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Percutaneous decannulation of extracorporeal membrane oxygenation using MANTA device:A real-world single-center experience

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World Journal of Cardiology 2024年第10期16卷 574-579页

作者： Ioannis Milioglou Alice Qian Pedro Rafael Vieira de Oliveira Salerno gabriel tensol rodrigues pereira Luis Augusto Palma Dallan Kelsey E Gray Michael Morrison Yasir Abu-Omar Mohammad Eldiasty Cristian Baeza Department of Cardiology University Hospitals Cleveland Medical CenterClevelandOH 44106United States Department of Surgery University Hospitals Cleveland Medical Center and Case Western Reserve University School of MedicineClevelandOH 44106United States

BACKGROUND The MANTA vascular closure device(VCD)represents a novel approach to achieving hemostasis after large-bore femoral access *** clinical studies have evaluated the efficacy of the MANTA device across a range of patient populations undergoing different ***,there is still a paucity of data available concerning the use of MANTA devices in aiding the decannulation of venoarterial extracorporeal membrane oxygenation(VAECMO).AIM To present our single-center experience of utilizing the MANTA VCD in patients undergoing this *** This single-center study included all patients undergoing percutaneous decannulation of femoral VA-ECMO using the MANTA plug-based VCD between January 2021 and October 2023 at University Hospitals Cleveland Medical *** criteria were adult patients who required prolonged(>24 hours)hemodynamic support with *** included all-cause mortality,hemostasis,bleeding,limb ischemia,and site *** This is a retrospective cohort study of 19 patients with a mean age of 56.8 *** of them were males with a mean body mass index of *** most common extracorporeal membrane oxygenation indication was acute coronary syndrome complicated by cardiogenic shock at 36.8%.The mean length of intensive care unit stay for these patients was 18.8±8.42 *** out of 19 patients survived to *** MANTA device was successfully deployed in 19 patients,with 10 procedures conducted at the bedside and 9 in an operating room *** hemostasis was achieved within 5 minutes of MANTA deployment in 17 out of 19 *** 2 patients manual compression after Manta deployment was required to achieve adequate ***,acute lower extremity ischemia was noted in two patients,necessitating endovascular *** infections were reported at the site of MANTA *** Overall,based on our experience and that of other centers,the MANTA VCD

关键词： Extracorporeal membrane oxygenation MANTA Decannulation Hemostasis Ischemia

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Transarterial embolization is an acceptable bridging therapy to hepatocellular carcinoma prior to liver transplantation

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World Journal of Transplantation 2024年第2期14卷 126-134页

作者： gabriel Lazzarotto-da-Silva Leandro A Scaffaro Mauricio Farenzena Lucas Prediger Rafaela K Silva Flávia Heinz Feier Tomaz J M Grezzana-Filho Pablo D rodrigues Alexandre de Araujo Mario Reis Alvares-da-Silva Roberta C Marchiori Cleber Rosito Pinto Kruel Marcio Fernandes Chedid Department of Liver Transplant and Hepatobiliary Surgery Unit Hospital de Clínicas de Porto AlegrePorto Alegre 90035-007Brazil Department of Interventional Radiology Unit Hospital de Clínicas de Porto AlegrePorto Alegre 90035-007Brazil Department of Gastroenterology and Hepatology Hospital de Clínicas de Porto AlegrePorto Alegre 90035-007Brazil

