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Extending the interval for port-a-cath maintenance

Modern Chemotherapy 2013年第2期2卷 15-18页

作者： Eugenia Girda Rebecca Phaeton gary l. Goldberg Dennis Y. S. Kuo Department of Obstetrics & Gynecology and Women’s Health Division of Gynecologic Oncology Albert Einstein College of Medi- cine and Montefiore Medical Center New York City USA

Objective: The objective of this study is to assess the outcome of port-a-cath (PAC) maintenance every three months in patients with gynecologic malignancies with the goal of standardizing a safe and appropriate interval that would maintain patency and minimize side effects. Methods: We performed a retrospective medical record review and evaluation of all patients with a Bard? PAC who were noted to have no evidence of disease (NED) during the years 2003 to 2010. The interval between accessions and any complications related to the presence of the PAC were recorded. Relevant complications included skin infections, bacteremia, thrombosis, and occlusions. Statistical analysis was done using the Fisher’s exact test. Results: A total of 201 patients had PAC placed and 43 patients underwent PAC accessions to maintain patency. The total number of accessions was 150 with a median number per patient of 2.0 (range 1 - 10). The mean time between flushes was 112 days (SD = 57). When comparing women in maintenance who had flushes within 90 days versus those who had flushes over 90 days apart, there was no difference in infection or occlusion rates between these groups (p = 0.515). In the Conclusion: Infections and occlusions are rare in women with gynecologic malignancies undergoing maintenance of their PAC. longer intervals between PAC flushes do not appear to affect the outcome in our patients. Our ongoing data and follow-up confirm that extending the interval of PAC accession to every 3 months, rather than monthly, is safe, effective and convenient in the patient population with gynecologic malignancies.

关键词： Indwelling Port-A-Cath Flushing Complication Prevention

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北京大学学报（医学版） 2006年第1期38卷 57-61页

作者： gary lU John ZHANG Katherine PAUPER Department of Pathology and Genetics USLabs/LabCorp Irvine California 91612 USA Department of Hematology/Oncology Quest Diagnostics/Nichols Institute San Juan Capistrano CA 92692 USA

Objective: To study the frequency of interstitial 7q deletions in B-cell lymphoproliferative disorders (B-lPDs). Methods: Cases were collected from the clinical laboratory diagnosis database at USlabs/labCorp over the past two years (2002 to 2004). Cases that showed deletions in the long arm of chromosome 7 were then reviewed. Interstitial deletions in the long arm of chromosome 7 were further investigated according to the indications for clinical laboratory studies and flow cytometry findings. The final clinical diagnosis for each case was obtained from the referring physician. Results: A total of 19 483 cases were included in this series. Eighty-five cases were observed to have either terminal or interstitial deletion in the long arm of chromosome 7. Of the 85 cases, 46 had interstitial deletions accounting for 54.1% of the 7q deletions combined. B-lPDs were found in 10 of the 46 cases, accounting for 21.7%. The B-lPDs associated with 7q interstitial deletions were diverse, including B-cell chronic lymphocytic leukemia (B-Cll) in five cases. The deleted region in the long arm of chromosome 7 in the 10 cases associated with B-lPDs was solely confined to the 7q22-q32 region. Conclusion: (1) The frequency of 7q interstitial deletions associated with B-lPDs is substantially high; (2) 7q interstitial deletions are not uncommon in B-Cll.

关键词：染色体缺失染色体白血病 B细胞慢性流式细胞术 7号染色体血液肿瘤 B淋巴细胞增生障碍

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赛门铁克用变革扭转公司的消极进取型困境

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IT时代周刊 2006年第22期16卷 76-77页

作者： gary l.Neilson 博思艾伦咨询公司

消极进取型企业是较为常见的一种公司病,且非常有迷惑性：从外表看,公司上下一团和气；但其实公司内部各方面功能已经严重失调。

关键词：赛门铁克消极进取型企业资源管理

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An Exploratory Analysis of Vegetation Strategies to Reduce Shallow landslide Activity on loess Hillslopes, Northeast Qinghai-Tibet Plateau, China

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Journal of Mountain Science 2013年第4期10卷 668-686页

作者： HU Xia-song BRIERlEY gary ZHU Hai-li lI Guo-rong FU Jiang-tao MAO Xiao-qing YU Qin-qin QIAO Na Department of Geological Engineering Qinghai University Qinghai Institute of Salt lakes Chinese Academy of Sciences School of Environment University of Auckland Private Bag 92019 Auckland City 1142New Zealand

Heavy summer rainfall induces significant soil erosion and shallow landslide activity on the loess hillslopes of the Xining Basin at the northeast margin of the Qinghai-Tibet Plateau. This study examines the mechanical effects of five native shrubs that can be used to reduce shallow landslide activity. We measured single root tensile resistance and shear resistance, root anatomical structure and direct shear and triaxial shear for soil without roots and five root- soil composite systems. Results show that Atriplex canescens （Pursh） Nutt. possessed the strongest roots, followed by Caragana korshinskii Kom., Zygophyllum xanthoxylon （Bunge） Maxim., Nitraria tangutorum Bobr. and lycium chinense Mill. Single root strength and shear resistance relationships with root diameter are characterized by power or exponential relations, consistent with the Mohr- Coulomb law. Root mechanical strength reflects their anatomical structure, especially the percentage of phloem and xylem cells, and the degree and speed of periderm lignifications. The cohesion force of root- soil composite systems is notably higher than that of soil without roots, with increasing amplitudes of cohesion force for A. canescens, C. korshinskii, Z. xanthoxylon, N. tangutorurn and l. chinense of 75.9%, 75.1%, 36.2%, 24.6% and 17.0 % respectively. When subjected to shear forces, the soil without root samples show much greater lateral deformation thanthe root-soil composite systems, reflecting the restraining effects of roots. Findings from this paper indicate that efforts to reduce shallow landslides in this region by enhancing root reinforcement will be achieved most effectively using A. canescens and C. korshinskii.