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Prevalence of Psittacine Beak and Feather Disease Virus and Avian Polyomavirus in Captivity Psittacines from Costa Rica

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Open Journal of Veterinary Medicine 2013年第4期3卷 240-245页

作者： Gaby Dolz Jessica Sheleby-Elías Juan J.Romero-Zuniga Bernardo Vargas-Leiton Gustavo Gutiérrez-Espeleta Kenneth Madriz-Ordenana Laboratorio de Entomología y Medicina Poblacional Programa MEDPOBEscuela de Medicina VeterinariaUniversidad NacionalHerediaCosta Rica Maestría en Enfermedades Tropicales Posgrado Regional en Ciencias Veterinarias TropicalesEscuela de Medicina VeterinariaUniversidad NacionalHerediaCosta Rica Escuela de Biología Universidad de Costa RicaSan JoseCosta Rica Biotécnica Análisis Moleculares San JoseCosta Rica

Psittacine beak and feather disease virus (PBFDV) and avian polyomavirus (APV) are the most common viral diseases in psittacine birds, both affecting feathers and physical appearance of birds. Between 2005 and 2009, a total of 269 samples were collected from birds presented at veterinary clinics, shelters and rescue centers of wildlife in Costa Rica. They belonged to 19 species of psittacine birds. The most representative species in the sample were Ara macao (157), Ara ambigua (37), Amazona autumnalis (24), Amazon ochrocephala (21) and Ara ararauna (8). A prevalence of 19.7% (53/269) for PBFDV and 4.8% (13/269) for APV was determined using Polymerase Chain Reaction (PCR). In 3.3% (9/269) of the birds mixed infections were detected. Statistical analysis determined that psittacines living in shelters and rescue centers had a greater risk to be positive to PBFDV and APV than birds that were presented at veterinary clinics, while only for PBFDV it was determined, that it is more likely to detect it in feathers than in blood. Finally, birds infected with PBFDV had 6.24 times more probability to become infected with APV, than non-infected birds. This is the first report of prevalence of PBFDV and APV in captive psittacines from Costa Rica.

关键词： Psittacine Beak and Feather Disease Virus Avian Polyomavirus Psittacine Birds Costa Rica

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Evaluation of a Voluntary Control Program for the Detection of Bovine Leukemia Virus Antibodies Based on Agar Gel Immunodiffusion Test in Dairy Farms in Costa Rica

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Open Journal of Veterinary Medicine 2015年第12期5卷 229-233页

作者： Gaby Dolz Francine Huijsen Carlos Jiménez Luis L. Rodríguez Escuela de Medicina Veterinaria Universidad Nacional Heredia Costa Rica

Cattle from 20 dairy farms were serologically tested over a five-year period using agar gel immunodiffusion test (AGIDT) as part of a voluntary Bovine Leukemia Virus (BLV) control program. After five years of removing infected animals from the herds based on BLV-AGIDT serological status, blood samples from 332 cattle in these farms were collected and analyzed side by side by AGIDT and enzyme-linked immunosorbent assay (ELISA) to detect antibodies against BLV. AGIDT detected 29.2% (97) and 16.0% (53) of the animals as positive and weak positive respectively, whereas ELISA detected 58.2% (193) cattle as positive. The prevalence of BLV-antibodies determined with AGIDT in the dairy farms oscillated between 0% and 86%, whereas prevalence determined by ELISA ranged between 28% and 100% in the same farms. Although both techniques showed similarly results in farms with high BLV-prevalence, ELISA detected a larger proportion of BLV-positive, especially in farms with low or no BLV-prevalence based on AGIDT, leading to wrong assumptions in terms of farm level control efforts. Our results strongly suggest that AGIDT alone is inadequate to implement BLV control programs and ELISA is a more adequate test for BLV surveillance and control programs.

关键词： BLV Serological Testing Control Programs

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Understanding Ehrlichia canis Infections in Dogs of Costa Rica: Hematological Findings and Indicative Clinical Signs

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Open Journal of Veterinary Medicine 2016年第11期6卷 163-175页

作者： Alexander V. Barrantes-González Ana E. Jiménez-Rocha Juan José Romero-Zuñiga Gaby Dolz Programa de Investigación en Medicina Poblacional Escuela de Medicina Veterinaria Universidad Nacional Heredia Costa Rica Laboratorio de Parasitología Escuela de Medicina Veterinaria Universidad Nacional Heredia Costa Rica

