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A Multivariate Analysis of Correlation between Severity and Duration of Symptoms, Patient Profile and Stage of Endometriosis

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Open Journal of Obstetrics and Gynecology 2016年第10期6卷 615-622页

作者： Ayalur Gopalakrishnan Radhika Sonia Chawla Priyadrshini Nanda garima yadav Gita Radhakrishnan Department of Obstetrics & Gynecology University College of Medical Sciences and Guru Teg Bahadur Hospital Delhi India

Background: Endometriosis is an important cause of infertility and chronic pelvic pain. Our study aims to understand the cause and effect relationship of endometriosis with these two clinical presentations. Objectives: 1) To study the correlation between stage of endometriosis with pain and infertility;2) To evaluate role of transvaginal ultrasound for diagnosis of endometriosis using laparoscopic diagnosis as gold standard. Methodology: Total of 89 women presenting with infertility and or pain and with laparoscopic findings of endometriosis were included in the study. The results were analysed by logistic regression. Results: The mean age of women was 29.67 years. Seventy three percent of patients had moderate to severe disease while 31.46% of patients with endometriosis were infertile. Symptom of pain could be categorised as dysmenorrhea (71.47%), dyspareunia (41.5%) and dyschezia (15.7%). There was no association of endometriosis stage with the pain type, duration of symptoms. Transvaginal ultrasound seems a reliable test for diagnosis of ovarian endometriosis and advanced stage disease. 87.5% of patients with ovarian endometrioma had advanced disease (higher than Stage II rAFS). Conclusion: No correlation was found between the stage of endometriosis and severity of symptoms. Presence of endometrioma on USG was associated with advanced stage of endometriosis.

关键词： Endometriosis Infertility Dysmenorrhoea Endometrioma

Antioxidant and modulatory role of Chlorophytum borivilianum against arsenic induced testicular impairment

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Journal of Environmental Sciences 2012年第12期24卷 2159-2165页

作者： garima Sharma Madhu Kumar Cell and Molecular Biology Laboratory Department of ZoologyCentre for Advanced studiesUniversity of RajasthanJaipur 302055India

Arsenic has a suppressive influence on spermatogenesis and induces impairment in male reproductive system due to oxidative stress. The present study was aimed to test the arsenic induced toxicity and protection by Chlorophytum borivilianum. The effect of sodium arsenite （4 mg/（kg body weight （bw）.day）） via double distilled water without or with C. borivilianum （800 mg/（kg ***）） was evaluated in Swiss albino mice for 30 days. The radical scavenging activity of the aqueous C. borivilianum root extract was measured using DPPH （1,1-diphenyl-2-picryl hydrayzyl） radical. Qualitative assessment of various cell types in the testis, sperm count and motility, testicular activity of lipid peroxidation （LPO）, reduced glutathione （GSH）, acid and alkaline phosphatase, cholesterol and serum testosterone were monitored. Arsenic treatment showed a significant increase in LPO, acid and alkaline phosphatase, cholesterol and decrease in sperm count, sperm motility, GSH and serum testosterone. Combined treatment showed significant decrease in LPO, acid and alkaline phosphatase, cholesterol and elevation in sperm count, sperm motility, GSH and serum testosterone. Testicular histopathology showed that C. borivilianum had reduced degeneration of germ cell in the seminiferous tubules and loss of sperms induced by arsenic intoxication. The results thus led us to conclude that administration of C. borivilianum root extract is found to be protective against arsenic induced toxicity.

关键词： DPPH radical assay Chlorophytum borivilianum reduced glutathione lipid peroxidation arsenic testosterone

Mineralogy and whole-rock geochemistry of the Oligocene Barail Group of rocks of Belt of Schuppen,Northeast India:Implications for tectono-provenance and paleo-weathering

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Acta Geochimica 2024年第5期43卷 904-932页

作者： Manash Pratim Gogoi Yunpeng Dong Pradip Borgohain Devojit Bezbaruah Arvind Pandey yadav Krishna Gogoi garima Konwar Gautam Raj Bawri Bubul Bharali Department of Petroleum Technology Dibrugarh UniversityAssam 786004India Department of Geology Northwest UniversityXi’an 710069China Department of Applied Geology Dibrugarh UniversityAssam 786004India Department of Statistics Central University of RajasthanAjmer 305817India Department of Geology Mizoram UniversityAizawlMizoram 796004India Department of Geology Pachhunga University CollegeAizawlMizoram 796001India

