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Generating diverse clothed 3D human animations via a generative model

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Computational Visual Media 2024年第2期10卷 261-277页

作者： Min Shi Wenke Feng lin gao Dengming Zhu School of Control and Computer Engineering North China Electric Power UniversityBeijing 102206China Institute of Computing Technology Chinese Academy of SciencesBeijing 100190China

Data-driven garment animation is a current topic of interest in the computer graphics *** approaches generally establish the mapping between a single human pose or a temporal pose sequence,and garment deformation,but it is difficult to quickly generate diverse clothed human *** address this problem with a method to automatically synthesize dressed human animations with temporal consistency from a specified human motion *** the heart of our method is a twostage ***,we first learn a latent space encoding the sequence-level distribution of human motions utilizing a transformer-based conditional variational autoencoder(Transformer-CVAE).Then a garment simulator synthesizes dynamic garment shapes using a transformer encoder-decoder *** the learned latent space comes from varied human motions,our method can generate a variety of styles of motions given a specific motion *** means of a novel beginning of sequence(BOS)learning strategy and a self-supervised refinement procedure,our garment simulator is capable of efficiently synthesizing garment deformation sequences corresponding to the generated human motions while maintaining temporal and spatial *** verify our ideas *** is the first generative model that directly dresses human animation.

关键词： Transformer garment animation conditional variational autoencoder(CVAE) computer graphics

Strain-promoted S-arylation and alkenylation of sulfinamides using arynes and cyclic alkynes

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Science China Chemistry 2024年第3期67卷 928-935页

作者： Xi Zou Boming Shen gao-lin Li Qian Liang Yanhua Ouyang Binghe Yang Peiyuan Yu Bing gao State Key Laboratory of Chemo/Bio-Sensing and Chemometrics College of Chemistry and Chemical EngineeringInstitute of Chemical Biology and NanomedicineHunan UniversityChangsha 410082China Department of Chemistry and Shenzhen Grubbs Institute Guangdong Provincial Key Laboratory of CatalysisSouthern University of Science and TechnologyShenzhen 518055China

The conversion of commercially available chiral sulfinamides into pharmaceutically useful chiral sulfoximines via direct SIVfunctionalization is synthetically attractive but challenging due to the competitive reaction of N-functionalization. Herein, we disclose a novel strain-release strategy to access stereospecific and chemoselective SIV-arylation and alkenylation of sulfinamides using arynes and strained cyclic alkynes. This method tolerates an unprecedented chemical diversity of functional groups attached to the nitrogen center(N-R). The origin of the high SIV-selectivity is elucidated by density functional theory calculations, suggesting a stepwise mechanism for the aryne substrates and a concerted mechanism for the cyclic alkynes.

关键词： arylation alkenylation sulfoximines sulfinamides arynes

Unraveling the hydraulic properties of loess for landslide prediction:A study on variations in loess landslides in Lanzhou,Dingxi,and Tianshui,China

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China Geology 2024年第2期7卷 291-302页

作者： gao-chao lin Wei Liu Xing Su School of Civil and Environmental Engineering University of New South WalesSydneyNSW 2052Australia Institute of Transportation Inner Mongolia UniversityHohhot 010070China Institute of Geological Hazards Prevention Gansu Academy of SciencesLanzhou 730000China

Loess has distinctive characteristics,leading to frequent landslide disasters and posing serious threats to the lives and properties of local re *** involvement of water repre sents a critical factor in inducing loess *** study focuses on three neighboring cities sequentially situated on the Loess Plateau along the direction of aeolian deposition of loess,namely Lanzhou,Dingxi,and Tianshui,which are densely populated and prone to landslide *** variations in hydraulic properties,including water retention capacity and permeability,are investigated through Soil Water Characteristic Curve(SWCC)test and hydraulic conductivity *** experimental findings revealed that Tianshui loess exhibited the highest water retention capacity,followed by Dingxi loess,while Lanzhou loess demonstrated the lowest water retention ***,the results for the saturated permeability coefficient were found to be the opposite:Tianshui loess showed the lowest permeability,whereas Lanzhou loess displayed the highest *** results are supported and analyzed by scanning electron microscopy(SEM)*** addition,the water retention capacity is mathematically expressed using the van Genuchten model and extended to predict unsaturated hydraulic properties of *** experimental results exhibit a strong accordance with one another and align with the regional distribution patterns of disasters.

