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magnetic resonance imaging-guided focused ultrasound thalamotomy launch with remote telemedicine international proctorship

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Chronic Diseases and Translational medicine 2024年第1期10卷 40-50页

作者： Igor V.Buzaev Rezida m.Galimova Dinara I.Nabiullina Sergey N.Illarioshkin Naufal Sh.Zagidullin Shamil m.Safin Department of Surgery Bashkir State Medical UniversityUfaRussia Intelligent Neurosurgery Clinic Ltd.International Medical Center V.S.Buzaev memorialUfaRussia Directorate Research Center of NeurologyVolokolamskoye ShosseMoscowRussia

Background: COVID-19 limitations have hindered the implementation of new technologies by preventing proctors from coming to the *** share our first experience of magnetic resonance imaging(mRI)-guided focused ultrasound(mRgFUS)treatment with an international remote online proctorship,and develop and evaluate the methodology of remote mRgFUS ***: This single-center,nonrandomized controlled prospective study included 94 patients:27 with essential tremor(ET)and 67 with tremor-dominant Parkinson's disease(PD).The coming of proctors was impossible,so we arranged for the remote participation of proctors from the United Kingdom,Spain,and israel.A total of 38 patients(40.4%)received telemedicine-proctored treatment(proctor group)and 56 received their treatment independently(solo group).We used the Clinical Rating Scale for Tremor(CRST)for ET patients and the Unified Parkinson's Disease Rating Scale(UPDRS)Part III for PD ***: In patients with ET,success rates were 81.8%(proctor group)and 100%(solo group)(p=0.22).CRST reduction on the treated side was 71.43%[65.83%;80.56%](proctor group)versus 60.87%[53.99;79.58](solo group)(p=0.19).None of the patients showed worsening of tremors within 1 *** patients with PD,the success rates were 92.6%(proctor group)and 100%(solo group)(p=0.08).The UPDRS Part III improvement was 30.1%(proctor group)versus 39.9%(solo group)(p=0.003).The 1-year recurrence rate was 40%(proctor group)and 17.5%(solo group)(p=0.04).No complications were observed at 6 ***: We developed a feasible and safe methodology for telemedicine remote online-proctored mRgFUS *** significant difference was observed between the solo and developed remote proctor protocols in terms of complication rate,effect,and long-term results;however,UPDRS Part III improvement was better in the PD solo *** study demonstrated that the mRgFUS international proctorship can be performed successfully remotely.

关键词： essential tremor mRgFUS Parkinson's disease proctor telemedicine

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A NEW GENERATION OF INSTRUmENTATION AND CAPABILITIES FOR ATOmIC mASS SPECTROmETRY

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光谱学与光谱分析 1999年第4期 76-78页

作者： gary m.HIEFTJE Steven J.RAY John P.GUZOWSKI Andrew m.LEACH Nicolas H.BINGS José m.COSTA-FERNANDEZ Department of Chemistry Indiana UniversityBloomingtonIndiana47405USA

Ａｔｏｍｉｃｍａｓｓｓｐｅｃｔｒｏｍｅｔｒｙ，ｅｍｂｏｄｉｅｄｕｓｕａｌｙａｓｉｎｄｕｃｔｉｖｅｌｙｃｏｕｐｌｅｄｐｌａｓｍａｍａｓｓｓｐｅｃｔｒｏｍｅｔｒｙ（ＩＣＰＭＳ）ｏｒｇｌｏｗΑｄｉｓｃｈａｒｇｅｍａｓｓｓｐ...

Ａｔｏｍｉｃｍａｓｓｓｐｅｃｔｒｏｍｅｔｒｙ，ｅｍｂｏｄｉｅｄｕｓｕａｌｙａｓｉｎｄｕｃｔｉｖｅｌｙｃｏｕｐｌｅｄｐｌａｓｍａｍａｓｓｓｐｅｃｔｒｏｍｅｔｒｙ（ＩＣＰＭＳ）ｏｒｇｌｏｗΑｄｉｓｃｈａｒｇｅｍａｓｓｓｐｅｃｔｒｏｍｅｔｒｙ（ＧＤＭＳ），...

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Assessment of Environmental Health Knowledge, Attitude and Behavior among High School Students in a USA Southeast Texas School District

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Open Journal of Preventive medicine 2017年第12期7卷 247-260页

作者： israel G. msengi Raymond Doe Health and Kinesiology Department Lamar University Beaumont USA Department of Psychology Lamar University Beaumont USA

