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A facile strategy for tuning the density of surface-grafted biomolecules for melt extrusion-based additive manufacturing applications

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bio-Design and Manufacturing 2024年第3期7卷 277-291页

作者： I.A.O.beeren G.Dos Santos P.J.Dijkstra C.Mota J.bauer H.Ferreira Rui L.Reis N.Neves S.Camarero-espinosa M.b.baker L.Moroni Department of Complex Tissue Regeneration MERLN Institute for Technology-Inspired Regenerative MedicineMaastricht University6229 ER MaastrichtThe Netherlands 3b’s Research Group I3Bs–Research Institute on BiomaterialsBiodegradables and BiomimeticsHeadquarters of the European Institute of Excellence on Tissue Engineering and Regenerative MedicineUniversity of MinhoAveParkZona Industrial da Gandra4805-017 BarcoGuimarãesPortugal ICVS/3b’s-PT Government Associate Laboratory 4806-909 Braga/GuimarãesPortugal POLYMAT University of the Basque Country UPV/EHU20018 Donostia/San SebastiánSpain IKeRbASQUe Basque Foundation for Science48009 BilbaoSpain

Melt extrusion-based additive manufacturing(Me-AM)is a promising technique to fabricate porous scaffolds for tissue engi-neering ***,most synthetic semicrystalline polymers do not possess the intrinsic biological activity required to control cell *** of biomolecules on polymeric surfaces of AM scaffolds enhances the bioactivity of a construct;however,there are limited strategies available to control the surface ***,we report a strategy to tune the surface density of bioactive groups by blending a low molecular weight poly(ε-caprolactone)5k(PCL5k)containing orthogonally reactive azide groups with an unfunctionalized high molecular weight PCL75k at different *** porous three-dimensional(3D)scaf-folds were then fabricated using a high weight percentage(75 wt.%)of the low molecular weight PCL *** a proof-of-concept test,we prepared films of three different mass ratios of low and high molecular weight polymers with a thermopress and reacted with an alkynated fluorescent model compound on the surface,yielding a density of 201-561 pmol/cm^(2).Subsequently,a bone morphogenetic protein 2(bMP-2)-derived peptide was grafted onto the films comprising different blend compositions,and the effect of peptide surface density on the osteogenic differentiation of human mesenchymal stromal cells(hMSCs)was *** two weeks of culturing in a basic medium,cells expressed higher levels of bMP receptor II(bMPRII)on films with the conjugated *** addition,we found that alkaline phosphatase activity was only significantly enhanced on films contain-ing the highest peptide density(i.e.,561 pmol/cm^(2)),indicating the importance of the surface *** together,these results emphasize that the density of surface peptides on cell differentiation must be considered at the cell-material ***,we have presented a viable strategy for Me-AM community that desires to tune the bulk and surface functionality via blending of(m

关键词： Additive manufacturing blending Surface functionalization Surface density Click chemistry Human

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Profile of bionectriaceae,Calcarisporiaceae,Hypocreaceae,Nectriaceae,Tilachlidiaceae,Ijuhyaceae ***.,Stromatonectriaceae *** Xanthonectriaceae ***

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Fungal Diversity 2023年第1期118卷 95-271页

作者： R.H.Perera K.D.Hyde e.b.G.jones S.S.N.Maharachchikumbura D.bundhun e.Camporesi A.Akulov J.K.Liu Z.Y.Liu Guizhou Key Laboratory of Agricultural biotechnology Guizhou Academy of Agricultural SciencesGuiyang 550006GuizhouPeople’s Republic of China Center of excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Mushroom Research Foundation 128 M.3 Ban Pa Deng T.Pa PaeA.Mae TaengChiang Mai 50150Thailand Key Laboratory for Plant Diversity and biogeography of east Asia Kunming Institute of BotanyChinese Academy of ScienceKunming 650201YunnanPeople’s Republic of China World Agroforestry Centre East and Central AsiaKunming 650201YunnanPeople’s Republic of China Innovative Institute of Plant Health Zhongkai University of Agriculture and EngineeringHaizhu DistrictGuangzhou 510225People’s Republic of China School of Life Science and Technology University of Electronic Science and Technology of ChinaChengdu 611731People’s Republic of China Department of entomology and Plant Pathology Faculty of AgricultureChiang Mai UniversityChiang Mai 50200Thailand Department of botany and Microbiology College of ScienceKingdom of Saudi ArabiaKing Saud UniversityP.O Box 2455Riyadh 11451Saudi Arabia A.M.b Circolo Micologico“Giovanni Carini”C.P.314BresciaItaly A.M.b.Gruppo Micologico Forlivese“Antonio Cicognani”Via Roma 18ForliItaly Societaper Gli Studi Naturalistici Della Romagna C.P.143BagnacavalloRAItaly Department of Mycology and Plant Resistance V.N.Karazin Kharkiv National UniversityMaidan Svobody 4Kharkiv 61022Ukraine

