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Screening and field application of microbial-flooding activator systems

Energy Geoscience 2024年第2期5卷 14-20页

作者： Xiutian Yao Lipeng Gai Yun Feng Runlin Zhao yang gao Yucui Zhang Chuanzhi Cui Jun Ma Zhongwei Wu Gudao Oil Production Plant Sinopec Shengli Oilfield BranchDongyingShandong257231China Sinopec Shengli Oilfield Branch Petroleum Engineering Technology Research InstituteDongyingShandong257000China School of Petroleum Engineering China University of Petroleum(East China)QingdaoShandong266580China Hubei Key Laboratory of Drilling and Production Engineering for Oil and Gas Yangtze UniversityWuhan430100China School of Petroleum Engineering Yangtze UniversityWuhan430100China

This study aims to further enhance the oil recovery of reservoirs in the Zhong-2 Block of the Gudao Oilfield by identifying the most effective microbial-flooding activator systems and applying them in the *** began by analyzing the structure of the reservoirs'endogenous microbial communities to understand the potential impact of microbial *** was followed by determining commonly used activator systems based on their abilities to stimulate oil-displacement functional *** laboratory experiments on oil displacement efficiency and sweep characteristics,we determined the optimal activator injection method(injection ratio)and the requisite bacterial concentration for maximal microbial-flooding ***,we selected the optimal activator systems and applied them to field *** findings suggest the target block is highly receptive to *** terms of performance,the activator systems ranked as No.3>No.4>No.1>***,a deep activator system,when compared to the top-performing No.3 system,exhibited a higher bacterial concentration peak and longer peaking *** oil displacement effects were observed at a 1:4 vol ratio between the No.3 activator and deep activator systems,with bacterial concentrations of up to 106 cells/mL or *** tests with the selected activator systems,following a specific injection protocol,demonstrated a notable increase in oil production and a reduction in water cut.

关键词： Zhong-2 Block of Gudao Oilfield Microbial flooding Laboratory experiment Screening of activator system Field application

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DNA framework signal amplification platform-based highthroughput systemic immune monitoring

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Signal Transduction and Targeted Therapy 2024年第3期9卷 1115-1131页

作者： Ye Chen Xingyu Chen Bowen Zhang Yuxin Zhang Songhang Li Zhiqiang Liu yang gao Yuxuan Zhao Lin Yan Yi Li Taoran Tian Yunfeng Lin State Key Laboratory of Oral Diseases National Center for StomatologyNational Clinical Research Center for Oral DiseasesWest China Hospital of StomatologySichuan UniversityChengdu 610041 SichuanPR China Department of Prosthodontics Tianjin Stomatological HospitalSchool of MedicineNankai UniversityTianjin 300041PR China Department of Laboratory Medicine West China HospitalSichuan UniversityChengdu 610041 SichuanPR China Sichuan Provincial Engineering Research Center of Oral Biomaterials Chengdu 610041 SichuanChina

Systemic immune monitoring is a crucial clinical tool for disease early diagnosis,prognosis and treatment planning by quantitative analysis of immune ***,conventional immune monitoring using flow cytometry faces huge challenges in large-scale sample testing,especially in mass health screenings,because of time-consuming,technical-sensitive and high-cost ***,the lack of high-performance detection platforms hinders the development of high-throughput immune monitoring *** address this bottleneck,we constructed a generally applicable DNA framework signal amplification platform(DSAP)based on post-systematic evolution of ligands by exponential enrichment and DNA tetrahedral framework-structured probe design to achieve high-sensitive detection for diverse immune cells,including CD4+,CD8+T-lymphocytes,and monocytes(down to 1/100μl).Based on this advanced detection platform,we present a novel high-throughput immune-cell phenotyping system,DSAP,achieving 30-min one-step immune-cell phenotyping without cell washing and subset analysis and showing comparable accuracy with flow cytometry while significantly reducing detection time and *** a proof-of-concept,DSAP demonstrates excellent diagnostic accuracy in immunodeficiency staging for 107 HIV patients(AUC>0.97)within 30 min,which can be applied in HIV infection monitoring and ***,we initially introduced promising DSAP to achieve high-throughput immune monitoring and open robust routes for point-of-care device development.

