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Separation of tungsten and molybdenum with solvent extraction using functionalized ionic liquid tricaprylmethylammonium bis(2,4,4-trimethylpentyl)phosphinate

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International Journal of Minerals,Metallurgy and Materials 2021年第11期28卷 1769-1776页

作者： Fei Cao Wei Wang De-zhou Wei wen-gang liu School of Resource and Civil Engineering Northeastern UniversityShenyang 110819China Zhengzhou Institute of Multipurpose Utilization of Mineral Resources CAGSZhengzhou 450006China Key Laboratory for Polymetallic Ores’Evaluation and Utilization MNRZhengzhou 450006China

Functionalized ionic liquids(FILs)as extractants were employed for the separation of tungsten and molybdenum from a sulfate solution for the first *** effects of initial pH,extractant concentration,metal concentrations in the feed were comprehensively *** results showed that tricaprylmethylammonium bis(2,4,4-trimethylpentyl)phosphinate([A336][Cyanex272])could selectively extract W over Mo at an initial pH value of 5.5;the best separation factorβ_(W/Mo) of 25.61 was obtained for a solution with low metal concentrations(WO3:2.49 g/L,Mo:1.04 g/L).The[A336][Cyanex272]system performed effectively for solutions of different W/Mo molar ratios and different metal ion concentrations in the *** chemical reaction between[A336][Cyanex272]and W followed the ion association mechanism,which was further proved by the Fourier-transform infrared(FTIR)spectra of loaded[A336][Cyanex272]and the free *** stripping experiments indicated that 95.48%W and 100.00%Mo were stripped using a 0.20 mol/L sodium hydroxide ***,the selective extractions of W and Mo from two synthetic solutions of different high metal concentrations were obtained;the separation factorβW/Mo reached 23.24 and 17.59 for the first and second solutions,*** results suggest the feasibility of[A336][Cyanex272]as an extractant for the separation of tungsten and molybdenum.

关键词： tungsten molybdenum ionic liquid separation solvent extraction

Existence of Solutions for p-Laplace Equations Subjected to Neumann Boundary Value Problem

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Journal of China University of Mining and Technology 2006年第3期16卷 381-384页

作者： HU Zhi-gang RUI wen-juan liu wen-bing School of Sciences China University of Mining ＆ Technology Xuzhou Jiangsu 221008 China

The existence of solutions for one dimensional p-Laplace equation （φp（u′））′=f（t,u,u′） with t∈（0,1） and Фp（s）=｜s｜^p-2 s, s≠0 subjected to Neumann boundary value problem at u′（0） = 0, u′（1） = 0. By using the degree theory, the sufficient conditions of the existence of solutions for p-Laplace equation subjected to Neumann boundary value condition are established.

关键词： p-Laplace equation neumann boundary value problem degree theory

Design and comparison of hybrid multi-bend achromat lattices for HALF storage ring

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Nuclear Science and Techniques 2023年第7期34卷 189-197页

作者： Peng-Hui Yang gang-wen liu Jian-Hao Xu Wei-Wei Li Tian-Long He Zheng-He Bai National Synchrotron Radiation Laboratory University of Science and Technology of ChinaHefei 230029China

The Hefei Advanced Light Facility(HALF)proposed by the National Synchrotron Radiation Laboratory is a green-field vacuum ultraviolet and soft X-ray diffraction-limited storage ring light source with a beam energy of 2.2 GeV and emittance goal of less than 100 pm *** by the ESRF-EBS hybrid multi-bend achromat(HMBA),SLS-2,and Diamond-II lattices,we have proposed and designed a modified H6BA lattice as the baseline lattice of the HALF storage ring with 20 identical cells and a natural emittance of approximately 86 pm *** this paper,three other types of HMBA lattices including two H7BA lattices and a H6BA lattice are designed for HALF with the same number of *** main storage ring proper-ties of these four HMBA lattices are *** the intra-beam scattering(IBS)effect is significant in the HALF storage ring,we calculate and compare the equilibrium emittances of the four lattices with IBS *** comparisons show that the present modified H6BA lattice,which has a relatively low equilibrium emittance and more straight sections,is preferred for the HALF storage ring after a comprehensive consideration.