This paper provides outlines for bionectriaceae,Calcarisporiaceae,Hypocreaceae,Nectriaceae,Tilachlidiaceae,Ijuhy-aceae,Stromatonectriaceae and Xanthonectriaceae with taxonomic *** provide up-to-date DNA sequence-based phylogenies including combined gene analysis of ITS,LSU,rpb2,tef1 and tub2 for Hypocreales and accept 17 *** new families and 12 new species are introduced with descriptions and illustrations,while 13 new records and one new species combination are *** we mainly detail the taxonomy of bionectriaceae,Hypocreaceae,Nectriaceae and Tilachlidiaceae,Ijuhyaceae ***.,Stromatonectriaceae *** Xanthonectriaceae *** introduced in this study based on phenotypic and molecular *** each family we provide a list of accepted genera,the taxo-nomic history,morphological descriptions,taxonomic placement based on DNA sequence data and illustrate the type *** of each family are illustrated based on the type herbarium material or fresh specimens where available,or provide relevant *** on ecological and economic importance of the families are also given.

关键词： 15 New taxa Genera incertae sedis Hypocreales New records Outline Phylogeny Sordariomycetes Taxonomy

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Application of the Shrinking Particle Model for the evaluation of Molecular Recyclability of PeT versus Semi-Aromatic Polyesters

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Open Journal of Physical Chemistry 2024年第2期14卷 21-35页

作者： Jack van Schijndel Sanne de Krom Dennis Molendijk Koen van beurden Amarante böttger Research Group biopolymers/Green Chemistry Centre of Expertise Safe & Resilient Society Avans University of Applied Science Breda Netherlands New Materials and Their Applications Centre of Expertise Safe & Resilient Society Avans University of Applied Science Breda Netherlands Department of Materials Science and engineering Delft University of Technology Delft Netherlands

The molecular recyclability of poly (ethylene terephthalate) (PeT) and three semi-aromatic polyesters poly (phloretic acid) (poly-H), poly (dihydroferulic acid) (poly-G), and poly (dihydrosinapinic acid) (poly-S) is evaluated in this study. PeT is an extensively used aromatic polyester, and poly-H, poly-G, and poly-S can be considered semi-aromatic poly (lactic acid) modifications. All these polyesters have been depolymerized at neutral pH and by acid- and base-catalyzed hydrolysis at two temperatures, i.e., 50˚C and 80˚C. base-catalyzed depolymerization of virgin PeT leads to an isolated yield of 38% after 48 hours of reaction at 80˚C. Contrary to these results for PeT, almost all the monomers of the semi-aromatic polyesters poly-H, poly-G, and poly-S are recovered with isolated yields larger than 90% at the same temperature after 15 minutes in a facile manner. A shrinking particle model used to determine the global kinetics of the base-catalyzed depolymerization showed that the rate rises with increasing temperature. Using the shrinking particle model, the intrinsic reaction rate constants were determined. It has been demonstrated that the rate coefficients of the depolymerization of the semi-aromatic polyesters poly-H, poly-G, and poly-S are between 2 and 3 orders of magnitude higher than those for PeT.

