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Learning from parental experience in a neonatal surgical unit:a qualitative service evaluation

World Journal of Pediatric Surgery 2023年第3期6卷 147-153页

作者： Anna Littlejohns Emile Crouzen Rebecca Mernenko Fiona Metcalfe Waaka Moni-Nwinia Hemma Chauhan Bethan Johnson Douglas McConachie Elizabeth Lawson Victoria Tricklebank John G McElwaine Gurdeep S Sagoo Liz McKechnie gary latchford Jonathan Sutcliffe Anaesthesia and Critical Care Leeds Teaching Hospitals NHS TrustLeedsUK Paediatric Surgery Leeds Children's HospitalLeedsUK Leeds Centre for Newborn Care Leeds Children's HospitalLeedsUK Faculty of Medicine and Health University of LeedsLeedsUK Academic Unit of Health Economics University of LeedsLeedsUK Institute of Health Sciences University of Leeds LeedsLeedsUK St James's University Hospital Department of Clinical and Health Psychology LeedsUK

Objectives Patient experience is directly related to health outcomes,and parental experience can be used as a proxy for this in neonatal *** project was designed to assess parental experience of neonatal surgical care to inform future service developments and improve the care we *** This was a qualitative study using rapid qualitative *** study was carried out in a large neonatal surgical intensive care unit in the *** of infants treated by the neonatal surgical team between March 2020 and February 2021,during the COVID-19 pandemic were *** sampling was used to ensure that a representative range of parents were interviewed.A semistructured interview was created and tested in a previous phase of *** questionnaire was used to ask parents open questions about different aspects of their infants’healthcare journey from the antenatal phase through to discharge from the neonatal unit(NUU).Results Rapid qualitative analysis was employed,and parental experiences were grouped into five main categories:before admission to the NNU,initial admission to NNU,information and support,COVID-19 and *** these five groups,we highlighted positive experiences to be fed back to the healthcare teams to reinforce good practice,areas that warranted improvement and suggestions for service *** The wealth of data generated from the interviews has been summarized and shared with healthcare teams who are putting the service improvement suggestions into *** tool is available for services that wish to measure parental experience.

关键词： qualitative service interview

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Triassic integrative stratigraphy,biotas,and paleogeographical evolution of the Qinghai-Tibetan Plateau and its surrounding areas

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Science China Earth Sciences 2024年第4期67卷 1152-1194页

作者： Guichun WU Zhansheng JI gary GLASH Qinggao ZENG Jianxin YAO Key Laboratory of Stratigraphy and Palaeontology Ministry of Natural ResourcesInstitute of GeologyChinese Academy of Geological SciencesBeijing 100037China SinoProbe Laboratory Chinese Academy of Geological SciencesBeijing 100094China Department of Geology and Environmental Sciences State University of New York-FredoniaFredoniaNY 14063USA Xizang Autonomous Region Geological and Mineral Exploration and Development Burea Lhasa 850010China

Rocks of the Qinghai-Tibetan Plateau(QTP)host abundant Triassic *** far,the well established marine fossil sequences based on ammonoids,conodonts,bivalves,brachiopods,radiolarians,and terrestrial spora-pollen sequence have become standard for biostratigraphic correlation of the *** much of Triassic time,the QTP occupied a marine setting as suggested by the dominance of marine *** main sedimentary types represented in the Triassic successions include littoral to shallow marine clastic rocks,shallow marine carbonate platform carbonates,bathyal to abyssal slope carbonates intercalated with clastic and siliceous deposits,coal-bearing clastic strata contained within paralic facies deposits,and littoral and terrestrial volcaniclastic *** deposits are organized into four stages in ascending order:(1)Early Triassic deposits that record marine transgression,including extensive shallow marine carbonate platform strata.(2)Middle Triassic Ladinian to Late Triassic Carnian deposits,including thin-bedded limestone,fine clastics,and siliceous rocks,that accumulated at greater depths than underlying Early Triassic strata and reflect the peak of the *** activity appears to have occurred in some areas during this stage.(3)Late Triassic Norian deposits that record the onset of marine regression as suggested by the widespread occurrence of platform *** is noteworthy that stage 3 deposits of the Qin-Qi-Kun area in the northernmost region of the QPT is dominated by terrestrial strata and displays evidence of local erosion.(4)Late Triassic Rhaetian littoral and shallow marine clastic and coal-bearing deposits that preserve the record of continued marine regression *** Indus-Yarlungzangbo Suture Zone(IYSZ)appears to have been the rifting axis during Triassic time as suggested by sedimentary facies trends that reflect deepening to south and ***,the Himalaya Block to the south of the IYSZ was part of the passive margin

