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Hazardous effects of fried potato chips on the development of retina in albino rats

Asian Pacific Journal of Tropical Biomedicine 2011年第4期1卷 253-260页

作者： Hassan I El-Sayyad Saber A Sakr gamal m badawy Hanaa S Afify Department of Zoology Faculty of ScienceMansoura UniversityMansouraEgypt Department of Zoology Faculty of ScienceMenoufiya UniversityShebin El-komEgypt

Objective:To evaluate the hazardous effects of fried potato chips upon the retina of two developmental stages of the albino rats aged 7 and 14 days from ***:Pregnant rats were arranged into two groups:control pregnant rats and consequently their delivered newborns until reaching 7 and 14 days old from parturition and fried potato chips group in which pregnant rats at the 6th day of gestation maintained on diet formed of fried potato chips supplied from the market mixed with standard diet at a concentration of 50%per each till 7 and 14 *** fold integrated approaches were adopted,namely,histological,ultrastructural and proteomic ***:Histological examination of the retina of the experimental offsprings revealed many histopathological changes,including massive degeneration,vacuolization and cell loss in the ganglion cell layer,as well as general reduction in retinal *** the ultrastructural level,the retina of experimental offsprings exhibited number of deformities,including ill differentiated and degenerated nuclear layer,malformed and vacuolated pigment epithelium with vesiculated and fragmented rough endoplasmic reticulum,degenerated outer segment of photoreceptors,as well as swollen choriocapillaris and loss of neuronal *** analysis of retina of the two experimental developmental stages showed variations in the expressed proteins as a result of intoxication which illustrated the adverse toxic effects of fried potato chips upon the ***:It can be concluded that the effect of fried potato chips on the development of retina in rats may be due to the presence of acrylamide or its metabolite.

关键词： Fried potato chips Retina Development Histology Ultrastructure Albino rats Hazardous effect Proteomic analysis Acrylamide metabolite

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Ensemble machine Learning to Enhance Q8 Protein Secondary Structure Prediction

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Computers, materials & Continua 2022年第11期73卷 3951-3967页

作者： moheb R.Girgis Rofida m.gamal Enas Elgeldawi Computer Science Department Faculty of ScienceMinia University61519MiniaEgypt

Protein structure prediction is one of the most essential objectives practiced by theoretical chemistry and bioinformatics as it is of a vital importance in medicine,biotechnology and *** secondary structure prediction(PSSP)has a significant role in the prediction of protein tertiary structure,as it bridges the gap between the protein primary sequences and tertiary structure *** secondary structures are classified into two categories:3-state category and 8-state *** the 3 states and the 8 states of secondary structures from protein sequences are called the Q3 prediction and the Q8 prediction problems,*** 8 classes of secondary structures reveal more precise structural information for a variety of applications than the 3 classes of secondary structures,however,Q8 prediction has been found to be very challenging,that is why all previous work done in PSSP have focused on Q3 *** this paper,we develop an ensemble machine Learning(mL)approach for Q8 PSSP to explore the performance of ensemble learning algorithms compared to that of individual mL algorithms in Q8 *** ensemble members considered for constructing the ensemble models are well known classifiers,namely SVm(Support Vector machines),KNN(K-Nearest Neighbor),DT(Decision Tree),RF(Random Forest),and NB(Naïve Bayes),with two feature extraction techniques,namely LDA(Linear Discriminate Analysis)and PCA(Principal Component Analysis).Experiments have been conducted for evaluating the performance of single models and ensemble models,with PCA and LDA,in Q8 *** novelty of this paper lies in the introduction of ensemble learning in Q8 PSSP *** experimental results confirmed that ensemble mL models are more accurate than individual mL *** also indicated that features extracted by LDA are more effective than those extracted by PCA.

