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Antioxidative phytoceuticals to ameliorate pancreatitis in animal models: An answer from nature

World Journal of Gastroenterology 2014年第44期20卷 16570-16581页

作者： Jong-Min Park Sooyeon Lee Mi Kyung Chung Sung-hun Kwon Eun-Hee kim Kwang Hyun Ko Chang Il Kwon Ki Baik Hahm CHA Cancer Prevention Research Center CHA University Digestive Disease Center CHA University Bundang Medical Center

Despite enthusiastic efforts directed at elucidating critical underlying mechanisms towards the identification of novel therapeutic targets for severe acute pancreatitis(SAP), the disease remains without a specific therapy to be executed within the first hours to days after onset of symptoms. Although earlier management for SAP should aim to either treat organ failure or reduce infectious complications, the current standard of care for the general management of AP in the first hours to days after onset of symptoms include intravenous fluid replacement, nutritional changes, and the use of analgesics with a close monitoring of vital signs. Furthermore, repeated evaluation of severity is very important, as the condition is particularly unstable in the early stages. In cases where biliary pancreatitis is accompanied by acute cholangitis or in cases where biliary stasis is suspected,an early endoscopic retrograde cholangiopancreatography is ***,practice guidelines regarding the treatment of pancreatitis are *** chronic pancreatitis,conservative management strategies include lifestyle modifications and dietary changes followed by analgesics and pancreatic enzyme ***,attention has been focused on phytoceuticals or antioxidants as agents that could surpass the limitations associated with currently available *** oxidative stress has been shown to play an important role in the pathogenesis of pancreatitis,antioxidants alone or combined with conventional therapy may improve oxidativestress-induced organ *** in phytoceuticals stems from their potential use as simple,accurate tools for pancreatitis prognostication that could replace older and more tedious ***,the use of antioxidative nutrition or phytoceuticals may represent a new direction for clinical research in *** this review article,recent advances in the understanding of the pathogenesis of pancreatitis are discussed and the

关键词： Acute pancreatitis Chronic pancreatitis Se-vere ac

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水热还原制备镍包人造金刚石

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粉末冶金技术 2005年第6期23卷 418-422页

作者：梁焕珍黎少华张洁金东镇郑宪生中国科学院过程工程研究所北京100080 中国地质大学材料科学与工程学院北京100083 韩国地质科学与矿物资源研究院

采用水热加氢还原法制备了镍包金刚石(Ni/Dia.)复合粉末。制备过程包括预处理和包覆两个阶段。对表面活化剂氯化钯(PdCl2)的用量、溶液的组分、操作温度、氢分压以及搅拌速度等因素对反应过程和涂层质量的影响进行了详细的研究。结果表... 详细信息

采用水热加氢还原法制备了镍包金刚石(Ni/Dia.)复合粉末。制备过程包括预处理和包覆两个阶段。对表面活化剂氯化钯(PdCl2)的用量、溶液的组分、操作温度、氢分压以及搅拌速度等因素对反应过程和涂层质量的影响进行了详细的研究。结果表明,表面活化剂PdCl2是获得良好镍包覆层的关键。水热还原的最佳条件是:NH3/Ni摩尔比为2.4/1,氢分压为2.5MPa,温度165℃和搅拌速度为800r/min。

关键词：水热氢还原复合粉未镍包金刚石活化

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Multiple z-Score Based Method for Noninvasive Prenatal Test Using Cell-Free DNA in Maternal Plasma

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Open Journal of Genetics 2017年第1期7卷 1-8页

作者： Hyuk Jung Kwon Amit Goyal Heesu Im Kichan Lee Seon Young Yun Yoon Hee kim Sungjong Lee Mi-gyeong Lee Hyuna Lee Reena Garg Boram Park Soyoung Choi Joungsu Joo Jin-Sik Bae Min-Jeong kim Min Seob Lee Sunghoon Lee EONE-DIAGNOMICS Genome Center Co. Ltd. Inchon Korea

