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Journal of Geriatric Cardiology 2021年第12期18卷 1058-1062页

作者： gaetano ruocco Guido Pastorini Mauro Feola Cardiology Unit Riuniti of Valdichiana HospitalUSL-SUD-EST ToscanaMontepulcianoSienaItaly Cardiology Unit Regina Montis Regalis HospitalASL-CN1MondovìCuneoItaly

Despite new therapeutic options,patients with heart failure(HF)still progress to advanced *** particular,patients who developed a severe left ventricular(LV)systolic and/or diastolic dysfunction with higher degree of NYHA class,recurrent hospitalizations for HF and showing a severe impairment of exercise capacity were defined as“advanced HF”.[1]Levosimendan was recently approved in order to treat patients hospitalized for acute decompensated HF(ADHF)with severe systolic *** pharmacolo-gical effects of levosimendan consists of inotropy,vasodilatation and cardioprotection increasing of calcium sensitivity.[2]These effects should be mon-itored with echocardiography.[3]In particular,in ad-vanced HF patients,levosimendan showed positive effects in reducing mortality and three months hos-pitalization;about quality of life and symptoms im-provement,levosimendan showed contrasting ef-fect among the studies on advanced HF patients available.

关键词： patients infusion mortality

Effects of a short-term alirocumab administration on the aortic stiffness: preliminary results

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Journal of Geriatric Cardiology 2019年第10期16卷 782-784页

作者： Feola Mauro Ferreri Cinzia Rossi Arianna Testa Marzia ruocco gaetano Francesco Tassone Cardiology Division Ospedale Regina Montis Regalis Mondovi' Italy School of Geriatry Università degli Studi di Torino TorinoItaly Division of Endocrinology Ospedale S. Croce-carleCuneoItaly

Arterial stiffness and wave reflections are widely used in observational studies to analyse the determinants of haemodynamic changes observed in various clinical conditions and to understand the pathogenesis of their cardiovascular complications. A large number of publications and several reviews documented the changes in arterial stiffness and wave reflections after various interventions, either non-pharmacological or pharmacological.

关键词： Alirocumab Aortic stiffness Pulse wave velocity

Hierarchical models for failure analysis of plates bent by distributed and localized transverse loadings

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2008年第5期9卷 600-613页

作者： Erasmo CARRERA gaetano GIUNTA Aeronautic and Space Engineering Department Politecnico di Torino Torino Italy

The failure analysis of simply supported, isotropic, square plates is addressed. Attention focuses on minimum failure load amplitudes and failure locations, von Mises＇ equivalent stress along the plate thickness is also addressed. Several distributed and localized loading conditions are considered. Loads act on the top of the plate. Bi-sinusoidal and uniform loads are taken into account for distributed loadings, while stepwise constant centric and off-centric loadings are addressed in the case of localized loadings. Analysis is performed considering plates whose length-to-thickness ratio a/h can be as high as 100 （thin plates） and as low as 2 （very thick plates）. Results are obtained via several 2D plate models. Classical theories （CTs） and higher order models are applied. Those theories are based on polynomial approximation of the displacement field. Among the higher order theories （HOTs） HOTsa models account for the transverse shear deformations, while HOTs models account for both transverse shear and transverse normal deformations. LHOTs represent a local application of the higher order theories. A layerwise approach is thus assumed： by means of mathematical interfaces, the plate is considered to be made of several fictitious layers. The exact 3D solution is presented in order to determine the accuracy of the results obtained via the 2D models. In this way a hierarchy among the 2D theories is established. CTs provide highly accurate results for a/h greater than 10 in the case of distributed loadings and greater than 20 for localized loadings. Results obtained via HOTs are highly accurate in the case of very thick plates for bi-sinusoidal and centric loadings. In the case of uniform and off-centric loadings a high gradient is present in the neighborhood of the plate top. In those cases, LHOTs yield results that match the exact solution.

