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Individual alcohol consumption by the population of Russia versus regional living conditions

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Global Health Journal 2024年第1期8卷 24-31页

作者： Sergey A.Maksimov Svetlana A.Shalnova galina A.Muromtseva Yuliya A.Balanova Svetlana E.Evstifeeva Anna v.Kapustina Oksana M.Drapkina National Medical Research Center for Therapy and Preventive Medicine Moscow 101990Russia

Background:There are substantial regional differences in drinking alcohol in Russia,both at the population and individual ***,the causes of these differences have not been studied ***:The goal of our study was to examine the effect of regional living conditions on individual alcohol consumption by the population of ***:For the analysis,we used data from a cross-sectional epidemiological study conducted in *** final analytical sample included 18,130 people aged 25-64 *** conducted the interviews face to face,based on which any drinking in the last year,as well as alcohol abuse,were considered as a *** abuse was recorded when the respondent consumed 5.75 or more grams of pure ethanol per day(75th percentile of average daily alcohol consumption among alcohol drinkers).The assessment of the regional living conditions was accomplished via integral indexing,which was previously performed based on publicly available data for *** were assessed using generalized scoring equations with unchanging standard *** associations were expressed by odds ratios(OR)and 95%confidence intervals(C).Results:Deterioration of social conditions and increase in demographic depression in the region of residence increased the odds of any drinking(OR 1.51,95%CI:1.33 to 1.72,Pvely).The odds of alcohol abuse increased with the deterioration of social living conditions and the growth of the industrial development in the region:OR 1.35,95%CI:1.14 to 1.59,Pving conditions on individual drinking alcohol in the population of Russia.

关键词： Alcohol Living environment Regional features Russia

Olefin Polymerization Behavior of Titanium(Iv) Complexes with Fluorinated and Non-fluorinated Aliphatic Phenoxyimine Ligands

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Chinese Journal of Polymer Science 2024年第1期42卷 52-62,I0007页

作者： vladislav A.Tuskaev Kasim F.Magomedov Svetlana Ch.Gagieva Dmitry A.Kurmaev Yulia v.Nelyubina Evgenii K.Golubev Maria D.Evseeva viktor G.vasil'ev galina G.Nikiforova Mikhail I.Buzin vyacheslav S.Bogdanov Boris M.Bulychev Department of Chemistry M.V.Lomonosov Moscow State UniversityMoscow 119992Russian Federation A.N.Nesmeyanov Institute of Organoelement Compounds Russian Academy of SciencesMoscow119991Russian Federation Enikolopov Institute of Synthetic Polymer Materials Russian Academy of SciencesMoscow 117393Russian Federation

A series of Ti(Ⅳ) dichloride and dialkoxide com plexes with phenoxyimine ligands containing fluorinated and nonfluorinated aliphatic imine fragments have been *** molecular structures of complexes 1 and 4 were established by single-crystal X-ray diffraction *** complexes adopt a distorted octahedral coordination structure around the titanium atom and two oxygen atoms are situated in trans position while two nitrogen atoms and two outgoing ligands(Cl or iPrO) are situated in cis *** of activators(MMAO-12 and combinations Et_nAICl_(3-n)+Bu_(2)Mg) and outgoing ligand(Cl or iPrO) nature on the catalytic activity and properties of the resulting polymers was *** Ti complexes,despite the nature of the outgoing ligands(Cl or iPrO) in the presence of Al/Mg activators,was found to display a high ethylene polymerization activity in the range 1600-3830 kg_(polymer)·mol_(Ti)^(-1)·h^(-1)·atm^(-1) with a viscosity average molecular weight(M_v) value in the range 1.1×10~6-7.1×10~6 Dalton(Da).The resulting UHMWPE can be processed by a solventless method into high-strength and high-modulus oriented *** rheological characteristics of a polymer melt have been *** absence of a cross-over point did not allow to compare the values of the molecular weight distribution of polymers obtained on fluorinated and non-fluorinated pre-catalysts,however,the estimation of the entanglement density is in good agreement with the mechanical characteristics of oriented film *** activation with methylalumoxane,the activity of the com plexes decreased very significantly;however,a polymer with a molecular weight of about 12 million Da was *** the process of ethylene/octene-1 copolymerization,fluorine-containing precatalysts showed a clear advantage over non-fluorinated analogues both in activity and in comonomer content.