Objective: To improve the detecting accuracy of chromosomal aneuploidy of fetus by non-invasive prenatal testing (NIPT) using next generation sequencing data of pregnant women’s cell-free DNA. Methods: We proposed the multi-Z method which uses 21 z-scores for each autosomal chromosome to detect aneuploidy of the chromosome, while the conventional NIPT method uses only one z-score. To do this, mapped read numbers of a certain chromosome were normalized by those of the other 21 chromosomes. Average and standard deviation (SD), which are used for calculating z-score of each sample, were obtained with normalized values between all autosomal chromosomes of control samples. In this way, multiple z-scores can be calculated for 21 autosomal chromosomes except oneself. Results: Multi-Z method showed 100% sensitivity and specificity for 187 samples sequenced to 3 M reads while the conventional NIPT method showed 95.1% specificity. Similarly, for 216 samples sequenced to 1 M reads, Multi-Z method showed 100% sensitivity and 95.6% specificity and the conventional NIPT method showed a result of 75.1% specificity. Conclusion: Multi-Z method showed higher accuracy and robust results than the conventional method even at low coverage reads.

关键词： Cell-Free DNA z-Score Multiple Thresholds Coefficient of Variance Noninvasive Prenatal Testing NIPT

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韩国滑雪运动文化自觉实践与启示

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体育文化导刊 2021年第2期 17-22页

作者：刘敏金圣训王宁王健天津体育学院体育教育与教育科学学院天津301617 亚洲大学茶山学部韩国水原16499 南首尔大学生活体育学部韩国天安31000 天津体育学院社会体育与健康科学学院天津301617

采用文献资料法、比较分析法等,以文化自觉为视角,探讨韩国滑雪运动文化自觉的实践经验及对我国滑雪运动文化培育的启示。我国滑雪运动文化自觉的现实问题主要表现在滑雪运动文化发展的历史实践不能满足时代需求、文化主体面临多元体育... 详细信息

采用文献资料法、比较分析法等,以文化自觉为视角,探讨韩国滑雪运动文化自觉的实践经验及对我国滑雪运动文化培育的启示。我国滑雪运动文化自觉的现实问题主要表现在滑雪运动文化发展的历史实践不能满足时代需求、文化主体面临多元体育文化冲击、文化价值阐释尚待探索。韩国滑雪运动文化自觉的实践经验离不开历史自觉、主体自觉与价值自觉的联合推动,对我国的启示:以滑雪运动文化培育为基础前提,以滑雪运动文化规范为重要保障,以滑雪运动文化讲述为价值载体,以滑雪运动文化创新为路径选择。

关键词：冰雪运动滑雪运动文化文化自觉韩国

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国际组织的国际法律责任浅析

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山西高等学校社会科学学报 2009年第8期21卷 68-73页

作者：金大勋南京大学

伴随着国际组织的大量出现,国际组织的国际法律责任也成为一个日益重要的问题。国际组织承担国际法律责任的前提是需要具备独立的法律人格。而国际组织责任要件的构成则包括了客观要件和主观要件。分析国际组织的国际法律责任,有利于此... 详细信息

伴随着国际组织的大量出现,国际组织的国际法律责任也成为一个日益重要的问题。国际组织承担国际法律责任的前提是需要具备独立的法律人格。而国际组织责任要件的构成则包括了客观要件和主观要件。分析国际组织的国际法律责任,有利于此理论和实践的不断完善。

关键词：国际组织国际法律责任责任构成

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Efficacy in chickens of commercially inactivated Newcastle disease virus vaccines against recent Korean epizootic strain of NDV

Efficacy in chickens of commercially inactivated Newcastle d...