This cross-sectional descriptive study assessed general environmental health literacy among students focusing on their knowledge, skills, attitudes and behaviors regarding the environmental health, stewardship, and sustainability, using a questionnaire consisting of 35 core questions from the Centers for Diseases Control (CDCs). Students (N = 185) from three high schools in the district were asked through their class teachers to voluntarily complete the questionnaire. Results indicated that about 41% (n = 77) of the students lacked knowledge regarding potential sources of radiation exposure and 70% (n = 133) lacked knowledge regarding radon gas being the number one risk factor for lung cancer among non-smokers. Additionally, the ANOVA test indicated significant knowledge differences among school location. Students in school #1, located in the most affluent area, had significantly higher knowledge scores (m = 4.39) than school #2 located in a moderately affluent area (m = 3.50). Furthermore, we found significant differences in ethnicity on the environmental health attitude of the high school students. Black students reported lower positive environmental health attitude (m = 29.86) than White students (m = 32.63), Hispanic students (m = 32.33) and Asian students (m = 33.84). These findings demonstrated knowledge deficiency in some key areas in environmental health particularly the environmental diseases and conditions caused by manmade hazards such as pesticides, chemicals, radiation, air, water, and soil pollution. Targeted educational interventions to increase awareness and understanding of health effects, exposure to environmental hazards and carcinogens as well as risks associated to direct exposure as in this study, radon and radiation, should be provided to high school students. Practical education through tours where students can observe directly and participating in laboratory experiments could empower the students to translate this knowledge into positive env

关键词： Environmental Health High School Students Knowledge Attitude Behavior Exposure Radon Radiation Recycling

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Accuracy and safety of partial thickness femtosecond laser radial and arcuate keratotomy incisions in porcine eyes

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Eye and Vision 2021年第1期8卷 412-421页

作者： E.Valas Teuma Frank A.Bucci Jr Raman Bedi gary Gray mark Packer LENSAR Inc.OrlandoFLUSA Bucci Laser Vision Institute Wilkes-BarreWilkes‑BarrePAUSA IrisARC ChandigarhIndia Packer Research Associates Inc.1400 Bluebell Ave.BoulderCO 80302USA

Background:To evaluate the accuracy and safety of micro radial and arcuate keratotomy incisions constructed by a femtosecond laser system with a curved contact patient interface in porcine ***:Partial thickness micro radial and arcuate keratotomy incisions were constructed in porcine eyes with a femtosecond laser system and evaluated for precision of depth,quality,and *** coherence tomography was used to determine the accuracy and precision of incision *** endothelial safety was assessed by a fluorescent live/dead cell viability assay to demonstrate laser-induced endothelial cell *** was evaluated by ease of opening and examination of ***:In two micro radial incision groups,intended incision depths of 50%and 80%resulted in mean achieved depths of 50.01%and 77.69%,*** three arcuate incision groups,intended incision depths of 80%,600μm or 100μm residual uncut bed thickness resulted in mean achieved depths of 80.16%,603.03μm and residual bed of 115μm,*** loss of endothelial cell density occurred when the residual corneal bed was maintained at a minimum of 85-116μ*** incisions were easy to open,and interfaces were ***:A femtosecond laser system with curved contact interface created precise and reproducible micro radial and arcuate keratotomy *** and precision of the incision depth and preservation of endothelial cell density demonstrated the effectiveness and safety of the system.

关键词： Partial thickness micro radial and arcuate keratotomy incisions Curved contact patient interface micro radial keratotomy Arcuate keratotomy Femtosecond laser system with curved contact interface LENSAR femtosecond laser system

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腺苷酸环化酶-cAmP-蛋白激酶A途径与免疫应答的调节

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国外医学（免疫学分册） 1989年第3期12卷 142-144页

作者： gary m Kammer 张云

腺苷酸环化酶(以下简称环化酶—译者)、第二信使cAmP 和cAmP 依赖性蛋白激酶A 是决定细胞对外界刺激发生什么反应的重要物质。如本文所述,虽然这些物质对免疫系统细胞的作用研究尚少,但是看来这个途径对B 淋巴细胞、T 淋巴细胞和巨噬细... 详细信息

腺苷酸环化酶(以下简称环化酶—译者)、第二信使cAmP 和cAmP 依赖性蛋白激酶A 是决定细胞对外界刺激发生什么反应的重要物质。如本文所述,虽然这些物质对免疫系统细胞的作用研究尚少,但是看来这个途径对B 淋巴细胞、T 淋巴细胞和巨噬细胞都起着负调节的作用。环化酶-cAmP-蛋白激酶A 途径一种酶(激素、核苷酸、炎性介质)作用于和环化酶偶联的兴奋型受体(Rs)可诱导环化酶的激活、ATP

关键词：环化酶 cAmP 蛋白激酶免疫应答

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Alan moore: storyteller=艾伦·摩尔：说书人 /

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2011年

作者： millidge gary Spencer.

来源：畅想之星图书光盘版（南... 评论

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The Longibrachiatum Clade of Trichoderma:a revision with new species

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Fungal Diversity 2012年第4期55卷 77-108页

作者： gary J.Samuels Adnan Ismaiel Temesgen B.mulaw George Szakacs Irina S.Druzhinina Christian P.Kubicek Walter m.Jaklitsch United States Department of Agriculture Agricultural Research ServiceSystematic Mycology&Microbiology LaboratoryB-010a10300 Baltimore AveBeltsvilleMD 20705USA Center for Environmental Science Institute of Marine and Environmental TechnologyUniversity of MarylandBaltimoreMD 21201USA Department of Applied Biotechnology and Food Science Budapest University of Technology and Economics(BUTE)1111 BudapestGellért ter 4Hungary Vienna University of Technology Institute of Chemical EngineeringGetreidemarkt 9/1661060 WienAustria Department of Systematic and Evolutionary Botany Faculty Centre of BiodiversityUniversity of ViennaRennweg 141030 ViennaAustria

The Longibrachiatum Clade of Trichoderma is *** new species are described(***,***,***,***,***,***,***,***).The twenty-one species known to belong to the Longibrachiatum Clade are included in a synoptic *** parareesei and *** are redescribed based on new collections or additional *** teleomorphs are reported for *** and *** described species are annotated.