关键词： diagnosis monitoring initially

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Valorization of Camellia oleifera oil processing byproducts to value-added chemicals and biobased materials: A critical review

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Green Energy & Environment 2024年第1期9卷 28-53页

作者： Xudong Liu Yiying Wu yang gao Zhicheng Jiang Zicheng Zhao Wenquan Zeng Mingyu Xie Sisi Liu Rukuan Liu Yan Chao Suli Nie Aihua Zhang Changzhu Li Zhihong Xiao State Key Laboratory of Utilization of Woody Oil Resource Hunan Academy of ForestryChangsha410004China Key Laboratory of State Forestry and Grassland Administration on Utilization Science for Southern Woody Oil Resource Hunan Academy of ForestryChangsha410004China Hunan Provincial Key Laboratory of Oils and Fats Molecular Structure and Function Changsha410004China State Key Laboratory of Separation Membranes and Membrane Processes College of ChemistryTiangong UniversityTianjin300387China College of Biomass Science and Engineering Sichuan UniversityChengdu610065China College of Mechanical Engineering and Mechanics Xiangtan UniversityXiangtan411105China

The *** oil processing industry generates large amounts of solid wastes,including *** shell(COS)and *** cake(COC).Distinct from generally acknowledged lignocellulosic biomass(corn stover,bamboo,birch,etc.),Camellia wastes contain diverse bioactive substances in addition to the abundant lignocellulosic components,and thus,the bioreﬁnery utilization of *** processing byproducts involves complicated processing *** reviewﬁrst summarizes various technologies for extracting and converting the main components in *** oil processing byproducts into value-added chemicals and biobased materials,as well as their potential ***,ultrasound,and Soxhlet extractions are compared for the extraction of functional bioactive components(tannin,ﬂavonoid,saponin,etc.),while solvothermal conversion and pyrolysis are discussed for the conversion of lignocellulosic components into value-added *** application areas of these chemicals according to their properties are introduced in detail,including utilizing antioxidant and anti-in-ﬂammatory properties of the bioactive substances for the speciﬁc application,as well as drop-in chemicals for the substitution of unrenewable fossil fuel-derived *** addition to chemical production,biochar fabricated from COS and its applications in theﬁelds of adsorption,supercapacitor,soil remediation and wood composites are comprehensively reviewed and ***,based on the compositions and structural characteristics of *** byproducts,the development of full-component valorization strategies and the expansion of the appli-cationﬁelds are proposed.

关键词： Camellia oleifera shell Camellia oleifera cake Value-added chemicals Bioactive components Biobased materials

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通用人工智能提供者内容审查注意义务的证成

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东方法学 2024年第1期 189-200页

作者：高阳上海对外经贸大学

通用人工智能可自发或受用户操控被动生成有害信息,它的提供者作为新型的网络内容提供者,负有数字内容“守门人”职责,同时负有网络空间的安全保护义务,应承担内容审查的注意义务,从而预防有害信息的侵权风险。“以数据为中心”的内容... 详细信息

通用人工智能可自发或受用户操控被动生成有害信息,它的提供者作为新型的网络内容提供者,负有数字内容“守门人”职责,同时负有网络空间的安全保护义务,应承担内容审查的注意义务,从而预防有害信息的侵权风险。“以数据为中心”的内容生产方式和算法黑箱效应降低了通用人工智能提供者对内容的管控力,导致对生成内容的普遍审查难以被实现。应针对有害信息,结合内容生产场景、提供者风险预见能力差异化构建内容审查的注意义务。该注意义务以技术性审查为标准,提供者采取符合技术特点的内容审查机制,便应当认定履行了相关义务。

关键词：通用人工智能有害信息注意义务信息内容安全网络内容提供者内容审查义务

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亚当·博登斯坦对亚里士多德主义本原学说的批判

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科学技术哲学研究 2024年第4期041卷 101-107页

作者：高洋西北大学科学史高等研究院

亚当·博登斯坦是16世纪早期帕拉塞尔苏斯主义者中最为杰出的人物之一。博登斯坦继承了帕拉塞尔苏斯基于炼金术研究与实践而对古代哲学与医学作出的批评，在他编辑出版的帕拉塞尔苏斯著作《论长生》(1562)的长篇献词中，他对亚里士多德... 详细信息