关键词： Depolymerization Molecular Recycling Poly-H Poly-G Poly-S PeT Circular Polymers

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Philippine retinoblastoma initiative multi-eye center study 2010-2020

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International Journal of Ophthalmology(english edition) 2024年第1期17卷 144-156页

作者： Roland Joseph D.Tan gary John V.Mercado Patricia e.Cabrera Paulita Pamela P.Astudillo Rolando enrique D.Domingo Josept Mari S.Poblete Charmaine Grace M.Cabebe Adriel Vincent R.Te Melissa Anne S.Gonzales Jocelyn G.Sy beltran Alexis A.Aclan Jayson T.So Fatima G.Regala Kimberley Amanda K.Comia Josemaria M.Castro Mara Augustine S.galang Aldous Dominic C.Cabanlas benedicto Juan e.Aguilar gabrielle S.evangelista Jo Michael Maniwan Andrei P.Martin Calvin Y.Martinez John Alfred H.Lim Rena Ivy bascuna Rachel M.Ng Kevin b.Agsaoay Kris Zanna A.Acluba-Arao ellaine Rose V.Apostol beatriz M.Prieto Department of Ophthalmology and Visual Sciences Philippine General HospitalManila 1000Philippines Department of Ophthalmology Baguio General Hospital and Medical CenterBaguio City 2600Philippines Department of Ophthalmology Manila Doctors HospitalManila 1000Philippines Department of Ophthalmology Rizal Medical CenterPasig City 1600Philippines Department of Ophthalmology Jose B.Lingad Memorial Regional HospitalPampanga 2000Philippines Department of Ophthalmology Southern Philippines Medical CenterDavao City 8000Philippines Department of Ophthalmology East Avenue Medical CenterQuezon City 1100Philippines Department of Ophthalmology Northern Mindanao Medical CenterCagayan de Oro City 9000Philippines Department of Ophthalmology Cebu Velez General HospitalCebu City 6000Philippines Legazpi eye Center Legazpi City 4500Philippines Department of Ophthalmology Cagayan Valley Medical CenterTuguegarao City 3500Philippines

AIM:To provide a comprehensive and more representative national data on the disease,especially on treatment options and outcomes,and to determine access of retinoblastoma patients from Luzon,Visayas and Mindanao to eye care,and determine if access is associated with delay in consultation,staging and ***:Cohort study of retinoblastoma patients seen in eleven institutions located in the three major areas of the Philippines namely Luzon,Vizayas and Mindanao from ***:Totally 636 patients,involving 821 eyes,were ***(57%)were from Luzon and were seen in institutions in Luzon(72%).Annually,58±10 new cases were seen with 71%having unilateral *** delay of consultation remained long at 9(3,17)mo,longest in patients with unilateral disease(Pe from the Visayas(Pbased on the International Retinoblastoma Staging System,only 35%of patients had Stage 1 while 47%already had extraocular *** was the most common treatment received by 484 patients while intravenous chemotherapy was received by *** were 250(39%)patients alive,195(31%)dead,85(13%)abandoned,17(3%)refused and 89(14%)with no ***:This study presents the largest cohort of retinoblastoma patients in the Philippines in terms of patients’and participating institutions’number and geographical location and type of institution(private and public).It also presents more comprehensive data on the treatments used and outcomes(survival,globe salvage,and vision retention rates).Delay in consultation was still long among patients leading to advanced disease stage and lower survival *** increasing capacity to diagnose and manage retinoblastoma in the country,the delay of consultation remains long primarily due to accessibility issues to eye care institutions especially in the Visayas and financial *** delay was still significant that overall survival rate remain low.