关键词： FI catalysts Titanium(Iv) (Co)polymerization Al/Mg co-catalyst Ultra-high molecular weight polyethylene

Comprehensive semen examination in patients with pancreatic-sufficient and pancreatic-insufficient cystic fibrosis

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Asian Journal of Andrology 2023年第5期25卷 591-597页

作者： Anna O Sedova Maria I Shtaut Elizaveta E Bragina Tatyana M Sorokina galina v.shmarina Marina v Andreeva Lyubov E Kurilo Stanislav A Krasovskiy Aleksander v Polyakov vyacheslav B Chernykh Research Centre for Medical Genetics Moskvorechie Street 1 Moscow 115522

We examined a cohort of 93 cystic fibrosis(CF)male patients who were pancreatic-sufficient(PS-CF;n=40)or pancreatic-insufficient(PI-CF;n=53).Complex semen examination was performed,including standard semen analysis,quantitative karyological analysis(QKA)of immature germ cells(IGCs),transmission electronic microscopy(TEM),biochemical analysis,and sperm DNA fragmentation by terminal deoxynucleotidyl transferase-mediated dUTP nickend labeling(TUNEL)*** was diagnosed in 83(89.2%)*** other 10(10.8%)patients were found to be nonazoospermic and showed various spermatological diagnoses(asthenozoospermia,n=2;asthenoteratozoospermia,n=3;oligoasthenozoospermia,n=1;oligoasthenoteratozoospermia,n=3;and normozoospermia,n=1)with no specific morphological *** was detected in 89.2%azoospermic and 30.0%nonazoospermic *** seminal pH(vealed in 2.4%azoospermic and 40.0%nonazoospermic semen *** signs of partial meiotic arrest at prophase I were found in 4 of 6 nonazoospermic patients examined by QKA of *** content of fructose and citrate was low in oligospermic and normal in nonoligospermic semen *** increased percentage(>30%)of spermatozoa with noncondensed(“immature”)chromatin was revealed in 2 of 6 nonazoospermic semen samples analyzed by TEM.

关键词： congenital bilateral agenesia/aplasia of vas deferens cystic fibrosis cystic fibrosis transmembrane conductance regulator gene semen spermatozoa

Effects of subsampling on characteristics of RNA-seq data from triple-negative breast cancer patients

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Chinese Journal of Cancer 2015年第10期34卷 427-438页

作者： Alexey Stupnikov galina v Glazko Frank Emmert-Streib Computational Biology and Machine Learning Laboratory Faculty of MedicineHealth and Life SciencesSchool of MedicineDentistry and Biomedical SciencesCenter for Cancer Research and Cell BiologyQueen's University Belfast Division of Biomedical Informatics University of Arkansas for Medical Sciences Computational Medicine and Statistical Learning Laboratory Department of Signal ProcessingTampere University of Technology

Background:Data from RNA-seq experiments provide a wealth of information about the transcriptome of an ***,the analysis of such data is very *** this study,we aimed to establish robust analysis procedures that can be used in clinical ***:We studied RNA-seq data from triple-negative breast cancer ***,we investigated the subsampling of RNA-seq ***:The main results of our investigations are as follows:(1) the subsampling of RNA-seq data gave biologically realistic simulations of sequencing experiments with smaller sequencing depth but not direct scaling of count matrices;(2) the saturation of results required an average sequencing depth larger than 32 million reads and an individual sequencing depth larger than 46 million reads;and(3) for an abrogated feature selection,higher moments of the distribution of all expressed genes had a higher sensitivity for signal detection than the corresponding mean ***:Our results reveal important characteristics of RNA-seq data that must be understood before one can apply such an approach to translational medicine.

关键词： RNA-seq data, Computational genomics, Statistical robustness, High-dimensional biology,Triple-negative breast cancer

On Convergence of MRQI and IMRQI Methods for Hermitian Eigenvalue Problems

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Communications on Applied Mathematics and Computation 2021年第1期3卷 189-197页

作者： Fang Chen Cun-Qiang Miao galina v.Muratova School of Applied Science Beijing Information Science and Technology UniversityBeijing 100192China School of Mathematics and Statistics Central South UniversityChangsha 410083China Laboratory of Computational Mechanics I.I.Vorovich Institute of MathematicsMechanics and Computer ScienceSouthern Federal UniversityRostov-on-Don 344090Russia

Bai et *** the multistep Rayleigh quotient iteration(MRQI)as well as its inexact variant(IMRQI)in a recent work(***.77:2396–2406,2019).These methods can be used to effectively compute an eigenpair of a Hermitian *** convergence theorems of these methods were established under two conditions imposed on the initial guesses for the target eigenvalue and *** this paper,we show that these two conditions can be merged into a relaxed one,so the convergence conditions in these theorems can be weakened,and the resulting convergence theorems are applicable to a broad class of *** addition,we give detailed discussions about the new convergence condition and the corresponding estimates of the convergence errors,leading to rigorous convergence theories for both the MRQI and the IMRQI.

