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Assessing the Performance of Some Ranked Set Sampling Designs Using Hybrid Approach

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Computers, materials & Continua 2021年第9期68卷 3737-3753页

作者： mohamed.A.H.Sabry Ehab m.Almetwally Hisham m.Almongy gamal m.ibrahim Faculty of Graduate Studies for Statistical Research Cairo UniversityGiza12613Egypt Faculty of Business Administration Delta University of Science and TechnologyMansoura35511Egypt Department of Statistics Delta University for Science and TechnologyMansouraEgypt High Institute for management Sciences Belqas35511Egypt

In this paper,a joint analysis consisting of goodness-of-fit tests and markov chain monte Carlo simulations are used to assess the performance of some ranked set sampling *** markov chain monte Carlo simulations are conducted when Bayesian methods with Jeffery’s priors of the unknown parameters of Weibull distribution are used,while the goodness of fit analysis is conducted when the likelihood estimators are used and the corresponding empirical distributions are *** ranked set sampling designs considered in this research are the usual ranked set sampling,extreme ranked set sampling,median ranked set sampling,and neoteric ranked set sampling *** intensive monte Carlo simulation study is conducted using Lindley’s approximation algorithm to compute the different designs’-based *** study showed that the dependent design“neoteric ranked set sampling design”is superior to other ranked set designs and the total relative efficiency is higher than the other designs’total relative efficiency.

关键词： Goodness of fit ranked set sampling Weibull distribution Bayesian estimation Lindley’s approximation neoteric ranked set sampling design

Ensemble machine Learning to Enhance Q8 Protein Secondary Structure Prediction

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Computers, materials & Continua 2022年第11期73卷 3951-3967页

作者： moheb R.Girgis Rofida m.gamal Enas Elgeldawi Computer Science Department Faculty of ScienceMinia University61519MiniaEgypt

Protein structure prediction is one of the most essential objectives practiced by theoretical chemistry and bioinformatics as it is of a vital importance in medicine,biotechnology and *** secondary structure prediction(PSSP)has a significant role in the prediction of protein tertiary structure,as it bridges the gap between the protein primary sequences and tertiary structure *** secondary structures are classified into two categories:3-state category and 8-state *** the 3 states and the 8 states of secondary structures from protein sequences are called the Q3 prediction and the Q8 prediction problems,*** 8 classes of secondary structures reveal more precise structural information for a variety of applications than the 3 classes of secondary structures,however,Q8 prediction has been found to be very challenging,that is why all previous work done in PSSP have focused on Q3 *** this paper,we develop an ensemble machine Learning(mL)approach for Q8 PSSP to explore the performance of ensemble learning algorithms compared to that of individual mL algorithms in Q8 *** ensemble members considered for constructing the ensemble models are well known classifiers,namely SVm(Support Vector machines),KNN(K-Nearest Neighbor),DT(Decision Tree),RF(Random Forest),and NB(Naïve Bayes),with two feature extraction techniques,namely LDA(Linear Discriminate Analysis)and PCA(Principal Component Analysis).Experiments have been conducted for evaluating the performance of single models and ensemble models,with PCA and LDA,in Q8 *** novelty of this paper lies in the introduction of ensemble learning in Q8 PSSP *** experimental results confirmed that ensemble mL models are more accurate than individual mL *** also indicated that features extracted by LDA are more effective than those extracted by PCA.

关键词： Protein secondary structure prediction(PSSP) Q3 prediction Q8 prediction ensemble machine leaning boosting bagging

Poultry genetic heritage cryopreservation and reconstruction:advancement and future challenges

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Journal of Animal Science and Biotechnology 2023年第1期14卷 15-32页

作者： Yanyan Sun Yunlei Li Yunhe Zong gamal m.K.mehaisen Jilan Chen Key Laboratory of Animal(Poultry)Genetics Breeding and Reproduction Ministry of Agriculture and Rural AffairsInstitute of Animal ScienceChinese Academy of Agricultural SciencesBeijing 100193China. Department of Animal Production Faculty of AgricultureCairo UniversityGiza 12613Egypt.