关键词： retinoblastoma Philippines clinical profile

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STCF conceptual design report (Volume 1): Physics & detector

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Frontiers of physics 2024年第1期19卷 1-154页

作者： M.Achasov X.C.Ai L.P.An R.Aliberti Q.An X.Z.bai Y.bai O.bakina A.barnyakov V.blinov V.bobrovnikov D.bodrov A.bogomyagkov A.bondar I.boyko Z.H.bu F.M.Cai H.Cai J.J.Cao Q.H.Cao X.Cao Z.Cao Q.Chang K.T.Chao D.Y.Chen H.Chen H.X.Chen J.F.Chen K.Chen L.L.Chen P.Chen S.L.Chen S.M.Chen S.Chen S.P.Chen W.Chen X.Chen X.F.Chen X.R.Chen Y.Chen Y.Q.Chen H.Y.Cheng J.Cheng S.Cheng T.G.Cheng J.P.Dai L.Y.Dai X.C.Dai D.Dedovich A.Denig I.Denisenko J.M.Dias D.Z.Ding L.Y.Dong W.H.Dong V.Druzhinin D.S.Du Y.J.Du Z.G.Du L.M.Duan D.epifanov Y.L.Fan S.S.Fang Z.J.Fang G.Fedotovich C.Q.Feng X.Feng Y.T.Feng J.L.Fu J.gao Y.N.gao P.S.Ge C.Q.Geng L.S.Geng A.Gilman L.Gong T.Gong b.Gou W.Gradl J.L.Gu A.Guevara L.C.Gui A.Q.Guo F.K.Guo J.C.Guo J.Guo Y.P.Guo Z.H.Guo A.Guskov K.L.Han L.Han M.Han X.Q.Hao J.b.He S.Q.He X.G.He Y.L.He Z.b.He Z.X.Heng b.L.Hou T.J.Hou Y.R.Hou C.Y.Hu H.M.Hu K.Hu R.J.Hu W.H.Hu X.H.Hu Y.C.Hu J.Hua G.S.Huang J.S.Huang M.Huang Q.Y.Huang W.Q.Huang X.T.Huang X.J.Huang Y.b.Huang Y.S.Huang N.Hüsken V.Ivanov Q.P.Ji J.J.Jia S.Jia Z.K.Jia H.b.Jiang J.Jiang S.Z.Jiang J.b.Jiao Z.Jiao H.J.Jing X.L.Kang X.S.Kang b.C.Ke M.Kenzie A.Khoukaz I.Koop e.Kravchenko A.Kuzmin Y.Lei e.Levichev C.H.Li C.Li D.Y.Li F.Li G.Li G.Li H.b.Li H.Li H.N.Li H.J.Li H.L.Li J.M.Li J.Li L.Li L.Li L.Y.Li N.Li P.R.Li R.H.Li S.Li T.Li W.J.Li X.Li X.H.Li X.Q.Li X.H.Li Y.Li Y.Y.Li Z.J.Li H.Liang J.H.Liang Y.T.Liang G.R.Liao L.Z.Liao Y.Liao C.X.Lin D.X.Lin X.S.Lin b.J.Liu C.W.Liu D.Liu F.Liu G.M.Liu H.b.Liu J.Liu J.J.Liu J.b.Liu K.Liu K.Y.Liu K.Liu L.Liu Q.Liu S.b.Liu T.Liu X.Liu Y.W.Liu Y.Liu Y.L.Liu Z.Q.Liu Z.Y.Liu Z.W.Liu I.Logashenko Y.Long C.G.Lu J.X.Lu N.Lu Q.F.Lü Y.Lu Y.Lu Z.Lu P.Lukin F.J.Luo T.Luo X.F.Luo Y.H.Luo H.J.Lyu X.R.Lyu J.P.Ma P.Ma Y.Ma Y.M.Ma F.Maas S.Malde D.Matvienko Z.X.Meng R.Mitchell A.Nefediev Y.Nefedov S.L.Olsen Q.Ouyang P.Pakhlov G.Pakhlova X.Pan Y.Pan e.Passemar Y.P.Pei H.P.Peng L.Peng X.Y.Peng X.J.Peng K.Peters S.Pivovarov e.Pyata b.b.Qi Y.Q.Qi W.b.Qian Y.Qian C.F.Qiao J.J.Qin J.J.Qin L.Q.Qin X.S.Qin T.L.Qiu J.Rademacker C.F.Redmer H.Y.Sang Anhui University Hefei 230039China beihang University Beijing 100191China budker Institute of Nuclear Physics Novosibirsk 630090Russia CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China Cavendish Laboratory University of CambridgeJJ Thomson AveCambridge CB30HEUnited Kingdom Central China Normal University Wuhan 430079China Central South University Changsha 410083China China University of Geosciences Wuhan 430074China China University of Mining and Technology Xuzhou 221116China École Polytechnique Fédérale de Lausanne(ePFL) LausanneSwitzerland Fudan University Shanghai 200433China Goethe University Frankfurt D-60325 Frankfurt am MainGermany Guangxi Normal University Guilin 541004China Guangxi Uninversity Nanning 530004China Hangzhou Institute for Advanced Study UCASHangzhou 310024China Hebei Normal University Shijiazhuang 050024China Hebei University Baoding 071002China Hefei University of Technology Hefei 230601China Helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University Kaifeng 475004China High energy Physics Center Chung-Ang UniversitySeoul 06974Korea Higher School of economy 11 Pokrovsky bulvar Moscow 109028Russia Huangshan University Huangshan 245000China Hubei University of Automotive Technology Shiyan 442002China Hunan Normal University Changsha 410081China Hunan University of Science and Technology Xiangtan 411201China Hunan University Changsha 410082China Indiana University BloomingtonIndiana 47405USA Inner Mongolia University Hohhot 010021China Institute of Advanced Science Facilities Shenzhen 518107China Institute of High energy Physics Chinese Academy of SciencesBeijing 100049China Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China Institute of Physics Academia SinicaTaipeiTaiwan 11529China Institute of Theoretical Physics Chinese Academy of SciencesBeijing 100190China Jilin University Changch