关键词： Qinghai-Tibetan Plateau Triassic Biostratigraphy Lithostratigraphy Palaeobiogeography Sedimentary palaeogeography

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Application of a simplified ADM1 for full-scale anaerobic co-digestion of cattle slurry and grass silage:assessment of input variability

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Frontiers of Environmental Science & Engineering 2024年第4期18卷 125-139页

作者： Sofia Tisocco Sören Weinrich gary Lyons Michael Wills Xinmin Zhan Paul Crosson Civil Engineering College of Science and EngineeringUniversity of GalwayGalwayH91 TK33Ireland Teagasc Animal and Bioscience Research Department Animal and Grassland Research and Innovation CentreDunsanyC15 PW93Ireland Biochemical Conversion Department Deutsches Biomasseforschungszentrum gemeinnützige GmbHLeipzig 04347Germany Faculty of Energy·Building Services·Environmental Engineering Münster University of Applied SciencesSteinfurt 48565Germany Agri-Food and Biosciences Institute HillsboroughBT266DRUK Ryan Institute University of GalwayGalwayH91 TK33Ireland MaREI Research Centre for Energy Climate and MarineRyan InstituteUniversity of GalwayGalwayH91 TK33Ireland

Mathematical modeling of anaerobic digestion is a powerful tool to predict gas yields and optimize the *** Anaerobic Digestion Model No.1(ADM1)is a widely implemented model for this ***,modeling full-scale biogas plants is challenging due to the extensive substrate and parameter characterization *** study describes the modification of the ADM1 through a simplification of individual process phases,characteristic components and required ***,the ability of the simplified model to simulate the co-digestion of grass silage and cattle slurry was evaluated using data from a full-scale biogas *** impacts of substrate composition(crude carbohydrate,protein and lipid concentration)and variability of carbohydrate degradability on simulation results were assessed to identify the most influential *** indicated that the simplified version was able to depict biogas and biomethane production with average model efficiencies,according to the Nash-Sutcliffe efficiency(NSE)coefficient,of 0.70 and 0.67,respectively,and was comparable to the original ADM1(average model efficiencies of 0.71 and 0.63,respectively).The variability of crude carbohydrate,protein and lipid concentration did not significantly impact biogas and biomethane output for the data sets *** contrast,carbohydrate degradability seemed to explain much more of the variability in the biogas and methane ***,the application of simplified models provides a reliable basis for the process simulation and optimization of full-scale agricultural biogas plants.

关键词： ADM1 Agricultural feedstocks Biogas technology Input variability Parameter estimation

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Leflunomide: A versatile additive for defect reduction, enhanced optoelectronic properties and environmental stability of perovskite films

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Nano Research 2024年第4期17卷 2628-2637页

作者： Dingyue Sun Ming Peng Taijin Wang Longju Yi Shizuo Zhang Feng Liu gary J.Cheng The Institute of Technological Sciences Wuhan UniversityWuhan 430072China School of Power and Mechanical Engineering Wuhan UniversityWuhan 430072China School of Industrial Engineering Purdue UniversityWest LafayetteIN 47906USA