亚当·博登斯坦是16世纪早期帕拉塞尔苏斯主义者中最为杰出的人物之一。博登斯坦继承了帕拉塞尔苏斯基于炼金术研究与实践而对古代哲学与医学作出的批评，在他编辑出版的帕拉塞尔苏斯著作《论长生》(1562)的长篇献词中，他对亚里士多德主义本原学说进行了详尽的批判。博登斯坦辩护了一种与现代经验主义与实证主义相近的立场，他认为亚里士多德的本原(质料、形式及缺乏)既无法通过感官察觉，也无法借助炼金术实验证明；此外，亚里士多德的理论也无法与基督教信仰一致。与之相对，帕拉塞尔苏斯的三本原学说能够满足所有这些要求，因此它必定比亚里士多德虚构的本原更加优越。

关键词：亚当·博登斯坦亚里士多德帕拉塞尔苏斯本原

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木雅语东、西部方言的致使结构

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民族语文 2024年第2期 46-54页

作者：高扬重庆工商大学国际商学院重庆400067

本文从类型学视角出发,分别对木雅语两个方言词汇型、形态型和分析型三种类型的致使结构进行描写、分析及比较。此外,对西部方言中动词词根清声母与鼻浊声母交替而产生的动词及物性变化现象进行了深入分析。通过该现象与临近语言及古汉... 详细信息

本文从类型学视角出发,分别对木雅语两个方言词汇型、形态型和分析型三种类型的致使结构进行描写、分析及比较。此外,对西部方言中动词词根清声母与鼻浊声母交替而产生的动词及物性变化现象进行了深入分析。通过该现象与临近语言及古汉语不及物前缀^(*)m-的对比分析,认为木雅语西部方言中看似内部屈折形式的形态型致使,有可能是通过添加反致使前缀,从及物到不及物的反致使现象。

关键词：木雅语东部方言西部方言使动范畴反致使现象

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Construction and validation of a risk-prediction model for anastomotic leakage after radical gastrectomy: A cohort study in China

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Laparoscopic, Endoscopic and Robotic Surgery 2024年第1期7卷 34-43页

作者： Jinrui Wang Xiaolin Liu Hongying Pan Yihong Xu Mizhi Wu Xiuping Li yang gao Meijuan Wang Mengya Yan Nursing Department Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016China Department of General Surgery Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310016China School of Nursing Zhejiang Chinese Medical UniversityHangzhou 310053China

Objectives:Anastomotic leakage(AL)stands out as a prevalent and severe complication following gastric cancer *** frequently precipitates additional serious complications,significantly influencing the overall survival time of *** study aims to enhance the risk-assessment strategy for AL following gastrectomy for gastric ***:This study included a derivation cohort and validation *** derivation cohort included patients who underwent radical gastrectomy at Sir Run Run Shaw Hospital,Zhejiang University School of Medicine,from January 1,2015 to December 31,*** evidence-based predictor questionnaire was crafted through extensive literature review and panel *** on the questionnaire,inpatient data were collected to form a model-derivation *** cohort underwent both univariate and multivariate analyses to identify factors associated with AL events,and a logistic regression model with stepwise regression was developed.A 5-fold cross-validation ensured model *** validation cohort included patients from August 1,2021 to December 31,2021 at the same *** the same imputation method,we organized the validation-queue *** then employed the risk-prediction model constructed in the earlier phase of the study to predict the risk of AL in the subjects included in the validation *** compared the predictions with the actual occurrence,and evaluated the external validation performance of the model using model-evaluation indicators such as the area under the receiver operating characteristic curve(AUROC),Brier score,and calibration ***:The derivation cohort included 1377 patients,and the validation cohort included 131 *** independent predictors of AL after radical gastrectomy included age65 y,preoperative albumin<35 g/L,resection extent,operative time240 min,and intraoperative blood loss90 *** predictive model exhibited a solid AUROC of 0.750(95%CI:0.694e0.806;p<0.001)with a Br

关键词： Stomach neoplasms Anastomotic leak Risk factors Prediction model Risk assessment

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Efficacy of acupoint injection in the treatment of chronic eczema and its influence on peripheral blood T cells

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World Journal of Clinical Cases 2024年第17期12卷 3019-3026页

作者： Hui-Hui Gan gao yang Ting-Ting Shen Department of Dermatology Jinshan Hospital of Fudan UniversityShanghai 201508China