Poultry genetics resources,including commercial selected lines,indigenous breeds,and experimental lines,are now being irreversibly lost at an alarming rate due to multiple reasons,which further threats the future livelihood and academic *** of germplasm may reduce the risk of catastrophic loss of genetic diversity by guaranteeing that a pool of genetic variability is available to ensure the reintroduction and replenishment of the genetic *** setting up of biobanks for poultry is challenging because the high sensitiveness of spermatozoa to freezing–thawing process,inability to cryopreserve the egg or embryo,coupled with the females being heterogametic *** progress in cryobiology and biotechnologies have made possible the extension of the range of germplasm for poultry species available in cryobanks,including semen,primordial germ cells,somatic cells and *** this review,we introduce the state-of-the-art technologies for avian genetic resource conservation and breed reconstruction,and discuss the potential challenges for future study and further extending of these technologies to ongoing and future conservation efforts.

关键词： Breed reconstruction Cryopreservation Germplasm Gonad PGC Poultry Semen Somatic cell

Nanotechnology for Water Treatment: Is It the Best Solution Now?

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Journal of Earth Science 2023年第5期34卷 1616-1620页

作者： moustafa gamal Snousy Hassan mohamed Helmy Jianhua Wu m.F.Zawrah A.Abouelmagd Egyptian Petroleum Sector Petrotrade Co.1 Anwar Al Moftty St.-Abbas El Akkad St.-Nasr CityCairoEgypt Geology Department Faculty of ScienceMinia UniversityEl-Minia 61519Egypt School of Water and Environment Chang'an UniversityNo.126 Yanta RoadXi'an 710054China Key Laboratory of Subsurface Hydrology and Ecological Effects in Arid Region of the ministry of Education Chang'an UniversityNo.126 Yanta RoadXi'an 710054China Key Laboratory of Eco-Hydrology and Water Security in Arid and Semi-Arid Regions of the ministry of Water Resources Chang'an UniversityNo.126 Yanta RoadXi'an 710054China Refractory Ceramics and Building Materials DepartmentCenter of Excellence for Advanced SciencesAdvanced Materials and Nano GroupNational Research CentreCairo 12622-DokkiEgypt Egyptian Petroleum Sector 85 Nasr Road1st DistrictNasr CityCairoEgypt

INTRODUCTION Preservation of the freshwater resources is a big challenge for a healthy civilized *** water consumption increased more than twice the population increase rate,drinking water pollution and freshwater shortage increased dramatically during the last decades(Kar et al.,2012;mueller and Nowack,2010).Only 0.01%of freshwater resources are suitable for human needs(Rashid et al.,2019),even in the areas of abundant freshwater(Yeston et al.,2006).By 2050,over 5 billion of the world population will be under severe fresh water supply conditions due to climate change and urbanization exacerbate(Sealy,2019;Oves et al.,2015;Kar et al.,2012).Currently,one billion people drink unhygienic water,especially in developing countries which leads to severe waterborne diseases which might cause death(Aminiyan et al.,2018).Twelve million people die every year due to this problem(Zhao et al.,2019;Oves et al.,2015).

关键词： abundant freshwater pollution

Tagetones A and B, new cytotoxic monocyclic diterpenoids from flowers of Tagetes minuta

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Chinese Journal of Natural medicines 2017年第7期15卷 546-549页

作者： Sabrin Ragab mohamed ibrahim gamal Abd Allah mohamed Department of Pharmacognosy and Pharmaceutical Chemistry College of Pharmacy Taibah University Al-Madinah Al-Munawarah 30078 Saudi Arabia Department of Natural Products and Alternative medicine Faculty of Pharmacy King Abdulaziz University Jeddah 21589 Saudi Arabia

Tagetones A(1) and B(2), two new monocyclic diterpenoids were isolated from the n-hexane fraction of fresh flowers of Tagetes minuta L.(Asteraceae). Their structures were established by multiple spectroscopic methods(IR, HR-ESI-mS, and 1D-, and 2D-NmR), in addition to comparison with literature data. Compound 1 showed cytotoxic activity towards mCF7 and A549 cancer cells with IC_(50) values being 4.68 and 4.24 μmol·L^(-1), respectively, compared to doxorubicin(IC_(50) 0.13 and 1.12 μmol·L^(-1), respectively). Compound 2 also exhibited significant activity against HCT116 cancer cells(IC_(50), 6.30 μmol·L^(-1)).