Background: A cross-sectional study combining different serological and molecular techniques for the detection of Ehrlichia canis in dogs was carried out to determine hemopathological findings and suggestive clinical signs associated with acute, subclinical and chronic infections in the dog population of Costa Rica. Objectives: The present study describes and analyzes, in a more representative sampling frame, the clinical and hematological presentation of E. canis infection in dogs of Costa Rica in all its clinical stages. Methods: A descriptive analysis of the clinical signs was performed from a 441-dog sample. Serological and molecular techniques for the detection of Ehrlichia canis in dogs were applied. One and two-way ANOVA were carried out to determine the effect of the infection status on the hematological parameters. Results: A total of 0.7% (3/407) dogs were found with acute (seronegative but PCR positive), 29.7% (121/407) with subclinical (seropositive and PCR negative), and 2.5% (10/407) with chronic (seropositive and PCR positive) E. canis infections. Significant hemopathological findings were determined in dogs with acute (thrombocytosis), subclinical and chronic (anemia, thrombocytopenia, leukopenia) E. canis infections. Conclusions: Future studies must determine if dogs with subclinical E. canis infections eliminated the agent without any medication, or if they continue to be persistently infected, and will develop the chronic disease at some point in their lives.

关键词： Ehrlichiosis Epidemiology Hematopathology Infectious Disease Clinical Pathology

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A Conditional Generative adversarial Network for energy use in multiple buildings using scarce data

能源与人工智能(英文)

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能源与人工智能(英文) 2021年第3期5卷 119-132页

作者： gaby Baasch Guillaume Rousseau Ralph Evins Energy and Cities Group Department of Civil EngineeringUniversity of VictoriaCanada

Building consumption data is integral to numerous applications including retrofit analysis,Smart Grid integration and optimization,and load forecasting.Still,due to technical limitations,privacy concerns and the proprietary nature of the industry,usable data is often unavailable for research and development.Generative adversarial networks(GANs)-which generate synthetic instances that resemble those from an original training dataset-have been proposed to help address this issue.Previous studies use GANs to generate building sequence data,but the models are not typically designed for time series problems,they often require relatively large amounts of input data(at least 20,000 sequences)and it is unclear whether they correctly capture the temporal behaviour of the buildings.In this work we implement a conditional temporal GAN that addresses these issues,and we show that it exhibits state-of-the-art performance on small datasets.22 different experiments that vary according to their data inputs are benchmarked using Jensen-Shannon divergence(JSD)and predictive forecasting validation error.Of these,the best performing is also evaluated using a curated set of metrics that extends those of previous work to include PCA,deep-learning based forecasting and measurements of trend and seasonality.Two case studies are included:one for residential and one for commercial buildings.The model achieves a JSD of 0.012 on the former data and 0.037 on the latter,using only 396 and 156 original load sequences,respectively.

关键词： Generative adversarial network Building load profile Machine learning Data scarcity

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以色列理工学院研究生村——以色列海法

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世界建筑导报 2023年第3期38卷 110-113页

作者： Gidi Bar Orian gaby Schwartz Schwartz Besnosoff建筑师事务所 Bar Orian建筑师事务所

以色列理工学院研究生村位于以色列理工学院的正门附近,面积为22德南(22,000平方米),包括215套住宅单元,从2室到4室不等。该村还将设置一个带有学前课堂的社区中心和一个多功能厅,作为村中居民和非住校研究生的社交中心。项目设计依据... 详细信息

以色列理工学院研究生村位于以色列理工学院的正门附近,面积为22德南(22,000平方米),包括215套住宅单元,从2室到4室不等。该村还将设置一个带有学前课堂的社区中心和一个多功能厅,作为村中居民和非住校研究生的社交中心。项目设计依据的是景观敏感和生态规划的原则。具体表现为:对景观的破坏最小、尽可能少的开发作业、保护现有的自然环境,以及创造一个能融入自然环境的轮廓。

关键词：研究生住宅单元自然环境生态规划多功能厅住校设计依据以色列

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Synthesis of Water-soluble, Polyester-based Dendrimer Prodrugs for Exploiting Therapeutic Properties of Two Triterpenoid Acids

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Chinese Journal of Polymer Science 2018年第9期36卷 999-999,1000-1010页

作者： Silvana Alfei gaby Brice Taptue Silvia Catena Angela Bisio Dipartimento di Farmacia Sezione di Chimica e Tecnologie Farmaceutiche e Alimentari Università di Genova