关键词： Hypocrea Hypocreaceae Hypocreales Endophyte medical mycology Revision Systematics Taxonomy Soil fungi Biogeography

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土生空团菌对白云母的风化作用及解钾特性

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微生物学报 2015年第3期55卷 282-291页

作者：彭云湘宋淼 israel Pedruzzi 李平于建国华东理工大学化学工程联合国家重点实验室上海200237

【目的】为了提高森林土壤含钾硅酸盐矿物利用率和改善树木钾素营养,探讨外生菌根真菌对白云母矿物的解钾及风化效应。【方法】通过5种外生菌根真菌在贫钾条件下与白云母的相互作用,考察了3种常用培养基对菌株解钾能力的影响;采用解钾... 详细信息

【目的】为了提高森林土壤含钾硅酸盐矿物利用率和改善树木钾素营养,探讨外生菌根真菌对白云母矿物的解钾及风化效应。【方法】通过5种外生菌根真菌在贫钾条件下与白云母的相互作用,考察了3种常用培养基对菌株解钾能力的影响;采用解钾效果最高的土生空团菌在modified melin-Norkrans(mmN)培养基条件下,进一步研究了21d浸出过程中主要矿质元素的释放量、生物量、剩余葡萄糖量、产生的小分子有机酸种类及含量、菌丝-矿物微环境的改变,利用扫描电子显微镜观测白云母被风化的痕迹。【结果】培养基对不同外生菌根真菌解钾能力的影响各异,其中土生空团菌在mmN培养基条件下解钾能力最强,其解钾量与生物量、剩余葡萄糖量、pH值显著相关。土生空团菌能够分泌有助于菌丝-矿物粘附的胞外多糖以形成菌丝-矿物微环境,并富集有机酸,促进微环境内钾的释放;菌丝不仅能够粘附在白云母表面产生刻蚀作用,还能破坏矿物深入其内部。【结论】外生菌根真菌具有促进白云母风化并释放钾素的能力,这种能力可能与菌丝、有机酸、多糖的协同作用有关。

关键词：外生菌根真菌含钾硅酸盐矿物白云母解钾风化土生空团菌

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DESIGNING EFFECTIVE INSTRUCTION / 4th ed.

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2004年

作者： gary R. mORRISON STEVEN m. ROSS JERROLD E. KEmP.

来源：畅想之星图书光盘版（南... 评论

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The effect of EmG magnitude on the masseter vestibular evoked myogenic potential(mVEmP)

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Journal of Otology 2022年第4期17卷 203-210页

作者： Daniel J.Romero gary P.Jacobson Richard A.Roberts Department of Hearing and Speech Sciences Division of Vestibular SciencesVanderbilt University Medical Center121521st Ave.South6308 Medical Center EastNashvilleTN37232-8718USA

Introduction:The masseter vestibular evoked myogenic potential(mVEmP)is a bilaterally generated,electromyographically(EmG)-mediated response innervated by the trigeminal *** purpose of the present investigation was to 1)determine whether subjects could accurately achieve and maintain a range of EmG target levels,2)to examine the effects of varied EmG levels on the latencies and amplitudes of the mVEmP,and 3)to investigate the degree of side-to-side asymmetry and any effects of EmG ***:Subjects were nine neurologically and otologically normal young adults.A high-intensity tone burst was presented monaurally while subjects were seated upright and asked to match a range of EmG target levels by clenching their *** were made from the ipsilateral and contralateral masseter muscles referenced to the ear being monaurally ***:We found that the tonic EmG target had no effect on mVEmP ***,although mVEmP amplitudes“scaled”to the EmG target,there was a tendency for the subjects’EmG level to“undershoot”the EmG target levels greater than 50 *** some individuals did generate differences in EmG activation between sides,there were no significant differences on average EmG activation between ***,while average corrected amplitude asymmetry was similar across EmG targets,some individuals demonstrated large,corrected amplitude asymmetry ***:The results of this investigation suggest that,as with cVEmP recordings,the underlying EmG activation may vary between subjects and could impact mVEmP amplitudes,yet could be mitigated by amplitude correction *** it is important to be aware that even young normal subjects have difficulty maintaining large,tonic EmG activity during the mVEmP recording.

关键词： Vestibular evoked myogenic potentials (VEmPs) masseter VEmPs Electromyography(EmG) Vestibulomasseteric reflex(VmR) EmG target Level

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