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Comparative analysis of the short and medium-term efficacy of the Da Vinci robot versus laparoscopic total mesangectomy for rectal cancer

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1681-1690页

作者： Wei-Ge gao wen Shi Xu-Chen Gong Zhi-wen Li Yiminjiang Tuoheti Department of Anorectal Surgery People’s Hospital of Xinjiang Uygur Autonomous RegionUrumqi 830001Xinjiang Uygur Autonomous RegionChina Department of Anus and Intestine Surgery Cancer Hospital of Chinese Academy of Medical SciencesBeijing 100084China

BACKGROUND The Da Vinci robot-assisted surgery technique has been widely used in laparo-scopic mesangectomy for rectal ***,the short-term efficacy of these procedures compared to traditional laparoscopic surgery remains *** purpose of this study was to compare and analyze the short-and medium-term efficacy of Da Vinci robot and laparoscopic surgery in total mesangectomy(TME)for rectal cancer,so as to provide guidance and reference for clinical *** To investigate the safety and long-term efficacy of robotic and laparoscopic total mesorectal resection for the treatment of rectal *** The clinicopathologic data of 240 patients who underwent TME for rectal cancer in the Anorectal Department of People’s Hospital of xinjiang uygur autonomous region from August 2018 to March 2023 were retrospectively *** them,112 patients underwent laparoscopic TME(L-TME)group,and 128 patients underwent robotic TME(R-TME)*** intraoperative,postoperative,and follow-up conditions of the two groups were *** The conversion rate of the L-TME group was greater than that of the R-TME group(5.4%vs 0.8%,χ^(2)=4.417,P=0.036).The complication rate of the L-TME group was greater than that of the R-TME group(32.1%vs 17.2%,χ^(2)=7.290,P=0.007).The percentage of positive annular margins in the L-TME group was greater than that in the R-TME group(7.1%vs 1.6%,χ^(2)=4.658,P=0.031).The 3-year disease-free survival(DFS)rate and overall survival(OS)rate of the L-TME group were lower than those of the R-TME group(74.1%vs 85.2%,χ^(2)=4.962,P=0.026;81.3%vs 91.4%,χ^(2)=5.494,P=0.019);in patients with American Joint Committee on Cancer stage Ⅲ DFS rate and OS rate in the L-TME group were significantly lower than those in the R-TME group(52.5%vs 76.1%,χ^(2)=5.799,P=0.016;65.0%vs 84.8%,χ^(2)=4.787,P=0.029).CONCLUSION Compared with the L-TME group,the R-TME group had a better tumor prognosis and was more favorable for patients with rectal cancer

关键词： Rectal tumor Robots Laparoscopy Total mesangectomy Survival prognosis Retrospective analysis

Current Status and Perspectives of Dual-Atom Catalysts Towards Sustainable Energy Utilization

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Nano-Micro Letters 2024年第7期16卷 402-440页

作者： Yizhe Li Yajie Li Hao Sun Liyao gao Xiangrong Jin Yaping Li Zhi LV Lijun Xu wen Liu Xiaoming Sun State Key Laboratory of Chemical Resource Engineering Beijing Advanced Innovation Center for Soft Matter Science EngineeringCollege of ChemistryBeijing University of Chemical TechnologyBeijing 100029People’s Republic of China xinjiang Coal Mine Mechanical and Electrical Engineering Technology Research Center Xinjiang Institute of EngineeringUrumqi 830023Xinjiang Uygur Autonomous RegionPeople’s Republic of China

The exploration of sustainable energy utilization requires the imple-mentation of advanced electrochemical devices for efficient energy conversion and storage,which are enabled by the usage of cost-effective,high-performance ***,heterogeneous atomically dispersed catalysts are considered as potential candidates for a wide range of *** to conventional cata-lysts,atomically dispersed metal atoms in carbon-based catalysts have more unsatu-rated coordination sites,quantum size effect,and strong metal-support interactions,resulting in exceptional catalytic *** these,dual-atomic catalysts(DACs)have attracted extensive attention due to the additional synergistic effect between two adja-cent metal *** have the advantages of full active site exposure,high selectiv-ity,theoretical 100%atom utilization,and the ability to break the scaling relationship of adsorption free energy on active *** this review,we summarize recent research advancement of DACs,which includes(1)the comprehensive understanding of the synergy between atomic pairs;(2)the synthesis of DACs;(3)characterization meth-ods,especially aberration-corrected scanning transmission electron microscopy and synchrotron spectroscopy;and(4)electrochemical energy-related *** last part focuses on great potential for the electrochemical catalysis of energy-related small molecules,such as oxygen reduction reaction,CO_(2) reduction reaction,hydrogen evolution reaction,and N_(2) reduction *** future research challenges and opportunities are also raised in prospective section.

