检索结果-南通市图书馆

Anthrax lethal toxin and tumor necrosis factor-a synergize on intestinal epithelia to induce mouse death

在线全文

学校读者我要写书评

暂无评论

Protein & Cell 2024年第2期15卷 135-148页

作者： Xinhe gao Teng Teng yifei Liu Tingting Ai Rui Zhao Yilong Fu Peipei Zhang Jiahuai Han Yingying Zhang State Key Laboratory of Cellular Stress Biology School of Life SciencesFaculty of Medicine and Life SciencesXiamen UniversityXiamen 361102China Research Unit of Cellular Stress of CAMS Xiang'an Hospital of Xiamen UniversityCancer Research Center of Xiamen UniversitySchool of MedicineFaculty of Medicine and Life SciencesXiamen UniversityXiamen 361102China Laboratory Animal Center Faculty of Medicine and Life SciencesXiamen UniversityXiamen 361102China

Bacillus anthracis lethal toxin(LT)is a determinant of lethal *** function in myeloid cells is required for bacterial dissemination,and LT itself can directly trigger dysfunction of the cardiovascular *** interplay between LT and the host responses is important in the pathogenesis,but our knowledge on this interplay remains *** necrosis factor-a(TNF-a)is a pleiotropic pro-inflammatory cytokine induced by bacterial *** LT accumulates and cytokines,predominantly TNF,amass during *** infection,co-treatment of TNF+LT in mice was used to mimic in vivo conditions for LT to function in inflamed *** marrow transplantation and genetically engineered mice showed unexpectedly that the death of intestinal epithelial cells(IECs)rather than that of hematopoietic cells led to LT+TNF-induced *** of p38a mitogen-activated protein kinase(MAPK)signaling by LT in IECs promoted TNF-induced apoptosis and necroptosis of IECs,leading to intestinal damage and mouse ***,p38a inhibition by LT enhanced TNF-mediated cell death in human colon epithelial HT-29 *** intestinal damage is one of the leading causes of lethality in anthrax patients,the IEC damage caused by LT+TNF would most likely be a mechanism underneath this clinical manifestation and could be a target for interventions.

关键词： lethal toxin TNF p38a intestinal epithelial cell cell death

Delimiting the landscape of neuronal granules

在线全文

学校读者我要写书评

暂无评论

Delimiting the landscape of neuronal granules

Fabrication of MXene-Bi_(2)WO_(6)heterojunction by Bi_(2)Ti_(2)O_(7)hinge for extraordinary LED-light-driven photocatalytic performance

2021年全国生物相分离和相变学术研讨会

作者： Pilong Li yifei gao Lingyao Wang Siyue Yuan School of life sciences Tsinghua University

Neurons are among the most polarized cell types in *** sorting and delivery of mRNAs are essential for the well being of *** are enormous assortment of RNP granules,called neuronal granules,which can partially achieve these *** is pivotal to delimit the composition of and dissect the assembly mechanism of neuronal *** this talk,I will discuss our initial effort towards tackling these questions.

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Nano Research 2024年第6期17卷 4729-4736页

作者： Zhiwen Li Liangliang Xu Zaheer Ud Din Babar Ali Raza yifei Zhang Xinrui Gu Yu-Xin Miao Zhen Zhao gao Li Institute of Catalysis for Energy and Environment College of Chemistry and Chemical EngineeringShenyang Normal UniversityShenyang 110034China State Key Laboratory of Catalysis Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023China Scuola Superiore Meridionale(SSM) University of Naples Federico IILargo S.Marcellino1080138Italy Department of Chemical and Biomolecular Engineering Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141Republic of Korea University of Chinese Academy of Sciences Beijing 100049China

Heterojunction composites with intimate interfaces can shorten the diffusion distance,which leads to a shorter path for photogenerated carriers,thereby increasing photocatalytic ***,we report the fabrication of Ti_(3)C_(2)-Bi_(2)WO_(6)(TC-BW)heterojunctions hinged by Bi_(2)Ti_(2)O_(7)joints via an in situ hydrothermal reaction of Ti_(3)C_(2)in the presence of Na_(2)WO_(4)and Bi(NO_(3))_(3).The TC-BW was characterized using X-ray diffraction(XRD),scanning transmission electron microscopy(STEM),and Raman ***-BW showed superior photocatalytic activity(productivity over 15TC-WB reaches up to 5.0 mmolreacted BA·gcat.^(−1)·h^(−1))in the oxidation of benzyl alcohol using light-emitting diode(LED)light,arising from the surface defects and intimate heterojunction interface between the Ti_(3)C_(2)MXene and Bi_(2)WO_(6)***-BW heterojunctions provide an enhanced separation efficiency of photogenerated charges,which in turn yields superior photocatalytic ***,it is well substantiated by density functional theory(DFT)*** summary,this study elucidates the preparation of heterojunction composites with intimate interfaces for highly efficient photooxidation.

