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基于海绵城市理论的道路排水系统优化设计与施工要点

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工程建设与设计 2024年第14期 61-63页

作者：郭晓晖四川川交路桥有限责任公司市政公司四川广汉618300

快速降水产生的城市洪涝灾害和径流污染影响重大,需要在市政工程建设中融入多种控制技术,达到渗透、过滤、限流、存储等作用。论文从总体设计思路、排水横断面设计、组合排水设计、外部空间衔接设计等方面出发,分析了道路排水系统优化... 详细信息

快速降水产生的城市洪涝灾害和径流污染影响重大,需要在市政工程建设中融入多种控制技术,达到渗透、过滤、限流、存储等作用。论文从总体设计思路、排水横断面设计、组合排水设计、外部空间衔接设计等方面出发,分析了道路排水系统优化设计策略,研究了融入海绵城市理论的道路排水系统建设典型案例,总结了基础施工、储水箱施工、透水盲管安装、绿地施工等关键环节的施工要点,有利于提高设计与施工的衔接效果。

关键词：海绵城市理论道路排水系统优化设计施工要点

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隧道软岩大变形处治施工技术应用

工程建设与设计 2024年第16期 164-166页

作者：郭晓晖四川川交路桥有限责任公司市政公司四川广汉618300

研究了隧道软岩大变形处治施工技术应用,在掌握大变形形成机理的基础上,从开挖施工工法、大变形处治原则、锚杆施工技术、超前注浆小导管施工技术等方面出发,分析了隧道软岩大变形处治施工技术应用要点,明确软岩大变形的主要影响因素,... 详细信息

研究了隧道软岩大变形处治施工技术应用,在掌握大变形形成机理的基础上,从开挖施工工法、大变形处治原则、锚杆施工技术、超前注浆小导管施工技术等方面出发,分析了隧道软岩大变形处治施工技术应用要点,明确软岩大变形的主要影响因素,采用科学理论开展模拟分析,提高技术细节控制效果。

关键词：软岩大变形处治施工技术应用隧道施工

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数字化转型与银行风险承担

海南金融 2024年第9期 32-48页

作者：郭小卉姜铱然河北大学经济学院河北保定071000

基于2010—2021年中国109家商业银行的数据,从信息不对称视角分析银行数字化转型对银行风险承担的影响。实证结果显示,数字化转型能够显著降低银行风险承担。机制检验表明,银行利用数字技术获取海量信息,绘制用户画像,构建大数据征信体... 详细信息

基于2010—2021年中国109家商业银行的数据,从信息不对称视角分析银行数字化转型对银行风险承担的影响。实证结果显示,数字化转型能够显著降低银行风险承担。机制检验表明,银行利用数字技术获取海量信息,绘制用户画像,构建大数据征信体系,通过缓解信息不对称降低信贷风险,从而抑制银行风险承担。进一步研究发现,数字金融的发展会增强数字化转型对银行风险承担的抑制作用;数字化转型对东部地区银行或小规模银行风险承担的降低效果更好。本文扩展了数字化转型通过缓解信息不对称降低银行风险承担这一作用机制,为商业银行合理推进数字化转型、防范化解金融风险提供理论参考。

关键词：数字化转型银行风险承担商业银行信息不对称数字技术数字金融

Pay attention to individualized intensive glycemic control and reducing multiple risk factors of diabetes

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Chinese Medical Journal 2008年第8期121卷 675-676页

作者： guo xiao-hui Department of Endocrinology Peking University First Hospital Beijing 100034 China

As is well known, diabetes is becoming a significant burden for public health in China. Diabetes mellitus has become an epidemic in recent years in China. Studies indicate that the prevalence of diabetes has increased rapidly in many different areas of China. Type 2 diabetes mellitus is associated with a high rate of complications, including cardiovascular disease and diabetic nephropathy, retinopathy and neuropathy. The rate of death among patients with type 2 diabetes is approximately twice as high as that among persons without the disorder.

