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Phospholemman磷酸化调节小鼠和人的血管张力、血压及高血压

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中华高血压杂志 2021年第3期29卷 232-232页

作者：刘青(译) 练桂丽(摘/审校) Boguslavskyi A Tokar S Prysyazhna O Rudyk O Sanchez-Tatay D Lemmey HA Dora KA garland cj Warren HR Doney A Palmer CNA Caulfield MJ Vlachaki Walker J Howie J Fuller W Shattock MJ 不详

平滑肌钠-钾-ATP酶(Na+-K+-ATPase, NKA)可调节血管张力和血压早已为人熟知,但其辅助蛋白phospholemman(PLM)的作用尚未明确。该研究的目的是验证如下假说:在体外,PLM磷酸化可调节血管张力;在体内和人体的实验模型中,这一机制对血管功... 详细信息

平滑肌钠-钾-ATP酶(Na+-K+-ATPase, NKA)可调节血管张力和血压早已为人熟知,但其辅助蛋白phospholemman(PLM)的作用尚未明确。该研究的目的是验证如下假说:在体外,PLM磷酸化可调节血管张力;在体内和人体的实验模型中,这一机制对血管功能和血压的调节起着重要作用。

关键词：血管张力血管功能实验模型 PLM 高血压平滑肌磷酸化调节

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美国死刑的特殊形式

犯罪研究 2024年第3期 100-112页

作者： [美]大卫·加兰德李波刘熙阳(译) 蒋济泽(校) 美国纽约大学中国海洋大学法学院同济大学法学院

在其他西方国家已经废除死刑之际,美国仍然保留着死刑。传统的思考方式倾向于在美国的“保留”和其他西方国家的“废除”之间提出一个简化的、二元论的问题,但这种方式往往会忽略诸多影响因素,从而产生一个极具误导性的答案。美国的死... 详细信息

在其他西方国家已经废除死刑之际,美国仍然保留着死刑。传统的思考方式倾向于在美国的“保留”和其他西方国家的“废除”之间提出一个简化的、二元论的问题,但这种方式往往会忽略诸多影响因素,从而产生一个极具误导性的答案。美国的死刑以及刑事政策与其他西方国家相比既有自己的独特之处,但也存在着共性。不能单纯地将两者之间的差异诉诸美国例外主义,要想更好地解释两者之间的差异,需要关注美国目前实施死刑的独特制度与文化形式。本文通过揭示美国死刑的特殊形式,并通过对私刑与当代死刑关系的探讨,解释了当代美国保留死刑的原因。

关键词：美国死刑美国例外主义特殊形式私刑

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Chronic liver disease in Aboriginal North Americans

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World Journal of Gastroenterology 2008年第29期14卷 4607-4615页

作者： John D Scott Naomi garland Department of Medicine Division of Allergy and Infectious Diseases University of WashingtonSeattle WA 98144 United States Department of Laboratory Medicine University of WashingtonSeattle WA 98144 United States

A structured literature review was performed to detail the frequency and etiology of chronic liver disease (CLD) in Aboriginal North Americans. CLD affects Aboriginal North Americans disproportionately and is now one of the most common causes of death. Alcoholic liver disease is the leading etiology of CLD, but viral hepatitis, particularly hepatitis C, is an important and growing cause of CLD. High rates of autoimmune hepatitis and primary biliary cirrhosis (PBC) are reported in regions of coastal British Columbia and southeastern Alaska. Non-alcoholic liver disease is a common, but understudied, cause of CLD. Future research should monitor the incidence and etiology of CLD and should be geographically inclusive. In addition, more research is needed on the treatment of hepatitis C virus (HCV) infection and non-alcoholic fatty liver disease (NAFLD) in this population.