The development of perovskite photoelectric devices with excellent performance is largely dependent on the defects in the perovskite *** address this issue,a specific drug,leflunomide(LF,C_(12)H_(9)F_(3)N_(2)O_(2)),was incorporated into the perovskite to reduce defects and improve its photoelectric *** is believed that the C=O bond on LF molecule can interact with the uncoordinated Pb2+of the perovskite,thereby reducing non-radiative *** novel approach of incorporating LF into perovskite films has the potential to revolutionize the development of high-performance perovskite photoelectric *** trifluoromethyl functional(–CF_(3))group on LF can form a protective layer on the surface of the perovskite film,shielding it from water ***,LF can be utilized to alter the nucleation position of perovskite,thus minimizing the number of defects and optimizing the film ***,the LF-doped perovskite film displays low trap density and high photoelectric *** LF-doped perovskite film showed a trap density of 8.28×10^(11),which is notably lower than the 2.04×10^(12) of the perovskite film without *** responsivity and detectivity of the LF-doped perovskite photodetector were 0.771 A/W and 2.81×10^(11) Jones,respectively,which are much higher than the 0.23 A/W and 1.06×10^(10) Jones of the LF-undoped perovskite ***,the LF-doped photodetector maintained an initial photocurrent of 86%after 30 days of storage in air,indicating drastically increased environmental *** strongly suggests that LF is an effective additive for perovskites utilized in optoelectronic devices with high performance.

关键词： leflunomide additive engineering defect passivation perovskite

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Revolutionizing plasmonic platform via magnetic field-assisted confined ultrafast laser deposition of high-density,uniform,and ultrafine nanoparticle arrays

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International Journal of Extreme Manufacturing 2024年第3期6卷 428-438页

作者： Jin Xu Lingfeng Wang Peilin Yang Haoqing Jiang Huai Zheng Licong An Xingtao Liu gary J Cheng School of Industrial Engineering Purdue UniversityWest LafayetteIN 47906United States of America Institute of Technological Sciences Wuhan UniversityWuhanHubei 430072People’s Republic of China

The remarkable capabilities of 2D plasmonic surfaces in controlling optical waves havegarnered significant ***,the challenge of large-scale manufacturing of uniform,well-aligned,and tunable plasmonic surfaces has hindered their *** address this,we present a groundbreaking tunable plasmonic platform design achieved throughmagnetic field(MF)assisted ultrafast laser direct deposition in *** precise control of metal nanoparticles(NPs),with cobalt(Co)serving as the model material,employing an MF,and fine-tuning ultrafast laser parameters,we have effectively converted coarse and non-uniform NPs into densely packed,uniform,and ultrafine NPs(~3 nm).This revolutionary advancement results in the creation of customizable plasmonic‘hot spots,’which play a pivotal role insurface-enhanced Raman spectroscopy(SERS)*** profound impact of this designable plasmonic platform lies in its close association with plasmonic resonance and *** the plasmonic nanostructures resonate with incident light,they generate intense local electromagnetic fields,thus vastly increasing the Raman scattering *** enhancement leads to an outstanding 2–18 fold boost in SERS performance and unparalleled sensing sensitivity down to 10^(-10)***,the plasmonic platform also demonstratesrobustness,retaining its sensing capability even after undergoing 50 cycles of rinsing andre-loading of ***,this work adheres to green manufacturing standards,making it an efficient and environmentally friendly method for customizing plasmonic‘hot spots’inSERS *** study not only achieves the formation of high-density,uniform,and ultrafine NP arrays on a tunable plasmonic platform but also showcases the profound relation betweenplasmonic resonance and energy *** outstanding results observed in SERS sensors further emphasize the immense potential of this technology for energy-relatedapplications,including photocatalysis,ph

关键词： magnetic field manipulation laser deposition metasurface SERS

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New insights into nitric oxide biosynthesis underpin lateral root development

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Molecular Plant 2024年第5期17卷 691-693页

作者： Kapuganti Jagadis Gupta Nidhi Yadav Aprajita Kumari gary J.Loake National Institute for Plant Genome Research Aruna Asaf Ali MargNew Delhi 110070India Institute of Molecular Plant Sciences School of Biological SciencesUniversity of EdinburghEH93BF EdinburghUK Centre for Engineering Biology School of Biological SciencesUniversity of EdinburghEH93BF EdinburghUK

In recent years,nitric oxide(NO)has emerged as a key redox signaling molecule in plants functioning in the regulation of key developmental programs and the orchestration of responses to a plethora of environmental cues(Kolbert et al.,2019).The predominant route for the transfer of NO bioactivity is through S-nitrosylation,the addition of an NO moiety to a protein cysteine thiol to form an S-nitrosothiol(Yun et al.,2011).Specificity for this process is established by the structural constraints imposed by tertiary protein structure in gating access to given cysteine redox switches and associated proteins that can either facilitate the addition or removal of the NO moiety at these residues(Umbreen et al.,2018).