关键词： Tagetes minuta Asteraceae monocyclic diterpenoids Tagetones Cytotoxic

Efficient model for Emergency Departments:Real Case Study

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Computers, materials & Continua 2022年第2期70卷 4053-4073页

作者： mohamed Abdel-Basset Abduallah gamal Rehab mohamed mohamed Abouhawwash Abdulwahab Almutairi Osama m.ELkomy Faculty of Computers and Informatics Zagazig UniversityZagazig44519Egypt Department of mathematics Faculty of ScienceMansoura UniversityMansoura35516Egypt Department of Computational mathematics Scienceand Engineering(CMSE)Michigan State UniversityEast LansingMI48824USA School of mathematics Unaizah College of Sciences and ArtsQassim University51452Saudi Arabia

There are several challenges that hospitals are facing according to the emergency department(ED).Themain two issues are department capacity and lead ***,the lack of consensus on performance criteria to evaluateEDincreases the complication of this ***,this study aims to evaluate the efficiency of the emergency department in 20 Egyptian hospitals(12 private and 8 general hospitals)based on 13 performance *** research suggests an integrated evaluation model assess ED under a framework of plithogenic *** proposed framework addressed uncertainty and ambiguity in information with an efficient manner via presenting the evaluation expression by plithogenic *** Envelopment Analysis(DEA)technique is used in order to measure the efficiency of the emergency department of 20 hospitals according to the number of treated patients and effect on patient’s life quality based on 11 *** the Analytic Hierarchy Process(AHP),the weight of efficiency factors will be measured based on neutrosophic linguistic scale pairwise *** operations provide more accurate aggregation result according to contradiction degree between criteria *** results show that ten of the hospitals are providing efficient service in their emergency department,while the other ten are less *** analysis of the results shows that 58%of private hospitals emergency department is operating efficiently,while the efficient general hospitals represent 38%.

关键词： Emergency department plithogenic set data envelopment analysis analytic hierarchy process

The Effect of Atrial Septal Defect Closure on Cardiac Volumetric Changes in Adults, Transcatheter Versus Surgical Closure, a Pilot Cardiac magnetic Resonance Study

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Congenital Heart Disease 2023年第6期18卷 679-691页

作者： Amr mansour Noha m.gamal Alaa m.Nady Amr Ibraheem Dalia m.Salah Khaled m.El-maghraby Cardiology Department Congenital and Structural Heart Disease UnitAin Shams University HospitalsFaculty of MedicineAin Shams UniversityCairoEgypt Cardiology Department Faculty of MedicineAssuit UniversityAssuitEgypt Cardiothoracic Surgery Department Faculty of MedicineAssuit UniversityAssuitEgypt Anesthesia Department Faculty of MedicineAssuit UniversityAssuitEgypt

Background:Closure of an atrial septal defect(ASD)reduces right-side heart volumes by abolishing shunting with simultaneous improvement of the left ventricle(LV)ﬁlling and functions due to ventricular interdependence,thereby improving ***,studies conducted on atrial volume changes after ASD closure are *** magnetic resonance(CmR)is considered as the gold standard method for measuring cardiac volume and ***:We aimed to study the effect of transcatheter and surgical closure of secundum ASD on cardiac volumes and systolic functions as well as the fate of tricuspid regurgitation(TR),using CmR ***:We prospectively enrolled 30 adult patients with isolated secundum ASD who were referred to ASD *** evaluation of cardiac chambers indexed volumes,systolic function,myocardial mass index,and tricuspid regurgitant fraction were done at before and 6 months after ***:RV volumes decreased in both groups when compared to baseline(p-value 0.001),the device group had more reduction in volumes and more improvement in RV function after closure(p-value 0.001)when compared to the surgical *** changes in the RV mass index were insigniﬁcant between both groups(p-value 0.31).Functional TR improved to the same extent in both *** ventricular end diastolic volume index(LVEDVI)and LV mass index increased sig-niﬁcantly in both groups when compared to baseline in both groups but with no difference between groups p-value 0.01),left ventricular end systolic volume index(LVESVI)changes were insigniﬁ*** systolic function improved in patients who underwent device closure only(63.53±3.85 vs.67.13±4.34,p-value 0.01).There was a signiﬁcant reduction in right atrial(RA)volumes and an insigniﬁcant decrease in left atrial(LA)volumes,with no difference between ***:Transcatheter and surgical secundum ASD closure resulted in volumetric changes in some cardiac chambers with better improvement in bi-ventricular

关键词： Atrial septal defect closure cardiac volumetric changes functional tricuspid regurgitation cardiac CmR

Circulating Levels of Hypoxia-regulating microRNAs in Systemic Lupus Erythematosus Patients with Hemolytic Anemia

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Current medical Science 2022年第6期42卷 1231-1239页

