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Journal of Wuhan University of Technology(Materials Science) 2024年第1期39卷 160-166页

作者： A Visagan P ganesh Department of Production Technology Madras Institute of TechnologyChennai-600044India

We investigated the parametric optimization on incremental sheet forming of stainless steel using Grey Relational Analysis(GRA) coupled with Principal Component Analysis(PCA). AISI 316L stainless steel sheets were used to develop double wall angle pyramid with aid of tungsten carbide tool. GRA coupled with PCA was used to plan the experiment conditions. Control factors such as Tool Diameter(TD), Step Depth(SD), Bottom Wall Angle(BWA), Feed Rate(FR) and Spindle Speed(SS) on Top Wall Angle(TWA) and Top Wall Angle Surface Roughness(TWASR) have been studied. Wall angle increases with increasing tool diameter due to large contact area between tool and workpiece. As the step depth, feed rate and spindle speed increase,TWASR decreases with increasing tool diameter. As the step depth increasing, the hydrostatic stress is raised causing severe cracks in the deformed surface. Hence it was concluded that the proposed hybrid method was suitable for optimizing the factors and response.

关键词： single point incremental forming AISI 316L taguchi grey relation analysis principal component analysis surface roughness scanning electron microscopy

Performance assessment of prefabricated vertical drains in mitigating soil reliquefaction subjected to repeated seismic events using shaking table experiments

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Frontiers of Structural and Civil Engineering 2024年第3期18卷 411-427页

作者： Gowtham PADMANABHAN ganesh Kumar SHANMUGAM Department of Earthquake Engineering Indian Institute of Technology RoorkeeUttarakhand 247667India Geotechnical Engineering Division CSIR-Central Building Research Institute Academy of Scientific and Innovative Research(AcSIR)Uttarakhand 247667India

The use of prefabricated vertical drains(PVD)in liquefiable deposits is gaining attention due to enhanced ***,investigations on PVD in mitigating re-liquefaction during repeated shaking events are not *** study performed a series of shaking table experiments on untreated and PVD-treated specimens prepared with 40%and 60%relative *** sinusoidal loading was applied with an incremental peak acceleration of 0.1g,0.2g,0.3g,and 0.4g,at 5 Hz shaking frequency with 40 s *** performance of treated ground was evaluated based on the generation and dissipation of excess pore water pressure(EPWP),induced sand densification,subsidence,and cyclic stress *** addition,the strain accumulated in fresh and exhumed PVD was investigated using geotextile tensile testing apparatus aided with digital image *** evidence of pore pressure was reported up to 0.2g peak acceleration for 40%and 60%relative density *** continuous occurrence of soil densification and drainage medium restrained and delayed the generation of EPWP and expedited the dissipation *** study demonstrates PVD can mitigate re-liquefaction,without suffering from deterioration,when subjected to medium to high intense repeated shaking events.

关键词： prefabricated vertical drains drainage re-liquefaction shaking table digital image correlation

Extension of Distribution Transformer Life in the Presence of Smart Inverter-based Distributed Solar Photovoltaic Systems

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CSEE Journal of Power and Energy Systems 2024年第1期10卷 88-95页

作者： Kanhaiya Kumar Saran Satsangi ganesh Balu Kumbhar Department of Electrical and Electronics Engineering Motihari College of EngineeringMotihariBiharIndia Department of Electrical Engineering National Institute of Technology(NIT)PatnaPatnaBiharIndia Department of Electrical Engineering Indian Institute of Technology(IIT)RoorkeeRoorkeeUttarakhandIndia

A transformer is an essential but expensive power delivery equipment for a distribution *** many distribution utilities worldwide,a sizable percentage of transformers are near the end of their designed *** the same time,distribution utilities are adopting smart inverter-based distributed solar photovoltaic(SPV)systems to maximize renewable *** central objective of this paper is to propose a methodology to quantify the effect of smart inverter-based distributed SPV systems on the aging of distribution *** proposed method is first tested on a modified IEEE-123 node distribution *** that,the procedure is applied to a practical distribution system,i.e.,the Indian Institute of Technology(IIT)Roorkee campus,*** transformer aging models,alongside advanced control functionalities of grid-tied smart inverter-based SPV systems,are implemented in *** open-source simulation tool(OpenDSS)is used to model distribution *** analyze effectiveness of various inverter functionalities,time-series simulations are performed using exponential load models,considering daily load curves from multiple seasons,load types,current harmonics,*** show replacing a traditional inverter with a smart inverter-based SPV system can enable local reactive power generation and may extend the life of a distribution *** results demonstrate,simply by incorporating smart inverter-based SPV systems,transformer aging is reduced by 15%to 22%in comparison to SPV systems operating with traditional inverters.