关键词： Hepatitis C virus Hepatitis B virus American Indian Alaska Native Chronic liver disease

Vivid birds do not initiate flight sooner despite their potential conspicuousness

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Current Zoology 2015年第4期61卷 773-780页

作者： Nicholai M. HENSLEY Jonathan P. DRURY Theodore garland, Jr. Daniel T. BLUMSTEIN Department of Ecology Evolution and Marine Biology University of Califomia Santa Barbara CA USA Department of Ecology and Evolutionary Biology University of California Los Angeles CA 90095-1606 USA Institude de Biologie de I'ENS 46 Rue d'Ulm 75005 Paris France Department of Biology University of California Riverside CA 92521 USA

The distance from an approaching threat at which animals initiate flight - flight-initiation distance （FID） -- is a sensitive metric of variation in risk, but the effects on FID associated with the risk of possessing highly detectable external coloration are unknown. We tested whether variation in the degree of plumage vividness in birds explained variation in flight-initiation distance. After controlling for body mass, the distance at which the experimental approach began, and phylogenetic relatedness, plumage vividness was not a predictor of FID. Contrary to the expectation that vividness affects risk, and therefore risk assess- ment, these results suggest that birds do not compensate for greater visual conspicuousness by fleeing sooner from approaching threats [Current Zoology 61 （4）： 773-780, 2015].

关键词： Antipredator behavior Body size Coloration Comparative method Conspicuousness Flight Initiation Distance

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I'II Be Fine

英语学习 1996年第9期 54-60页

作者：金莹 Sylvia garland

本篇描述了一位女学生与其老师 *** 的三次倾谈。从中我们知道在她年幼时父母离异。她与母亲生活,与继父 Ra1ph 的关系一直处于紧张、僵持的状态。最后终因软弱的母亲将原本供她上大学的积蓄交给继父为他的儿子买车而导致激烈冲突并被... 详细信息

本篇描述了一位女学生与其老师 *** 的三次倾谈。从中我们知道在她年幼时父母离异。她与母亲生活,与继父 Ra1ph 的关系一直处于紧张、僵持的状态。最后终因软弱的母亲将原本供她上大学的积蓄交给继父为他的儿子买车而导致激烈冲突并被赶出家门。在极度痛苦中,女主人公再次鼓起与命运抗争的勇气。

关键词： I’II Be Fine Be II

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死刑与美国文化

中外法学 2005年第6期17卷 703-726页

作者： David garland 江溯美国纽约大学法学院北京大学法学院

一、引言这是一篇关于死刑和美国文化的论文，其出发点是近来出版的一些著作和文章，这些著述认为，美国的死刑保留乃是一种潜在的文化传统的体现，这种文化传统在美国社会与处决刑事罪犯之间创造了一种选择性亲和（elective affinity... 详细信息

一、引言这是一篇关于死刑和美国文化的论文，其出发点是近来出版的一些著作和文章，这些著述认为，美国的死刑保留乃是一种潜在的文化传统的体现，这种文化传统在美国社会与处决刑事罪犯之间创造了一种选择性亲和（elective affinity）。这些新文献所暗示的——有时是明示的——主张是，当今的死刑制度乃是“美国例外主义”（American Exceptionalism）的一个例证，是一种深层的、持久的环境的体现——从美国的形成岁月至今，这一环境一直决定着它。

关键词：美国文化死刑制度文化传统美国社会环境罪犯刑事

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Genetics-inspired data-driven approaches explain and predict crop performance fluctuations attributed to changing climatic conditions

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Molecular Plant 2022年第2期15卷 203-206页

作者： Xianran Li Tingting Guo Guihua Bai Zhiwu Zhang Deven See Juliet Marshall Kimberly A.garland-Campbell Jianming Yu USDA Agricultural Research ServiceWheat HealthGeneticsand Quality Research UnitPullmanWA 99164USA Department of Agronomy Iowa State UniversityAmesIA 50011USA USDA Agricultural Research ServiceHard Winter Wheat Genetics Research UnitManhattanKS 66506USA Department of Crop and Soil Sciences Washington State UniversityPullmanWA 99164USA Department of Plant Sciences University of Idaho Research and ExtensionIdaho FallsID 83402USA