The petrographic and geochemical attributes of the Oligocene Barail Group of rocks are used to decipher the likely source area(s)or tectonic domains,as this sequence of rocks was deposited in a foreland basin governed by orogenic domain,namely the North-east Arunachal *** river system that gave rise to the Brahmaputra River(Yarlung-Tsangpo),which flowed through several tectonic domains of the Himalayan ranges,primarily from BomiChayu,Gangadese Granitoid,Higher Himalayan Leucogranites,and Namche Barwa into the proto Bengal Basin now a part of Assam Arakan Basin and Naga Schuppen Belt,was the main source of the sandstone formation of the Barail *** purpose of sandstone petrography,which combines modal analysis with XRF(Major Oxides)and HR-ICPMS(Trace&Rare Earth Elements)research,is to identify the type of source rock(s),their weathering pattern,and its paleo-environmental *** sandstones were formed from recycled orogen and include lithic and sublithic arenite variants with advanced texture and chemical *** sediments were felsic(Th/Co:1.38,Cr/Th:9.78,La/Lu:11.58,Th/Sc:0.99,Eu/Eu*:0.66,La/Sc:3.05,La/Co:4.18),with contributions from intermediate source rocks and low-rank metamorphics deposited in an active continental margin to a continental island arc *** conditions impacted the sediments of Barails,characterised by being warm and semi-humid to humid which resulted in moderate to a high degree of chemical weathering,as shown by weathering indices like CIA(79.14),PIA(85.47),CIW(86.9),WIP(32.50),ICV(0.71),and Th/U(6.03),which were further additionally supported by C-Value(1.01),PF(1.20),Sr/Cu(2.04),and Rb/Sr(0.97).

关键词： Belt of Schuppen Barail Group Sandstone Petrography Geochemistry Provenance Tectonic setting

A CLASS OF ENTIRE DIRICHLET SERIES AS AN FK-SPACE AND A FRECHET SPACE

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Acta Mathematica Scientia 2013年第6期33卷 1571-1578页

作者： Niraj KUMAR garima MANOCHA School of Applied Sciences Netaji Subhas Institute of TechnologySector 3 DwarkaNew Delhi-110078India

In the present paper we consider a class of entire functions represented by Dirichlet series whose coefficients belong to a commutative Banach algebra and prove it to be a complex FK-space and a Frechet space.

关键词： Dirichlet series Banach algebra FK-space Frechet space

Trichilia connaroides Wight an d Arnott:Ethnobotany,Phytochemistry and Pharmacology

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中国天然药物 2011年第4期9卷 241-248页

作者： garima Garg G.B.Pant University of Agriculture and Technology

Trichilia connaroides(Meliaceae) is an evergreen tree widely distributed in South and East *** has been traditionally used as an anti-feedant and in the treatment of cholera,arthritis,pharyngitis,tonsillitis and various other *** plant parts are rich in biologically active tetranortriterpenoids(limonoids) and possess good therapeutic *** present review illustrates the ethnobotanical uses and research advances till date on its phytochemical constituents and pharmacological activities so that its potential as a multipurpose medicinal agent is understood and appreciated.

关键词： Meliaceae Trichilia connaroides Tetranorterpenoids Limonoids

Correlation of Levels of Oncostatin M Cytokine in Crevicular Fluid and Serum in Periodontal Disease

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International Journal of Oral Science 2010年第4期2卷 198-207页

作者： ManojKumar Thorat Pradeep AR garima Garg Department of Periodontics Government Dental College and Research Institute

Aim The aim of this study was to measure the level of Oncostatin M （OSM） a gp130 cytokine in the gingival crevicular fluid （GCF） and serum of chronic periodontitis patients and to find any correlation between them before and after periodontal therapy （scaling and root planing,SRP）. Methodology 60 subjects （age 25-50 years） were enrolled into three groups （n=20 per group）,group Ⅰ （healthy）,group Ⅱ （gingivitis） and group III （chronic periodontitis）. Group Ⅲ subjects were followed for 6-8 weeks after the initial periodontal therapy （SRP） as the group Ⅳ （after periodontal therapy）. Clinical parameters were assessed as gingival index （GI）,probing depth （PD）,clinical attachment level （CAL）,and radiographic evidence of bone loss. GCF and serum levels of OSM were measured by using Enzyme Linked Immunosorbent Assay （ELISA）. Results It was found that mean OSM levels had been elevated in both the GCF and serum of chronic periodontitis subjects （726.65 ± 283.56 and 65.59 ± 12.37 pg·mL-1,res-pectively） and these levels were decreased proportionally after the periodontal therapy （95.50 ± 38.85 and 39.98 ± 16.69 pg·mL-1 respectively）. However,OSM was detected in GCF of healthy subjects （66.15 ± 28.10 pg·mL-1） and gingivitis-suffering subjects （128.33 ± 22.96 pg·mL-1） and was found as below the detectable limit （≈0.0 pg·mL-1） in the serum of same subjects. Significant correlation has been found between clinical parameters and GCF-serum levels of OSM. Conclusion Increased OSM level both in the GCF and serum,and the decreased levels after initial periodontal therapy （SRP） may suggest a use as an inflammatory bio-marker in the periodontal disease.

