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Decarbonising energy: The developing international activity in hydrogen technologies and fuel cells

Journal of Energy Chemistry 2020年第12期29卷 405-415页

作者： John Meurig Thomas peter p.Edwards peter J.Dobson gari p.o.end Department of Materials Science&Metallurgy University of CambridgeCambridge CB30FSUK King Abdulaziz City for Science and Technology(KACST)-oxford Centre of Excellence in petrochemicals and Inorganic Chemistry Laboratory University of OxfordOxford OX13QRUK The Queen’s College University of OxfordOxford OX14AWUK Annwvyn Solutions(Independent Consultant) BromleyKent BR13DWUK

Hydrogen technologies and fuel cells offer an alternative and improved solution for a decarbonised energy *** cells are electrochemical converters;transforming hydrogen (or energy sources containing hydrogen) and oxygen directly into *** hydrogen fuel cell,invented in 1839,permits the generation of electrical energy with high efficiency through a non-combustion,electrochemical process and,importantly,without the emission ofits point of ***,despite numerous efforts to exploit the obvious attractions of hydrogen technologies and hydrogen fuel cells,various challenges have been encountered,some of which are reviewed ***,however,given the exigent need to urgently seek low-carbon paths for humankind’s energy future,numerous countries are advancing the deployment of hydrogen technologies and hydrogen fuel cells not only for transport,but also as a means of the storage of excess renewable energy from,for example,wind and solar ***,hydrogen is also being blended into the natural gas supplies used in domestic heating and targeted in the decarbonisation of critical,large-scale industrial processes such as steel *** briefly review specific examples in countries such as Japan,South Korea and the people’s Republic of China,as well as selected examples from Europe and North America in the utilization of hydrogen technologies and hydrogen fuel cells.

关键词： Decarbonisation Hydrogen Energy Hydrogen Economy Fuel cells Environment Sustainability

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procedural simulation:medical student preference and value of three task trainers for ultrasound guided regional anesthesia

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World Journal of Emergency Medicine 2017年第4期8卷 287-291页

作者： Shadi Lahham Taylaur Smith Jessa Baker Amanda purdy Erica Frumin Bret Winners Sean p.Wilson Abdulatif gari John C.Fox Department of Emergency Medicine University of CaliforniaIrvineOrangeCalifornia 92868USA UC Irvine School of Medicine IrvineCaliforniaUSA

BACKGRoUND: Ultrasound guided regional anesthesia is widely taught using task trainer models. Commercially available models are often used; however, they can be cost prohibitive. Therefore, alternative "homemade" models with similar fidelity are often used. We hypothesize that professional task trainers will be preferred over homemade models. The purpose of this study is to determine realism, durability and cleanliness of three different task trainers for ultrasound guided nerve ***: This was a prospective observational study using a convenience sample of medical student participants in an ultrasound guided nerve block training session on January 24 th, 2015. participants were asked to perform simulated nerve blocks on three different task trainers including, 1 commercial and 2 homemade. A questionnaire was then given to all participants to rate their experiences both with and without the knowledge on the cost of the simulator ***: Data was collected from 25 participants. The Blue phantom model was found to have the highest fidelity. Initially, 10(40%) of the participants preferred the Blue phantom model, while 10(40%) preferred the homemade gelatin model and 5(20%) preferred the homemade tofu model. After cost awareness, the majority, 18(72%) preferred the gelatin ***: The Blue phantom model was thought to have the highest fidelity, but after cost consideration the homemade gelatin model was preferred.

关键词： Ultrasound guided nerve block Task trainer Regional anesthesia

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Sunitinib Reduces Acute Myeloid Leukemia Clonogenic Cells in Vitro and Has potent Inhibitory Effect on Sorted AML ALDH+ Cells

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open Journal of Blood Diseases 2016年第1期6卷 9-16页

作者： Asad M. Ilyas Youssri Ahmed Mamdooh gari Mohammed H. Alqahtani Taha A. Kumosani Abdulrahman L. Al-Malki Khalid o. Abualnaja Saad H. S. Albohairi Adeel G. A. Chaudhary Farid Ahmed Centre of Excellence in Genomic Medicine Research King Abdulaziz University Jeddah Saudi Arabia Department of Biochemistry Faculty of Science King Abdulaziz University Jeddah Saudi Arabia production of Bioproducts for Industrial Applications Research Group Experimental Biochemistry Unit King Fahd Medical Research Center King Abdulaziz University Jeddah Saudi Arabia Microbial Biotechnology Department National Research Center Cairo Egypt Bioactive Natural products Research Group Experimental Biochemistry Unit King Fahd Medical Research Center King Abdulaziz University Jeddah Saudi Arabia King Abdulaziz University Hospital Jeddah Saudi Arabia