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The 15th World Veterinary Poultry Congress

作者： Woo-jin Jeon Eun-kyoung Lee Eun-im Yun Youn-jeong Lee Ok-mi Jeong Yong-joo kim Jun-hun Kwon Kang-seuk Choi National Veterinary Research ＆ Quarantine Service 480 Anyang-6AnyangGyeonggi 430-824Korea National Veterinary Research ＆ Quarantine Service 480 Anyang-6AnyangGyeonggi 430-824Korea National Veterinary Research ＆ Quarantine Service 480 Anyang-6AnyangGyeonggi 430-824Korea National Veterinary Research ＆ Quarantine Service 480 Anyang-6AnyangGyeonggi 430-824Korea National Veterinary Research ＆ Quarantine Service 480 Anyang-6AnyangGyeonggi 430-824Korea National Veterinary Research ＆ Quarantine Service 480 Anyang-6AnyangGyeonggi 430-824Korea National Veterinary Research ＆ Quarantine Service 480 Anyang-6AnyangGyeonggi 430-824Korea National Veterinary Research ＆ Quarantine Service 480 Anyang-6AnyangGyeonggi 430-824Korea

＜正＞Introduction Newcastle disease（ND）is one of the most disastrous diseases in the poultry *** Korea, extensive vaccination against ND has been implemented,but outbreaks have not stopped ***, there are at least e...

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Biochemical Characterization of Soluble Acid and Alkaline Invertases from Shoots of Etiolated Pea Seedlings

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Journal of Integrative Plant Biology 2010年第6期52卷 536-548页

作者： Donggiun kim So Yun Park Youngjae Chung Jongbum Park Sukchan Lee Taek-Kyun Lee Department of Biological Science Silla University South Sea Environment Research Department Korea Ocean Research and Development Institute Department of Life Science and Biotechnology Shin Gyeong University Department of Genetic Engineering Sungkyunkwan University

Soluble invertase was purified from pea （Pisum sativum L.） by sequential procedures entailing ammonium sulfate precipitation, DEAE-Sepharose column, Con-A- and Green 19-Sepharose affinity columns, hydroxyapatite column, ultra-filtration, and Sephacryl 300 gel filtration. The purified soluble acid （SAC） and alkaline （SALK） invertases had a pH optimum of 5.3 and 7.3, respectively. The temperature optimum of two invertases was 37 ℃. The effects of various concentrations of Tris-HCI, HgCI2, and CuSO4 on the activities of the two purified enzymes were examined. Tris-HCI and HgCI2 did not affect SAC activity, whereas 10 mM Tris-HCI and 0.05 mM HgCI2 inhibited SALK activity by about 50%. SAC and SALK were inhibited by 4.8 mM and 0.6 mM CuSO4 by 50%, respectively. The enzymes display typical hyperbolic saturation kinetics for sucrose hydrolysis. The Kms of SAC and SALK were determined to be 1.8 and 38.6 mM, respectively. The molecular masses of SAC shown by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and immunoblotting were 22 kDa and 45 kDa. The molecular mass of SALK was 30 kDa. Iso-electric points of the SAC and SALK were estimated to be about pH 7.0 and pH 5.7, respectively.

关键词： SAC Biochemical Characterization of Soluble Acid and Alkaline Invertases from Shoots of Etiolated Pea Seedlings

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种植体辅助的双丝弓技术矫治上颌异位阻生尖牙

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中国口腔医学继续教育杂志 2010年第1期13卷 8-16页

作者： Seong-hun kim HyeRan Choo Young-Sook Hwang Kyu-Rhim Chung 姜若萍（译）不详北京大学口腔医学院正畸科北京海淀区中关村南大街22号100081

本病例报告介绍一种新的双丝弓矫治技术，该技术借助正畸微种植体及微钛板，将一位14岁女．陛安氏Ⅲ类亚类错袷患者的双侧异位阻生上颌尖牙牵引到位。采取这种治疗方法的目的是为了保证侧切牙的健康和引导尖牙在正常解剖牙位萌出。作者... 详细信息

