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Hepatic grooves:An observational study at laparoscopic surgery

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World Journal of Experimental Medicine 2024年第2期14卷 97-102页

作者： Shamir O Cawich Dexter A Thomas Fawwaz Mohammed Michael T gardner Marlene Craigie Shaneeta Johnson Ramnanand S k.dambady Department of Surgery University of the West IndiesSt Augustine 000000Trinidad and Tobago Department of Surgery Port of Spain General HospitalPort of Spain 000000Trinidad and Tobago Section of Anatomy Basic Medical SciencesUniversity of the West IndiesKingston 000000Jamaica Department of Radiology University of the West IndiesKingston 000000Jamaica Department of Surgery Morehouse School of MedicineAtlantaGA 30310United States Section of Anatomy Department of Basic Medical SciencesUniversity of the West IndiesKingston KIN7Jamaica

BACk.ROUND In traditional descriptions,the upper surface of the liver is smooth and convex,but deep depressions are variants that are present in 5%-40%of *** sought to determine the relationship between surface depressions and the *** To use exploratory laparoscopy to determine the relationship between surface depressions and the *** An observational study was performed in all patients undergoing laparoscopic upper gastro-intestinal operations between January 1,2023 and January 20,2024.A thirty-degree laparoscope was used to inspect the liver and *** surface depressions were present,we recorded patient demographics,presence of diaphragmatic bands,rib protrusions and/or any other source of compression during *** Of 394 patients,343 had normal surface anatomy,and 51(12.9%)had prominent surface depressions on the *** was no significant relationship between the presence of surface depressions and gender nor the presence of rib ***,there was significant association between the presence of surface depressions and diaphragmatic muscular bands(P<0.001).CONCLUSION With these data,the diaphragmatic-band theory has gained increased importance over other theories for surface *** studies are warranted using cross sectional imaging to confirm relationships with intersectional planes as well as beta-catenin assays in the affected liver parenchyma.

关键词： Liver Variant Vein Hepatic Surgery

Psychiatric comorbidities in epilepsy:population co-occurrence,genetic correlations and causal effects

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General Psychiatry 2024年第1期37卷 103-111页

作者： Vik.or H Ahlqvist Christina Dardani Paul Madley-Dowd Harriet Forbes Jessica Rast Caichen Zhong Renee M gardner Christina Dalman k.isten Lyal cRAIG Newschaffer Torbjorn Tomson Michael Lundberg Daniel Berglind Neil M Davies Brian k.Lee Cecilia Magnusson Dheeraj Rai Department of Global Public Health Karolinska InstitutetStockholmSweden Medical Research Council Integrative Epidemiology Unit Bristol Medical SchoolUniversity of BristolBristolUK Centre for Academic Mental Health Population Health SciencesBristol Medical SchoolUniversity of BristolBristolUK Faculty of Epidemiology and Population Health London School of Hygiene and Tropical MedicineLondonUK A.J.Drexel Autism Institute Drexel UniversityPhiladelphiaPAUSA Department of Epidemiology and Biostatistics School of Public HealthDrexel UniversityPhiladelphiaPAUSA College of Health and Human Development Pennsylvania State UniversityState CollegePAUSA Department of Clinical Neuroscience Karolinska InstitutetStockholmSweden Centre for Epidemiology and Community Medicine Region StockholmStockholmSweden k.G Jebsen Center for Genetic Epidemiology Department of Public Health and NursingNorwegian University of Science and TechnologyTrondheimNorway Division of Psychiatry University Collge LondonLondonUK Department of Statistical Sciences University Cllge LondonLondonK NIHR Biomedical Research Centre University of BristoBristolUK Avon and Wiltshire Partnership NHS Mental Health TrustBristolUK