BACKGROUND Hepatocellular carcinoma(HCC)is an aggressive malignant neoplasm that requires liver transplantation(LT).Despite patients with HCC being prioritized by most organ allocation systems worldwide,they still have to wait for long *** therapies(LRTs)are employed as bridging therapies in patients with HCC awaiting *** largely used in the past,transarterial embolization(TAE)has been replaced by transarterial chemoembolization(TACE).However,the superiority of TACE over TAE has not been consistently shown in the *** To compare the outcomes of TACE and TAE in patients with HCC awaiting *** All consecutive patients with HCC awaiting LT between 2011 and 2020 at a single center were *** patients underwent LRT with either TACE or *** patients also underwent percutaneous ethanol injection(PEI),concom-itantly or in different treatment *** choice of LRT for each HCC nodule was determined by a multidisciplinary *** primary outcome was waitlist dropout due to tumor progression,and the secondary outcome was the occurrence of adverse *** the subset of patients who underwent LT,complete pathological response and post-transplant recurrence-free survival were also *** Twelve(18.5%)patients in the TACE group(only TACE and TACE+PEI;n=65)and 3(7.9%)patients in the TAE group(only TAE and TAE+PEI;n=38)dropped out of the waitlist due to tumor progression(P log-rank test=0.29).Adverse events occurred in 8(12.3%)and 2(5.3%)patients in the TACE and TAE groups,respectively(P=0.316).Forty-eight(73.8%)of the 65 patients in the TACE group and 29(76.3%)of the 38 patients in the TAE group underwent LT(P=0.818).Among these patients,complete pathological response was detected in 7(14.6%)and 9(31%)patients in the TACE and TAE groups,respectively(P=0.145).Post-LT,HCC recurred in 9(18.8%)and 4(13.8%)patients in the TACE and TAE groups,respectively(P=0.756).Posttransplant recurrence-free survival was simila

关键词： Hepatocellular carcinoma Transarterial embolization Transarterial chemoembolization Liver transplantation Locoregional therapy Bridging

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Foliar application of rare earth elements on soybean(Glycine max(L)):Effects on biometrics and characterization of phytotoxicity

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Journal of Rare Earths 2020年第10期38卷 1131-1139,I0005页

作者： Eduardo S.rodrigues gabriel S.Montanha Joao P.R.Marques Eduardo de Almeida Lauren N.M.Yabuki Amauri A.Menegario Hudson W.pereira de Carvalho Laboratory of Nuclear Instrumentation(LIN) Center for Nuclear Energy in Agriculture(CENA)University of Sao Paulo(USP)PiracicabaSP13416-000Brazil Environmental Studies Center Sao Paulo State University(UNESP)Rio ClaroSP13506-900Brazil

This study aims at investigating the effects of foliar application of aqueous solutions of La3+and Ce3+nitrates on soybean plants(Glycine max).First,we observe that Triton HW 1000 surfactant at 0.01 vol%reduces droplets contact angle and increases their drying *** greenhouse conditions,the foliar treatments do not affect chlorophyll content,plant height,number of leaves,number of pods,number of seeds per pod,and average seed ***,the treatments induce phytotoxicity since foliar injuries appear after the *** X-ray fluorescence spectroscopy combined to scanning electron microscopy shows that the leaf lesions are positively correlated to accumulation of Ce and La on the leaf surface and also promote structural alteration to the epidermal cells.X-ray absorption near edge structure shows that the La and Ce nitrates are partially bio transformed into oxides by the leaves which might explain the harmful effects.

关键词： Leaf fertilization Rare earth elements Soybean X-ray fluorescence spectroscopy X-ray absorption spectroscopy

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Gastric neuroendocrine tumor: A practical literature review

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World Journal of Gastrointestinal Oncology 2020年第8期12卷 850-856页

作者： gabriel Antonio Roberto Carolina Magalhães Britto rodrigues Renata D’Alpino Peixoto Riad Naim Younes Bachelor Medicine União das Faculdades dos Grandes LagosSão Josédo Rio Preto15030070Brazil Department of Oncology Hospital Alemão Oswaldo CruzSão Paulo 01327001Brazil Universidade Nove de Julho São Paulo 01327001Brazil Department of Thoracic Surgery Hospital Alemão Oswaldo CruzSão Paulo 01327001Brazil

Gastric neuroendocrine tumors are gastric neoplasms originating from enterochromaffin type cells and are inserted in a larger group,named gastroenteropancreatic neuroendocrine *** are considered rare and variable in terms of their clinical,morphological and functional characteristics and may be indolent or *** are classified into types I,II and III,according to their pathophysiology,behavior and *** diagnosis occurs,in most cases,incidentally during upper digestive endoscopies,presenting as simple gastric *** cases(type I and type II)are related to hypergastrinemia,can be multiple and are treated by endoscopic resection,whenever *** use of somatostatin analogs for tumor control may be one of the options for therapy,in addition to total or subtotal gastrectomy for selected *** chemotherapy is only reserved for poorly differentiated neuroendocrine *** rare,gastric neuroendocrine tumors have an increasing incidence over the years,therefore deserving more comprehensive studies on its adequate *** present study reviews and updates management recommendations for gastric neuroendocrine tumors.