关键词： Protein secondary structure prediction(PSSP) Q3 prediction Q8 prediction ensemble machine leaning boosting bagging

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Poultry genetic heritage cryopreservation and reconstruction:advancement and future challenges

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Journal of Animal Science and Biotechnology 2023年第1期14卷 15-32页

作者： Yanyan Sun Yunlei Li Yunhe Zong gamal m.K.mehaisen Jilan Chen Key Laboratory of Animal(Poultry)Genetics Breeding and Reproduction Ministry of Agriculture and Rural AffairsInstitute of Animal ScienceChinese Academy of Agricultural SciencesBeijing 100193China. Department of Animal Production Faculty of AgricultureCairo UniversityGiza 12613Egypt.

Poultry genetics resources,including commercial selected lines,indigenous breeds,and experimental lines,are now being irreversibly lost at an alarming rate due to multiple reasons,which further threats the future livelihood and academic *** of germplasm may reduce the risk of catastrophic loss of genetic diversity by guaranteeing that a pool of genetic variability is available to ensure the reintroduction and replenishment of the genetic *** setting up of biobanks for poultry is challenging because the high sensitiveness of spermatozoa to freezing–thawing process,inability to cryopreserve the egg or embryo,coupled with the females being heterogametic *** progress in cryobiology and biotechnologies have made possible the extension of the range of germplasm for poultry species available in cryobanks,including semen,primordial germ cells,somatic cells and *** this review,we introduce the state-of-the-art technologies for avian genetic resource conservation and breed reconstruction,and discuss the potential challenges for future study and further extending of these technologies to ongoing and future conservation efforts.

关键词： Breed reconstruction Cryopreservation Germplasm Gonad PGC Poultry Semen Somatic cell

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Nanotechnology for Water Treatment: Is It the Best Solution Now?

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Journal of Earth Science 2023年第5期34卷 1616-1620页

作者： moustafa gamal Snousy Hassan mohamed Helmy Jianhua Wu m.F.Zawrah A.Abouelmagd Egyptian Petroleum Sector Petrotrade Co.1 Anwar Al Moftty St.-Abbas El Akkad St.-Nasr CityCairoEgypt Geology Department Faculty of ScienceMinia UniversityEl-Minia 61519Egypt School of Water and Environment Chang'an UniversityNo.126 Yanta RoadXi'an 710054China Key Laboratory of Subsurface Hydrology and Ecological Effects in Arid Region of the ministry of Education Chang'an UniversityNo.126 Yanta RoadXi'an 710054China Key Laboratory of Eco-Hydrology and Water Security in Arid and Semi-Arid Regions of the ministry of Water Resources Chang'an UniversityNo.126 Yanta RoadXi'an 710054China Refractory Ceramics and Building Materials DepartmentCenter of Excellence for Advanced SciencesAdvanced Materials and Nano GroupNational Research CentreCairo 12622-DokkiEgypt Egyptian Petroleum Sector 85 Nasr Road1st DistrictNasr CityCairoEgypt

INTRODUCTION Preservation of the freshwater resources is a big challenge for a healthy civilized *** water consumption increased more than twice the population increase rate,drinking water pollution and freshwater shortage increased dramatically during the last decades(Kar et al.,2012;mueller and Nowack,2010).Only 0.01%of freshwater resources are suitable for human needs(Rashid et al.,2019),even in the areas of abundant freshwater(Yeston et al.,2006).By 2050,over 5 billion of the world population will be under severe fresh water supply conditions due to climate change and urbanization exacerbate(Sealy,2019;Oves et al.,2015;Kar et al.,2012).Currently,one billion people drink unhygienic water,especially in developing countries which leads to severe waterborne diseases which might cause death(Aminiyan et al.,2018).Twelve million people die every year due to this problem(Zhao et al.,2019;Oves et al.,2015).

