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An Approximation Algorithm for the Parallel-Machine Customer Order Scheduling with Delivery Time and Submodular Rejection Penalties

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Journal of the Operations Research Society of China 2024年第2期12卷 495-504页

作者： Hong-Ye Zheng Suo-Gang gao Wen Liu Bo hou School of Mathematical Sciences Hebei Normal UniversityShijiazhuang 050024HebeiChina

In this paper,we consider the parallel-machine customer order scheduling with delivery time and submodular rejection *** this problem,we are given m dedicated machines in parallel and n customer *** order has a delivery time and consists of m product types and each product type should be manufactured on a dedicated *** order is either rejected,in which case a rejection penalty has to be paid,or accepted and manufactured on the m dedicated *** objective is to find a solution to minimize the sum of the maximum delivery completion time of the accepted orders and the penalty of the rejected orders which is determined by a submodular *** design an LP rounding algorithm with approximation ratio of n+1 for this problem.

关键词： Order scheduling Delivery time Submodular rejection penalty Approximation algorithm

Hydrated Sodium Chloride Clusters: Implications for NaCl Solvation in Water

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Hydrated Sodium Chloride Clusters: Implications for NaCl Sol...

Förster resonance energy transfer reveals phillygenin and swertiamarin concurrently target AKT on different binding domains to increase the anti-inflammatory effect

第十三届全国化学动力学会议

作者： gao-lei hou Hong Jiang Yi Qin gao Wei-Jun Zheng Beijing National Laboratory for Molecular Sciences State Key Laboratory of Molecular Reaction Dynamics Institute of Chemistry Chinese Academy of Sciences College of Chemistry and Molecular Engineering Beijing National Laboratory for Molecular Sciences Peking University

＜正＞Solvation of NaCl in water is a fundamental process and is of great importance ranging from our daily life to chemistry and biology. However, its solvation mechanism at molecular level is still unclear. In this ... 详细信息

关键词： Hydrated NaCl clusters photoelectron spectroscopy quantum chemical calculations contact ion pair solvent-separated ion pair

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Chinese Chemical Letters 2024年第5期35卷 207-212页

作者： Xiaoyao Ma Jinling Zhang Ge Fang He gao Jie gao Li Fu Yuanyuan hou Gang Bai State Key Laboratory of Medicinal Chemical Biology College of Pharmacy and Tianjin Key Laboratory of Molecular Drug ResearchNankai UniversityTianjin 300000China College of Life Health Dalian UniversityDalian 116622China Dalian Fusheng Pharmaceutical Co. Ltd.Dalian 116000China

The clinical benefit of combination therapy is significant,but it is not easy to define the mechanism of complexity and *** studies illustrate that phillygenin(Phi)binds in the allosteric inhibit pocket of protein kinase B(AKT),and swertiamarin(Swe)acts on the pleckstrin homology(PH)domain of ***,the combined synergistic effect of relieving the inflammatory response has yet to be *** on high sensitivity,specificity and fast-responsibility fluorescent sensors,the Förster resonance energy transfer(FRET)technique offers a route to provide clear insights into physiological and pathological *** the study,molecular docking,the fluorescent probes of Phi and Swe for FRET were designed and *** analysis shown that Swe and Phi concurrently acted on the PH domain and allosterically inhibited pocket of AKT,*** combination of Swe and Phi significantly increased the heat stability of AKT and decreased protease-induced *** lipopolysaccharides(LPS)-induced mice and cells,the combination arrested AKT activation,nuclear factor kappa-B(NF-κB)phosphorylation,and the expression of tumor necrosis factor-α(TNF-α),interleukin(IL)-6 and *** conclusion,FRET revealed Phi and Swe concurrently targeted AKT on different domains and the combination of Phi and Swe enhanced the anti-inflammatory effect.

关键词： FRET Swertiamarin Phillygenin AKT Anti-inflammation Combinatorial drug

Multicomponent Seismic Data Reconstruction via Anti-Aliasing Vector POCS Method

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Journal of Earth Science 2024年第4期35卷 1385-1392页

作者： Fan Li Jianjun gao Yun Wang Chunming Wang Sian hou School of Geophysics and Information Technology China University of GeosciencesBeijing 100083China Research Institute of Petroleum Exploration and Development Petro ChinaBeijing 100083China

0 INTRODUCTION Due to the ability to comprehensively utilize P and S wave information,multi-component seismic exploration has already played an important role in fracture detection,lithology prediction,fluid identification,etc.,and it has also become an important technology for complex reservoir exploration(Yuan et al.,2021;Stewart et al.,2003).