关键词： Failure load von Mises' equivalent stress lsotropic plates Higher order theories (HOTs) Exact 3D solution

Editorial:Industrial relevance of molybdenum in China

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Advances in Manufacturing 2020年第1期8卷 35-39页

作者： Tim Outteridge Nicole Kinsman gaetano Ronchi Hardy Mohrbacher International Molybdenum Association LondonUK Department of Materials Engineering KU LeuvenLeuvenBelgium NiobelCon bvba SchildeBelgium

About 80%of all molybdenum mined in the world(not including units recovered via recycling)is used as an alloying element in iron and *** general,the intensity of molybdenum use in China is still lower than in more highly developed regions such as the USA and *** difference is manifest in both carbon steels and stainless steels,suggesting a significant opportunity for more widespread use of molybdenum in the future as China follows its self-reliance policy,calling for more sophisticated *** market development,as being pursued by the International Molybdenum Association(IMOA),is a key asset in that *** article summarizes some key facts on molybdenum mining,use and market development in China.

关键词： China molybdenum industry Global molybdenum reserves Molybdenum applications Enduser markets Molybdenum alloying Market development

Recovery and reuse of abandoned buildings for student housing:A case study in Catania,Italy

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Frontiers of Architectural Research 2018年第4期7卷 510-520页

作者： Stefano Cascone gaetano Sciuto Department of Civil Engineering and Architecture University of CataniaCataniaItaly

Over the past 15 years, housing supply for university students has increased significantly given the considerable attention provided by national institutions on the issue of student housing. In Italy, however, only approximately 4% of students live in university residences. Since 2001, interventions on existing buildings have accounted for approximately 60% of the overall measures proposed for new university residences; these interventions comprise most of the available public economic resources. The possibility of recovering and reusing existing buildings for university residences is remarkable for the city of Catania because most of the students are enrolled in university courses located within the historic city center. Moreover, abandoned buildings are currently a significant part of the city's architectural heritage. This research aims to develop an articulated and integrated set of frameworks to support the various phases of the design process for recovering and then reusing existing buildings as university residences. The proposed approach applies existing dimensional standards and environmental sustainability principles to a constructed building using traditional techniques. (C) 2018 Higher Education Press Limited Company. Production and hosting by Elsevier B.V. on behalf of KeAi.

关键词： University residences Historic center Recovery Reuse Refurbishment Retrofit

Sex ratio variation and sex determination in the mallee dragon Ctenophorus fordi

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Integrative Zoology 2008年第3期3卷 157-165页

作者： Tobias ULLER gaetano ODIERNA Mats OLSSON School of Biological Sciences University of WollongongWollongongNew South WalesAustralia Department of Structural and Functional Biology University of Naples Federico IINaplesItaly

Recent evidence suggests that many Australian agamids show temperature-dependent sex determination(TSD)with variation in sex determining mechanisms among closely related ***,as shown in other vertebrates,sex ratios can also be influenced by genetic or phenotypic differences among females in their propensity to produce sons or daughters,and these influences might confound any thermal effects of incubation per *** address these issues,we investigated the determinants of sex ratios in the mallee dragon Ctenophorus fordi,together with a detailed analysis of *** was no detectable variation in sex ratios arising from variation among females,clutches or incubation temperatures,which might indicate genetic sex determination for this ***,there was no evidence of cytologically distinct sex chromosomes using standard banding *** sex ratio pattern in *** strongly contrasts with the results for the congener Ctenophorus pictus,where sex ratios show variation among ***,Australian agamids offer promising opportunities to address fundamental issues in sex ratio biology.

关键词： genetic-dependent sex determination lizard sex ratio sex allocation temperature-dependent sex determination.

Splenic lymphangiomatosis showing rapid growth during lactation:A case report

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World Journal of Gastroenterology 2010年第9期16卷 1155-1157页

作者： Rosalia Patti Emilio Iannitto gaetano Di Vita General Surgery Unit Department of Surgical and Oncological SciencesUniversity of Palermo Haematological Division University of Palermo

Splenic lymphangiomatosis is a very rare condition that,from 1990 to date,has been described only nine *** the present report,we describe the first case of splenic lymphangiomatosis with rapid growth during lactation in a 35-year-old *** also underline the difficultly in making an accurate preoperative diagnosis,despite more modern imaging *** splenectomy was considered to be the treatment needed,both to make a definitive diagnosis and to exclude the presence of malignancy.

