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World Journal of Gastroenterology 2024年第17期30卷 2308-2310页

作者： Veronika Papp Pál Miheller Department of Surgery Transplantation and GastroenterologySemmelweis UniversityBudapest 1082Hungary

Gastric cystica profunda(GCP)is an uncommon but underestimated gastric *** precancerous potential determines its *** addition to previous mucosa injury due to operations,biopsy or polypectomy,chronic active and atrophic gastritis may also lead to the development of *** carefully examining the stomach and taking biopsy samples from the susceptible regions,the stage of atrophy can be *** atrophic gastritis is a risk factor for cancer evolvement and it can also contribute to GCPs *** frequently occur close to early gastric cancers(EGCs)or EGC can arise from the cystic *** resection is an effective and minimally invasive treat-ment in GCP.

关键词： Gastric cystica profunda Chronic active gastritis Atrophic gastritis Operative link for Gastritis Assessment staging Early gastric cancer Endoscopic resection

long-term follow-up of patients with congenital diaphragmatic hernia

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World Journal of Pediatric Surgery 2024年第2期7卷 100-109页

作者： Nicole Cimbak Terry l Buchmiller Department of Pediatric Surgery Boston Children's HospitalBostonMAUSA

Neonates with congenital diaphragmatic hernia encounter a number of surgical and medical morbidities that persist into *** mortality improves for this population,these survivors warrant specialized follow-up for their unique disease-specific *** congenital diaphragmatic hernia clinics are best positioned to address these complex long-term morbidities,provide long-term research outcomes,and help inform standardization of best practices in this cohort of *** review outlines long-term morbidities experienced by congenital diaphragmatic hernia survivors that can be addressed in a comprehensive follow-up clinic.

关键词： hernia congenital patients

Time trends and outcomes of gastrostomy placement in a Swedish national cohort over two decades

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World Journal of Gastroenterology 2024年第10期30卷 1358-1367页

作者： Martin löfling Skogar Magnus Sundbom Department of Surgical Sciences Uppsala UniversityUppsala 75185Sweden

BACKGROUND Percutaneous endoscopic gastrostomy(PEG)and laparoscopically inserted gastrostomy have become the gold standard for adult patients and children,respectively,requiring long-term enteral nutrition ***-related mortality is a rare event,often reported to be zero in smaller *** data on 30-d mortality and long-term survival rates after gastrostomy placement are scarce in the *** To study the use of gastrostomies in Sweden from 1998-2019 and to analyze procedure-related mortality and short-term(long-term *** In this retrospective,population-based cohort study,individuals that had received a gastrostomy between 1998-2019 in Sweden were *** were identified in the Swedish National Patient Register,and survival analysis was possible by cross-referencing the Swedish Death *** cohort was divided into three age groups:Children(0-18 years);adults(19-64 years);and elderly(≥65 years).Kaplan-Meier with log-rank test and Cox regression were used for survival *** In total 48682 individuals(52%males,average age 60.9±25.3 years)were *** cohort consisted of 12.0%children,29.5%adults,and 58.5%*** increased use of gastrostomies was observed during the study period,from 13.7/100000 to 22.3/100000 individuals(Pled(about 800 to 1800/year),with a corresponding decrease in open gastrostomy(about 700 to 340/year).laparoscopic gastrostomy increased more than ten-fold(about 20 to 240/year).Overall,PEG,open gastrostomy,and laparoscopic gastrostomy constituted 70.0%(n=34060),23.3%(n=11336),and 4.9%(n=2404),***-related mortality was 0.1%(n=44)overall(PEG:0.05%,open:0.24%,laparoscopic:0.04%).The overall 30-d mortality rate was 10.0%(PEG:9.8%,open:12.4%,laparoscopic:1.7%)and decreased from 11.6%in 1998-2009 vs 8.5%in 2010-2019(Pl rates for children,adults,and elderly were 93.7%,67.5%,a

关键词： Gastrostomy Percutaneous endoscopic gastrostomy Dysphagia Enteral nutrition long-term Survival Complication

Robust Optimal Framework for Doubly Fed Induction Generator with Uncertain Dynamics

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Protection and Control of Modern Power Systems 2024年第5期9卷 129-141页

作者： Yongfeng lü Xiaowei Zhao Priyank Shah College of Electrical and Power Engineering Taiyuan University of TechnologyTaiyuan 030024China Intelligent Control and Smart Energy(ICSE)Research Group School of EngineeringThe University of WarwickCoventry CV47ALUK

A robust optimal framework is designed herein to mitigate the oscillatory dynamics in a doubly fed induction generator(DFIG)even in the presence of network disturbances and input *** address uncertain dynamics,herein,a novel transformation formula is developed for a wind energy conversion *** unscented Kalman filter is applied to estimate the un-measured internal states of the wind energy conversion system using terminal *** detailed convergence and stability analyses of the presented framework are investigated to validate its ***,comparative modal analyses are carried out to demonstrate the improvement in the damping of critical low-frequency oscillatory modes using the presented *** simulation results demonstrate satisfactory performance under various operating scenarios,such as increasing and decreasing wind speed and varying the terminal *** comparative performance is demonstrated to validate the effectiveness of the presented framework over that of the state-of-the-art *** Terms—Optimal control,power system,renew-able energy sources,wind energy conversion system,doubly fed induction generator.