关键词： BLOOD-GLUCOSE CONTROL TYPE-2 COMPLICATIONS PREVALENCE MELLITUS DISEASE CHINA

Switching from human insulin to biphasic insulin aspart 30 treatment gets more patients with type 2 diabetes to reach target glycosylated hemoglobin 〈7%： the results from the China cohort of the PRESENT study

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Chinese Medical Journal 2010年第9期123卷 1107-1111页

作者： GAO Yan guo xiao-hui Department of Endocrinology Peiking University First HospitalBeijing 100034China

Background The clinical importance of glycaemic control in patients with diabetes has been well established. This study aimed to explore twice-daily biphasic insulin aspart 30 （BIAsp 30） for insulin initiation in patients with type 2 diabetes mellitus （T2DM） who had poor glycaemic control with human insulins （His）. We use data from a Chinese cohort of the PRESENT *** In the 3-month study, Chinese subjects with T2DM started insulin therapy with BIAsp 30 in routine care. Glycaemic control was measured by glycosylated hemoglobin （HbA1c）, fasting plasma glucose （FPG） and posting plasma glucose （PPG）. The safety assessment included hypoglycaemia and other adverse *** A total of 1989 subjects previously treated with His were switched to BIAsp 30 for 3-month treatment. Mean HbA1c, FPG and PPG were significantly improved after the therapy. The overall rate of hypoglycaemia decreased at the end of the trial except for the patients previously treated with long-acting insulin. Most of the events were minor and diurnal hypoglycaemia. Only one serious adverse drug reaction （SADR）, a local hypersensitivity, was reported. The majority of the patients （296.7%） and physicians （≥84.7%） were either satisfied or very satisfied with the treatment using BIAsp 30 compared with previous HI *** The BIAsp 30 treatment improved both glycaemic control and patients＇ satisfaction without increasing hypoglycaemia in T2DM subjects inadequately controlled by Hls.

关键词： diabetes mettitus, type 2 insulin hemoglobin A, glycosylated

浅析《中华人民共和国食品安全法》的修订历程与思考

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中国食物与营养 2024年第4期30卷 27-33页

作者：房昕瑜郭晓晖中国农业大学食品科学与营养工程学院北京100083

目的:对我国《中华人民共和国食品安全法》自颁布后的3次修订细节进行概述,对比分析我国与多个发达国家食品安全、食品卫生法律体系的异同。为国家食品安全法律保障工作提供相关参考建议。方法:通过关键词检索并筛选相关文献、书籍及网... 详细信息

目的:对我国《中华人民共和国食品安全法》自颁布后的3次修订细节进行概述,对比分析我国与多个发达国家食品安全、食品卫生法律体系的异同。为国家食品安全法律保障工作提供相关参考建议。方法:通过关键词检索并筛选相关文献、书籍及网络资料进行综述。结果:《中华人民共和国食品安全法》的修订给食品产业各利益相关方带来重要启示,与中国现阶段食品安全现状、未来食品发展趋势和国民营养与健康关系密切。结论:我国需加强食品安全法律法规的宣传工作,提高执法能力,加强社会舆论的监督管理,切实保障食品安全。

关键词：食品安全食品安全法法律修订食品监管社会共治

Genetic variability in adapter proteins with APPL1/2 is associated with the risk of coronary artery disease in type 2 diabetes mellitus in Chinese Han population

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Chinese Medical Journal 2011年第22期124卷 3618-3621页

作者： MA xiao-wei DING Shan MA xiao-dan GU Nan guo xiao-hui Department of Endocrinology Peking University First Hospital Beijing 100034 China