关键词： Distribution transformer loss of life smart inverter functions solar photovoltaic systems thermal models Volt-VAr control

Combatting Antibiotic Resistance:Regulatory Exclusivities for New Antibiotic Development in the United States and Europe

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Infectious Diseases & Immunity 2024年第2期4卷 79-85页

作者： Vivek Reddy Murthannagari Vaishnavi Parimala Thumpati ganesh GNK Department of Pharmaceutics JSS College of PharmacyJSS Academy of Higher Education&ResearchOotyNilgirisTamil Nadu 643001India.

Antimicrobial resistance is a global concern that has led to millions of deaths *** changes occur naturally in pathogens such as viruses,bacteria,parasites,and *** overcome these concerns,there is a need to develop a new generation of *** an effort to encourage innovation,both the United States(US)and the European Union have introduced exclusivity *** US offered 5 years of additional nonpatent exclusivity for Qualified Infectious Disease Products under the Generating Antibiotic Incentives Now *** parallel,the European Commission offers a patent extension of 12 months across Europe(EU)countries or the option to sell the vouchers to other pharmaceutical companies through transferable exclusivity extension *** review focuses on the most important innovative strategies of antibiotic development the drug approvals,their mode of action,spectra of activity,and targeting of microorganisms,in past 5 years were mentioned,and discusses how to overcome the challenges of drug approval under antibiotic exclusivity in the US and EU,which will benefit the companies to develop novel drugs in several nations.

关键词： Drug resistance,microbial Exclusivity FDA EMA New antibiotics WHO

Exploring Deep Learning Methods for Computer Vision Applications across Multiple Sectors:Challenges and Future Trends

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Computer Modeling in Engineering & Sciences 2024年第4期139卷 103-141页

作者： Narayanan ganesh Rajendran Shankar Miroslav Mahdal Janakiraman SenthilMurugan Jasgurpreet Singh Chohan Kanak Kalita School of Computer Science and Engineering Vellore Institute of TechnologyChennai600127India Department of Computer Science and Engineering Koneru Lakshmaiah Education FoundationVaddeswaram522502India Department of Control Systems and Instrumentation Faculty of Mechanical EngineeringVSB-Technical University of OstravaOstrava70800Czech Republic Department of Computer Science and Engineering Vel Tech High Tech Dr.Rangarajan Dr.Sakunthala Engineering CollegeChennai600062India Department of Mechanical Engineering and University Centre for Research&Development Chandigarh UniversityMohali140413India Department of Mechanical Engineering Vel Tech Rangarajan Dr.Sagunthala R&D Institute of Science and TechnologyAvadi600062India

Computer vision(CV)was developed for computers and other systems to act or make recommendations based on visual inputs,such as digital photos,movies,and other *** learning(DL)methods are more successful than other traditional machine learning(ML)methods *** techniques can produce state-of-the-art results for difficult CV problems like picture categorization,object detection,and face *** this review,a structured discussion on the history,methods,and applications of DL methods to CV problems is *** sector-wise presentation of applications in this papermay be particularly useful for researchers in niche fields who have limited or introductory knowledge of DL methods and *** review will provide readers with context and examples of how these techniques can be applied to specific areas.A curated list of popular datasets and a brief description of them are also included for the benefit of readers.

关键词： Neural network machine vision classification object detection deep learning

All-Comers Study of Percutaneous Coronary Interventions with Ultrathin Strut Biodegradable-Polymer Sirolimus-Eluting Stents—ORSHINE Registry

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World Journal of Cardiovascular Diseases 2021年第7期11卷 319-331页

作者： Sridhar Kasturi Shailender Singh S. Vijay Kumar Reddy Kondalrao Gollamandala ganesh mathan Manikandhar Pendyala Chandrashekar Challa Sunshine Heart Institute Secunderabad Telangana Hyderabad India