Dear Editor,Genetics-focused approaches have been widely used to uncover major genetic variants associated with performance ***,manipulating,and editing genetic variants significantly improve crop ***,the genetic component explains a portion of performance variation,and the environ-mental component contributes to the remaining,often large,portion(Laidig et al.,2017;Bonecke et al.,2020;Li et al.,2021).To ensure superior and robust performance,elite varieties are extensively tested across multiple years and *** extensive performance records,coupled with climatic profiles,could be leveraged to understand climate's impact on agriculture through approaches parallel to quantitative genetics approaches(Figure 1A).

关键词： performance attributed Figure

An Alternative Technique for Determining Gravimetric Particle Mass Deposition on Filter Substrate: The Particle Extraction Method

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Open Journal of Air Pollution 2018年第4期7卷 309-321页

作者： Charity garland Samantha Delapena David Pennise Berkeley Air Monitoring Group Berkeley CA USA

Airborne particulate matter (PM) filter sample processing is susceptible to error and can present issues associated with organizing samples, tracking data, and maintaining weighing conditions. While filter weighing facilities should implement robust quality assurance and control checks to ensure that data collection is accurate and filter storage is secure, mistakes and accidents can still occur that compromise valuable data. This paper presents a novel approach to PM filter sample processing that allows for data validation or data recovery while ensuring data integrity. The technique approximates the original, unused pre-sampling weight of polytetrafluoroethylene (PTFE) filters after PM collection to determine PM mass-deposition (MD). The method describes the extraction of PM loaded on PTFE filters via sonication in relatively non-toxic solvents, methanol and distilled water. The extraction method is compared to the standard gravimetric PM MD determination method for a set of 265 PTFE filters with mean post-sampling filter mass of 116 ± 3.6 mg, mean estimated PM MD using the standard method of 367 ± 589 μg, and mean estimated PM MD using the extraction method of 371 ± 589 μg. A Deming regression comparison of the two methods yields a slope of 0.9983 and a Pearson’s r of 0.999. A Bland-Altman assessment of the percent and absolute differences between the two methods shows the limits of agreement between 32.5% and 25.5% and -61.9 and 50.1 μg, respectively. The 99% confidence interval of the mean difference in mass deposition between the two methods is -5.8 ± 4.5 μg. These data demonstrate that estimating pre-sampling PTFE filter mass by extracting PM from sampled filters is a viable technique for gravimetric filter analysis. This method is of use in recovering pre-sampling filter weights that have been lost, incorrectly measured, or otherwise compromised.

关键词： PTFE Filters Gravimetric Analysis Particulate Matter Particle Extraction Gravimetry

Streamline unsupervised machine learning to survey and graph indel-based haplotypes from pan-genomes

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Molecular Plant 2023年第6期16卷 975-978页

作者： Bosen Zhang Haiyan Huang Laura E.Tibbs-Cortes Adam Vanous Zhiwu Zhang Karen Sanguinet Kimberly A.garland-Campbell Jianming Yu Xianran Li Department of Crop and Soil Sciences Washington State UniversityPullmanWA99164USA USDA-ARS Wheat HealthGeneticsand Quality Research UnitPullmanWA 99164USA USDA-ARS Corn Insects and Crop Genetics Research UnitAmesIA 50011USA USDA-ARS Plant Introduction ResearchAmesIA 50011USA Department of Agronomy lowa State UniversityAmesIA 50011USA

Dear Editor,Pan-genomes with high quality de novo assemblies are shifting the paradigm of biology research in genome evolution,speciation,and function annotation(Shi et al.,2023).An all-vs.-all comparison across assemblies potentially overcomes the limitation of mapping short reads to a single assembly in cataloging polymorphisms,especially large insertions and deletions(indels)contributing to phenotypic variations through altering gene structure or expression(Chen et al.,2021).

关键词： overcome shifting insertion