关键词： MXene-Bi_(2)WO_(6) heterojunction LED-light-driven photocatalysis Bi_(2)Ti_(2)O_(7) photooxidation

Optimization of inter-seasonal nitrogen allocation increases yield and resource-use efficiency in a water-limited wheat-maize cropping system in the North China Plain

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Crop Journal 2024年第3期12卷 907-914页

作者： Xiaonan Zhou Chenghang Du Haoran Li Zhencai Sun yifei Chen Zhiqiang gao Zhigan Zhao Yinghua Zhang Zhimin Wang Ying Liu College of Agronomy and Biotechnology China Agricultural UniversityBeijing 100193China College of Information and Electrical Engineering China Agricultural UniversityBeijing 100193China Ministerial and Provincial Co-Innovation Centre for Endemic Crops Production with High-Quality and Efficiency in Loess Plateau Taigu 030801ShanxiChina

Winter wheat–summer maize cropping system in the North China Plain often experiences droughtinduced yield reduction in the wheat season and rainwater and nitrogen(N)fertilizer losses in the maize *** study aimed to identify an optimal interseasonal water-and N-management strategy to alleviate these *** ratios of allocation of 360 kg N ha^(-1)between the wheat and maize seasons under one-time presowing root-zone irrigation(W0)and additional jointing and anthesis irrigation(W2)in wheat and one irrigation after maize sowing were set as follows:N1(120:240),N2(180:180),N3(240:120)and N4(300:60).The results showed that under W0,the N3 treatment produced the highest annual yield,crop water productivity(WPC),and nitrogen partial factor productivity(PFPN).Increased N allocation in wheat under W0 improved wheat yield without affecting maize yield,as surplus nitrate after wheat harvest was retained in the topsoil layers and available for the subsequent *** W2,annual yield was largest in the N2 *** risk of nitrate leaching increased in W2 when N application rate in wheat exceeded that of the N2 treatment,especially in the wet *** to W2N2,the W0N3 maintained 95.2%grain yield over two *** WPCwas higher in the W0 treatment than in the W2 ***,following limited total N rate,an appropriate fertilizer N transfer from maize to wheat season had the potential of a“triple win”for high annual yield,WPCand PFPN in a water-limited wheat–maize cropping system.

关键词： Cropping system Water-saving irrigation North China Plain Nitrogen optimization Sustainable intensification

基于频率分集阵列小埋体检测三维形貌成像方法

在线全文

学校读者我要写书评

暂无评论

郑州航空工业管理学院学报 2024年第2期42卷 72-78页

作者：周鹏王丽莹李鹏飞布锦钶吕子悦高艺蜚张文理赵青郑州航空工业管理学院电子信息学院河南郑州450046 郑州航空工业管理学院航空航天电子信息技术河南省协同创新中心河南郑州450046 郑州航空工业管理学院河南省通用航空技术重点实验室河南郑州450046

频率分集阵列(Frequency Diverse Array,简称FDA)在埋体管线的探测识别与成像中具有很大优势,利用其灵活的波束控制和信号处理性能,能够摆脱传统阵列发射信号限制,灵活接收和处理复杂信号。通过发出窄带信号进而获得宽带信号探测参数,... 详细信息

频率分集阵列(Frequency Diverse Array,简称FDA)在埋体管线的探测识别与成像中具有很大优势,利用其灵活的波束控制和信号处理性能,能够摆脱传统阵列发射信号限制,灵活接收和处理复杂信号。通过发出窄带信号进而获得宽带信号探测参数,大大降低操作成本,实现高效率、高精度、高性价比三维立体成像。现如今埋体管线探测成为城市发展中不可避免的痛点,小埋藏体检测成像更是难点问题。文章提出一种基于多进多出技术(Multiple-Input Multiple-Output,简称MIMO)的频率分集阵列三维合成孔径雷达(3D-FDA-MAR)成像方法,并将MIMO阵列引入频率分集阵列实现三维成像,建立了MIMO-FDA三维形貌成像模型。该多进多出频率分集阵列在三维空间中能够随平台运动而运动,在沿航向处得到综合孔径,根据切航向阵列能够获得仿真频率分集阵列平面,从而得到目标物成像的三维立体效果,实现精准定位,全空间透视探测,智能3D成像,小埋藏体的精准检测诊断。

关键词：频率分集阵列三维成像埋体管线合成孔径雷达多进多出压缩感知成像算法

追诉时效争议问题研究——以刑法和刑事诉讼法的协调为视角

在线全文

学校读者我要写书评

暂无评论

中国刑事法杂志 2020年第4期4卷 155-176页

作者：高翼飞最高人民检察院法律政策研究室

"追诉"对公诉案件而言,是指从立案侦查到提起公诉的过程。审判活动不受追诉时效约束。在追诉进行过程中存在追诉期限停止计算的情形。侦查机关撤销案件、检察机关作存疑不起诉、撤回起诉或者法院作出证据不足的无罪判决后发现新的证据... 详细信息