关键词： reservoir Seismic prediction

Effectively improving the extreme-pressure capacity of a class of intercalated zirconium phosphate materials

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Science China(Technological Sciences) 2024年第3期67卷 753-764页

作者： NIU WenXing ZHAO XinRui YUAN Min hou ZhiGuo LIU lei XU Hong DONG JinXiang Shanxi Key Laboratory of Chemical Product Engineering Cllege of Chemical Engineering and TechnologyTaiyuan University of TechnologyTaiyuan 030024China School of Chemical and Environmental Engineering Pingdingshan UniversityPingdingshan 467000China

We studied different long-chain ammonium ions intercalated zirconium phosphate α-ZrP, methylamine intercalated ZrP(MAZrP), tetramethylammonium hydroxide intercalated ZrP(TMAH-ZrP), dodecyltrimethylammonium bromide intercalated ZrP(DTAB-ZrP), and stearyl trimethyl ammonium bromide intercalated ZrP(STAB-ZrP) as grease co-additives in combination with isobutylene sulfide(SIB). The grease with co-additives displayed excellent extreme-pressure and anti-wear ***, the combination of the longest chain ammonium ion intercalated zirconium phosphate, STAB-ZrP/SIB, had the best tribological properties. In comparison to α-ZrP, the advantage of STAB-ZrP was that it did not form a large area of the dense physical film like α-ZrP on the worn surface, but rather gave the SIB a chance to contact with the fresh metal surface to generate a chemical film. Therefore, the sub-micron physical film and nanoscale chemical film always exist side by side on the contact surface during the friction process. This intercalated α-ZrP/SIB additive has great potential for use in harsh operating conditions.

关键词： intercalatedα-ZrP/SIB physical film chemical film tribological properties

Allelic reprogramming of chromatin states in human early embryos

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National Science Review 2024年第03期11卷 58-71页

作者： Shenli Yuan lei gao Wenrong Tao Jianhong Zhan Gang Lu Jingye Zhang Chuanxin Zhang Lizhi Yi Zhenbo Liu Zhenzhen hou Min Dai Han Zhao Zi-Jiang Chen Jiang Liu Keliang Wu Center for Reproductive Medicine Shandong University CAS Key Laboratory of Genome Sciences and Information Collaborative Innovation Center of Genetics and Development Beijing Institute of Genomicsand China National Center for BioinformationChinese Academy of Sciences University of Chinese Academy of Sciences CUHK-SDU Joint Laboratory on Reproductive Genetics School of Biomedical Sciences the Chinese University of Hong Kong Key Laboratory of Reproductive Endocrinology of the Ministry of Education Shandong University Center for Reproductive Medicine Ren Ji Hospital School of Medicine Shanghai Jiao Tong University CAS Center for Excellence in Animal Evolution and Genetics Chinese Academy of Sciences

The reprogramming of parental epigenomes in human early embryos remains elusive. To what extent the characteristics of parental epigenomes are conserved between humans and mice is currently unknown. Here,we mapped parental haploid epigenomes using human parthenogenetic and androgenetic embryos. Human embryos have a larger portion of genome with parentally specific epigenetic states than mouse *** allelic patterns of epigenetic states for orthologous regions are not conserved between humans and mice. Nevertheless, it is conserved that maternal DNA methylation and paternal H3K27me3 are associated with the repression of two alleles in humans and mice. In addition, for DNA-methylation-dependent imprinting, we report 19 novel imprinted genes and their associated germline differentially methylated regions. Unlike in mice, H3K27me3-dependent imprinting is not observed in human early ***, allele-specific epigenomic reprogramming is different in humans and mice.