关键词： Gastric neuroendocrine tumor Gastroenteropancreatic tumor Hypergastrinemia Gastric carcinoid Endoscopic resection

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Late onset acute Vogt-Koyanagi-Harada syndromechallenges on the way

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International Journal of Ophthalmology(English edition) 2018年第3期11卷 524-527页

作者： Sandra rodrigues-Barros Jacqueline Martins Sousa Bruno Carvalho gabriel Andrade Heloisa Nascimento Department of Ophthalmology Hospital Garcia de Orta Avenida Torrado da Silva Almada 2801-951 Portugal Department of Ophthalmology and Visual Sciences Escola Paulista de Medicina Universidade Federal de Sao Paulo Rua Botucatu 821 Vila Clementino Sao Paulo SP 04023-062 Brazil Department of Ophthalmology Centro Hospitalar de Lisboa Central Alameda Santo Antonio dos Capuchos Lisboa 1169- 050 Portugal

Dear Editor,We would like to share some clinical cases of late onset acute Vogt-Koyanagi-Harada syndrome （VKH）, a rare diagnosis in this age range.

关键词： Late onset acute Vogt-Koyanagi-Harada syndromechallenges the way

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Bone marrow-derived products: A classification proposal – bone marrow aspirate, bone marrow aspirate concentrate or hybrid?

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World Journal of Stem Cells 2020年第4期12卷 241-250页

作者： Joseph Purita JoséFábio Santos Duarte Lana Morey Kolber Bruno Lima rodrigues Tomas Mosaner gabriel Silva Santos Carolina Caliari-Oliveira Stephany Cares Huber Institute of Regenerative Medicine Boca RatonFL 33432United States Institute of Bone and Cartilage IndaiatubaSP 13334-170Brazil Department of Physical Therapy Nova Southeastern UniversityFort LauderdaleFL 33314United States University of Campinas CampinasSP 13083-970Brazil In Situ Cell Therapy Ribeirao PretoSP 14056-680Brazil

Degenerative musculoskeletal disorders are one of the top causes of pain and disability in the adult *** available alternatives to mitigate symptoms include conservative treatments such as the administration of pharmacological agents and an educative approach towards lifestyle *** use of certain analgesics,such as opiates and corticosteroids,delivers short term results but do not address the etiological source of pain and ***,prolonged use of such medications may cause additional ***,the demand for musculoskeletal tissue regeneration has led to an alternative approach referred to as“orthobiologics”.This alternative is based on cellular and molecular components capable of inducing and promoting tissue *** marrow(BM)aspirate(BMA)and concentrate are well-known orthobiologics used to treat musculoskeletal *** derived from the BM have been discussed in the literature;however,the lack of standardization regarding collection and processing protocols presents a challenge for generalization of study outcomes and determination of *** BM-derived orthobiologics have not yet been classified,to our knowledge,this manuscript proposes the ACH classification system,which speaks to BMA(A),BMA and concentrate(C)and hybrid(H),which combines A and *** classification proposes and describes 8 parameters that are relevant for the quality of biological *** more parameters used would imply greater characterization and complexity of the evaluation of the biological product *** ACH classification envisages a necessary contribution to the comprehension of both clinical procedures and research outcomes,ultimately ushering in a standardization of best practice.

关键词： Bone-marrow classification Bone-marrow aspirate concentrate Regenerativemedicine Stem cells Musculoskeletal disorders Orthobiologics

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Who Am I on Facebook？ Usage and Motivation Through User Eyes

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Psychology Research 2014年第1期4卷 60-73页

作者： gabriel Artur Marra e Rosa, Benedito rodrigues dos Santos Catholic University of Brasilia Brasilia-DF Brazil

This article discusses different modes of using Facebook and the motivation for its users. The analysis aims to clarify how and why users might resort to one or more usage modes when joining this social network and emphasizes the relationship between interactions mediated by this social network and user identity. For this we conducted semi-structured interviews with 10 young Facebook users-five males and five females-all residing in Brasilia-DF, Brazil. The results obtained were compared with those found in previous research. We used theoretical derived data from social psychology and socio-cultural anthropology for the data analysis and conducted an accurate literature review. The conclusion goes beyond the distinction between motivation and usage and expresses a critical analysis of Facebook usage purposes thus indicating widespread use that can extend to other specifics depending on the interests of the participants. Furthermore, there is motivation behind Facebook which is not yet mentioned in existing research which attracts enthusiasts to Facebook and is directly related to the issue of identity in the contemporary world.