关键词： abundant freshwater pollution

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Efficient model for Emergency Departments:Real Case Study

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Computers, materials & Continua 2022年第2期70卷 4053-4073页

作者： mohamed Abdel-Basset Abduallah gamal Rehab mohamed mohamed Abouhawwash Abdulwahab Almutairi Osama m.ELkomy Faculty of Computers and Informatics Zagazig UniversityZagazig44519Egypt Department of mathematics Faculty of ScienceMansoura UniversityMansoura35516Egypt Department of Computational mathematics Scienceand Engineering(CMSE)Michigan State UniversityEast LansingMI48824USA School of mathematics Unaizah College of Sciences and ArtsQassim University51452Saudi Arabia

There are several challenges that hospitals are facing according to the emergency department(ED).Themain two issues are department capacity and lead ***,the lack of consensus on performance criteria to evaluateEDincreases the complication of this ***,this study aims to evaluate the efficiency of the emergency department in 20 Egyptian hospitals(12 private and 8 general hospitals)based on 13 performance *** research suggests an integrated evaluation model assess ED under a framework of plithogenic *** proposed framework addressed uncertainty and ambiguity in information with an efficient manner via presenting the evaluation expression by plithogenic *** Envelopment Analysis(DEA)technique is used in order to measure the efficiency of the emergency department of 20 hospitals according to the number of treated patients and effect on patient’s life quality based on 11 *** the Analytic Hierarchy Process(AHP),the weight of efficiency factors will be measured based on neutrosophic linguistic scale pairwise *** operations provide more accurate aggregation result according to contradiction degree between criteria *** results show that ten of the hospitals are providing efficient service in their emergency department,while the other ten are less *** analysis of the results shows that 58%of private hospitals emergency department is operating efficiently,while the efficient general hospitals represent 38%.

关键词： Emergency department plithogenic set data envelopment analysis analytic hierarchy process

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System size dependence in backward relativistic hadron production in pA and AA collisions

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Chinese Physics C 2014年第11期38卷 22-28页

作者： B.m.badawy Reactor Physics Department Nuclear Research Center Atomic Energy Authority Cairo Egypt

Abstract： In this comprehensive study the multiplicity characteristics of the backward emitted relativistic hadron （shower particle） through hadron-nucleus and nucleus-nucleus are overviewed in three dimensions. These dimensions are the projectile size, target size, and energy. To confirm the universality in this production system, wide ranges of system size and energy （Elab～2.1 A up to 200 A GeV） are used. The multiplicity characteristics of this hadron imply a limiting behavior with respect to the projectile size and energy. The target size is the main effective parameter in this production system. The exponential decay shapes is a characteristic feature of the backward shower particle multiplicity distributions. The decay constant changes with the target size to be nearly 2.02, 1.41, and 1.12 for the interactions with CNO, Era, and AgBr nuclei, respectively, irrespective of the projectile size and energy. While the backward production probability and average multiplicity are constants at different projectile sizes and energies, they can be correlated with the target size in power law relations.

关键词： backward relativistic hadron dubna energy and SPS energy multiplicity characteristics system size,nuclear limiting fragmentation

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The Effect of Atrial Septal Defect Closure on Cardiac Volumetric Changes in Adults, Transcatheter Versus Surgical Closure, a Pilot Cardiac magnetic Resonance Study

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Congenital Heart Disease 2023年第6期18卷 679-691页

作者： Amr mansour Noha m.gamal Alaa m.Nady Amr Ibraheem Dalia m.Salah Khaled m.El-maghraby Cardiology Department Congenital and Structural Heart Disease UnitAin Shams University HospitalsFaculty of MedicineAin Shams UniversityCairoEgypt Cardiology Department Faculty of MedicineAssuit UniversityAssuitEgypt Cardiothoracic Surgery Department Faculty of MedicineAssuit UniversityAssuitEgypt Anesthesia Department Faculty of MedicineAssuit UniversityAssuitEgypt