作者： Amira m.gamal-Eldeen Cinderella A.Fahmy Bassem m.Raafat Fayez Althobaiti Iman H.Bassyouni Roba m.Talaat Clinical Laboratory Sciences Department College of Applied Medical SciencesTaif UniversityTaif21944Saudi Arabia High Altitude Research Center Prince Sultan Medical ComplexAl-HawiyahTaif UniversityTaif21944Saudi Arabia Cancer Biology and Genetics Laboratory Centre of Excellence for Advanced SciencesNational Research CentreCairo12622Egypt Biochemistry Department National Research CentreCairo12622Egypt Radiological Sciences Department College of Applied Medical SciencesTaif UniversityTaif21944Saudi Arabia Biotechnology Department Faculty of ScienceTaif UniversityTaif21944Saudi Arabia Department of Rheumatology and Rehabilitation Faculty of MedicineCairo UniversityEl-Kasr El-Aini HospitalCairo12613Egypt molecular Biology Department Genetic Engineering and Biotechnology Research Institute(GEBRI)Sadat City UniversitySadat City32897Egypt

Objective microRNAs are fine regulators for gene expression during the post-transcriptional stage in many autoimmune ***(miR-210 and miR-21)play an important role in hypoxia and in inflammation-associated *** lupus erythematosus(SLE)is a chronic systemic autoimmune disease that would potentiate many pathological complications,including hemolytic *** study aimed to investigate the role of hypoxamiRs in SLE/hemolytic anemia *** This work was designed to analyze the circulating levels of↱the miR-210 and miR-21 expressions and hypoxia-inducible factor-1α(HIF-α)in SLE/hemolytic anemia *** activity was evaluated for all patients by SLE Disease Activity Index(SLEDAI).Clinical manifestations/complications and serological/hematological investigations were ***-αconcentration was assayed by ELISA and expression of miR-21 and miR-210 was analyzed by *** The results indicated that the fold change of the miR-210/miR-21 expressions in plasma was significantly elevated in SLE/hemolytic anemia patients.A strong positive correlation between the miR-210 and miR-21 expression levels was also *** the associated-disease complications,hypertension,arthritis,oral ulcers,and serositis were associated with a high circulating miR-210 expression,while the occurrence of renal disorders was associated with the increased miR-21 ***,the HIF-αlevel was remarkably elevated in SLE/hemolytic anemia patients.A high positive correlation was recorded between the HIF-αconcentration and miR-210/miR-21 expression *** occurrence of oral ulcers,arthritis,and hypertension was associated with the increased HIF-α*** the other hand,SLEDAI and white blood cell count were positively correlated with miR-21/*** erythrocyte sedimentation rate was positively correlated with *** The dysregulation of the circulating miR-210/miR-210/HIF-1αlevels in SLE/hemolytic anemia pat

关键词： circulating hypoxamiRs miR-210 and miR-21 hypoxia-inducing factor-1α hemolytic anemia systemic lupus erythematosus

Handling Big Data in Relational Database management Systems

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Computers, materials & Continua 2022年第9期72卷 5149-5164页

作者： Kamal ElDahshan Eman Selim Ahmed Ismail Ebada mohamed Abouhawwash Yunyoung Nam gamal Behery Faculty of Science Al-Azhar UniversityCairoEgypt Faculty of Computer and Artificial Intelligence Damietta UniversityEgypt Department of mathematics Faculty of ScienceMansoura UniversityMansoura35516Egypt Department of Computational mathematics Scienceand Engineering(CMSE)Michigan State UniversityEast LansingMI48824USA Department of Computer Science and Engineering Soonchunhyang UniversityAsan31538Korea

Currently, relational database management systems (RDBmSs)face different challenges in application development due to the massive growthof unstructured and semi-structured data. This introduced new DBmS categories, known as not only structured query language (NoSQL) DBmSs, whichdo not adhere to the relational model. The migration from relational databasesto NoSQL databases is challenging due to the data complexity. This study aimsto enhance the storage performance of RDBmSs in handling a variety of *** paper presents two approaches. The first approach proposes a convenientrepresentation of unstructured data storage. Several extensive experimentswere implemented to assess the efficiency of this approach that could resultin substantial improvements in the RDBmSs storage. The second approachproposes using the JavaScript Object Notation (JSON) format to representmultivalued attributes and many to many (m:N) relationships in relationaldatabases to create a flexible schema and store semi-structured data. Theresults indicate that the proposed approaches outperform similar approachesand improve data storage performance, which helps preserve software stabilityin huge organizations by improving existing software packages whose replacement may be highly costly.

关键词： Big data RDBmS NoSQL DBmSs mongoDB mySQL unstructured data semi-structured data