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Recent advances and future therapy development for Alzheimer’s disease and related disorders

Neural Regeneration Research 2024年第9期19卷 1877-1878页

作者： Megan Hong gal bitan Department of Neurology David Geffen School of MedicineUniversity of California Los AngelesLos AngelesCAUSA Department of Chemistry and Biochemistry University of California Los AngelesLos AngelesCAUSA Molecular Biology Institute University of California Los AngelesLos AngelesCAUSA Brain Research Institute University of CaliforniaLos AngelesCAUSA

Over 55 million people globally live with Alzheimer’s disease(AD)or related dementias(ADRD)and the number is expected to double every twenty *** i l recent l y,onl y symptomatic treatments were available to patients with AD,including acetylcholine esterase inhibitors,of which the last one,galantamine,was approved by the US Food and Drug Administration(FDA)in 2001.

关键词： Alzheimer globally patients

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Toward a biomarker panel measured in CNS-originating extracellular vesicles for improved differential diagnosis of Parkinson’s disease and multiple system atrophy

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Translational Neurodegeneration 2023年第1期12卷 677-680页

作者： Hash Brown Taha Simon Hornung Suman Dutta Leony Fenwick Otmane Lahgui Kathryn Howe Nour Elabed Irish del Rosario Darice Y.Wong Aline Duarte Folle Daniela Markovic Jose-Alberto Palma Un Jung Kang Roy N.Alcalay Miriam Sklerov Horacio Kaufmann Brent L.Fogel Jeff M.Bronstein Beate Ritz gal bitan Department of Neurology David Geffen School of MedicineUniversity of California Los AngelesLos AngelesCA 90095USA Department of Integrative Biology and Physiology University of California Los AngelesLos AngelesCA 90095USA Department of Epidemiology Fielding School of Public HealthUniversity of California Los AngelesLos AngelesCA 90095USA Department of Medicine Statistics Core Division of General Internal Medicine and Health Services ResearchUniversity of California Los AngelesLos AngelesCA 90095USA Department of Neurology Dysautonomia CenterNew York University School of MedicineNew YorkNY 10016USA Department of Neurology Taub Institute for Research on Alzheimer’s Disease and the Aging BrainColumbia UniversityNew YorkNY 10032USA Department of Neurology Tel Aviv Sourasky Medical CenterTel AvivIsrael Department of Neurology University of North Carolina School of MedicineChapel HillNC 27599USA Department of Neurology The Marlene and Paolo Fresco Institute for Parkinson’s and Movement DisordersNew York University School of MedicineNew YorkNY 10016USA Department of Human Genetics David Geffen School of MedicineUniversity of California Los AngelesLos AngelesCA 90095USA UCLA Clinical Neurogenomics Research Center David Geffen School of MedicineUniversity of CaliforniaLos AngelesCA 90095USA Brain Research Institute University of CaliforniaLos AngelesCA 90095USA Molecular Biology Institute University of California Los AngelesLos AngelesCA 90095USA Present Address:Division of Peptide Biochemistry TUM School of Life SciencesTechnical University of Munich85354 FreisingGermany

Synucleinopathies are neurodegenerative diseases char-acterized by accumulation of misfoldedα-synuclein(α-syn)inclusions in neuronal and/or glial *** differences in the underlying pathophysiology,synucle-inopathies ... 详细信息

关键词： diagnosis atrophy diseases

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