关键词： Optimal control power system renew-able energy sources wind energy conversion system doubly fed induction generator

Immune pathway through endometriosis to ovarian cancer

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World Journal of Clinical Oncology 2024年第4期15卷 496-522页

作者： Mariana Santos Calmon Fabian Fellipe Bueno lemos Marcel Silva luz Samuel luca Rocha Pinheiro luis Guilherme de Oliveira Silva gabriel lima Correa Santos gabriel Reis Rocha Fabrício Freire de Melo Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029-094BahiaBrazil

Endometriosis is an estrogen-dependent inflammatory disease,defined by the presence of functional endometrial tissue outside of the uterine *** disease is one of the main gynecological diseases,affecting around 10%-15%women and girls of reproductive age,being a common gynecologic *** endometriosis is a benign disease,it shares several characteristics with invasive *** support that it has been linked with an increased chance of developing endometrial ovarian cancer,representing an earlier stage of neoplastic *** is particularly true for women with clear cell carcinoma,low-grade serous carcinoma and ***,the carcinogenic pathways between both pathologies remain poorly *** studies suggest a connection between endometriosis and endometriosis-associated ovarian cancers(EAOCs)via pathways associated with oxidative stress,inflammation,and *** article aims to review current data on the molecular events linked to the development of EAOCs from endometriosis,specifically focusing on the complex relationship between the immune response to endometriosis and cancer,including the molecular mechanisms and their *** recent developments in immunotherapy and their potential to boost the effectiveness of future treatments.

关键词： Ovarian neoplasms Endometriosis Endometriosis-associated ovarian cancers Immune response Immunotherapy

Tomographic reconstruction of the Earth’s magnetosheath from multiple spacecraft:a theoretical study

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Earth and Planetary Physics 2024年第1期8卷 204-214页

作者： A.M.Jorgensen Tianran Sun Y.Huang l.li R.Xu l.Dai Chi Wang New Mexico Institute of Mining and Technology SocorroNMUSA National Space Science Center Chinese Academy of SciencesBeijing 100190China Tsinghua University Beijing 100084China

Following our earlier work on tomographic reconstruction of the magnetosheath soft X-ray emissions with superposed epoch analysis of many images recorded from a single spacecraft we now explore the instantaneous reconstruction of the magnetosheath and magnetopause using a few images recorded simultaneously from a few *** work is motivated by the prospect of possibly having two or three soft X-ray imagers in space in the coming years,and that many phenomena which occur at the magnetopause boundary,such as reconnection events and pressure pulse responses,do not lend themselves as well to superposed epoch *** the reconstruction is successful-which we demonstrate in this paper that it can be-this collection of imagers can be used to reconstruct the magnetosheath and magnetopause from a single image from each spacecraft,allowing for high time resolution *** this paper we explore the reconstruction using,two,three,and four *** show that the location of the subsolar point of the magnetopause can be determined with just two satellites,and that volume emissions of soft X-rays,and the shape of the boundary,can be reconstructed using three or more satellites.

关键词： magnetosheath tomography soft X-ray imaging SMIlE

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Toxicity of a seafood toxin， domoic acid， in the retina via modulation of the NRF2 and NF-κB pathways

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Food Science and Human Wellness 2024年

作者： gabriel Mbuta Tchivelekete Yanqun Cao Mohammad Almarhoun Xinzhi Zhou Agostinho Francisco Cachapa Sebasti?o Tumitangua James Reilly Patricia E.Martin Xinhua Shu Department of Biological and Biomedical Sciences， Glasgow Caledonian University Department of Marine Biology， Faculty of Natural Science， University of Namibe Puai Medical School， Shaoyang University Department of Vision Science， Glasgow Caledonian University

Domoic acid (DA)， a biotoxin， is produced by several species of marine dinoflagellate and diatom during harmful algal bloom events. DA is a neurotoxin， in humans and non-human primates， oral exposure to DA results in gastrointestinal effects， while DA at higher doses leads to neurological symptoms， seizures and memory deficiency. Exposure of humans to DA occurs mainly through consumption of contaminated seafoods containing an accumulation of the toxin. Previously， it was unclear if DA can have toxic effects on the retina. We assessed the toxicity of DA in human retinal cells (ARPE-19) and in zebrafish embryos. DA significantly lowered ARPE-19 cell viability dose-dependently， and decreased anti-oxidative capacity， increased inflammation， and promoted cell death， possibly through modulating the NRF2 and NF-κB signalling pathways. Zebrafish embryos exposed to DA for four days from one day post fertilization (dpf) had an increase in mortality and a decrease in both hatching and heartbeat rate and exhibited morphological abnormalities. DA treatment also significantly downregulated expression of antioxidant genes and upregulated expression of inflammation mediators， as well as causing photoreceptor death in zebrafish embryos. The results demonstrate that consuming seafood containing DA will have potential toxic effects in human retinas.