Current new generation stent technology has made remarkable progress in stent design, structure, and component material to improve its performance in reducing stent thrombosis, and restenosis compared to earlier DES and BMS. Orsiro-Sirolimus eluting stent is new generation ultra-thin strut stent with biodegradable abluminal coating that leaves a polymer free stent after drug release enhances coverage of stent struts and prevents excess neo intimal proliferation. A retrospective data analysis was done to see safety and efficacy of Orsiro in patients treated with ultra-thin DES with Orsiro stents at Sunshine Hospitals, Hyderabad. A total of 331 patients with 525 lesions were treated with 506 Orsiro stents and the major adverse cardiac events (MACE) rate and stent thrombosis (ST) at 2 years’ follow-up were analysed. MACE rate was 1.6% for an average follow-up at 2 years. Out of 2 patients who developed ST, one presented with definite acute stent thrombosis and one with possible, late stent thrombosis and 1.8% non-cardiac death reported during the follow-up. Despite many patients with complex PCI in the ACS subset, Orsiro reduced significant reduction in MACE rate in all spectrum of coronary artery disease patients with excellent acute and long-term results similar to other established FDA-approved current generations stents.

关键词： Ultra-Thin Struts Biodegradable Polymer Sirolimus-Eluting Stent

Accelerated intermetallic phase amorphization in a Mg-based high-entropy alloy powder

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Journal of Magnesium and Alloys 2024年第5期12卷 1792-1798页

作者： Prince Sharma Purvam Mehulkumar Gandhi Kerri-Lee Chintersingh Mirko Schoenitz Edward L.Dreizin Sz-Chian Liou ganesh Balasubramanian Institute for Functional Materials&Devices Lehigh UniversityBethlehemPA 18015USA Center of Materials for Advanced Energetics New Jersey Institute of TechnologyNewarkNJ 07102USA

We describe a novel mechanism for the synthesis of a stable high-entropy alloy powder from an otherwise immiscible Mg-Ti rich metallic mixture by employing high-energy mechanical *** presented methodology expedites the synthesis of amorphous alloy powder by strategically injecting entropic disorder through the inclusion of multi-principal elements in the alloy *** from first principles and materials theory corroborate the results from microscopic characterizations that reveal a transition of the amorphous phase from a precursor intermetallic *** transformation,characterized by the emergence of antisite disorder,lattice expansion,and the presence of nanograin boundaries,signifies a departure from the precursor intermetallic ***,this phase transformation is accelerated by the presence of multiple principal elements that induce severe lattice distortion and a higher configurational *** atomic size mismatch of the dissimilar elements present in the alloy produces a stable amorphous phase that resists reverting to an ordered lattice even on annealing.

关键词： High-entropy alloy High-energy milling Antisite disorder Amorphous Intermetallic

One-Year Clinical Outcomes of Biodegradable Polymer-Coated Sirolimus-Eluting Coronary Stent System in Patients with Coronary Artery Disease

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World Journal of Cardiovascular Diseases 2017年第8期7卷 233-242页

作者： Sridhar Kasturi Shailender Singh Vijay Kumar Shanivaram Kondal Rao Gollamandala ganesh mathan Shiva Kumar Bandimida Manikandhar Pendyala Chandrashekar Challa Sunshine Heart Institute Hyderabad India

Background: The biodegradable polymer-coated sirolimus-eluting coro-nary stent (SES) system for the treatment of coronary artery disease (CAD) has been implanted in a real-world patient population. Aim: The present study was designed to evaluate the safety and performance of MetaforTM sirolimus- eluting coronary stent (SES) system in consecutive patients with CAD in a real-world patient population. Methods: All the consecutive 251 patients who underwent percutaneous coronary interventions with the use of Metafor sirolimus-eluting stents were included in this study. Patients were clinically/tele- phonically followed-up at one-year from August 2015 to August 2016. We observed and analyzed major adverse cardiac event (MACE) defined as the aggregate of cardiac death, myocardial infarction (MI), and any target lesion revascularization (TLR) at one-year. Also, stent thrombosis (ST) was observed at one-year patients follow-up. Results: We collected and analyzed the data for 251 patients. Out of 251 participants, 191 (76.1%) were males, 95 (37.8%) patients had diabetes, 117 (46.6%) had ST-segment-elevation myocardial infarction (STEMI), and 134 (53.4%) had hypertension. Mean patient age was 56.35 ± 11.23 years. A total of 295 lesions were treated, out of which 13.6% of the lesions were the long lesion of ≥40 mm. At one-year, MACE occurred in 4 (1.6%) of 251 patients, consisting of 2 (0.8%) cardiac deaths, 2 (0.8%) MI, and 0 (0%) TLR. Stent thrombosis was reported in one patient (0.4%). Conclusions: This retrospective data demonstrated excellent safety and performance of Metafor SES in a “real-world” consecutive CAD patient, indicating low rates of MACE and ST at one-year follow-up.