关键词： Lymphangiomatosis Spleen Lactation

The effect of direct-acting antivirals on hepatocellular carcinoma recurrence: still waiting for the turning point

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Hepatobiliary Surgery and Nutrition 2019年第5期8卷 525-526页

作者： gaetano Serviddio Rosanna Villani Liver Unit Centro Universitario per la Ricercaela curadelle Epatopatie(C.U.R.E.)Department of Medical and Surgical SciencesUniversity of FoggiaFoggiaItaly

Hepatocellular carcinoma(HCC)is the fifth most commoncancer worldwide accounting for about 9%of all cancerdeaths(1).The natural history of HCC is extremely variabledue to high effectiveness of treatment only in early ... 详细信息

关键词： cancer turning hepatocellular

liver and the defects of cholesterol and bile acids biosynthesis: rare disorders many diagnostic pitfalls

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World Journal of Gastroenterology 2017年第29期23卷 5257-5265页

作者： gaetano Corso Antonio Dello Russo Monica Gelzo Department of Clinical and Experimental Medicine University of Foggia Department of Molecular Medicine and Medical Biotechnology University of Naples Federico Ⅱ

In recent decades, biotechnology produced a growth of knowledge on the causes and mechanisms of metabolic diseases that have formed the basis for their study, diagnosis and treatment. Unfortunately, it is well known that the clinical features of metabolic diseases can manifest themselves with very different characteristics and escape early detection. Also, it is well known that the prognosis of many metabolic diseases is excellent if diagnosed and treated early. In this editorial we briefly summarized two groups of inherited metabolic diseases, the defects of cholesterol biosynthesis and those of bile acids. Both groups show variable clinical manifestations but some clinical signs and symptoms are common in both the defects of cholesterol and bile acids. The differential diagnosis can be made analyzing sterol profiles in blood and/or bile acids in blood and urine by chromatographic techniques(GC-MS and LC-MS/MS). Several defects of both biosynthetic pathways are treatable so early diagnosis is crucial. Unfortunately their diagnosis is made too late, due either to the clinical heterogeneity of the syndromes(severe, mild and very mild) that to the scarcity of scientific dissemination of these rare diseases. Therefore, the delay in diagnosis leads the patient to the medical observation when the disease has produced irreversible damages to the body. Here, we highlighted simple clinical and laboratory descriptions that can potentially make you to suspect a defect in cholesterol biosynthesis and/or bile acids, as well, we suggest appropriate request of the laboratory tests that along with common clinical features can help to diagnose these defects.

关键词： Cholesterol Bile acids Liver metabolism Gas chromatography coupled to mass spectrometry Liquid chromatography coupled to tandem mass spectrometry

A Tabu-search-based Algorithm for Distribution Network Restoration to Improve Reliability and Resiliency

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Journal of Modern Power Systems and Clean Energy 2023年第1期11卷 302-311页

作者： Alessandro Bosisio Alberto Berizzi Daniele Lupis Andrea Morotti gaetano Iannarelli Bartolomeo Greco Energy Department of Politecnico di Milano MilanItaly E-distribuzione MonzaItaly Unareti Electrical Network Planning Department MilanItaly Department of Astronautics Electrical and Energy Engineering of the Sapienza UniversityRomeItaly Technological Development Department of the DSO Unareti MilanItaly Unareti Market Development and Special Projects Department MilanItaly IEEE

Fault restoration techniques have always been crucial for distribution system operators(DSOs).In the last decade,it started to gain more and more importance due to the introduction of output-based regulations where DSO performances are evaluated according to frequency and duration of energy supply *** paper presents a tabu-searchbased algorithm able to assist distribution network operational engineers in identifying solutions to restore the energy supply after permanent *** to the network property,two objective functions are considered to optimize either reliability or *** mathematical formulation includes the traditional feeders,number of switching operation limit,and radiality *** to the DSO of Milan,Unareti,the proposed algorithm has been tested on a real distribution network to investigate its effectiveness.

关键词： Distribution system operators(DSOs) heuristic algorithms power system reliability power system restoration resiliency