Sunitinib is an orally administered, multi-target tyrosine kinase inhibitor that has been approved by the FDA for the treatment of renal cell carcinoma and imatinib resistant gastro-intestinal tumors. Anti-leukemic activity of sunitinib has been examined in early clinical trials with limited success. However, recent trials on acute myeloid leukemia (AML) patients carrying FLT3 mutations have shown promising results. Effects of sunitinib on leukemic clonogenic cells and potential leukemic stem cells have not been examined so far. We analyzed the anti-proliferative and apoptotic properties of sunitinib on AML-derived cell lines. We also tested the effect of sunitinib on AML patient derived clonogenic cells (AML-CFC), as well as flow-sorted potential leukemic progenitors. peripheral blood or bone marrow samples were obtained from newly diagnosed AML patients and flow sorted for CD34+ CD133+ or ALDH+ cells. Umbilical cord blood derived CD34+ cells were used as normal controls. Sunitinib induced growth arrest and apoptosis in AML derived cell lines. In addition, 7 μM sunitinib induced 75% reduction of AML-CFC as compared to DMSo treated control (±6.79%;n = 4). In contrast, 7 μM sunitinib treatment of umbilical cord blood derived normal CD34+ cells showed 29% reduction in AML-CFC (±6.77%;n = 5). Treatment of ALDH+ cells sorted from 2 AML cases and CD34+ CD133+ cells from one patient showed reduction of AML-CFC on treatment with sunitinib. our study highlighted a potent anti-proliferative and proapoptotic effect of sunitinib on AML cell lines, AML patient derived clonogenic cells and potential leukemic stem cells.

关键词： Acute Myeloid Leukemia Sunitinib Tyrosine Kinase Inhibitor AML-CFC Leukemic Stem Cells

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obstetric outcomes in Advanced Maternal Age among Women at King Abdulaziz University Hospital

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open Journal of obstetrics and Gynecology 2023年第1期13卷 108-120页

作者： Rawan A. gari Ghaday M. Alrefaei Shatha A. Alsuwaida Zahra M. Alalwan Zahraa H. Aljeshi Amenah H. Al Jumah Department of obstetrics and Gynecology King Abdulaziz University Hospital Jeddah Saudi Arabia Faculty of medicine King Abdulaziz University Jeddah Saudi Arabia

Background: Advanced maternal age, over 35 years, is a well-known risk factor for poor pregnancy outcomes. It is commonly associated with various pregnancy complications, such as spontaneous miscarriage, preeclampsia/ toxemia, gestational diabetes mellitus, preterm labor, stillbirth, chromosomal abnormalities, and cesarean delivery. objectives: This study assessed obstetric and neonatal complications associated with advanced maternal age. Methods: We reviewed the medical records of 199 pregnant women over 35 years old at King Abdulaziz University Hospital in Jeddah, Saudi Arabia, from January to June 2022. We gathered data on age, nationality, number of antenatal visits, results of ultrasound scans for dating and viability, nuchal translucency and anatomy surveys, medications and multivitamins taken during pregnancy, smoking status, pregnancy, and fetal complications, and mode of delivery. Results: The prevalence of obstetric complications was 71.4% (preeclampsia/toxemia, 4.5%;antepartum hemorrhage, 4%;postpartum hemorrhage, 1%;and gestational diabetes, 23.1%). The most frequent complication was preterm labor between 34 and 36 weeks (48%), and only 12.6% of all deliveries were associated with fetal and neonatal complications such as congenital anomalies and neonatal jaundice. The prevalence of anemia during pregnancy was 10.1%, 21.1%, and 28.6% in the first, second, and third trimesters, respectively, and pregnancies complicated with antepartum or postpartum hemorrhage were associated with higher rates of anemia in the second trimester. A significant relationship was found between mean maternal age (38.84 ± 2.75 years) and the development of maternal complications (p orns with neonatal complications were much more likely to be born to mothers with a history of antepartum hemorrhage and anemia in the second trimester. Conclusion: our findings confirm that pregnancy at an advanced maternal age is associated with increased overall maternal complications. T

关键词： Advanced Maternal Age preeclampsia/Toxemia pregnancy outcomes Com-plications KAUH Jeddah

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基于机载LiDAR数据估测林分平均高

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林业科学研究 2020年第4期33卷 59-66页

作者：赵勋岳彩荣李春干张丽梅谷雷西南林业大学林学院云南昆明650224 广西大学林学院广西南宁530004 西南林业大学园林园艺学院云南昆明650224

[目的]以2016年9月广西壮族自治区高峰林场实验区获取的机载LiDAR点云数据为基础,通过提取30 m×30 m空间林分尺度下的LiDAR点云特征变量实现对林分平均高的估测。[方法]首先将105块实测林分平均高度的样地数据按照3:1的比例随机划分为... 详细信息