关键词： Drug-Eluting Stents Cobalt-Chromium Hybrid Cell Design Percutaneous Coronary Intervention

Safety and Efficacy of a Novel Everolimus-Eluting Stent System in “Real-World” Patients with Coronary Artery Disease: A Report of Preliminary Outcomes

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World Journal of Cardiovascular Diseases 2016年第12期6卷 458-467页

作者： Sridhar Kasturi Srinivas Polasa Shailender Singh Vijay Kumar Reddy Kondal Rao ganesh mathan Shiva Kumar Bandimida Manikandhar Pendyala Chandrashekar Challa Sunshine Heart Institute Secunderabad India Chalmeda Anandrao Institute of Medical Sciences Karimnagar India

Introduction: Tetrilimus (Sahajanand Medical Technologies Pvt. Ltd., Surat, India) is a recently-introduced biodegradable-polymer coated everolimus-eluting cobalt-chromium coronary stent system with an ultra-thin strut thickness. We aimed to evaluate the clinical outcomes with Tetrilimus coronary stents in “real-world” patients with coronary artery disease. Methods: In this retrospective, single-arm, open-label, multi-center registry, all consecutive patients who received Tetrilimus stents between July-2015 and April-2016 at two tertiary-care centers in India were analyzed. Primary endpoint was 30-day incidence of major adverse cardiac events (MACE), defined as a composite of cardiac death, myocardial infarction, target lesion revascularization, and target vessel revascularization. The Academic Research Consortium (ARC)-defined stent thrombosis was assessed as additional safety endpoint. Results: During the study period, 280 Tetrilimus stents (1.4 ± 0.5 stent/patient) were implanted to treat 252 coronary lesions (1.1 ± 0.3 stent/lesion) in 208 patients (age: 57.5 ± 11.9 years). Of study population, 65.9% were males, 46.6% were hypertensives, 25% were diabetics, 36.5% were alcoholics, 29.3% were smokers, 13.9% were tobacco chewers, 5.3% had previous revascularization, and 45.2% displayed multi-vessel disease. Of treated lesions, 67.5% were complex and 18.7% had total occlusion. Average length and diameter of implanted stents were 25.5 ± 8.8 mm and 2.9 ± 0.3 mm respectively. Subsequently, 30-day MACE were reported in 2 (0.96%) patients;both cases owing to in-hospital cardiac deaths. Events of stent thrombosis or noncardiac death were not reported in any patient. Conclusion: Low MACE rates and absence of stent thrombosis at early 30-day follow-up indicates that Tetrilimus everolimus-eluting stents may have encouraging safety and efficacy in unselected “real-world” patients with coronary artery disease.

关键词： Biodegradable Polymer Percutaneous Coronary Intervention Everolimus-Eluting

Significance and Predictive Classification Algorithms in Sentiment Analysis

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Journal of Harbin Institute of Technology(New series) 2024年

作者： V Uma V ganesh Department of Computer and Information Science Annamalai University Department of Computer Science Government Arts College (Autonomous) Kumbakonam

In recent times， an abrupt upswing has emerged within the data mining domain， particularly within the sphere of sentiment analysis. Encompassing diverse dimensions such as sentiment extraction， subjectivity categorization， opinion summarization， and spam detection， sentiment analysis， also acknowledged as Opinion Mining (OM)， undertakes a mathematical exploration into the perspectives， emotions， evaluations， and conduct of individuals toward entities， encompassing products， services， individuals， and events. The advent of web technology tools empowers users to liberally articulate their opinions across varied online platforms， culminating in the generation of a substantial corpus of invaluable yet unstructured data. This exposition scrutinizes the importance of harnessing this data， delving into the intricate process of refining and metamorphosing it for subsequent operations like classification and aspect-oriented sentiment analysis. The crux of the discourse centers on a thorough scrutiny of four data mining algorithms deployed for prognostication and categorization， providing insights into their efficacy within the domain of sentiment analysis. This investigation transcends into pragmatic applications， challenges encountered in the field， and potential trajectories ahead， culminating in a nuanced comprehension of the dynamic panorama of sentiment analysis and its ramifications.

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