关键词：用户模式眼睛员工激励用法社会网络巴西利亚文化人类学

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The role of environmental temperature on movement patterns of giant anteaters

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Integrative Zoology 2022年第2期17卷 285-296页

作者： Aline GIROUX Zaida ORTEGA Alessandra BERTASSONI Arnaud Léonard Jean DESBIEZ Danilo KLUYBER gabriel Favero MASSOCATO Guilherme DE MIRANDA Guilherme MOURÃO Luciana SURITA Nina ATTIAS Rita de Cassia BIANCHI Vinícius Peron de Oliveira GASPAROTTO Luiz Gustavo rodrigues OLIVEIRA-SANTOS Ecology Department Federal University of Mato Grosso do Sul(UFMS)Campo GrandeMato Grosso do SulBrazil Post Graduate Program of Ecology and Evolution Federal University of Goiás(UFG)GoiâniaGoiásBrazil Institute of Research and Conservation of Anteaters in Brazil(PROJETO TAMANDUÁ) ParnaíbaPiauíBrazil Institute for the Conservation of Wild Animals(ICAS) Campo GrandeMato Grosso do SulBrazil Royal Zoological Society of Scotland(RZSS) MurrayfieldEdinburghUK Institute for Ecological Research(IPÊ) NazaréPaulistaSão PauloBrazil Naples Zoo at Caribbean Gardens NaplesFloridaUSA The Houston Zoo HoustonTexasUSA National Institute of Criminalistics-Federal Police BrasíliaBrazil Embrapa Pantanal CorumbáMato Grosso do SulBrazil Natural Resources Graduate Program(PRONAT)-Federal University of Roraima(UFRR) Boa VistaRoraimaBrazil Animal Biology Graduate Program Federal University of Mato Grosso do Sul(UFMS)Campo GrandeMato Grosso do SulBrazil Animal Biology Department São Paulo State University(UNESP)São Josédo Rio PretoSão PauloBrazil Department of Preventive Veterinary Medicine and Animal Health School of Veterinary MedicineUniversity of São Paulo(USP)São PauloSPBrazil Brazilian Institute for Conservation Medicine(TRÍADE) RecifePernambucoBrazil

Mammals can show conspicuous behavioral responses to thermal variation,including changes in movement *** used an integrative approach to understand how environmental temperature can drive the movement behavior of a mammal with low capacity for physiological thermoregulation,the giant anteater(Myrmecophaga tridactyla).We tracked 52 giant anteaters in 7 areas throughout the Brazilian *** estimated the distance moved,area used,use of forest areas,and mean environmental temperature for each monitoring day of each *** modeled these data with Mixed Structural Equations—considering the possible interactions between our variables and controlling for sex and body *** anteaters reduced displacement and increased forest use with decreasing environmental temperature,probably because of their low body heat *** is possible that they reduce distance moved and area used by reducing the duration of *** decreasing temperature,forest habitats become warmer than open ones,besides buffer rain and chilly *** displacement and using forests are important strategies to reduce body heat loss and the energetic costs of ***,decreasing movement can limit food access and,consequently,***,we highlight the importance of forests as thermal *** increasing frequency and intensity of extreme weather events,we showed the need to preserve forest patches to offer suitable conditions for tropical mammals’behavioral *** this context,policies favoring deforestation on Brazilian territory are especially ***,we emphasize the need of integrative approaches to understand the complex interactions between organisms and the environment.