关键词： human embryo epigenetics reprogramming DNA methylation H3K27me3 chromatin accessibility

Regulating photothermal properties of near-infrared croconaine dyes by supramolecular assembly

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Nano Research 2024年第9期17卷 8560-8570页

作者： Yangge Ren Yue Lu Juanjuan gao Yi Ding Bo Zhu Xinyu hou Lin Jia Department of Polymer Materials School of Materials Science and EngineeringShanghai UniversityShanghai 200444China Department of Electronic Information Materials School of Materials Science and EngineeringShanghai UniversityShanghai 200444China

The photochemical and photophysical properties of near-infrared(NIR)dyes are significantly influenced by their aggregation state and mesoscopic ***,beyond chemical synthesis,the regulation mechanisms for the properties of NIR dyes,particularly with respect to photothermal properties of the aggregates,are not yet fully ***,we investigate the photothermal behaviors of croconaine-based(CroA)NIR dyes containing dipeptide or amino acids *** introduction of hydrogen bonding promotesπ-πstacking of croconaine center,which can efficiently regulate aggregation states and assembly structures in *** laser irradiation,CroA aggregates undergo aggregation-dissociation transition,the in-situ monomer generation process regulates two parameters of photothermal performance:heating rates and plateau photothermal *** study reveals the regulation effect of non-covalent bonding interactions on CroA aggregates,highlighting supramolecular assembly strategy not only facilitates to construct of photothermal nanomaterials with well-defined structures,but also provides an alternative and effective method for regulating photothermal performance of NIR dyes.

关键词： croconaine dye hydrogen bonding photothermal performance supramolecular assembly chirality

Cable-driven legged landing gear for unmanned helicopter:Prototype design,optimization and performance assessment

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Science China(Technological Sciences) 2024年第4期67卷 1196-1214页

作者： TIAN BaoLin gao HaiBo YU HaiTao SHAN HaoMin hou JunChen YU HongYing DENG ZongQuan State Key Laboratory of Robotics and System Harbin Institute of TechnologyHarbin 150001China China Academy of Aerospace Science and Innovation Beijing 100048China

Unmanned helicopters equipped with adaptive landing gear will dramatically extend their application especially in dealing with challenging *** study presents a novel cable-driven legged landing gear(CLG)with differential transmission for unmanned helicopters in complex landing *** obtain the preferred configuration of the legged mechanism,a multi-objective optimization framework for the CLG is constructed by concurrently considering terrain adaptability,landing stability and reasonable linkage of internal *** non-dominated sorting genetic algorithmⅡis employed to numerically acquire the optimal scale parameters that guide the mechanical design of the *** unmanned helicopter prototype equipped with the devised CLG is developed with key performance *** results show that the devised CLG can provide energy-efficient support over uneven terrains(totally driven torque demand less than 0.1 N m)in quasi-static landing tests,and favorable terrain adaptability(posture fluctuation of the fuselage less than±1°)in unknown slope landing *** exhibited merits give the proposed CLG the potential to enhance the landing performance of future aircraft in extreme environments.

关键词： unmanned helicopter adaptive landing gear experimental verification

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微机距离保护仿真系统的设计与实现

电力自动化设备 2007年第9期27卷 88-90页

作者：邹贵彬高厚磊江世芳山东大学电气工程学院山东济南250061

根据微机距离保护的工作原理和基本组成,设计了微机距离保护动态仿真系统。按照模块化设计,系统由基于EMTDC的故障暂态计算模块、启动元件模块、傅里叶算法模块、选相元件模块、阻抗继电器模块和显示模块6部分组成。仿真系统将数据格式... 详细信息

根据微机距离保护的工作原理和基本组成,设计了微机距离保护动态仿真系统。按照模块化设计,系统由基于EMTDC的故障暂态计算模块、启动元件模块、傅里叶算法模块、选相元件模块、阻抗继电器模块和显示模块6部分组成。仿真系统将数据格式转换后的故障暂态计算结果作为距离保护动态仿真程序的输入量,通过对输入量进行逐点计算,能同步逐点显示出继电器的测量阻抗和其他各种仿真结果。仿真实例表明,该动态仿真系统既能较好地仿真距离保护在不同工况下的动作行为,为分析距离保护提供依据,而且还可以作为一种有效的软件工具用于继电保护的开发和教学。

关键词：距离保护动态仿真继电保护 LabVIEW