关键词： Loess Landslide Hydraulic properties Water retention capacity and permeability Soil Water Characteristic Curve(SWCC) Hydraulic conductivity Van Genuchten model Hydrogeological engineering Geological hazards prevention engineering

Combined preoperative albumin bilirubin score and hepatectomy percentage for evaluate the liver regeneration after partial hepatectomy

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World Journal of Gastroenterology 2024年第40期30卷 4376-4379页

作者： gao-lin Wen Jing-lin Wang Department of Hepatobiliary Surgery The Affiliated Drum Tower Hospital of Nanjing University of Chinese MedicineNanjing 210008Jiangsu ProvinceChina Division of Hepatobiliary and Transplantation Surgery Department of General SurgeryNanjing Drum Tower HospitalNanjing 210008Jiangsu ProvinceChina

Surgical resection is a pivotal therapeutic approach for addressing hepatic space-occupying lesions,with liver volume restoration and hepatic functional recovery being crucial for assessing surgical *** preoperative albumin-bilirubin(ALBI)score,encompassing serum albumin and bilirubin levels,can be determined via blood analysis,effectively mitigating human error and providing an accurate depiction of liver *** hepatectomy ratio,which is the proportion of the liver volume removed to the total liver volume,is critical in preserving an adequate liver tissue volume to ensure postoperative hepatic functional compensation,minimize surgical complications,and reduce mortality *** the preoperative ALBI score and hepatectomy ratio aids surgeons in assessing the optimal timing and extent of partial *** introduction of preoperative albumin bilirubin score and hepatectomy percentage is beneficial for the surgeons to evaluate the timing and magnitude of partial liver resection.

关键词： Liver regeneration Partial hepatectomy Preoperative albumin bilirubin score Hepatectomy percentage

Optimized parameters of downhole all-metal PDM based on genetic algorithm

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Petroleum Science 2024年第4期21卷 2663-2676页

作者： Jia-Xing Lu ling-Rong Kong Yu Wang Chao Feng Yu-lin gao China University of Geosciences (Beijing) Key Laboratory on Deep Geo-Drilling Technology of Ministry of Natural Resources

Currently, deep drilling operates under extreme conditions of high temperature and high pressure,demanding more from subterranean power motors. The all-metal positive displacement motor, known for its robust performance, is a critical choice for such drilling. The dimensions of the PDM are crucial for its performance output. To enhance this, optimization of the motor's profile using a genetic algorithm has been undertaken. The design process begins with the computation of the initial stator and rotor curves based on the equations for a screw cycloid. These curves are then refined using the least squares method for a precise fit. Following this, the PDM's mathematical model is optimized, and motor friction is assessed. The genetic algorithm process involves encoding variations and managing crossovers to optimize objective functions, including the isometric radius coefficient, eccentricity distance parameter,overflow area, and maximum slip speed. This optimization yields the ideal profile parameters that enhance the motor's output. Comparative analyses of the initial and optimized output characteristics were conducted, focusing on the effects of the isometric radius coefficient and overflow area on the motor's performance. Results indicate that the optimized motor's overflow area increased by 6.9%, while its rotational speed reduced by 6.58%. The torque, as tested by Infocus, saw substantial improvements of38.8%. This optimization provides a theoretical foundation for improving the output characteristics of allmetal PDMs and supports the ongoing development and research of PDM technology.

关键词： Positive displacement motor Genetic algorithm Profile optimization Matlab programming Overflow area

Carbon capture in power sector of China towards carbon neutrality and its comparison to renewable power

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Fundamental Research 2024年第4期4卷 916-925页

作者： Sheng Li lin gao Song He Dongtai Yang Chaowei Wang Yawen Zheng School of mechanical engineering Beijing Institute of TechnologyBejing 100081China Laboratory of Integrated Energy System and Renewable Eery Institute of Engineering ThemophysicsChinese Academyof SciencesBejing0010China

CO_(2)capture from coal power plants is an important and necessary solution to realizing carbon neutrality in China,but ccs demonstration deployment in power sector is far behind ***,the reduction potential of energy consumption and cost for CcS and its competitiveness to renewable powers are very important to make roadmaps and policies toward carbon *** the popular recognition that capturing CO_(2)from flue gases is technically and commercially mature,this paper notes that it has been proved to be technically feasible but far beyond technology maturity and high energy penalty leads to its immaturity and therefore causes high ***,the potential energy penalty reduction of capture is investigated thermodynamically,and future CO_(2)avoidance cost is predicted and compared to renewable power(solar PV and onshore wind power).Results show that energy penalty for CO_(2)capture can be reduced by 48%-57%.When installation capacity reaches a similar scale to that of solar PV in China(250 GW),CO_(2)capture cost in coal power plants can be reduced from the current 28-40 USs/ton to 10-20 USs/ton,and efficiency upgrade contributes to 67%-75%in cost reduction for high coal price *** China,CO_(2)capture in coal power plants can be cost competitive with solar PV and onshore wind *** it is worth noting that the importance and share of CCS role in CO_(2)emission reduction is decreasing since renewable power is already well deployed and there is still a lack of large-scale CO_(2)capture demonstrations in *** capture technologies with low energy penalties need to be developed to promote *** in this work can provide informative references for making roadmaps and policies regarding CO_(2)emission reductions that contribute towards carbon neutrality.