关键词： Hermitian eigenvalue problem MRQI IMRQI Convergence

The boys are back in town: Rethinking the function of ribosomal DNA repeats in the genomic era

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Molecular Plant 2023年第3期16卷 514-516页

作者： Francesca B.Lopez Peter C.McKeown Antoine Fort galina Brychkova Charles Spillane Genetics and Biotechnology Laboratory Plant&AgriBiosciences Research Centre(PABC)Ryan InstituteUniversity of GalwayH91 REW4 GalwayIreland Present address:Department of Plant Biology and Genome Center University of CaliforniaDavisUC Davis Genome CenterDavisCA 95616USA

Next-generation sequencing technological advances,affording high-throughput,scalable,and fast assemblies,have enabled genome editing techniques that allow us to remove,insert,and modify genes for rapid and precise fun... 详细信息

关键词： remove precise function

Stromatolites are the Potential Collectors of Oil and Gas

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地学前缘 2009年第S1期16卷 151-152页

作者： galina Samotorova E.v.Kozlova Geology Department Moscow State University

Stromatolite buildups are spread throughout the Earth and are known in sediments of different age. First stromatolite buildups were investigated in Shark-Bay in Western *** age is valued as 3.5 billion years,the same ... 详细信息

关键词： stromatolites buildups collector oil and gas

Amur tiger conservation education program:A pilot study on program effectiveness

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Integrative Zoology 2015年第4期10卷 403-407页

作者： Anna S.MUKHACHEvA vasilissa v.DERUGINA galina D.MAKSIMOvA Svetlana v.SOUTYRINA Sikhote-Alin Biosphere Zapovednik Primorskii KraiTerneiRussia Wildlife Conservation Society BronxNew YorkUSA Youth Creative Arts Center of Ternei Uragus Ecological ClubTerneiPrimorskii KraiRussia

Anthropogenic impacts are the primary threats to Amur tigers(Panthera tigris altaica)and their *** living in proximity to tigers tend to view them negatively and,often,as a source of revenue on black *** aim to reduce human–tiger conflict by working with young students of Ternei County in the heart of tiger habitat in Primorskii Krai(Province).To inform and influence Ternei County’s future decision-makers,we developed“Safe Conduct”,a year-long education program held in 6 villages,culminating in a multi-school *** tested the efficacy of Safe Conduct as a potential model for tiger conservation educational *** measured levels of student knowledge about tiger ecology,their attitude towards tigers,and their willingness to engage in tiger conservation activites prior to,immediately after and 6 months following the completion of our *** supported the fundamental premise of Safe Conduct that knowledge and attitude towards tigers are *** of tiger ecology and attitude towards tigers increased by the project’s completion;both remained high after 6 ***,commitment to participation in conservation efforts rose temporarily post-program and then *** varied by *** recommend that the reasons for the high performance measures of students in 2 villages be investigated,and that lessons learned be applied to villages that *** Conduct represents a potential model for environmental education programs in Ternei County and elsewhere to educate future generations,to eventually develop a strong commitment to Amur tiger conservation at the community level.

关键词： Amur tiger behavior change conservation children education programs

Mesoscopic Models of Plants Composed of Metallic Nanowires

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Journal of Bionic Engineering 2013年第3期10卷 368-376页

作者： galina K. Strukova Gennady v. Strukov Evgeniya Yu. Postnova Alexander Yu. Rusanov Ivan S. veshchunov Institute of Solid State Physics Russian Academy of Sciences 142432 Chernogolovka Russia

various metallic structures of complex shape resembling living plant organisms （biomimetics） are produced as a result of self-assembly of nanowires growing on porous membranes in the course of pulse current electrodeposition. These structures occur if the electroplating is continued after the nanowires appear on the membrane surface. By varying the membrane ge- ometry, pulse current electroplating parameters, and alternating electrodeposition from two baths composed of a variety of electrolytes, diverse models were fabricated, including a hollow container with a wall thickness of 10 nm 20 nm. This biomimetic method suggests an analogy between the shape-forming processes of plants and their metallic models. Nanostruc- tured mesostructures of various metals （Ag, Pd, Ni）, alloys （PdNi, Pbln） and hybrid structures .（PdNi/Pb, PdNi/Pbln） were obtained. They can be of interest for fundamental research （self-assembly, morphogenesis） as well as for applications in nanotechnology （catalysis, nanoplasmonics, medicine, superhydrophobic surfaces）.

关键词： templated growth pulse electroplating self-assembly metallic mesostructures nanowires fractal branching biomimetic method