Back.round Psychiatric comorbidities are common in patients with *** for the co-occurrence of psychiatric conditions and epilepsy remain poorly *** We aimed to triangulate the relationship between epilepsy and psychiatric conditions to determine the extent and possible origins of these *** Using nationwide Swedish health registries,we quantified the lifetime prevalence of psychiatric disorders in patients with *** then used summarydata from genome-wide association studies to investigate whether the identified observational associations could be attributed to a shared underlying genetic aetiology using cross-trait link.ge disequilibrium score ***,we assessed the potential bidirectional relationships using two-sample Mendelian *** In a cohort of 7628495 individuals,we found that almost half of the 94435 individuals diagnosed with epilepsy were also diagnosed with a psychiatric condition in their lifetime(adjusted lifetime prevalence,44.09%;95%confidence interval(Cl)43.78%to 44.39%).We found evidence for a genetic correlation between epilepsy and some neurodevelopmental and psychiatric *** example,we observed a genetic correlation between epilepsy and attention-deficit/hyperactivity disorder(r,=0.18,95%Cl 0.09 to 0.27,p<0.001)—a correlation that was more pronounced in focal epilepsy(r=0.23,95%CI 0.09 to 0.36,p<0.001).Findings from Mendelian randomisation using common genetic variants did not support bidirectional effects between epilepsy and neurodevelopmental or psychiatric *** Psychiatric comorbidities are common in patients with *** correlations may partially explain some comorbidities;however,there is little evidence of a bidirectional relationship between the genetic liability of epilepsy and psychiatric *** findings highlight the need to understand the role of environmental factors or rare genetic variations in the origins of psy

关键词： epilepsy Psychiat lifetime

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美国敦煌基金会的历史

敦煌研究 2024年第4期 30-32页

作者：克里斯蒂安·胡达克倪密·盖茨王平先敦煌基金会敦煌研究院编辑部

21世纪初，在游客数量快速增长、气候变化、城市发展造成污染加剧的情况下，莫高窟保护面临着巨大的挑战。敦煌基金会就是在这种情况下出现的。2010年，在樊院长的要求下，倪密·盖茨和李培德一起在美国特拉华州正式成立非营利组织敦煌... 详细信息

21世纪初，在游客数量快速增长、气候变化、城市发展造成污染加剧的情况下，莫高窟保护面临着巨大的挑战。敦煌基金会就是在这种情况下出现的。2010年，在樊院长的要求下，倪密·盖茨和李培德一起在美国特拉华州正式成立非营利组织敦煌基金会。自成立以来，敦煌基金会就与敦煌研究院不断发展的需求密切相关，以支持敦煌研究院建立游客中心、举办针对中国保护学者的培训项目、举办相关展览等多种方式助力敦煌文化艺术的研究与弘扬。

关键词：敦煌基金会敦煌研究院莫高窟游客中心

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哈里斯经济议程已现雏形

商业周刊（中文版） 2024年第13期 4-5页

作者： Steve Dennis Ak.yla gardner Jennifer Dlouhy Bill Allison 易语(译) 不详

哈里斯势在进行品牌重塑,重新聚焦关键成就,对现行计划作出一些调整而非推倒重来.空军二号在佐治亚州落地,美国卡玛拉·哈里斯(k.mala Harris)时代由此揭开惟幕。这位美国副总统此番吸引的民众比总统乔·拜登(Joe Biden)一年下来吸引的... 详细信息

哈里斯势在进行品牌重塑,重新聚焦关键成就,对现行计划作出一些调整而非推倒重来.空军二号在佐治亚州落地,美国卡玛拉·哈里斯(k.mala Harris)时代由此揭开惟幕。这位美国副总统此番吸引的民众比总统乔·拜登(Joe Biden)一年下来吸引的民众总数都多——这是哈里斯在南方,在一个她已重新唤起活力的南方州的实力展示。这是她的高光时刻。

关键词：美国副总统品牌重塑佐治亚州哈里斯推倒重来

Investigation of incipient faults in 66 k. oil-filled cable sealing ends

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High Voltage 2022年第4期7卷 666-675页