[目的]以2016年9月广西壮族自治区高峰林场实验区获取的机载LiDAR点云数据为基础,通过提取30 m×30 m空间林分尺度下的LiDAR点云特征变量实现对林分平均高的估测。[方法]首先将105块实测林分平均高度的样地数据按照3:1的比例随机划分为训练样本(79)和检验样本(26),采用随机森林回归(RFR)和支持向量回归(SVR)两种机器学习算法对79个训练样本与对应的林分LiDAR点云特征变量回归建模。建模方案包括随机森林模型、支持向量机模型及随机森林+支持向量机组合模型。其次利用26个检验样本数据评价模型预测精度。最后统计3个模型中训练样本和检验样本对应的精度评价指标,以一个预测精度高、泛化能力强的模型作为最终模型进行林分平均高制图。[结果]表明:随机森林模型的训练样本和检验样本的决定系数(R2)分别为0.8861和0.8375,均方根误差(RMSE)分别为1.22和1.56;支持向量机模型的训练样本和检验样本的决定系数(R2)分别为0.8864和0.8409,均方根误差(RMSE)分别为1.21和1.54;组合模型的训练样本和检验样本的决定系数(R2)分别为0.8598和0.8532,均方根误差(RMSE)分别为1.35和1.48;[结论]组合模型的泛化能力及预测精度最好,支持向量机次之,最后为随机森林。利用组合模型可有效完成研究区林分平均高制图。

关键词：机载LiDAR点云数据随机森林回归支持向量回归林分平均高高峰林场

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Bioavailability of Beta Carotene in Traditional Fermented, Roasted Granules,<i>gari</i>from Bio-Fortified Cassava Roots

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Food and Nutrition Sciences 2013年第12期4卷 1247-1254页

作者： olapeju o. phorbee Ibiyemi o. olayiwola Silifat A. Sanni Department of Nutrition and Dietetics Federal University of Agriculture Abeokuta Nigeria.

Vitamin A Deficiency (VAD) is a major public health issue and of global concern, as it affects millions of preschool children and pregnant women worldwide. Bio-fortification has emerged as a technology with potential to sustainably alleviate VAD especially in the sub-Saharan Africa, using staples like cassava. This work studied bioavailability of beta carotene (BC) in two processed gari samples from bio-fortified cassava varieties: 01/1412 and 01/1371, using 40 weanling albino rats, grouped into four, acclimatized for 1 week and fed experimentally for 4 weeks. plasma beta carotene (pBC) was determined with HpLC while bioavailable BC calculated using conventional linear dose response plot. The mean rat weight gain was 5.3 g with significant difference (pong them while mean pBC was 60.5 and 61.2 μg/dL for 01/1412 and 01/1371 respectively. From this study, a large variation of pBC among animals was found with a weak linear relationship between feed and pBC, showing that BC bioavailability is not limited to intake. The BC bioavailability of the samples was between 11% and 18% with sample from variety 01/1371 recording higher percentage (18%). gari from bio-fortified cassava roots processed traditionally, had appreciable bioavailable BC, which can contribute to the fight against VAD and improve nutritional status in developing countries although the magnitude of the problem requires a combination of strategies, of which bio-fortification is just one. However, further work is necessary on public awareness and adoption of the product.

关键词： Bioavailability Bio-Fortification Beta-Carotene Cassava gari

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时间管理结合节点控制护理管理在高海拔医疗中心住院患者中的应用

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中国当代医药 2022年第21期29卷 130-133页

作者：赵艳红桑嘎日大连医科大学附属第一医院腹部急症一科辽宁大连116000 西藏自治区那曲市人民医院西藏那曲852000

目的探析在高海拔医疗中心应用时间管理结合节点控制护理管理的临床效果。方法选取2019年4月至2020年4月那曲市人民医院收治的160例住院患者作为研究对象,采用随机数字表法将其分为观察组与对照组,每组各80例。选取同期提供服务且两组... 详细信息

目的探析在高海拔医疗中心应用时间管理结合节点控制护理管理的临床效果。方法选取2019年4月至2020年4月那曲市人民医院收治的160例住院患者作为研究对象,采用随机数字表法将其分为观察组与对照组,每组各80例。选取同期提供服务且两组互不交叉的护理人员分为观察组与对照组,每组各37名。观察组实施时间管理结合节点控制护理管理,对照组实施常规护理。比较两组患者的护理不良事件发生率、满意率及两组护理人员的时间管理倾向量表评分、Maslach职业倦怠量表(服务行业版本)(MBI-HSS)评分。结果观察组患者的护理不良事件总发生率为(1.25%),低于对照组的(11.25%),患者满意率为(95.00%),高于对照组的(71.25%),差异有统计学意义(ppp<0.05)。结论时间管理结合节点控制护理管理应用于高海拔医疗中心的临床效果显著,可有效改善护理人员时间管理倾向及职业倦怠,提高患者满意度,减少护理不良事件,值得临床推广。

关键词：时间管理节点控制医疗中心住院患者

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