Background Adaptor proteins containing PH domain, PTB domain, and leucine zipper motif 1 and 2 （APPL1/2） play a key role in cell proliferation in many tissues. APPL1 or APPL2 as an adaptor for adiponectin receptors mediates the signaling pathway of adiponectin which acts as an anti-atherosclerotic adipokine. This study aimed to investigate whether genetic variations in the APPL 1/2 genes affect the risk of coronary artery disease （CAD） in Chinese patients with type 2 diabetes mellitus （T2DM）. Methods Seven haplotype-tagging single nucleotide polymorphisms （tag-SNPs） were selected from CHB HapMap database （Phase II） and total 203 CAD-positive cases and 106 CAD-negative controls with T2DM were genotyped for the 7 tag-SNPs by polymerase chain reaction-restriction fragment length polymorphism （PCR-RFLP） assay. Results The minor allele G of rs4640525 at APPL1 locus was protective from CAD in patients with T2DM, with the carriers of genotype CC at higher risk of CAD compared with non-carriers （OR=2.830, 95% Cl 1.285-6.230, P=0.010; OR＇=4.992, 95% C1=1.758-14.173, P＇0.003, after adjustment for the other known CAD risk factors）; the homozygotes of AA at rs11112412 in APPL2 gene had higher risk of CAD compared with those of GG （adjusted OFt=5.697, 95% Cl 1.006-32.257, P=0.049）. Conclusion Genetic variation（s） in APPL 1/2 may be associated with CAD risk in T2DM in Chinese population.

关键词： APPL1 APPL2 genes coronary artery disease, type 2 diabetes mellitus Chinese

FLOW PAST TWO ROTATING CIRCULAR CYLINDERS IN A SIDE-BY-SIDE ARRANGEMENT

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Journal of Hydrodynamics 2009年第2期21卷 143-151页

作者： guo xiao-hui LIN Jian-zhong TU Cheng-xu WANG Hao-li China Jiliang University Hangzhou 310018 China

Measurements were performed using Particle Image Velocimetry （PIV） to analyze the modification of flow by the combined effects of the rotation and the Reynolds number on the flow past two rotating circular cylinders in a side-by-side-arrangement at a range of 425 〈 Re ≤ 1130,0 ≤α ≤4 （ α is the rotational speed） at one gap spacing of T / d = 1.11 （T and d are the distance between the centers of two cylinders and the cylinder diameter, respectively）. A new Immersed-Lattice Boltzmann Method （ILBM） scheme was used to study the effect of the gap spacing on the flow. The results show that the vortex shedding is suppressed as rotational speed increases. The flow reaches a steady state when the vortex shedding for both cylinders is completely suppressed at critical rotational speed. As the rotational speed further increases, the separation phenomenon in the boundary layers disappears at the attachment rotational speed. The critical rotational speed and attachment rotational speed become small as Reynolds number increases. The absolute rotational speed of cylinders should be large at same critical rotational speed and attachment rotational speed in the case of large Reynolds number. The gap spacing has an important role in changing the pattern of vortex shedding. It is very different in the mechanism of vortex shedding suppression for the flows around two rotating cylinders and single rotating cylinder.

关键词： flow around two rotating cylinders side-by-side arrangement measurement simulation vortex shedding suppression

Mathematical Modeling and Effect of Various Hot-Air Drying on Mushroom(Lentinus edodes)

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Journal of Integrative Agriculture 2014年第1期13卷 207-216页

作者： guo xiao-hui XIA Chun-yan TAN Yu-rong CHEN Long MING Jian College of Food Science Southwest University Key Laboratory of Food Processing & Technology of Chongqing Laboratory of Quality & Safety Risk Assessment for Agro-products on Storage and Presevation (Chongqing) Ministry of Agriculture

An experimental study was performed to determine the characteristics and drying process of mushroom （Lentinus edodes） by 6 different hot-air drying methods namely isothermal drying, uniform raise drying, non-uniform raise drying, uniform intermittent drying, non-uniform intermittent drying and combined drying. The chemical composition （dry matter, ash, crude protein, crude fat, total sugars, dietary fiber, and energy）, color parameters （L, a＊, b＊, c＊, and h~） and rehydration capacities were determined. Among all the experiments, non-uniform intermittent drying reached a better comprehensive results due to the higher chemical composition, better color quality associated with high bright （26.381＋5.842）, high color tone （73.670＋2.975）, low chroma （13.349a：3.456） as well as the highest rehydration （453.76% weigh of dried body）. Nine kinds of classical mathematical model were used to obtained moisture data and the Midili-kucuk model can be described by the drying process with the coefficient （R2 ranged from 0.99790 to 0.99967）, chi-square （X2 ranged from 0.00003 to 0.00019） and root mean square error （RMSE ranged from 0.000486 to 0.0012367）.

关键词： Lentinus edodes hot-air drying mathematical model