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Residual and compensatory changes of resting-state EEG in successful recovery after moderate TBI

Brain Science Advances 2020年第4期6卷 364-378页

作者： galina v.portnova Irina N.Girzhova Olga v.Martynova Institute of Higher Nervous Activity and Neurophysiology of the Russian Academy of Science Moscow 117485Russia The Pushkin State Russian Language Institute Moscow 117485Russia Lomonosov Moscow State University Moscow 119192Russia Centre for Cognition and Decision Making Institute for Cognitive NeuroscienceNational Research University Higher School of EconomicsMoscow 109028Russia

Purpose:Even in years after recovery from moderate traumatic brain injury(moderate TBI),patients complain about residual cognitive impairment and *** hypothesized that non-linear and linear resting-state electroencephalography(rs EEG)features might also reflect neural underpinnings of these ***:We analyzed a 10-minute rs EEG in 77 moderate TBI-survivors and 151 healthy volunteers after cognitive and psychological *** rs EEG analysis included linear measures,such as power spectral density and peak alpha frequency,and non-linear parameters such as Higuchi fractal dimension,envelope frequency,and Hjorth ***:The patients with moderate TBI had higher scores for fatigue and sleepiness and lower scores for mood and life satisfaction than *** behavioral test for directed attention showed a smaller and non-significant between-group *** rs EEG patterns,moderate TBI-group had significantly higher deltaand theta-rhythm power,which correlated with higher sleepiness and fatigue *** higher beta and lower alpha power were associated with a higher attention level in moderate TBI ***-linear rs EEG features were significantly higher in moderate TBI patients than in healthy controls but correlated with sleepiness and fatigue scores in both controls and ***:The rs EEG patterns may reflect compensatory processes supporting directed attention and residual effect of moderate TBI causing subjective fatigue in patients even after full physiological recovery.

关键词： moderate TBI attention fatigue resting state electroencephalography power spectral density Higuchi fractal dimension Hjorth complexity envelope frequency

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Thermogravimetric,kinetic study and gas emissions analysis of the thermal decomposition of waste-derived fuels

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Journal of Environmental Sciences 2024年第3期137卷 155-171页

作者： vadim v.Dorokhov galina S.Nyashina Pavel A.Strizhak Heat and Mass Transfer Laboratory National Research Tomsk Polytechnic University30 Lenin AvenueTomsk 634050Russia

A wide range of wastes can potentially be used to generate thermal and electrical *** co-combustion of several types of waste as part of water-containing waste-derived fuels is a promising method for their *** this research,we use thermogravimetric analysis and differential scanning calorimetry to study the thermal behavior and kinetics of coal slime,biomass,waste oils,and blends on their *** also analyze the concentrations of gaseous *** results show that biomass,oils,and coal slime significantly affect each other in the course of their co-combustion when added to slurry *** preparation of coal-water slurry based on slime and water reduced the ignition and burnout temperature by up to 16%.Adding biomass and waste oils additionally stimulated the slurry ignition and burnout,which occurred at lower *** to dry coal slime,threshold ignition temperatures and burnout temperatures decreased by 6%–9%and 17%–25%,***,the use of biomass and waste oils as part of slurries inhibited NOхand SO_(2)emission by 2.75 *** to the kinetic analysis,added biomass and waste turbine oil provide a 28%–51%reduction in the activation energy as compared to a coal-water slurry without additives.

关键词： Coal-water slurry Water-containing composite fuels Combustion Emission Kinetic TGA-DSC

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Individual alcohol consumption by the population of Russia versus regional living conditions

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Global Health Journal 2024年第1期8卷 24-31页

作者： Sergey A.Maksimov Svetlana A.Shalnova galina A.Muromtseva Yuliya A.Balanova Svetlana E.Evstifeeva Anna v.Kapustina Oksana M.Drapkina National Medical Research Center for Therapy and Preventive Medicine Moscow 101990Russia