关键词： Dual-atom catalysts Synergetic effect Electrocatalysis Oxygen reduction reaction CO_(2)reduction reaction Hydrogen evolution reaction N2 reduction reaction

Inferring Mycobacterium Tuberculosis Drug Resistance and Transmission using Whole-genome Sequencing in a High TB-burden Setting in china

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Biomedical and Environmental Sciences 2024年第2期37卷 157-169页

作者： FAN Yu Feng LIU Dong Xin CHEN Yi Wang OU Xi Chao MAO Qi Zhi YANG Ting Ting WANG Xi Jiang HE wen Cong ZHAO Bing LIU Zhen Jiang ABULIMITI Maiweilanjiang AIHEMUTI Maimaitiaili gao Qian ZHAO Yan Lin Key Laboratory of Medical Molecular Virology(MOE/NHC/CAMS) School of Basic Medical SciencesShanghai Medical CollegeFudan UniversityShanghai 200032China National Tuberculosis Reference Laboratory Chinese Center for Disease Control and PreventionBeijing 102206China Hangzhou Red Cross Hospital Hangzhou 310005ZhejiangChina xinjiang uygur autonomous region Center for Disease Control and Prevention Urumqi 830026XinjiangChina Tuberculosis Dispensary of Kashgar Prefecture Kashgar 844099XinjiangChina

Objective china is among the 30 countries with a high burden of tuberculosis(TB)worldwide,and TB remains a public health *** Prefecture in the southern xinjiang autonomous region is considered as one of the highest TB burden regions in ***,molecular epidemiological studies of Kashgar are *** A population-based retrospective study was conducted using whole-genome sequencing(WGS)to determine the characteristics of drug resistance and the transmission *** A total of 1,668 isolates collected in 2020 were classified into lineages 2(46.0%),3(27.5%),and 4(26.5%).The drug resistance rates revealed by WGS showed that the top three drugs in terms of the resistance rate were isoniazid(7.4%,124/1,668),streptomycin(6.0%,100/1,668),and rifampicin(3.3%,55/1,668).The rate of rifampicin resistance was 1.8%(23/1,290)in the new cases and 9.4%(32/340)in the previously treated *** resistance mutations were detected more frequently in lineage 2 strains than in lineage 3 or 4 strains,respectively:18.6%vs.8.7 or 9%,P<*** estimated proportion of recent transmissions was 25.9%(432/1,668).Multivariate logistic analyses indicated that sex,age,occupation,lineage,and drug resistance were the risk factors for recent *** the low rate of drug resistance,drug-resistant strains had a higher risk of recent transmission than the susceptible strains(adjusted odds ratio,1.414;95%CI,1.023–1.954;P=0.036).Among all patients with drug-resistant tuberculosis(DR-TB),78.4%(171/218)were attributed to the transmission of DR-TB *** Our results suggest that drug-resistant strains are more transmissible than susceptible strains and that transmission is the major driving force of the current DR-TB epidemic in Kashgar.

关键词： Mycobacterium tuberculosis Whole-genome sequencing(WGS) Transmission Drug resistance xinjiang

Characterization of acute-on-chronic liver diseases: A multicenter prospective cohort study

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World Journal of Hepatology 2024年第5期16卷 809-821页