Dendrimers are macromolecules characterized by high controlled size, shape and architecture, presence of inner cavities able to accommodate small molecules and many peripheral functional groups to bind target entities. They are of eminent interest for biomedical applications, including gene transfection, tissue engineering, imaging, and drug delivery. The well-known pharmacological activities of ursolic and oleanolic acids are limited by their small water solubility, non-specific cell distribution, low bioavailability, poor pharmacokinetics, and their direct administration could result in the release of thrombi. To overcome such problems, in this paper we described their physical incorporation inside amino acids-modified polyester-based dendrimers which made them highly water-soluble. IR, NMR, zeta potential, mean size of particles, buffer capacity and drug release profiles of prepared materials were reported. The achieved water-soluble complexes harmonize a polycationic character and a buffer capacity which presuppose efficient cell penetration and increased residence time with a biodegradable cell respectful scaffold, thus appearing as a promising team of not toxic prodrugs for safe administration of ursolic and oleanolic acids.

关键词： Polyester-based amino acids-modified dendrimers Physical encapsulation Water-soluble dendriplexes Buffer capacity NMR investigations

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MISTY LIGHT美发沙龙

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现代装饰 2022年第2期 164-167页

作者： gaby Teng 杨文彩无不详 DPD递加设计

空间的灵感来源于雾光,朦胧又神秘。艺术装置与空间氛围戏剧性地碰撞在一起,独特的艺术装置、色彩和光线共同创造了微妙的效果,塑造出空间的精神与内核。迷雾若隐若现游离于空间之中,在结构与光影之间产生美与吸引力,使人前往与探索。... 详细信息

空间的灵感来源于雾光,朦胧又神秘。艺术装置与空间氛围戏剧性地碰撞在一起,独特的艺术装置、色彩和光线共同创造了微妙的效果,塑造出空间的精神与内核。迷雾若隐若现游离于空间之中,在结构与光影之间产生美与吸引力,使人前往与探索。项目地址位于深圳皇庭广场,皇庭广场是深圳CBD的钻石之心,为高端及中端国际品牌的旗舰店,店铺门面开阔,采光充足,周边人流量高。设计师在满足美业常规需求之后,试图打破传统发廊的固有模式,在空间中注入新的艺术手法。以装置性的弧形构造,消解了原有空间的规则感,虚虚实实中改变了视觉焦点,同时构成了人与空间交流的新介质。

关键词：视觉焦点空间氛围国际品牌弧形构造项目地址旗舰店人流量

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伊斯卡智慧铣铝策略

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今日制造与升级 2021年第9期 28-29页

作者： gaby Zehavi Andrei Petrilin 伊斯卡

前言铣铝加工看上去是一个非常容易的加工过程。通常,是那些不直接参与铝加工的人们持此错误观点。他们相信,采用经动平衡的、锋利的、经抛光处理的刀具并以最大转速旋转设置中等进给速度,就已经足以像切黄油那样轻松地切削铝材了。

关键词：抛光处理最大转速铝加工加工过程进给速度动平衡错误观点

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伊斯卡智慧铣铝策略

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汽车工艺师 2021年第11期 23-24页

作者： gaby Zehavi Andrei Petrilin ISCAR伊斯卡中国中国上海201108

铝加工特性相比于钢的加工,铝及铝合金所需的切削力更小,因此铣刀切削刃承受的机械负荷相对较低。在本文中,将铝及铝合金简称为“铝”。铝具有高导热系数,因此铝加工过程生成的切屑传导出大量的切削热,其结果是显著降低作用于切削刃的... 详细信息

铝加工特性相比于钢的加工,铝及铝合金所需的切削力更小,因此铣刀切削刃承受的机械负荷相对较低。在本文中,将铝及铝合金简称为“铝”。铝具有高导热系数,因此铝加工过程生成的切屑传导出大量的切削热,其结果是显著降低作用于切削刃的热载荷。源于以上属性,铣铝具有超高切削速度及进给的特征。然而,这并不能确保铣铝加工就会非常轻松。

关键词：铝及铝合金高切削速度切削刃铝加工切削热切削力导热系数机械负荷

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智慧铣削铝及铝合金策略

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金属加工（冷加工） 2021年第10期 15-16页

作者： gaby Zehavi Andrei Petrilin 伊斯卡刀具国际贸易(上海)有限公司上海201108

基于铝及铝合金材料加工的特性,介绍了伊斯卡为实现高效高速加工、高金属去除率、易于排屑以及更好的抗振性等,精心设计和开发的多款铣刀系列产品。

关键词：铣削铝铝合金铣刀加工刀具

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