The superτ-charm facility(STCF)is an electron–positron collider proposed by the Chinese particle physics *** is designed to operate in a center-of-mass energy range from 2 to 7 GeV with a peak luminosity of 0.5×10^(35) cm^(–2)·s^(–1) or *** STCF will produce a data sample about a factor of 100 larger than that of the presentτ-charm factory—the bePCII,providing a unique platform for exploring the asymmetry of matter-antimatter(charge-parity violation),in-depth studies of the internal structure of hadrons and the nature of non-perturbative strong interactions,as well as searching for exotic hadrons and physics beyond the Standard *** STCF project in China is under development with an extensive R&D *** document presents the physics opportunities at the STCF,describes conceptual designs of the STCF detector system,and discusses future plans for detector R&D and physics case studies.

关键词： electron–positron collider tau-charm region high luminosity STCF detector conceptual design

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A New Cytotoxic Sterol Produced by an endophytic Fungus from Castaniopsis fissa at the South China Sea Coast

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Chinese Chemical Letters 2004年第4期15卷 419-422页

作者： HouJinLI YongChengLIN L.L.P.VRIJMOeD e.b.G.jones DepartmentofAppliedChemistry ZhongshanUniversityGuangzhou510275 DepartmentofbiologyandChemistry CityUniversityofHongKongHongKong

A new sterol, ergosta-8(9),22-diene-3,5,6,7-tetraol(3β,5α,6β,7α,22e)(A) together with three known sterols: 3β, 5α,6β-trihydroxyergosta-7,22-diene (b), 3β-hydroxy-5α,8α- epidioxyer-gosta-6,22-diene (C) and ergosterol (D) were isolated from the mycelia of an unidentified endophytic fungus separated from Castaniopsis fissa (chestnut tree). Compound A exhibited potent selective cytotoxicity against bel-7402, NCI4460 and L-02 cell lines with IC50 values 8.445, 5.03, 13.621 μg/mL, respectively.

关键词： endophytic fungus sterols ergosta-8(9) 22-diene-3,5,6,7-tetraol (3β,5α,6β,7α,22e) cytotoxicity.