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Experimental implementation of phase triplicator gratings in a spatial light modulator

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Chinese Optics letters 2024年第2期22卷 64-69页

作者：高尚 María del Mar Sánchez-lópez Ignacio Moreno Instituto de Bioingeniería Universidad Miguel HernándezElche 03202Spain Departamento de Física Aplicada Universidad Miguel HernándezElche 03202Spain Departamento de Ciencia de Materiales Óptica y Tec.Electr´onicaUniversidad Miguel HernándezElche 03202Spain

In this work,we compare different methods for implementing a triplicator,a phase grating that generates three equiintense diffraction *** design with optimal efficiency features a continuous phase profile,which cannot be easily reproduced,and is typically affected by *** compare its performance with binary and sinusoidal phase *** also analyze the effect of quantizing the phase ***,a random approach is adopted to eliminate the additional harmonic *** all cases,a liquid-crystal-on-silicon spatial light modulator is employed to experimentally verify and compare the different approaches.

关键词： diffraction gratings phase modulation triplicator spatial light modulators

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Petrologic evolution of the Gysian ophiolitic serpentinites,NW Iran

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Acta Geochimica 2024年第5期43卷 996-1011页

作者： Monir Modjarrad Donna l.Whitney Hadi Omrani Department of Geology Faculty of SciencesUrmia UniversityUrmiaIran Department of Earth and Environmental Sciences University of MinnesotaMinneapolisMNUSA Department of Geology Faculty of SciencesGolestan UniversityGorgānIran

The Gysian ophiolite of NW Iran is located at the intersection of the ophiolite belts of SE Turkey,NE Iraq,and Iran,and provides the opportunity to investigate the preserved subduction and obduction history of an important tectonic site that has not previously been *** serpentinized peridotites of the Gysian ophiolite contain the assemblagelizardite+chrysotile+spinel/Mg-spinelwith relict clinopyroxene(diopside)and very rare relict orthopyroxene and *** compositions of clinopyroxenes and spinels are more consistent with the formation of the inferred protolithharzburgitesinafore-arcorsupra-subduction zone instead of an abyssal *** Gysian ophiolite is a remnant of the Neo-Tethyan arc-ophiolitic system and records shallow subduction(late Cretaceous to Paleocene beforeobductionalongthrustfaultsoverthecontinental *** review the spatial trends of the metamorphic grade of the Neo-Tethyan ophiolites in this region and provide detailed information about the petrology and mineral chemistry of the Gysian ophiolite.

关键词： Ophiolite Neo-Tethyan Gysian Serpentinite Iran

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Exploring the mechanical behavior and microstructure of compacted loess subjected to dry-wet cycles and chemical contamination

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第9期16卷 3673-3695页

作者： Yongpeng Nie Wankui Ni Xiangfei lü Wenxin Tuo College of Geological Engineering and Geomatics Chang'an UniversityXi'an710054China Department of Civil Engineering Nagoya Institute of TechnologyNagoya466-8555Japan School of Water and Environment Chang'an UniversityXi'an710054China

Due to climatic factors and rapid urbanization,the soil in the loess Plateau,China,experiences the coupled effects of dry-wet cycles and chemical *** the mechanical behavior and corresponding microstructural evolution of contaminated loess subjected to dry-wet cycles is essential to elucidate the soil degradation ***,direct shear and consolidation tests were performed to investigate the variations in mechanical properties of compacted loess contaminated with acetic acid,sodium hydroxide,and sodium sulfate during dry-wet *** mechanical response mechanisms were investigated using zeta potential,mineral chemical composition,and scanning electron microscopy(SEM)*** results indicate that the mechanical deterioration of sodium hydroxidecontaminated loess during dry-wet cycles decreases with increasing contaminant concentration,which is mainly attributed to the thickening of the electrical double layer(EDl)by Nat and the precipitation of calcite,as well as the formation of colloidal flocs induced by OH,thus inhibiting the development of large pores during the dry-wet *** contrast,the attenuation of mechanical properties of both acetic acid-and sodium sulfate-contaminated loess becomes more severe with increasing contaminant concentration,with the latter being more particularly *** is primarily due to the reduction of the EDl thickness and the erosion of cement in the acidic environment,which facilitates the connectivity of pores during dry-wet ***,the salt expansion generated by the drying process of saline loess further intensifies the structural ***,the mechanical performance of compacted loess is sensitive to both pollutant type and concentration,exhibiting different response patterns in the dry-wet cycling condition.

关键词： Contaminated loess Dry-wet cycles Compressibility Shear strength Microstructural evolution