Background:Closure of an atrial septal defect(ASD)reduces right-side heart volumes by abolishing shunting with simultaneous improvement of the left ventricle(LV)ﬁlling and functions due to ventricular interdependence,thereby improving ***,studies conducted on atrial volume changes after ASD closure are *** magnetic resonance(CmR)is considered as the gold standard method for measuring cardiac volume and ***:We aimed to study the effect of transcatheter and surgical closure of secundum ASD on cardiac volumes and systolic functions as well as the fate of tricuspid regurgitation(TR),using CmR ***:We prospectively enrolled 30 adult patients with isolated secundum ASD who were referred to ASD *** evaluation of cardiac chambers indexed volumes,systolic function,myocardial mass index,and tricuspid regurgitant fraction were done at before and 6 months after ***:RV volumes decreased in both groups when compared to baseline(p-value 0.001),the device group had more reduction in volumes and more improvement in RV function after closure(p-value 0.001)when compared to the surgical *** changes in the RV mass index were insigniﬁcant between both groups(p-value 0.31).Functional TR improved to the same extent in both *** ventricular end diastolic volume index(LVEDVI)and LV mass index increased sig-niﬁcantly in both groups when compared to baseline in both groups but with no difference between groups p-value 0.01),left ventricular end systolic volume index(LVESVI)changes were insigniﬁ*** systolic function improved in patients who underwent device closure only(63.53±3.85 vs.67.13±4.34,p-value 0.01).There was a signiﬁcant reduction in right atrial(RA)volumes and an insigniﬁcant decrease in left atrial(LA)volumes,with no difference between ***:Transcatheter and surgical secundum ASD closure resulted in volumetric changes in some cardiac chambers with better improvement in bi-ventricular

关键词： Atrial septal defect closure cardiac volumetric changes functional tricuspid regurgitation cardiac CmR

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Circulating Levels of Hypoxia-regulating microRNAs in Systemic Lupus Erythematosus Patients with Hemolytic Anemia

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Current medical Science 2022年第6期42卷 1231-1239页

作者： Amira m.gamal-Eldeen Cinderella A.Fahmy Bassem m.Raafat Fayez Althobaiti Iman H.Bassyouni Roba m.Talaat Clinical Laboratory Sciences Department College of Applied Medical SciencesTaif UniversityTaif21944Saudi Arabia High Altitude Research Center Prince Sultan Medical ComplexAl-HawiyahTaif UniversityTaif21944Saudi Arabia Cancer Biology and Genetics Laboratory Centre of Excellence for Advanced SciencesNational Research CentreCairo12622Egypt Biochemistry Department National Research CentreCairo12622Egypt Radiological Sciences Department College of Applied Medical SciencesTaif UniversityTaif21944Saudi Arabia Biotechnology Department Faculty of ScienceTaif UniversityTaif21944Saudi Arabia Department of Rheumatology and Rehabilitation Faculty of MedicineCairo UniversityEl-Kasr El-Aini HospitalCairo12613Egypt molecular Biology Department Genetic Engineering and Biotechnology Research Institute(GEBRI)Sadat City UniversitySadat City32897Egypt

Objective microRNAs are fine regulators for gene expression during the post-transcriptional stage in many autoimmune ***(miR-210 and miR-21)play an important role in hypoxia and in inflammation-associated *** lupus erythematosus(SLE)is a chronic systemic autoimmune disease that would potentiate many pathological complications,including hemolytic *** study aimed to investigate the role of hypoxamiRs in SLE/hemolytic anemia *** This work was designed to analyze the circulating levels of↱the miR-210 and miR-21 expressions and hypoxia-inducible factor-1α(HIF-α)in SLE/hemolytic anemia *** activity was evaluated for all patients by SLE Disease Activity Index(SLEDAI).Clinical manifestations/complications and serological/hematological investigations were ***-αconcentration was assayed by ELISA and expression of miR-21 and miR-210 was analyzed by *** The results indicated that the fold change of the miR-210/miR-21 expressions in plasma was significantly elevated in SLE/hemolytic anemia patients.A strong positive correlation between the miR-210 and miR-21 expression levels was also *** the associated-disease complications,hypertension,arthritis,oral ulcers,and serositis were associated with a high circulating miR-210 expression,while the occurrence of renal disorders was associated with the increased miR-21 ***,the HIF-αlevel was remarkably elevated in SLE/hemolytic anemia patients.A high positive correlation was recorded between the HIF-αconcentration and miR-210/miR-21 expression *** occurrence of oral ulcers,arthritis,and hypertension was associated with the increased HIF-α*** the other hand,SLEDAI and white blood cell count were positively correlated with miR-21/*** erythrocyte sedimentation rate was positively correlated with *** The dysregulation of the circulating miR-210/miR-210/HIF-1αlevels in SLE/hemolytic anemia pat