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Toxicity of a seafood toxin， domoic acid， in the retina via modulation of the NRF2 and NF-κb pathways

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Food Science and Human Wellness 2024年

作者： gabriel Mbuta Tchivelekete Yanqun Cao Mohammad Almarhoun Xinzhi Zhou Agostinho Francisco Cachapa Sebasti?o Tumitangua James Reilly Patricia e.Martin Xinhua Shu Department of biological and biomedical Sciences Glasgow Caledonian University Department of Marine biology Faculty of Natural Science University of Namibe Puai Medical School Shaoyang University Department of Vision Science Glasgow Caledonian University

Domoic acid (DA)， a biotoxin， is produced by several species of marine dinoflagellate and diatom during harmful algal bloom events. DA is a neurotoxin， in humans and non-human primates， oral exposure to DA results in gastrointestinal effects， while DA at higher doses leads to neurological symptoms， seizures and memory deficiency. exposure of humans to DA occurs mainly through consumption of contaminated seafoods containing an accumulation of the toxin. Previously， it was unclear if DA can have toxic effects on the retina. We assessed the toxicity of DA in human retinal cells (ARPe-19) and in zebrafish embryos. DA significantly lowered ARPe-19 cell viability dose-dependently， and decreased anti-oxidative capacity， increased inflammation， and promoted cell death， possibly through modulating the NRF2 and NF-κb signalling pathways. Zebrafish embryos exposed to DA for four days from one day post fertilization (dpf) had an increase in mortality and a decrease in both hatching and heartbeat rate and exhibited morphological abnormalities. DA treatment also significantly downregulated expression of antioxidant genes and upregulated expression of inflammation mediators， as well as causing photoreceptor death in zebrafish embryos. The results demonstrate that consuming seafood containing DA will have potential toxic effects in human retinas.

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Taxonomy,phylogeny,molecular dating and ancestral state reconstruction of Xylariomycetidae(Sordariomycetes)

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Fungal Diversity 2022年第1期112卷 1-88页

作者： Milan C.Samarakoon Kevin D.Hyde Sajeewa S.N.Maharachchikumbura Marc Stadler e.b.ga.eth jones Itthayakorn Promputtha Nakarin Suwannarach erio Camporesi Timur S.bulgakov Jian-Kui Liu School of Life Science and Technology Center for Informational BiologyUniversity of Electronic Science and Technology of ChinaChengdu 611731People’s Republic of China Research Center in bioresources for Agriculture Industry and MedicineChiang Mai UniversityChiang Mai 50200Thailand Department of biology Faculty of ScienceChiang Mai UniversityChiang Mai 50200Thailand Center of excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand Mushroom Research Foundation 128 M.3 Ban Pa Deng T.Pa PaeA.Mae TaengChiang Mai 50150Thailand Institute of Microbiology Technische Universität BraunschweigSpielmannstraße 738106 BrunswickGermany Department of botany and Microbiology College of ScienceKing Saud UniversityP.O Box 2455Riyadh 11451Kingdom of Saudi Arabia Research Center of Microbial Diversity and Sustainable Utilization Chiang Mai UniversityChiang Mai 50200Thailand A.M.b.Gruppo Micologico Forlivese"Antonio Cicognani"Via Roma 18ForliItaly Department of Plant Protection Federal Research Centre the Subtropical Scientific Centre of the Russian Academy of SciencesYana Fabritsiusa Street 2/28SochiKrasnodar RegionRussia 354002

Xylariomycetidae(Ascomycota)is a highly diversified group with variable stromatic *** research focused on inconspicuous stromatic xylarialean taxa from China,Italy,Russia,Thailand and the United *** morpho-logical descriptions,illustrations and combined ITS-LSU-rpb2-tub2-tef1 phylogenies revealed 39 taxa from our collections belonging to Amphisphaeriales and Xylariales.A new family(Appendicosporaceae),five new genera(Magnostiolata,Mela-nostictus,Neoamphisphaeria,Nigropunctata and Paravamsapriya),27 new species(Acrocordiella photiniicola,Allocryp-tovalsa sichuanensis,Amphisphaeria parvispora,Anthostomella lamiacearum,Apiospora guiyangensis,***,biscogniauxia magna,eutypa camelliae,Helicogermslita clypeata,Hypocopra zeae,Magnostiolata mucida,Melanostictus longiostiolatus,***,Nemania longipedicellata,***,***,***,Neoamphispha-eria hyalinospora,Neoanthostomella bambusicola,Nigropunctata bambusicola,***,***,Occul-titheca rosae,Paravamsapriya ostiolata,Peroneutypa leucaenae,Seiridium italicum and Vamsapriya mucosa)and seven new host/geographical records are introduced and *** time estimates indicate that Delonicicolales diverged from Amphisphaeriales+Xylariales at 161(123-197)*** and Xylariales diverged 154(117-190)MYA with a crown age of 127(92-165)MYA and 147(111-184)MYA,***(Amphisphaeriales)has a stem age of 89(65-117)*** character state reconstruction indicates that astromatic,clypeate ascomata with aseptate,hyaline ascospores that lack germ slits may probably be ancestral Xylariomycetidae having plant-fungal endo-phytic *** Amphisphaeriales remained mostly astromatic with common septate,hyaline *** variations may have developed mostly during the Cretaceous *** ascospores are common in Xylariales,but they first appeared in Amphisphaeriaceae,Melogrammataceae and Sp