作者： Yuan-Yao Zhang Sen Luo Hai Li Shu-Ning Sun Xian-Bo Wang Xin Zheng Yan Huang Bei-Ling Li Yan-Hang gao Zhi-Ping Qian Feng Liu Xiao-Bo Lu Jun-Ping Liu Hao-Tang Ren Yu-Bao Zheng Hua-Dong Yan Guo-Hong Deng Liang Qiao Yan Zhang wen-Yi Gu Xiao-Mei Xiang Yi Zhou Yi-Xin Hou Qun Zhang Yan Xiong Cong-Cong Zou Jun Chen Ze-Bing Huang Xiu-Hua Jiang Ting-Ting Qi Yuan-Yuan Chen Na gao Chun-Yan Liu Wei Yuan Xue Mei Jing Li Tao Li Rong-Jiong Zheng Xin-Yi Zhou Jun Zhao Zhong-Ji Meng Department of Infectious Disease Institute of Biomedical ResearchRegulatory Mechanism and Targeted Therapy for Liver Cancer Shiyan Key LaboratoryHubei provincial Clinical Research Center for Precise Diagnosis and Treatment of Liver CancerTaihe HospitalHubei University of MedicineShiyan 442000Hubei ProvinceChina Department of Gastroenterology Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200120China Department of Infectious Diseases Southwest HospitalThe Third Military Medical University(Army Medical University)Chongqing 400000China Center of Integrative Medicine Beijing Ditan HospitalCapital Medical UniversityBeijing 100020China Department of Infectious Diseases Institute of Infection and ImmunologyUnion HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430020Hubei ProvinceChina Department of Infectious Diseases Hunan Key Laboratory of Viral HepatitisXiangya HospitalCentral South UniversityChangsha 110051Hunan ProvinceChina Hepatology Unit Department of Infectious DiseasesNanfang HospitalSouthern Medical UniversityGuangzhou 510515Guangdong ProvinceChina Department of Hepatology The First Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina Department of Liver Intensive Care Unit Shanghai Public Health Clinical CentreFudan UniversityShanghai 200093China Tianjin Institute of Hepatology Nankai University Second People's HospitalTianjin 300192China Infectious Disease Center The First Affiliated Hospital of Xinjiang Medical UniversityUrumqi 830054Xinjiang Uygur Autonomous RegionChina Department of Infectious Diseases and Hepatology The Second Hospital of Shandong UniversityJinan 250000Shandong ProvinceChina State Key Laboratory for Diagnosis and Treatment of Infectious Diseases Collaborative Innovation Center for Diagnosis and Treatment of Infectious DiseaseThe First Affiliated HospitalZhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina Department of Infectious Diseases The Thir

BACKGROUND Acute-on-chronic liver disease(AoCLD)accounts for the majority of patients hospitalized in the Department of Hepatology or Infectious *** To explore the characterization of AoCLD to provide theoretical guidance for the accurate diagnosis and prognosis of *** Patients with AoCLD from the Chinese Acute-on-Chronic Liver Failure(ACLF)study cohort were included in this *** clinical characteristics and outcomes,and the 90-d survival rate associated with each clinical type of AoCLD were analyzed,using the Kaplan-Meier method and the log-rank *** A total of 3375 patients with AoCLD were enrolled,including 1679(49.7%)patients with liver cirrhosis acute decompensation(LC-AD),850(25.2%)patients with ACLF,577(17.1%)patients with chronic hepatitis acute exacer-bation(CHAE),and 269(8.0%)patients with liver cirrhosis active phase(LC-A).The most common cause of chronic liver disease(CLD)was HBV infection(71.4%).The most common precipitants of AoCLD was bacterial infection(22.8%).The 90-d mortality rates of each clinical subtype of AoCLD were 43.4%(232/535)for type-C ACLF,36.0%(36/100)for type-B ACLF,27.0%(58/215)for type-A ACLF,9.0%(151/1679)for LC-AD,3.0%(8/269)for LC-A,and 1.2%(7/577)for *** HBV infection is the main cause of CLD,and bacterial infection is the main precipitant of *** most common clinical type of AoCLD is *** diagnosis and timely intervention are needed to reduce the mortality of patients with LC-AD or ACLF.

关键词： Acute-on-chronic liver disease Acute-on-chronic liver failure Liver cirrhosis Clinical features Prognosis

Chinese Expert Consensus on the Diagnosis and Treatment of Adult Dermatomyositis (2022)

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International Journal of Dermatology and Venereology 2024年第3期7卷 163-173页