关键词： moiety addition redox

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Launch of the transdisciplinary health science journal hLife

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Biosafety and Health 2024年第1期6卷 1-2页

作者： Qun Yan Kieran gary Thow Editorial office of hLife Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China The University of Chinese Academy of Sciences Beijing 101408China

The launch ceremony of the health science journal hLife was held at the Institute of Microbiology,Chinese Academy of Sciences(CAS)on 15 November *** 100 guests attended the event,including the editors-in-chief of hLife and editorial board members,representatives from sister journals,regulatory agency leaders,and leaders of the Institute of Microbiology,CAs,and other related departments(Fig.1).

关键词： journal editorial sister

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Substrate topography as a powerful tool to modify glial cell biology and interactions

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Neural Regeneration Research 2025年第5期20卷 1390-1391页

作者： Pascal Achenbach Haktan Altinova gary A.Brook Institute of Neuropathology RWTH Aachen University Hospital Department of Neurosurgery RWTH Aachen University Hospital Aachen Germany Berlin State Office for Health and Social Affairs(LAGeSo) BerlinGermany

Traumatic injuries to the central nervous system(CNS) result in disruption of the intricate network of axons which connect functionally related neurons that are widely distributed throughout the brain and spinal *** normal conditions,maintenance of this complex system is structurally and functionally supported by astrocytes (ACs)and other glial cells,the processes of which form a framework surrounding neuronal cell bodies,dendrites,axons,and synapses.

关键词： injuries topography system

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What the Tea Industry Reveals About China's Next Chapter

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Beijing Review 2024年第25期67卷 24-25页

作者： gary Sigley the Faculty of Geographical Science Beijing Normal University

China's transformation from a nation that accounted for less than 3 percent of global GDP in 1980 to around 17 percent in 2023 is an unprecedented success *** that time,China passed through various stages of developme... 详细信息

关键词： passed story Tea

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Outcomes of critically ill children with pre-existing mental health conditions

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儿科学研究(英文) 2024年第2期8卷 108-116页

作者： Krawiec Conrad Cash Morgan Ceneviva gary Tian Zizhong Zhou Shouhao Thomas Neal J. Department of Pediatrics Pediatric Critical Care Medicine Penn State Hershey Children’s Hospital Pennsylvania USA Department of Public Health Sciences Division of Biostatistics and Bioinformatics Pennsylvania State University College of Medicine Pennsylvania USA Department of Public Health Sciences Pennsylvania State University College of Medicine Pennsylvania USA

Importance: Critically ill children with pre-existing mental health conditions may have an increased risk of poor health ***: We aimed to evaluate if pre-existing mental health conditions in critically ill pediatric patients would be associated with worse clinical outcomes, compared to children with no documented mental health ***: This retrospective observational cohort study utilized the TriNetX electronic health record database of critically ill subjects aged 12-18 years. Data were analyzed for demographics, pre-existing conditions, diagnostic, medication, procedural codes, and ***: From a dataset of 102 027 critically ill children, we analyzed 1999 subjects (284 [14.2%] with a pre-existing mental health condition and 1715 [85.8%] with no pre-existing mental health condition). Multivariable analysis demonstrated that death within one year was associated with the presence of pre-existing mental health conditions (odds ratio 8.97 [3.48-23.15],P < 0.001), even after controlling for the presence of a complex chronic ***: The present study demonstrates that the presence of pre-existing mental health conditions was associated with higher odds of death within 1 year after receiving critical care. However, the confidence interval was wide and hence, the findings are inconclusive. Future studies with a larger sample size may be necessary to evaluate the true long-term impact of children with pre-existing mental health conditions who require critical care services.

关键词： Critical care Psychiatry Psychology Public health

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