关键词： cytokine Oncostatin M chronic periodontitis gingivitis scaling and root planning

A review on phorate persistence, toxicity and remediation by bacterial communities

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Pedosphere 2022年第1期32卷 171-183页

作者： Mohd ADAR Zahoor ABABA garima KAUSHIK Department of Environmental Science School of Earth sciencesCentral University of RajasthanBandarSindriAjmer 305801India Biofertilizer Research Laboratory Division of Basic Science and HumanitiesWaduraSher-e-Kashmir University of Agricultural Sciences and TechnologySopore 193201India

Pesticides are an integral part in maintaining agriculture and horticultural productivity and play a vital role in meeting the increasing food, fiber, and fuel needs of the growing population. Globally, organophosphate pesticides(OPPs) are among the most common pesticides used due to their high proficiency and relatively low persistence in the environment. However, recent studies have reported problems due to pesticide use, e.g., phorate contamination of aquatic ecosystems(fresh and groundwater), sediments, fruits and vegetables, and forage crops. This review highlights many cases where phorate has been detected above its respective maximum residue limit values. Organophosphate pesticides, including phorate, have negative impacts on both the environment and human health. The ecological and public health concerns of recurrent pesticide utilization have encouraged the research related to environmental fate of *** is an effective, eco-friendly, and financially viable approach for the decontamination and degradation of toxic OPPs from the environment,compared to the costly, unecological, and time-consuming physicochemical approaches, which lead to the generation of byproducts of higher *** have recognized that a wide range of microbes, mainly bacteria, can degrade this extremely hazardous pesticide. Therefore, this review discusses the present pesticide scenarios, especially phorate contamination, its toxicity, biodegradation, and metabolic products via bacterial communities, both in India and globally. The latest and up-to-date literatures on the use, contamination, and bacterial application of phorate degradation are also summarized. This article offers national and international food safety organizations and public health authorities the ability to be involved in preventing the risks associated with the use of food and nutrition products contaminated with extremely toxic phorate pesticide. This article would also enable research

关键词： biodegradation bioremediation contamination organophosphate pesticide residue

Compression Molded Ultra High Molecular Weight Polyethylene-Hydroxyapatite-Aluminum Oxide-Carbon Nanotube Hybrid Composites for Hard Tissue Replacement

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Journal of Materials Science & Technology 2013年第6期29卷 514-522页

作者： Ankur Gupta garima Tripathi Debrupa Lahiri Kantesh Balani Department of Materials Science and Engineering Indian Institute of Technology KanpurKanpur 208016India Department of Mechanical and Materials Engineering.Florida International University MiamiFL 33174USA

Ultra high molecular weight polyethylene （UHMWPE） is widely used for articulating surfaces in total hip and knee replacements. In the present work, UHMWPE based polymer composites were synthesized by synergistic reinforcing of bioactive hydroxyapatite （HA）, bioinert aluminum oxide （Al2O3）, and carbon nanotubes （CNTs） using compression molding. Phase and microstructural analysis suggests retention of UHMWPE and reinforcing phases in the compression molded composites. Microstructural analysis elicited variation in densification due to the size effect of the reinforcing particles. The hybrid composites exhibited hardness, elastic modulus and toughness comparable to that of UHMWPE. The interfacial effect of reinforcement phases has evinced the effectiveness of Al2O3 over HA and CNT reinforcements, depicting synergistic enhancement in hardness and elastic modulus. Weak interfacial bonding of polymer matrix with HA and CNT requires utilization of coupling agents to achieve enhanced mechanical properties without deteriorating cytocompatible properties.

关键词： Compression molding Ultra high molecular weight polyethylene (UHMWPE) Hydroxyapatite Aluminum oxide (AI2O3) Carbon nanotubes (CNTs) Nanoindcntation

Observation of~100%valley-coherent excitons in monolayer MoS_(2) through giant enhancement of valley coherence time

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Light(Science & Applications) 2023年第8期12卷 1644-1650页

作者： garima Gupta Kenji Watanabe Takashi Taniguchi Kausik Majumdar Department of Electrical Communication Engineering Indian Institute of ScienceBangaloreIndia Research Center for Functional Materials National Institute for Materials ScienceTsukubaJapan international Center for Materials Nanoarchitectonics National Institute for Materials ScienceTsukubaJapan

In monolayer transition metal dichalcogenide semiconductors,valley coherence degrades rapidly due to a combination of fast scattering and inter-valley exchange *** leads to a sub-picosecond valley coherence time,making coherent manipulation of exciton a highly challenging task Using monolayer MoS_(2) sandwiched between top and bottom graphene,here we demonstrate fully valley-coherent excitons by observing~100%degree of linear polarization in steady state *** is achieved in this unique design through a combined effect of(a)suppression in exchange interaction due to enhanced dielectric screening,(b)reduction in exciton lifetime due to a fast inter-layer transfer to graphene,and(c)operating in the motional narrowing *** disentangle the role of the key parameters affecting valley coherence by using a combination of calculation(solutions of Bethe-Salpeter and Maiallle-Silva-Sham equations)and a careful choice of design of experiments using four different stacks with systematic variation of screening and exciton *** the best of our knowledge,this is the first report in which the excitons are found to be valley coherent in the entire lifetime in monolayer semiconductors,allowing optical readout of valley coherence possible.

关键词： coherent monolayer lifetime