Background:There are substantial regional differences in drinking alcohol in Russia,both at the population and individual ***,the causes of these differences have not been studied ***:The goal of our study was to examine the effect of regional living conditions on individual alcohol consumption by the population of ***:For the analysis,we used data from a cross-sectional epidemiological study conducted in *** final analytical sample included 18,130 people aged 25-64 *** conducted the interviews face to face,based on which any drinking in the last year,as well as alcohol abuse,were considered as a *** abuse was recorded when the respondent consumed 5.75 or more grams of pure ethanol per day(75th percentile of average daily alcohol consumption among alcohol drinkers).The assessment of the regional living conditions was accomplished via integral indexing,which was previously performed based on publicly available data for *** were assessed using generalized scoring equations with unchanging standard *** associations were expressed by odds ratios(OR)and 95%confidence intervals(C).Results:Deterioration of social conditions and increase in demographic depression in the region of residence increased the odds of any drinking(OR 1.51,95%CI:1.33 to 1.72,Pvely).The odds of alcohol abuse increased with the deterioration of social living conditions and the growth of the industrial development in the region:OR 1.35,95%CI:1.14 to 1.59,Pving conditions on individual drinking alcohol in the population of Russia.

关键词： Alcohol Living environment Regional features Russia

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Olefin Polymerization Behavior of Titanium(Iv) Complexes with Fluorinated and Non-fluorinated Aliphatic Phenoxyimine Ligands

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Chinese Journal of Polymer Science 2024年第1期42卷 52-62,I0007页

作者： vladislav A.Tuskaev Kasim F.Magomedov Svetlana Ch.Gagieva Dmitry A.Kurmaev Yulia v.Nelyubina Evgenii K.Golubev Maria D.Evseeva viktor G.vasil'ev galina G.Nikiforova Mikhail I.Buzin vyacheslav S.Bogdanov Boris M.Bulychev Department of Chemistry M.V.Lomonosov Moscow State UniversityMoscow 119992Russian Federation A.N.Nesmeyanov Institute of Organoelement Compounds Russian Academy of SciencesMoscow119991Russian Federation Enikolopov Institute of Synthetic Polymer Materials Russian Academy of SciencesMoscow 117393Russian Federation

A series of Ti(Ⅳ) dichloride and dialkoxide com plexes with phenoxyimine ligands containing fluorinated and nonfluorinated aliphatic imine fragments have been *** molecular structures of complexes 1 and 4 were established by single-crystal X-ray diffraction *** complexes adopt a distorted octahedral coordination structure around the titanium atom and two oxygen atoms are situated in trans position while two nitrogen atoms and two outgoing ligands(Cl or iPrO) are situated in cis *** of activators(MMAO-12 and combinations Et_nAICl_(3-n)+Bu_(2)Mg) and outgoing ligand(Cl or iPrO) nature on the catalytic activity and properties of the resulting polymers was *** Ti complexes,despite the nature of the outgoing ligands(Cl or iPrO) in the presence of Al/Mg activators,was found to display a high ethylene polymerization activity in the range 1600-3830 kg_(polymer)·mol_(Ti)^(-1)·h^(-1)·atm^(-1) with a viscosity average molecular weight(M_v) value in the range 1.1×10~6-7.1×10~6 Dalton(Da).The resulting UHMWPE can be processed by a solventless method into high-strength and high-modulus oriented *** rheological characteristics of a polymer melt have been *** absence of a cross-over point did not allow to compare the values of the molecular weight distribution of polymers obtained on fluorinated and non-fluorinated pre-catalysts,however,the estimation of the entanglement density is in good agreement with the mechanical characteristics of oriented film *** activation with methylalumoxane,the activity of the com plexes decreased very significantly;however,a polymer with a molecular weight of about 12 million Da was *** the process of ethylene/octene-1 copolymerization,fluorine-containing precatalysts showed a clear advantage over non-fluorinated analogues both in activity and in comonomer content.