本病例报告介绍一种新的双丝弓矫治技术，该技术借助正畸微种植体及微钛板，将一位14岁女．陛安氏Ⅲ类亚类错袷患者的双侧异位阻生上颌尖牙牵引到位。采取这种治疗方法的目的是为了保证侧切牙的健康和引导尖牙在正常解剖牙位萌出。作者认为通过使用这种双丝弓技术可以尽可能减小正畸牵引过程中出现医源性牙根吸收的风险。

关键词：阻生尖牙矫治技术种植体上颌正畸牵引病例报告异位阻生安氏Ⅲ类

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Development of L-Type Fixation Equipment for Transporting Unit Modules

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Journal of Civil Engineering and Architecture 2015年第12期9卷 1423-1431页

作者： Kyoon-Tai kim Young-hun Jun Construction Policy Research Institute Korea Institute of Civil Engineering and Building Technology (KICT) Goyang-Si 10223 Gyeonggi-Do Korea

The unit modular technique is one in which unit modules are prefabricated in a factory and then constructed at a construction site. That is why an important process, transport of unit module, is added in this technique. However, it is not easy to transport a unit module that is high prefabrication ratio (prefab. ratio) (70~90%), since the walls and interior and exterior materials installed in it can become broken when the unit module is fixed using general fixation tools, including ropes and fixing belts. When the external wall, windows, etc. are damaged during the transportation, the efficiency of unit modular method is deteriorated. Taking this into account, the purpose of this study is to develop an improved fixation device that is convenient for fixing a unit module with a high prefab. ratio to a vehicle and securing the safety while running. The L-type adapter block proposed in this study was evaluated the structural safety through simulation method. The result of the simulation is that it seems desirable to set the working load of the L-type adapter block as 15 kN for Case 1 and 30 kN for Case 2. Therefore, when the L-type adapter block is utilized under the conditions in which the same load is applied as in Case 2, it is expected that safety will be improved.

关键词：单元模块固定装置模块型模块化技术输送现场施工运输过程模拟方法

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一株韩国新城疫近期流行株的分离——来自患有严重腹泻的发病猫头鹰体

一株韩国新城疫近期流行株的分离——来自患有严重腹泻的发病猫头...

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第15届世界禽病大会、中国畜牧兽医学会2007年学术年会

作者： Woo-Jin Jeon Eun-Kyoung Lee Jin-Ju Nah Young-Jun kim Mu-Yeong Lee Hang Lee Jun-hun Kwon Kang-Seuk Choi 施蕾刘爵 National Veterinary Research & Quarantine Service Ministry of Agriculture and Forestry Anyang Korea National Veterinary Research & Quarantine Service Ministry of Agriculture and Forestry Anyang Korea National Veterinary Research & Quarantine Service Ministry of Agriculture and Forestry Anyang Korea Conservation Genome Resource Bank for Korean Wildlife(CGRB) College of Veterinary Medicine and BK21 Program for Veterinary Science Seoul National University Seoul Korea Conservation Genome Resource Bank for Korean Wildlife(CGRB) College of Veterinary Medicine and BK21 Program for Veterinary Science Seoul National University Seoul Korea Conservation Genome Resource Bank for Korean Wildlife(CGRB) College of Veterinary Medicine and BK21 Program for Veterinary Science Seoul National University Seoul Korea National Veterinary Research & Quarantine Service Ministry of Agriculture and Forestry Anyang Korea National Veterinary Research & Quarantine Service Ministry of Agriculture and Forestry Anyang Korea

新城疫病是家禽的一种高度接触性、全身感染的病毒性疾病。它的致病因子,新城疫病毒(NDV)至少存在8个不同的基因群,是指 NDV 单一血清型中从基因型Ⅰ到Ⅷ。在韩国最近(自2000年)分离的毒株

关键词：猫头鹰新城疫病毒韩国流行株分离

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