关键词： Carbon capture and storage Carbon neutrality Energy consumption Fluegas Renewable energy

Spatial-Temporal Analysis of Drinking Water Type of Endemic Fluorosis—China,2009–2022

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China CDC weekly 2024年第2期6卷 25-29页

作者： Lijun Zhao Zhe Li Mang Li Hongna Sun Wei Wei lin gao Qiaoshi Zhao Yang Liu Xiaohong Ji Cheng Li Jian Wang Yanhui gao Junrui Pei Center for Endemic Disease Control Chinese Center for Disease Control and PreventionHarbin Medical UniversityHarbin CityHeilongjiang ProvinceChina Key Lab of Etiology and Epidemiology Education Bureau of Heilongjiang Province(23618504)Ministry of Health of PRHarbin Medical UniversityHarbin CityHeilongjiang ProvinceChina

What is already known about this topic?Endemic fluorosis,caused by high fluoride levels in drinking water,has been a significant health issue in rural areas of China for many *** is added by this report?There has been a notable decline in the detection rate of dental fluorosis in children aged 8–12 years in drinking water fluorosis areas across the country from 2009 to *** 14 provincial-level administrative divisions are classified as low-probability clusters,Tianjin remains classified as a high-probability *** are the implications for public health practice?The current policy for preventing and controlling endemic fluorosis in China needs *** than focusing solely on regions with high incidence,there should be a shift towards monitoring and early warning of fluoride ***,local containment measures should be intensified.

关键词： intensified Spatial fluoride

Elaborately engineering of lipid nanoparticle for targeting delivery of siRNA and suppressing acute liver injury

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Chinese Chemical Letters 2024年第2期35卷 323-328页

作者： Qiu Wang Qikun Jiang Dan Li Zimeng Yang lin gao Fan Liu Chang Li Yao Feng Zhonggui He Cong Luo Jin Sun Department of Pharmaceutics Wuya College of InnovationShenyang Pharmaceutical UniversityShenyang 110016China Kangya of Ningxia Pharmaceutical Co.Ltd. Yinchuan 750000China

Small interfering RNA(siRNA)-based gene silencing has been considered as a potential therapy modality against inflammatory ***,the effective delivery of siRNA to desired destination still remains challenging due to poor stability,high molecular weight and negative ***,ionizable lipid nanoparticle(LNP)has been extensively used as vector for effective delivery of ***,we report a mannose-modified LNP(M-MC_(3) LNP@TNFα)loading tumor necrosis factorα(TNFα)siRNA for targeting liver macrophages,achieving effectively inhibit acute liver *** M-MC_(3) LNP@TNFαnot only increases the internalization of LNP by macrophages,but also enhances the gene silencing efficiency of TNFαin ***,the M-MC_(3) LNP@TNFαexhibits higher accumulation in liver of healthy mice than that of MC_(3) LNP@TNFα(un-modified LNP)owing to the targeting effect of *** expected,the M-MC_(3) LNP@TNFαsignificantly suppresses the expression of TNFαand ameliorates liver damage in acute liver injury *** a LNP targeting siRNA delivery holds great potential for the treatment of diseases associated with liver in the future.

关键词： Lipid nanoparticle Targeting siRNA delivery Acute liver injury Gene silencing Tumor necrosis factorα

An Exploration of Organizational Development in the Process of Innovation and Transformation of Pharmaceutical Enterprises-Taking X Pharmaceutical Enterprise as an Example

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Asian Journal of Social Pharmacy 2024年第1期19卷 72-80页

作者： gao lin Sun Lihua School of Business Administration Shenyang Pharmaceutical UniversityShenyang 110016China Leiyunshang Pharmaceutical Co. Ltd.Benxi 117002China

Objective To study how to promote the smooth innovation and transformation of enterprises and enhance the market competitiveness of enterprises from the perspective of human resources organization *** the wave of pharmaceutical industry reform,some entrepreneurs realize the importance of innovation and technology in the ***,domestic pharmaceutical enterprises are still in the production-oriented *** the process of transformative innovation,pharmaceutical enterprises should not only rely on the support of scientific and technological and economic forces,but also need a suitable organizational change and many excellent talents as the source of *** Through retrieving relevant literature and combined with the organizational development practice of X pharmaceutical enterprise,the organizational development model was explored in this *** and Conclusion By forming a system of strategy,organization,talent,culture and mechanism,and building an organizational development model,we can improve the organizational atmosphere and organizational efficiency in the process of enterprise innovation and transformation,so as to enhance the competitiveness of enterprises in the market.

关键词： innovation transformation organization development organizational culture personnel training