作者： Vidyadhar Peesapati Christos Zachariades George Callender Siyu Gao Oliver Cwik.wsk. Richard gardner Department of Electrical and Electronics Engineering The University of ManchesterManchesterUK Department of Electrical Engineering and Electronics University of LiverpoolLiverpoolUK Tony Davies High Voltage Laboratory University of SouthamptonSouthamptonUK National Grid plc WarwickUK

This paper reports on the investigation of incipient fault mechanisms of a widely used family of Cable Sealing Ends(CSEs)which use an earthed metallic clip on top of the stress cone to fasten the cable termination stress *** element simulations indicate that the clip is causing localised electric field enhancement which could also cause impurities in the oil to move towards the clip under the influence of the dielectrophoretic *** ageing tests of stress cones in the laboratory have corroborated the simulation results,with the high electric field causing degradation of the semi-conducting tape underneath the clip as well as initiation of track.ng on the surface of the stress cone originating from the edges of the *** discharge(PD)testing using a bespok. test rig in the high voltage laboratory has shown that incipient faults originating from the ageing of the solid CSE materials can only be detected after surface track.ng has pro-gressed *** then,the intermittent nature of PD activity can pose a risk.to the accurate condition assessment of CSEs if continuous monitoring is not employed and if the ultra-high frequency method is used on its own.

关键词： incipient sealing filled

The Effects of 5 Week. of Leg-Drive Training on Bench Press Performance in Recreationally-Trained,College-Age Men

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Journal of Science in Sport and Exercise 2022年第3期4卷 231-236页

作者： Jacob k.gardner Justin T.Chia Brent M.Peterson k.lsey L.Miller Department of k.nesiology and Health Science Biola University13800 Biola AveLa MiradaCA 90639USA Department of Health and Human Development Western Washington University516 High StreetBellinghamWA 98225USA

Introduction The bench press is commonly used to measure upper-body *** much emphasis has been placed on the upper-body,little is k.own about how the lower-body can play a role in bench press ***-drive is a technique that includes flexing the k.ee so the feet line up posterior to the k.ee joint,while simultaneously contracting the k.ee extensors isometrically during the *** purpose of this study was to compare strength characteristics of lifters in a standard bench press versus a leg-drive bench press over the course of 5-week. of *** Twenty-three recreationally active males(age:22.4±2.1 years,height:175.0±5.9 cm,mass:78.4±9.5 k.)were randomized into a standard bench or leg-drive bench press *** performed four sets to failure,two times per week.for five *** of interests were training volume and 1-repetition maximum(1RM)*** training volume,a 2×5(group×week.repeated measures analysis of variance(RMANOVA)was *** the 1RM’s,a 2×2×2(group×press type×time)RMANOVA was used.A priori alpha levels were set to *** Over time,both groups showed an approximate 6%increase in 1RM *** volume for week.4 was 5.6%less than week.5,but was not different from week. 1 through *** between-group differences were observed for 1RM strength or training *** This results of this work.indicates that 5 week. of leg-drive training is effective in increasing 1RM strength,but was not more effective than standard bench press ***,lifters should choose either lifting style based on personal preference.

关键词： Chest press Lower-body Weight lifting Isometric contraction

Eye contact and sociability data suggests that Australian dingoes were never domesticated

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Current Zoology 2022年第4期68卷 423-431页

作者： J William O Ballard Chloe gardner Lucille Ellem Sonu Yadav Richard I k.mp Department of Ecology Environmentand EvolutionLatrobe UniversityMelbourneVIC 3086Australia Department of BioSciences The University of MelbourneMelbourneVIC 3010Australia School of Life and Environmental Sciences University of SydneyCamperdownNSW 2006Australia Bargo Dingo Sanctuary BargoNSW 2574Australia School of Biotechnology and Biomolecular Sciences UNSW SydneySydneyNSW 2052Australia School of Psychology UNSW SydneySydneyNSW 2052Australia