关键词： FI catalysts Titanium(Iv) (Co)polymerization Al/Mg co-catalyst Ultra-high molecular weight polyethylene

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Comprehensive semen examination in patients with pancreatic-sufficient and pancreatic-insufficient cystic fibrosis

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Asian Journal of Andrology 2023年第5期25卷 591-597页

作者： Anna O Sedova Maria I Shtaut Elizaveta E Bragina Tatyana M Sorokina galina v Shmarina Marina v Andreeva Lyubov E Kurilo Stanislav A Krasovskiy Aleksander v Polyakov vyacheslav B Chernykh Research Centre for Medical Genetics Russia Moscow 115522

We examined a cohort of 93 cystic fibrosis(CF)male patients who were pancreatic-sufficient(PS-CF;n=40)or pancreatic-insufficient(PI-CF;n=53).Complex semen examination was performed,including standard semen analysis,quantitative karyological analysis(QKA)of immature germ cells(IGCs),transmission electronic microscopy(TEM),biochemical analysis,and sperm DNA fragmentation by terminal deoxynucleotidyl transferase-mediated dUTP nickend labeling(TUNEL)*** was diagnosed in 83(89.2%)*** other 10(10.8%)patients were found to be nonazoospermic and showed various spermatological diagnoses(asthenozoospermia,n=2;asthenoteratozoospermia,n=3;oligoasthenozoospermia,n=1;oligoasthenoteratozoospermia,n=3;and normozoospermia,n=1)with no specific morphological *** was detected in 89.2%azoospermic and 30.0%nonazoospermic *** seminal pH(vealed in 2.4%azoospermic and 40.0%nonazoospermic semen *** signs of partial meiotic arrest at prophase I were found in 4 of 6 nonazoospermic patients examined by QKA of *** content of fructose and citrate was low in oligospermic and normal in nonoligospermic semen *** increased percentage(>30%)of spermatozoa with noncondensed(“immature”)chromatin was revealed in 2 of 6 nonazoospermic semen samples analyzed by TEM.

关键词： congenital bilateral agenesia/aplasia of vas deferens cystic fibrosis cystic fibrosis transmembrane conductance regulator gene semen spermatozoa

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Auditory ERP Differences in the Perception of Anticipated Speech Sequences in 5 - 6 Years Old Children and Adults

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Journal of Behavioral and Brain Science 2014年第9期4卷 412-422页

作者： portnova galina Martynova Olga Institute of Higher Nervous Activity and Neurophysiology of Russian Academy of Science (IHNA) Moscow Russian Federation Centre for Cognition & Decision Making National Research Institute “Higher School of Economics” Moscow Russian Federation

The perception of complex auditory information such as complete speech sequences develops during human ontogeny. In order to explore age differences in the auditory perception of predictable speech sequences we compared event-related potentials (ERPs) recorded in 5- to 6-year-old children (N = 15) and adults (N = 15) in response to anticipated speech sequences as successive and reverse digital series with randomly omitted digits. The ERPs obtained from the omitted digits significantly differed in the amplitude and latency of the N200 and P300 components between adults and children, the N400 and LPC components were more pronounced in children in the right frontal area for the digits presentation. These findings indicate that the perception of a successive speech structure is less automated in children and requires a detailed analysis of the successive structure and error detection. These differences in auditory ERPs reflect developmental changes in the auditory perception of speech sequences and can serve as indicators of the maturity of cognitive functions in children.

关键词： Event-Related Potentials (ERPs) Emitted Potentials Auditory Information Speech Ontogeny N200 P300 N400

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The EEG Analysis of Auditory Emotional Stimuli Perception in TBI Patients with Different SCG Score

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Open Journal of Modern Neurosurgery 2014年第2期4卷 81-96页

作者： portnova galina Kseniia Gladun Ivanitskii Alexey Institute of Higher Nervous Activity and Neurophysiology of Russian Academy of Science (IHNA) Moscow Russia

The electroencephalographic research has focused on the variety of responses to emotional auditory stimulation in patients at different stages after craniocerebral trauma. The patients sampling consisted of three groups: 13 comatose patients, 14 severe TBI patients, 12 moderate TBI patients, the control group consisting of the 28 healthy adults. The subjects were stimulated with auditory stimuli containing significant sounds (coughing, laughing, crying, bird singing, barking, scraping) and control sounds (white noise). We have analyzed statistically significant differences of power of the rhythmic activity registered during the presentation of different types of stimuli using Matlab. The t-test differences for each type of stimuli and the background were calculated as well as major ANOvA-effects. The results showed that EEG-response was based on the emotional stimuli valence, the consciousness levels, the severity of injury and the recovery process. The TBI patients showed lower theta-rhythm power in the frontal areas in response to the all emotional stimuli. The alpha-activity was reduced in the TBI patients: the alpha-rhythm depression was most vividly pronounced in the control group. The alpha-rhythm acceleration in the occipital areas was found only in the moderate TBI patients and only to the emotional stimuli. The severe TBI and comatose patients showed lower response rates to the neutral stimuli and higher response rates to the unpleasant physiological stimuli.