"追诉"对公诉案件而言,是指从立案侦查到提起公诉的过程。审判活动不受追诉时效约束。在追诉进行过程中存在追诉期限停止计算的情形。侦查机关撤销案件、检察机关作存疑不起诉、撤回起诉或者法院作出证据不足的无罪判决后发现新的证据并再次追诉的,应当受追诉时效约束。"立案侦查"是指对人立案,并且立案后对犯罪嫌疑人采取侦查措施。在立案侦查前逃避侦查的,计算追诉期限;但逃避侦查的状态持续到立案侦查以后的,自立案侦查之后不受追诉期限的限制。"不受追诉期限的限制"是追诉时效中止而非延长,即在法定事由消失前停止计算追诉期限。追诉期限跨越新旧刑法施行期间的,旧法施行期间适用旧法规定的追诉时效制度,新法施行期间适用新法规定的追诉时效制度。

关键词：追诉期限中止延长立案侦查溯及力

Mechanical Properties of Micro-phases along ＜001＞ Direction of Directionally Solidified Nickel-base Super-alloy by In-Situ Nano-indentation

在线全文

学校读者我要写书评

暂无评论

Mechanical Properties of Micro-phases along ＜001＞ Directio...

美国刑事审前听证程序公开及对我国的借鉴意义

“第十届中国钢铁年会”暨“第六届宝钢学术年会”

作者： Ma Yaxin Zou Yuming gao yifei Zhang Yuefei Du Yuanming Central Iron and Steel Research Institute National Analysis Center for Iron and Steel Chengdu Aeronautic Polytechnic Beijing University of Technology

In this paper,using the in-situ nano-indentation device（SPM/SEM hybrid system） to test the micro-mechanical properties of γ′ phase and eutectic γ′ phase which along ＜001＞ direction of directionally solidified nickel-base super-alloy. The hardness and modulus of the eutectic γ′ is higher than γ′ phase. For the specimen ST（without aging treatment）,the elastic modulus and hardness of the γ′ phase respectively is 110.7GPa and 1.45 GPa,the elastic modulus and hardness of the eutectic γ′ phase respectively is 171.2GPa and 3.98GPa;for the specimen W-1000（aging 1000hours）,the elastic modulus and hardness of the γ′ phase respectively is 105.4GPa and 1.35 GPa,the elastic modulus and hardness of the eutectic γ′ phase respectively is 161.5GPa and 3.85 GPa. After long-term high-temperature aging without loading,the change of the micro-mechanical properties of γ′ phase and eutectic γ′ phase which along ＜001＞ direction of directionally solidified nickel-base super-alloy is not apparent. Meanwhile the results of the FEM are in good agreement with the results of the experiments.

关键词： super-alloy in-situ nano-indentation hardness modulus

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

比较法研究 2017年第1期31卷 50-64页

作者：高一飞西南政法大学诉讼法与司法改革研究中心

美国刑事诉讼中的审前听证主要包括治安法官对可能侵害被告人宪法性权利的执法行为进行司法审查,如扣押听证、羁押听证、保释听证、预审听证,也包括审判前的陪审员选任听证等。审前听证公开有利于保障公民知情权,但有可能对被告人公正... 详细信息

美国刑事诉讼中的审前听证主要包括治安法官对可能侵害被告人宪法性权利的执法行为进行司法审查,如扣押听证、羁押听证、保释听证、预审听证,也包括审判前的陪审员选任听证等。审前听证公开有利于保障公民知情权,但有可能对被告人公正审判的利益造成不利影响。经过一系列判例,在美国逐渐形成了审前听证公开为常态、不公开为例外的规则。美国审前听证公开对我国刑事审前听证公开有重大的借鉴意义,我国应当增加刑事审前听证的法定种类、扩大听证公开的程度、赋予听证当事人以救济权、允许媒体对刑事审前听证旁听和采访。

关键词：刑事审前听证听证公开言论自由公正审判

在线全文

学校读者我要写书评

暂无评论

智慧社会中的“数字弱势群体”权利保障

江海学刊 2019年第5期 163-169页

作者：高一飞浙江工商大学法学院

"数字弱势群体"是由于数字科技的固有特征、不均衡传导以及社会既有结构等客观因素,导致权利缺失、能力不足,进而展现出地位边缘、资源匮乏、易受挫伤等特征的特定群体,可视为数字科技复杂特性、社会内在结构缺陷、虚拟空间秩序紊乱共... 详细信息

"数字弱势群体"是由于数字科技的固有特征、不均衡传导以及社会既有结构等客观因素,导致权利缺失、能力不足,进而展现出地位边缘、资源匮乏、易受挫伤等特征的特定群体,可视为数字科技复杂特性、社会内在结构缺陷、虚拟空间秩序紊乱共同作用的产物。对其权利加以保障,既是智慧社会建设的必要条件,也有利于推进弱势群体保护工作,回应"数字人权"问题。遵循平等保护与倾斜保护相结合原则、人权保障原则、共建共治共享原则,数字弱势群体的权利保障主要包括权利义务再分配、公共服务优化、权利赋能三个方面的内容。

关键词： "数字弱势群体" 智慧社会数字人权权利保障