Dogs were the first animal to become domesticated by humans,and they represent a classic model system for unraveling the processes of *** compare Australian dingo eye contact and socialization with Basenji and German Shepherd dog(GSD)*** dingoes arrived in Australia 5,000–8,000 BP,and there is debate whether they were domesticated before their *** Basenji represents a primitive breed that diverged from the remaining breeds early in the domestication process,while GSDs are a breed dog selected from existing domestic dogs in the late *** conducted a 4-phase study with unfamiliar and familiar investigators either sitting passively or actively calling each *** found 75%of dingoes made eye contact in each *** contrast,86%of Basenjis and 96%of GSDs made eye *** also exhibited shorter eye-gaze duration than breed dogs and did not respond to their name being called ***,quantified as a canid coming within 1m of the experimenter,was lowest for dingoes and highest for *** sociability duration,dingoes spent less time within 1m of the experimenter than either breed *** compared with previous studies,these data show that the dingo is behaviorally intermediate between wild wolves and Basenji dogs and suggest that it was not domesticated before it arrived in ***,it remains possible that the accumulation of mutations since colonization has obscured historical behaviors,and dingoes now exist in a feralized retamed *** morphological and genetic data are required to resolve this conundrum.

关键词： Basenji dingo domestication German Shepherd dog eye gaze sociability

Evaluation of combination gene therapy with PTEN and antisense hTERT for malignant glioma in vitro and xenografts

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南京医科大学学报（自然科学版） 2007年第5期27卷 440-440页

作者： You, Y. P. Geng, X. Z. Zhao, P. FU, Z. Wang, C. Z. Chao, S. W. Liu, N. Lu, A. L. gardner, k. Pu, P. Y. k.ng, C. S. Ge, Y. Judge, S. I. V. Li, Q. D. Q Nanjing Med Univ Affiliated Hosp 1 Dept Neurosurg Nanjing 210029 Peoples R China NCI Ctr Canc Res Lab Receptor Biol ＆ Gene Express N1H Bethesda MD 20892 USA. Tianjin Med Univ Gen Hasp Dept Neurosurg Tianjin 300052 Peoples R China Univ Maryland Sch Med VA Maryland Hlth Care Syst MS Ctr Excellence East Baltimore MD 21201 USA Univ Maryland Sch Med Dept Neurol Baltimore MD 21201 USA

Telomerase activation is a critical event in cell immortalization, and an increase in human telomerase revers e transcriptase(hTERT) expression is the k.y step in activating telomerase。The phosphatase and tensin homolog(PTEN) gene encodesa double-specific phosphatase that induces cell cycle arrest, inhibits cell growth, and causes apoptotic cell death。Here we evaluated a combined PTEN and antisense hTERT gene therapy for experimental glioma in vitro and in vivo。

关键词：神经胶质瘤异体移植联合治疗 hTERT 基因治疗疗效 PTEN

Pregnancy in Patients with Shone Complex: A Single-Center Case Series

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Congenital Heart Disease 2022年第2期17卷 147-160页

作者： Rachel gardner Emily Durbak.Rachael Baird k.therine Singh Jeff Chapa David Majdalany Department of Cardiology Cleveland ClinicCleveland44195USA Department of Obstetrics Cleveland ClinicCleveland44195USA Department of Cardiology Mayo ClinicPhoenix85054USA

Back.round:There is limited literature written on the course and outcomes for pregnant mothers with Shone ***:We describe a case series of five pregnancies in four women with Shone complex within a multidisciplinary cardio-obstetrics clinic from 2016–***:Maternal age ranged from 21–39 *** patients had preserved left ventricular function while one had moderately decreased *** age at presentation ranged from 6–15 *** were three successful pregnancies(mean gestational age=37 week.,range 35–39 week.)with one patient accounting for two unsuccessful *** infants were delivered via Cesarean *** infant required a NICU stay,but all other infants delivered were ***:Patients with Shone complex can have successful pregnancies although complications can occur for both the mother and the *** prenatal care,coordinated and consistent management during pregnancy,and tertiary care support can promote positive maternal and fetal outcomes.

关键词： Shone complex pregnancy cardiac disease in pregnancy women’s cardiovascular health