关键词： 33 new taxa Amphisphaeriales Appendicosporaceae evolution Stromata Xylariales

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Recent Ventures in Interdisciplinary Arctic Research:The ARCPATH Project

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Advances in Atmospheric Sciences 2024年第8期41卷 1559-1568页

作者： Astrid e.J.OGILVIe Leslie A.KING Noel KeeNLYSIDe François COUNILLON brynhildur DAVIÐSDÓTTIR Níels eINARSSON Sergey GULeV Ke FAN Torben KOeNIGK James R.MCGOODWIN Marianne H.RASMUSSON Shuting YANG Institute of Arctic and Alpine Research(INSTAAR) University of ColoradoBoulder CO 80303USA Stefansson Arctic Institute AkureyriÍS-600Iceland Royal Roads University BC V9B 5Y2Canada University of bergen Bergen N-5007Norway Nansen environmental and Remote Sensing Centre Bergen N-5007Norway University of Iceland Reykjavík 102Iceland Shirshov Institute of Oceanology Moscow 117218Russia Moscow State University Moscow 11991Russia Chinese Academy of Sciences Beijing 100045China Swedish Meteorological and Hydrological Institute SE-60176 NorrköpingSweden Danish Meteorological Institute CopenhagenØ2100Denmark Obukhov Institute of Atmospheric Physics RAS119017MoscowRussia

This paper celebrates Professor Yongqi gaO's significant achievement in the field of interdisciplinary studies within the context of his final research project Arctic Climate Predictions: Pathways to Resilient Sustainable Societies-ARCPATH(https://***/en/projects/finished-projects/arcpath). The disciplines represented in the project are related to climatology, anthropology, marine biology, economics, and the broad spectrum of social-ecological studies. Team members were drawn from the Nordic countries, Russia, China, the United States, and Canada. The project was transdisciplinary as well as interdisciplinary as it included collaboration with local knowledge holders. ARCPATH made significant contributions to Arctic research through an improved understanding of the mechanisms that drive climate variability in the Arctic. In tandem with this research, a combination of historical investigations and social, economic, and marine biological fieldwork was carried out for the project study areas of Iceland, Greenland, Norway, and the surrounding seas, with a focus on the joint use of ocean and sea-ice data as well as social-ecological drivers. ARCPATH was able to provide an improved framework for predicting the near-term variation of Arctic climate on spatial scales relevant to society, as well as evaluating possible related changes in socioeconomic realms. In summary, through the integration of information from several different disciplines and research approaches, ARCPATH served to create new and valuable knowledge on crucial issues, thus providing new pathways to action for Arctic communities.

关键词： Recent Ventures in Interdisciplinary Arctic Research:The ARCPATH Project

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治疗后早期MRI预测肝细胞癌放射性肝段切除术后的长期反应

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国际医学放射学杂志 2024年第2期 250-251页

作者： D.Stocker M.J.King M.e.Homsi J.Gnerre b.Marinelli M.Wurnig 朱婉秋

摘要目的应用钇-90放射性肝段切除术治疗早期肝细胞癌（HCC）具有重要意义，然而治疗后MRI对疗效评估的价值尚不明确。旨在评估放射性肝段切除术后早期MRI疗

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