BACKGROUND Chronic eczema significantly impacts daily life,social interactions,and quality of life;however,no curative treatment has been *** To determine the clinical efficacy of acupoint injection for chronic eczema and its influence on peripheral blood T *** Eighty patients with chronic eczema treated at our hospital between June 2022 and March 2023 were randomly assigned to a control group(n=40),which received conventional Western medicine treatment,or an observation group(n=40),which received routine Western medicine treatment plus acupoint injection of triamcinolone *** and adverse reaction rates,as well as differences in the levels of serum cytokines IFN-γ,IL-2,IL-4,and IL-10 before and after treatment were *** No difference in overall response rates were found between the observation and control groups(100%vs 90%,respectively;P>0.05);however,the observation group had a higher marked response rate than the control group(87.5%vs 52.5%;P0.05).The observation group exhibited higher post-treatment INF-γand IL-2 but lower IL-4 levels than the control group(P0.05).CONCLUSION Acupoint injection of triamcinolone acetonide is safe and effective in treating chronic *** therapeutic mechanism is related to the regulation of peripheral blood T cell levels,inhibition of inflammatory reactions,and mitigation of immune imbalance.

关键词： Eczema Acupoint injection T cells Immune imbalance

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BambooBase:A comprehensive database of bamboo omics and systematics

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Molecular Plant 2024年第5期17卷 682-685页

作者： Yun-Long Liu Shu-yang gao Guihua Jin Meng-Yuan Zhou Qijuan gao Cen Guo Yi-Zhou yang Liang-Zhong Niu Enhua Xia Zhen-Hua Guo Peng-Fei Ma De-Zhu Li Germplasm Bank of Wild Species&Yunnan Key Laboratory of Crop Wild Relatives Omics Kunming Institute of BotanyChinese Academy of SciencesKunmingYunnan 650201China Kunming College of Life Science University of Chinese Academy of SciencesKunmingYunnan 650201China State Key Laboratory of Tea Plant Biology and Utilization Anhui Agricultural UniversityHefeiAnhui 230036China School of Computer and Artificial Intelligence Hefei Normal UniversityHefeiAnhui 230061China Key Laboratory for Plant Diversity and Biogeography in East Asia Kunming Institute of BotanyChinese Academy of SciencesKunmingYunnan 650201China

Dear Editor,Bamboos(Bambusoideae,Poaceae)are of significant economic and ecological importance,supporting billions of people and contributing to international trade(Wu et al.,2023).They play a crucial role in carbon fixation and support a multitude of other species including the giant panda(Clark et al.,2015).Since the release of the first draft genome of moso bamboo(Phyllostachys edulis)(Peng et al.,2013),there has been a notable increase in the sequencing,assembly,and annotation of diverse bamboo genomes(Guo et al.,2019;Zheng et al.,2022;Ma et al.,2024).An existing resource for bamboo genomics,BambooGDB(Zhao et al.,2014),provides information based on the individual draft reference genome of moso *** is needed,however,is a resource reinforcing multiple genome assemblies in Bambusoideae to enable researchers to unravel the evolutionary history of chromosomes and genes through cladespecific comparative genomic ***,we present BambooBase(https://***/),a newly developed web-based database designed to provide a seamless user experience for bamboo omics and systematics.

关键词： enable supporting Bamboo

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Erratum to: Dynamic ocean inverse modeling based on differentiable rendering

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Computational Visual Media 2024年第3期10卷 609-609页

作者： Xueguang Xie yang gao Fei Hou Aimin Hao Hong Qin State Key Lab of Virtual Reality Technology and Systems Beihang UniversityBeijing 100191China Qingdao Research Institute Beihang UniversityQingdao 266100Chinaand Peng Cheng LabShenzhen 518000China SKLCS Institute of SoftwareChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China Department of Computer Science Stony Brook University(SUNY at Stony Brook)Stony BrookNew York 11794-2424USA

Erratum to Xueguang Xie,yang gao,Fei Hou,Aimin Hao&Hong *** ocean inverse modeling based on differentiable *** Visual Media Vol.10,No.2,279–294,***://doi10.1007/s41095-023-0338-4 The authors apologize for a hidden error in the *** is that the images in Figs.14(a)and 14(d)were mistakenly presented as left–right mirror *** authors have flipped them to ensure that the figures now correspond correctly with others in the subfigures(b,c,e,f).The accurate version of Fig.14 is provided as below.

关键词： ocean images inverse

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