关键词： circulating hypoxamiRs miR-210 and miR-21 hypoxia-inducing factor-1α hemolytic anemia systemic lupus erythematosus

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Handling Big Data in Relational Database management Systems

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Computers, materials & Continua 2022年第9期72卷 5149-5164页

作者： Kamal ElDahshan Eman Selim Ahmed Ismail Ebada mohamed Abouhawwash Yunyoung Nam gamal Behery Faculty of Science Al-Azhar UniversityCairoEgypt Faculty of Computer and Artificial Intelligence Damietta UniversityEgypt Department of mathematics Faculty of ScienceMansoura UniversityMansoura35516Egypt Department of Computational mathematics Scienceand Engineering(CMSE)Michigan State UniversityEast LansingMI48824USA Department of Computer Science and Engineering Soonchunhyang UniversityAsan31538Korea

Currently, relational database management systems (RDBmSs)face different challenges in application development due to the massive growthof unstructured and semi-structured data. This introduced new DBmS categories, known as not only structured query language (NoSQL) DBmSs, whichdo not adhere to the relational model. The migration from relational databasesto NoSQL databases is challenging due to the data complexity. This study aimsto enhance the storage performance of RDBmSs in handling a variety of *** paper presents two approaches. The first approach proposes a convenientrepresentation of unstructured data storage. Several extensive experimentswere implemented to assess the efficiency of this approach that could resultin substantial improvements in the RDBmSs storage. The second approachproposes using the JavaScript Object Notation (JSON) format to representmultivalued attributes and many to many (m:N) relationships in relationaldatabases to create a flexible schema and store semi-structured data. Theresults indicate that the proposed approaches outperform similar approachesand improve data storage performance, which helps preserve software stabilityin huge organizations by improving existing software packages whose replacement may be highly costly.

关键词： Big data RDBmS NoSQL DBmSs mongoDB mySQL unstructured data semi-structured data

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Fractional Optimal Control of Navier-Stokes Equations

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Computers, materials & Continua 2020年第8期64卷 859-870页

作者： Abd-Allah Hyder m.El-badawy King Khalid University College of ScienceDepartment of MathematicsP.O.Box 900461413AbhaSaudi Arabia Department of Engineering mathematics and Physics Faculty of EngineeringAl-Azhar UniversityCairo11371Egypt mathematics Department Al-Azhar UniversityCairoEgypt

In this paper,the non-stationary incompressible fluid flows governed by the Navier-Stokes equations are studied in a bounded *** study focuses on the time-fractional Navier-Stokes equations in the optimal control subject,where the control is distributed within the domain and the time-fractional derivative is proposed as Riemann-Liouville *** addition,the control object is to minimize the quadratic cost *** using the Lax-milgram lemma with the assistance of the fixed-point theorem,we demonstrate the existence and uniqueness of the weak solution to this ***,for a quadratic cost functional subject to the time-fractional Navier-Stokes equations,we prove the existence and uniqueness of optimal ***,via the variational inequality upon introducing the adjoint linearized system,some inequalities and identities are given to guarantee the first-order necessary optimality conditions.A direct consequence of the results obtained here is that when a→1,the obtained results are valid for the classical optimal control of systems governed by the Navier-Stokes equations.

关键词： Optimal control lax-milgram lemma fixed point theorem navier-stokes equations

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