作者： Hua Cao Ai-Jun Chen Yong Cui Dan-Qi Deng Xing-Hua gao Yan-Ling He Xiao-Jing Kang Hong-Zhong Jin Cheng-Xin Li Feng Li Heng-Jin Li wen-Jun Liao Xiao-Ming Liu Qian-Jin Lu Yan Lu Meng Pan Wei-Hua Pan Xiao-Ming Shu Qing Sun Ke-Yun Tang Juan Tao Yu Wang Ting Xiao Fu-Ren Zhang Han-Lin Zhang Dermatology Branch of the china International Exchange and Promotion Association for Medical and Health Care National Clinical Research Center for Dermatologic and Immunologic Diseases Department of Dermatology Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200025China Department of Dermatology First Affiliated Hospital of Chongqing Medical UniversityChongqing 400042China Department of Dermatology China-Japan Friendship HospitalBeijing 100029China Department of Dermatology the Second Affiliated Hospital of Kunming Medical UniversityKunmingYunnan 650101China Department of Dermatology the First Hospital of China Medical UniversityShenyangLiaoning 110001China Department of Dermatology Beijing Chaoyang Hospital Affiliated to Capital Medical UniversityBeijing 100020China Department of Dermatology and Venereology People’s Hospital of Xinjiang Uygur Autonomous RegionUrumqiXinjiang Uygur Autonomous Region 830001China Department of Dermatology State Key Laboratory of Complex Severe and Rare DiseasesPeking Union Medical College HospitalChinese Academy of Medical Science and Peking Union Medical CollegeBeijing 100730China Department of Dermatology First Medical CenterPLA General HospitalBeijing 100853China Department of Dermatology Hainan Hospital of PLA General HospitalSanyaHainan 572013China Department of Dermatology Xijing HospitalAir Force Medical UniversityXi’anShaanxi 710032China Department of Dermatology Huazhong University of Science and Technology Union Shenzhen HospitalShenzhenGuangdong 518052China Hospital for Skin Diseases(Institute of Dermatology) Chinese Academy of Medical Sciences and Peking Union Medical CollegeNanjingJiangsu 210042China Department of Dermatology Jiangsu Province Hospitalthe First Affiliated Hospital of Nanjing Medical UniversityNanjingJiangsu 210029China Department of Dermatology Shanghai Changzheng HospitalSecond Affiliated Hospital of Naval Medical UniversityShanghai 200003China Department of Rheumatology China-Japan Friendship HospitalBeijing 100029China Department of Dermatology Qilu Hospital of Shandong UniversityJinanShandong 250012China Department of Dermatology Union Hospital

Dermatomyositis,an idiopathic inflammatory myopathy,is characterized by distinctive skin manifestations,proximal muscle weakness,and multiple organ involvement and can be accompanied by *** provide a reference for dermatologists and clinicians in other relevant fields of clinical practice,experts from the Dermatology Branch of the china International Exchange and Promotion Association for Medical and Health Care and the National Clinical Research Center for Dermatologic and Immunologic Diseases developed this consensus on the diagnosis and treatment of adult dermatomyositis using Chinese and international literature and expert advice.

关键词： dermatomyositis adult diagnosis treatment clinical protocols expert consensus

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机器人辅助直肠癌根治术研究进展

医学综述 2024年第13期30卷 1558-1562页

作者：史文龚国杰高维鸽祝利新疆维吾尔自治区人民医院肛肠外科乌鲁木齐830000

机器人辅助手术(RAS)系统是一种新型操作系统,因其机械臂稳定性高、视野高清放大、手腕部灵活操作等特征在直肠癌根治术中广泛应用,主要包括机器人辅助经腹直肠癌根治术、机器人辅助经肛直肠癌根治术、机器人辅助经自然腔道直肠癌根治... 详细信息

机器人辅助手术(RAS)系统是一种新型操作系统,因其机械臂稳定性高、视野高清放大、手腕部灵活操作等特征在直肠癌根治术中广泛应用,主要包括机器人辅助经腹直肠癌根治术、机器人辅助经肛直肠癌根治术、机器人辅助经自然腔道直肠癌根治术、机器人荧光系统(吲哚菁绿)辅助。机械臂操作的灵活性大大提高了经腹和经肛直肠癌手术的短期疗效,RAS的荧光模式可充分且直观地识别肠管血供情况,有效减少吻合口瘘的发生,因此RAS有望成为直肠癌根治术的新一代经典治疗方案之一。

关键词：直肠癌机器人辅助手术经肛全直肠系膜切除术

Choroidal metastatic mucinous abscess caused by Pseudomonas aeruginosa:A case report

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World Journal of Clinical Cases 2021年第30期9卷 9244-9254页

作者： Zhao Li wen gao Yan-Ming Tian Yun Xiao Ophthalmic Center General Hospital of Xinjiang Military RegionUrumqi 830011Xinjiang Uygur Autonomous RegionChina PLA Eye Center General Hospital of Xinjiang Military RegionUrumqi 830011Xinjiang Uygur Autonomous RegionChina