关键词： Comatose Patients TBI EEG Rhythmic Power Recovery

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Effects of subsampling on characteristics of RNA-seq data from triple-negative breast cancer patients

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Chinese Journal of Cancer 2015年第10期34卷 427-438页

作者： Alexey Stupnikov galina v Glazko Frank Emmert-Streib Computational Biology and Machine Learning Laboratory Faculty of MedicineHealth and Life SciencesSchool of MedicineDentistry and Biomedical SciencesCenter for Cancer Research and Cell BiologyQueen's University Belfast Division of Biomedical Informatics University of Arkansas for Medical Sciences Computational Medicine and Statistical Learning Laboratory Department of Signal ProcessingTampere University of Technology

Background:Data from RNA-seq experiments provide a wealth of information about the transcriptome of an ***,the analysis of such data is very *** this study,we aimed to establish robust analysis procedures that can be used in clinical ***:We studied RNA-seq data from triple-negative breast cancer ***,we investigated the subsampling of RNA-seq ***:The main results of our investigations are as follows:(1) the subsampling of RNA-seq data gave biologically realistic simulations of sequencing experiments with smaller sequencing depth but not direct scaling of count matrices;(2) the saturation of results required an average sequencing depth larger than 32 million reads and an individual sequencing depth larger than 46 million reads;and(3) for an abrogated feature selection,higher moments of the distribution of all expressed genes had a higher sensitivity for signal detection than the corresponding mean ***:Our results reveal important characteristics of RNA-seq data that must be understood before one can apply such an approach to translational medicine.

关键词： RNA-seq data, Computational genomics, Statistical robustness, High-dimensional biology,Triple-negative breast cancer

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On Convergence of MRQI and IMRQI Methods for Hermitian Eigenvalue Problems

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Communications on Applied Mathematics and Computation 2021年第1期3卷 189-197页

作者： Fang Chen Cun-Qiang Miao galina v.Muratova School of Applied Science Beijing Information Science and Technology UniversityBeijing 100192China School of Mathematics and Statistics Central South UniversityChangsha 410083China Laboratory of Computational Mechanics I.I.Vorovich Institute of MathematicsMechanics and Computer ScienceSouthern Federal UniversityRostov-on-Don 344090Russia

Bai et *** the multistep Rayleigh quotient iteration(MRQI)as well as its inexact variant(IMRQI)in a recent work(***.77:2396–2406,2019).These methods can be used to effectively compute an eigenpair of a Hermitian *** convergence theorems of these methods were established under two conditions imposed on the initial guesses for the target eigenvalue and *** this paper,we show that these two conditions can be merged into a relaxed one,so the convergence conditions in these theorems can be weakened,and the resulting convergence theorems are applicable to a broad class of *** addition,we give detailed discussions about the new convergence condition and the corresponding estimates of the convergence errors,leading to rigorous convergence theories for both the MRQI and the IMRQI.

关键词： Hermitian eigenvalue problem MRQI IMRQI Convergence

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The boys are back in town: Rethinking the function of ribosomal DNA repeats in the genomic era

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Molecular Plant 2023年第3期16卷 514-516页

作者： Francesca B.Lopez Peter C.McKeown Antoine Fort galina Brychkova Charles Spillane Genetics and Biotechnology Laboratory Plant&AgriBiosciences Research Centre(PABC)Ryan InstituteUniversity of GalwayH91 REW4 GalwayIreland Present address:Department of Plant Biology and Genome Center University of CaliforniaDavisUC Davis Genome CenterDavisCA 95616USA

Next-generation sequencing technological advances,affording high-throughput,scalable,and fast assemblies,have enabled genome editing techniques that allow us to remove,insert,and modify genes for rapid and precise fun... 详细信息

关键词： remove precise function

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