关键词： Hefei advanced light facility Lattice design Hybrid MBA lattice Intra-beam scattering

Visualization analysis of research hotspots and trends on gastrointestinal tumor organoids

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World Journal of Gastrointestinal Oncology 2024年第6期16卷 2826-2841页

作者： gang Wang Tao liu wen-Ting He School of Basic Medical Sciences Lanzhou UniversityLanzhou 730000Gansu ProvinceChina Digestive System Tumor Prevention and Treatment and Translational Medicine Engineering Innovation Center of Lanzhou University Lanzhou UniversityLanzhou 730000Gansu ProvinceChina Digestive System Tumor Translational Medicine Engineering Research Center of Gansu Province Lanzhou UniversityLanzhou 730000Gansu ProvinceChina The Second Hospital&Clinical Medical School Lanzhou UniversityLanzhou 730030Gansu ProvinceChina

BACKGROUND Gastrointestinal tumor organoids serve as an effective model for simulating cancer in vitro and have been applied in basic biology and preclinical *** over a decade of development and increasing research achievements in this field,a systematic and comprehensive analysis of the research hotspots and future trends is *** To address this problem by employing bibliometric tools to explore the publication years,countries/regions,institutions,journals,authors,keywords,and references in this *** The literature was collected from Web of Science ***-6.2R4,a widely used bibliometric analysis software package,was used for institutional analysis and reference burst *** 1.6.19 was used for journal cocitation analysis,author co-authorship and co-citation ***‘online platform for bibliometric analysis(https://***/app)’was used to assess the total number of publications and the cooperation relationships between ***,we employed the bibliometric R software package(version R.4.3.1)in R-studio,for a comprehensive scientific analysis of the *** Our analysis included a total of 1466 publications,revealing a significant yearly increase in articles on the study of gastrointestinal tumor *** United States(n=393)and Helmholtz Association(n=93)have emerged as the leading countries and institutions,respectively,in this field,with Hans Clevers and Toshiro Sato being the most contributing *** most influential journal in this field is *** most impactful reference is"Long term expansion of epithelial organs from human colon,adenoma,adenocarcinoma,and Barrett's epithelium".Keywords analysis and citation burst analysis indicate that precision medicine,disease modeling,drug development and screening,and regenerative medicine are the most cutting-edge *** focal points were further detailed based on the *** This bibl

关键词： Gastrointestinal tumor organoids Bibliometric analysis Drug development and screening Model CiteSpace

An Approximation Algorithm for the Parallel-Machine Customer Order Scheduling with Delivery Time and Submodular Rejection Penalties

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Journal of the Operations Research Society of China 2024年第2期12卷 495-504页

作者： Hong-Ye Zheng Suo-gang Gao wen liu Bo Hou School of Mathematical Sciences Hebei Normal UniversityShijiazhuang 050024HebeiChina

In this paper,we consider the parallel-machine customer order scheduling with delivery time and submodular rejection *** this problem,we are given m dedicated machines in parallel and n customer *** order has a delivery time and consists of m product types and each product type should be manufactured on a dedicated *** order is either rejected,in which case a rejection penalty has to be paid,or accepted and manufactured on the m dedicated *** objective is to find a solution to minimize the sum of the maximum delivery completion time of the accepted orders and the penalty of the rejected orders which is determined by a submodular *** design an LP rounding algorithm with approximation ratio of n+1 for this problem.

关键词： Order scheduling Delivery time Submodular rejection penalty Approximation algorithm

Total ionizing dose effect modeling method for CMOS digital-integrated circuit

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Nuclear Science and Techniques 2024年第2期35卷 32-46页

作者： Bo Liang Jin-Hui liu Xiao-Peng Zhang gang liu wen-Dan Tan Xin-Dan Zhang School of Computer Science and Technology Xidian UniversityXi’an 710071China

Simulating the total ionizing dose(TID)of an electrical system using transistor-level models can be difficult and expensive,particularly for digital-integrated circuits(ICs).In this study,a method for modeling TID effects in complementary metaloxide semiconductor(CMOS)digital ICs based on the input/output buffer information specification(IBIS)was *** digital IC was first divided into three parts based on its internal structure:the input buffer,output buffer,and functional *** of these three parts was separately *** the IBIS model,the transistor V-I characteristic curves of the buffers were processed,and the physical parameters were extracted and modeled using *** the functional area,logic functions were modeled in VHDL according to the data sheet.A golden digital IC model was developed by combining the input buffer,output buffer,and functional area ***,the golden ratio was reconstructed based on TID experimental data,enabling the assessment of TID effects on the threshold voltage,carrier mobility,and time series of the digital *** experiments were conducted using a CMOS non-inverting multiplexer,NC7SZ157,and the results were compared with the simulation results,which showed that the relative errors were less than 2%at each dose *** confirms the practicality and accuracy of the proposed modeling *** TID effect model for digital ICs developed using this modeling technique includes both the logical function of the IC and changes in electrical properties and functional degradation impacted by TID,which has potential applications in the design of radiation-hardening tolerance in digital ICs.