BACKGROUND Pseudomonas aeruginosa(***)is considered a common pathogenic *** metastatic mucinous abscess caused by *** is rarely *** SUMMARY We describe the diagnostic and treatment processes of a case involving a complex choroidal space-occupying *** analyses of early clinical manifestations revealed a high possibility of choroidal melanoma,as indicated by the choroidal space-occupying lesion and *** magnetic resonance imaging results revealed no positive evidence for the diagnosis of choroidal *** exact properties of the space-occupying lesion could not be ascertained prior to ***,the lesion was subsequently confirmed as a metastatic abscess by diagnostic *** occupying lesion was found to occupy 75%of the vitreous cavity in the *** entire white viscous tissue was completely removed,and the necrotic retina was cleaned *** surgery,microbiological culture revealed mucoid ***,which was sensitive to a variety of *** bacterial infection grew and disseminated towards the outside of the *** the fifth injection,the left eye was successfully *** This is a peculiar case because a huge,local,space-occupying lesion had formed due to the dissemination of low-toxic mucinous *** in the blood from the lungs to the *** surgical removal,the bacteria were able to re-grow;thus,local infection re-spread following *** patient lost vision,but we managed to retain the full structure of the eyeball and eliminated the focus of infection.

关键词： Choroidal Choroidal metastatic mucinous abscess Pseudomonas mucinous Pseudomonas aeruginosa Infection Case report

Association between intestinal neoplasms and celiac disease:A review

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World Journal of Gastrointestinal Oncology 2021年第9期13卷 1017-1028页

作者： Man Wang Ming Yu wen-Jie Kong Mei Cui Feng gao Department of Gastroenterology People’s Hospital of Xinjiang Uygur Autonomous RegionUrumqi 830001Xinjiang Uygur Autonomous RegionChina Department of General Practice Xiangyang Central HospitalThe Affiliated Hospital of Hubei University of Arts and ScienceXiangyang 441021 Hubei ProvinceChina Department of Pathology People’s Hospital of Xinjiang Uygur Autonomous RegionUrumqi 830001Xinjiang Uygur Autonomous RegionChina

Celiac disease(CD)is a chronic immune-mediated intestinal disease with genetic *** is characterized by inflammatory damage to the small intestine after ingestion of cereals and products containing gluten *** recent years,the global prevalence rate of CD has been approximately 1%,and is gradually *** patients adhere to a gluten-free diet(GFD)throughout their entire ***,it is difficult to adhere strictly to a *** CD may be accompanied by gastrointestinal symptoms,such as diarrhea,abdominal pain,and extraintestinal symptoms caused by secondary *** studies have suggested that CD is associated with intestinal tumors such as enteropathyassociated T-cell lymphoma(EATL),small bowel cancer(SBC),and colorectal *** this study,we reviewed related studies published in the literature to provide a reference for the prevention and treatment of intestinal tumors in patients with *** with the general population,CD patients had a high total risk of SBC and EATL,but not colorectal *** protective effect of GFD on CD-related malignancies is *** studies are needed to confirm whether GFD treatment can reduce the risk of intestinal neoplasms in CD.

关键词： Celiac disease Gluten-free diet Intestinal neoplasms Small bowel cancer Enteropathy-associated T-cell lymphoma Colorectal cancer

Research into the regional Characteristics of the Tectonic Stress Field in Jiashi, xinjiang and Its Surrounding Areas

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Earthquake Research in china 2007年第4期21卷 397-408页

作者： gao guoying Wang Haitao Nie Xiaohong Long Haiying Earthquake Administration of xinjiang uygur autonomous region Urumqi 830011 China

Jiashi and its surrounding areas are composed of many structural zones. Using the focal mechanism solutions of 59 moderately strong earthquakes in Jiashi and its surrounding areas, and combining these with the calculation results of system cluster and stress field inversion, we aualyzed the evolvement characteristics of the stress field for different times and different regions. The results were as follows： The earthquakes in Jiashi are mainly strike-slip. However, those of the Kalpin block are mainly reverse events, showing an obvious thrusting. The regional characteristics are different from other areas. The direction of the regional principal stress field is near NS. However, under different tectonic backgrounds, the directions of the stress fields are different. The direction of the principal compress stress is near NS in the Kashi-Wuqia area. But before and after the 3 earthquakes with M7.0, dynamic evolution from NW to NS and then to NE with time process was observed. The Kalpin block has been dominated by a consistent stress field in the NW direction for a long time. However, the direction of the stress field of the Jiashi region is NE. Since 1996, the direction of the regional stress field has changed obviously. The direction of the P axis was deflected towards the NE, and the plunge angle increased. The result shows clearly the regional characteristics and variation of the distribution pattern of the stress field in different tectonic environments.

关键词： Focal mechanism solution Tectonic stress field region characteristic Jiashi andits surrounding area