关键词： behavioral thermoregulation biologging habitat use mixed structural equations movement ecology

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Reaching the malaria elimination goal in Brazil:a spatial analysis and time-series study

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Infectious Diseases of Poverty 2022年第2期11卷 104-104页

作者： gabriel Zorello Laporta Maria Eugenia Grillet Sheila rodrigues Rodovalho Eduardo Massad Maria Anice Mureb Sallum Graduate Research and Innovation Program Centro Universitario FMABCSanto AndreSPBrazil 不详 Epidemiology Department School of Public HealthUniversity of Sao PauloSão PauloSPBrazil

Background:Since 2015,the Global Technical Strategy(GTS)for Malaria 2016–2030 has been adopted by the World Health Organization(WHO)as a comprehensive framework to accelerate progress for malaria elimination in endemic *** strategy sets the target of reducing global malaria incidence and mortality rates by 90% in *** it is sought to evaluate Brazil’s achievements towards reaching the WHO GTS milestone in *** the total number of new malaria cases in 2015,the main research question is:will Brazil reach the malaria elimination goal in 2030?Methods:Analytical strategies were undertaken using the SIVEP-malaria ofcial databases of the Brazilian Malaria Control Programme for the Brazilian Amazon region from 2009 to *** and time-series analyses were applied for identifying municipalities that support the highest numbers of malaria cases over the *** analysis was used for predicting the estimated number of new cases in Brazil in 2025–***:Brazil has signifcantly reduced the number of new malaria cases in 2020 in comparison with 2015 in the states of Acre(−56%),Amapá(−75%),and Amazonas(−21%);however,they increased in the states of Pará(156%),Rondônia(74%),and Roraima(362%).Forecast of the predicted number of new malaria cases in 2030 is 74,764(95%CI:41,116–141,160)in the Brazilian ***:It is likely that Brazil will reduce the number of new malaria cases in the Brazilian Amazon in 2030 in relation to that in *** forecast shows a reduction by 46%(74,754 in 2030 forecast/137,982 in 2015),but this reduction is yet far from the proposed reduction under the WHO GTS 2030 milestone(90%).Stable and unbeatable transmission in the Juruá River Valley,Manaus,and Lábrea still support endemic malaria in the Brazilian ***’s cross-border malaria is impacting the state of Roraima *** this situation is maintained,the malaria elimination goal(zero cases)may not be reached before *** enhanced

关键词： Malaria Antimalarials therapeutic use Brazil Eradication Prevention and control Policy

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Acute kidney injury and electrolyte disorders in COVID-19

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World Journal of Virology 2022年第5期11卷 283-292页

作者： gabriel Martins Nogueira Noel Lucas Oliveira rodrigues Silva Ana Flávia Moura Marcelo Augusto Duarte Silveira JoséA Moura-Neto Department of Medicine Bahiana School of Medicine and Public HealthSalvador 40290-000BahiaBrazil Department of Nephrology D’Or Institute for Research and EducationHospital São RafaelSalvador 41253900BahiaBrazil

Acute kidney injury(AKI)and electrolyte disorders are important complications of hospitalized coronavirus disease 2019(COVID-19)*** is thought to occur due to multiple pathophysiological mechanisms,such as multiple organ dysfunction(mainly cardiac and respiratory),direct viral entry in the renal tubules,and cytokine release *** is present in approximately one in every ten hospitalized COVID-19 *** incidence rates of AKI increase in patients who are admitted to the intensive care unit(ICU),with levels higher than 50%.Additionally,renal replacement therapy(RRT)is used in 7%of all AKI cases,but in nearly 20%of patients admitted to an ***-19 patients with AKI are considered moderate-to-severe cases and are managed with multiple interdisciplinary *** acts as a risk factor for mortality in severe acute respiratory syndrome coronavirus 2 infection,especially when RRT is *** disorders are also common manifestations in hospitalized COVID-19 patients,mainly hyponatremia,hypokalemia,and *** occurs due to a combination of syndrome of inappropriate secretion of antidiuretic hormone and gastrointestinal fluid loss from vomiting and *** it comes to hypokalemia,its mechanism is not fully understood but may derive from hyperaldosteronism due to renin angiotensin aldosterone system overstimulation and gastrointestinal fluid loss as *** clinical features of hypokalemia in COVID-19 are similar to those in other *** is the most common electrolyte disorder in COVID-19 and seems to occur because of vitamin D deficiency and parathyroid *** is also highly associated with longer hospital and ICU stay.

关键词： COVID-19 SARS-CoV-2 Acute kidney injury Electrolyte disorders Renal dialysis

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