关键词： CMOS digital-integrated circuit Total ionizing dose IBIS model Behavior-physical hybrid model Physical parameters

Autophagy and its role in gastrointestinal diseases

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World Journal of Gastroenterology 2024年第36期30卷 4014-4020页

作者： Bo-Zong Shao wen-gang Zhang Zhen-Yu liu En-Qiang Linghu Department of Gastroenterology First Medical Center of Chinese People’s Liberation Army General HospitalBeijing 100853China

Gastrointestinal disorders encompass a spectrum of conditions affecting various organs within the digestive system,such as the esophagus,stomach,colon,rectum,pancreas,liver,small intestine,and bile *** role of autophagy in the etiology and progression of gastrointestinal diseases has garnered significant *** paper seeks to evaluate the impact and mechanisms of autophagy in gastrointestinal disorders by synthesizing recent research ***,we delve into inflammation-related gastrointestinal conditions,including ulcerative colitis,Crohn’s disease,and pancreatitis,as well as gastrointestinal cancers such as esophageal,gastric,and colorectal ***,we provide commentary on a recent publication by Chang et al in the World Journal of *** objective is to offer fresh perspectives on the mechanisms and therapeutic approaches for these gastrointestinal *** review aims to offer new perspectives on the mechanisms and therapeutic strategies for gastrointestinal disorders by critically analyzing relevant *** discussed,the role of autophagy in gastrointestinal diseases is complex and,at times,*** harness the full therapeutic potential of autophagy in treating these conditions,more in-depth research is imperative.

关键词： Autophagy Inflammation Cancer Inflammatory bowel disease Pancreatitis

A multi-omics technology to the study of lactic acid bacteria responses to environmental stress: the past， current and future trends

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Food Science and Human Wellness 2024年

作者： Yaqi liu wen Ma gang Jin Wine Research Institute， Ningxia University Engineering Research Center of Grape and Wine， Ministry of Education

Lactic acid bacteria and the fermentation environment interact to form an intertwined system. Lactic acid bacteria are constantly evolving to adapt to different fermentation environments， causing changes in their physiological processes. To achieve a targeted improvement of their adaptability to various environments， a detail analysis of their evolutionary physiological processes is required. While several studies have been carried out in the past by using single-omics techniques to investigate their response to environmental stress， most researchers are now using a multi-omics approach to explore more detail in the biological regulatory networks and molecular mechanisms of lactic acid bacteria in response to environmental stress， thereby overcoming the limitations of single- omics analysis. Scope and approach: In this review， we describe the various single-omics approaches that have been used to study environmental stress in lactic acid bacteria， present the advantages of various multi-omics combined analysis approaches， and discuss the potential and practicality of applying emerging single-cell transcriptomics and single-cell metabolomics techniques to the molecular mechanism study of microbes response to environmental stress. Key ?ndings and conclusions: Multi-omics approaches enable the accurate identification of complex microbial physiological processes in different environments， allow people to comprehensively reveal the molecular mechanisms of microbes response to stress from different perspectives. Single-cell omics techniques， analyze the targeted regulation of microbial functions in a multi-dimensional space， provides a new perspective on understanding microbes responses environment stress.

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In-situ synthesis of quantum dots in the nucleus of live cells

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National Science Review 2024年第3期11卷 172-182页

作者： Yusi Hu Zhi-gang Wang Haohao Fu Chuanzheng Zhou wensheng Cai Xueguang Shao Shu-Lin liu Dai-wen Pang State Key Laboratory of Medicinal Chemical Biology Frontiers Science Centre for New Organic MatterTianjin Key Laboratory of Biosensing and Molecular Recognition Research Centre for Analytical Sciences College of Chemistry School of Medicine and Frontiers Science Centre for Cell Responses Nankai University Haihe Laboratory of Sustainable Chemical Transformations

The cell nucleus is the main site for the storage and replication of genetic material, and the synthesis of substances in the nucleus is rhythmic, regular and strictly regulated by physiological processes. However,whether exogenous substances, such as nanoparticles, can be synthesized in situ in the nucleus of live cells has not been reported. Here, we have achieved in-situ synthesis of CdSxSe1-xquantum dots（QDs） in the nucleus by regulation of the glutathione（GSH） metabolic pathway. High enrichment of GSH in the nucleus can be accomplished by the addition of GSH with the help of the Bcl-2 protein. Then, high-valence Se is reduced to low-valence Se by glutathione-reductase-catalyzed GSH, and interacts with the Cd precursor formed through Cd and thiol-rich proteins, eventually generating QDs in the nucleus. Our work contributes to a new understanding of the syntheses of substances in the cell nucleus and will pave the way for the development of advanced ‘supercells’.

关键词： glutathione live cell nucleus quantum dot intracellular synthesis