviour of thermal barrier coatings(TBCs) on aero-engine turbine blades manufactured by the electron-beam physical vapour deposition technique(EB-PVD). Intact blades were heated at temperature 1135℃ in a furnace for certain time and then cooled to the room temperature in the laboratory condition. It was found that no spallation occurred during cooling, but spallation happened at constant room temperature after cooling. The spallation mechanism is studied by using the mechanical model developed(Harvey 2017 and Wang 2017), which are based on the hypothesis of pockets of energy concentration(PECs). Some observations of the spallation behaviour are well predicted by the model.

关键词： Thermal barrier coating Interface fracture Spallation Pockets of energy concentration Buckling