检索结果-南通市图书馆

Clinical management of primary odontogenic sarcoma in the mandible:a case report after WHO nomination

在线全文

学校读者我要写书评

暂无评论

The Journal of Biomedical Research 2022年第1期36卷 68-72页

作者： Qinghai Zhu Chenxing Wang Yizhou Wang songsong guo Jinhai Ye Jiangsu Key Laboratory of Oral Diseases Nanjing Medical UniversityNanjingJiangsu 210029China Depatment of Oral and Maxillofacial Surgery the Affiliated Stomatological Hospital of Nanjing Medical UniversityNanjingJiangsu 210029China

Ameloblastic fibro-odontosarcoma(AFOS)now designated as odontogenic sarcoma is an extremely rare odontogenic tumor,which histologically presents as a biphasic neoplasm with a malignant mesenchymal component plus ameloblastic *** we report a 27-year-old Chinese female with the complaint of a painful swelling for half a month in the right mandible.A segmental mandibulectomy,with an immediate mandibular reconstruction using a free vascularized osteocutaneous fibular flap was performed using surgical guide *** analysis revealed a primary odontogenic *** postoperative period was uneventful,and no clinical indication of recurrence or metastasis was observed during the 3-year *** adjuvant therapy was *** is the first odontogenic sarcoma case reported in China after the new World Health Organization classification of odontogenic lesions.

关键词： odontogenic sarcoma ameloblastic fibrosarcoma ameloblastic fibro-odontosarcoma mandibular reconstruction

超声处理对Al-Si活塞合金组织和力学性能的影响

在线全文

学校读者我要写书评

暂无评论

热加工工艺 2017年第7期46卷 101-104页

作者：郭永春郭松松夏峰张振凯西安工业大学材料与化工学院陕西西安710021

对不同温度的Al-12Si-4Cu-Mg-2Ni活塞合金熔体进行了超声处理,研究了超声处理温度和超声功率对合金显微组织和力学性能的影响。结果表明,超声处理细化了初生Si、共晶Si,提升了合金力学性能。熔体温度为720℃时的细化效果优于650℃和690... 详细信息

对不同温度的Al-12Si-4Cu-Mg-2Ni活塞合金熔体进行了超声处理,研究了超声处理温度和超声功率对合金显微组织和力学性能的影响。结果表明,超声处理细化了初生Si、共晶Si,提升了合金力学性能。熔体温度为720℃时的细化效果优于650℃和690℃。熔体温度为720℃,超声功率为0~1400W时,初生Si的平均等积圆直径从40.73μm减小到23.35μm;共晶Si的平均长度从39.6μm减小到27.1μm;第二相的形态未发生改变;与未超声处理相比,合金的室温抗拉强度和350℃高温抗拉强度分别提高了21.9%和22.8%。

关键词： Al-Si合金超声处理活塞初生Si 共晶Si

盐霉素在白色链霉菌中的生物合成及代谢调控研究进展

在线全文

学校读者我要写书评

暂无评论

微生物学通报 2024年第3期51卷 732-742页

作者：郭松松孙羽杨怡萱余怡铖朱振洪浙江中医药大学生命科学学院浙江杭州310053

盐霉素(salinomycin)作为一种被广泛应用于畜牧业领域的重要抗生素,是具有抗肿瘤干细胞效果的一种潜在药物,其生物合成和代谢调控机制日益受到人们的关注。本文综述了白色链霉菌(Streptomyces albus)中盐霉素的生物合成机制及其次级代... 详细信息

盐霉素(salinomycin)作为一种被广泛应用于畜牧业领域的重要抗生素,是具有抗肿瘤干细胞效果的一种潜在药物,其生物合成和代谢调控机制日益受到人们的关注。本文综述了白色链霉菌(Streptomyces albus)中盐霉素的生物合成机制及其次级代谢调控研究的新进展,旨在通过对盐霉素生物合成基因簇关键蛋白、聚酮骨架链合成关键酶和调控因子的分析,提出通过次级代谢调控技术提高盐霉素产量的若干策略,为进一步开发盐霉素高产工业菌株提供参考。

关键词：盐霉素白色链霉菌生物合成代谢调控

掺土和施肥对铁尾矿基质理化性质及油松、樟子松幼苗生长的影响

在线全文

学校读者我要写书评

暂无评论

林业科学 2015年第5期51卷 12-20页

作者：张宝娟郭耸松李继泉李玉灵河北农业大学保定071000

【目的】砂寻求最合理的铁尾矿基质改良措施,为铁尾矿土壤改良与植被恢复提供理论依据。【方法】通过铁尾矿砂与无机肥、有机肥和土壤的不同配比处理的盆栽试验,研究不同改良方法对尾矿基质理化性质及油松和樟子松幼苗生长的影响。【结... 详细信息

【目的】砂寻求最合理的铁尾矿基质改良措施,为铁尾矿土壤改良与植被恢复提供理论依据。【方法】通过铁尾矿砂与无机肥、有机肥和土壤的不同配比处理的盆栽试验,研究不同改良方法对尾矿基质理化性质及油松和樟子松幼苗生长的影响。【结果】随无机肥施肥比例增加,铁尾矿土壤密度、田间持水量、毛管持水量、饱和持水量和总孔隙度与100%尾矿砂处理均无明显差异;随着有机肥施用量增加,田间持水量、毛管持水量、饱和持水量及总孔隙度均明显增大,土壤密度呈下降趋势,其中10%猪粪施肥配比与100%尾矿砂处理差异显著(P<0.05);随着掺土量增加,铁尾矿土壤密度逐渐降低,而田间持水量、毛管持水量、饱和持水量逐渐升高,掺土比例达到75%时,除了田间持水量,其他指标均与100%尾矿砂处理差异达到显著水平(P<0.05),电导率和土壤阳离子交换量、全氮全磷全钾养分含量、碱解氮、速效磷和速效钾含量均随施肥与掺土比例的增加而显著增大;10%猪粪施肥配比处理的全氮、全磷含量最大,分别是100%尾矿砂处理的6.38和3.33倍,碱解氮、速效磷和速效钾含量分别是100%尾矿砂处理的5.78,12.5和4.32倍;随掺土比例增大,尾矿中全磷含量减小,而掺土后全钾含量显著增高;掺土比例达到25%时,速效养分含量开始明显提升,客土处理达到最大值(78.41,44.43和58.67 mg·kg-1);施5%比例的有机肥和添加无机肥NH4NO31.76 g、KH2PO40.88 g的混合处理的速效养分含量与单纯施5%比例猪粪的单因子处理差异不明显;掺土比例25%和添加无机肥NH4NO31.76 g、KH2PO40.88 g混合处理的速效养分含量也和掺土比例25%的单因子处理无显著差异;掺土和施加无机肥会促进油松和樟子松幼苗的生长,施有机肥则会抑制它们的生长,相同处理情况下,油松较樟子松出苗率高、生长情况好。【结论】有机肥对铁尾矿基质的理化性质、全效养分含量和速效养分含量都有显著的改善作用,掺土处理对提高碱解氮、速效钾含量作用明显,但有机肥与无机肥、掺土与无机肥的混合配比对提升速效养分的效果不明显。不同处理对油松和樟子松的生长也会有不同程度的影响,表现为掺土和施加无机肥促进2树种生长,施加有机肥抑制2树种生长;在相同的处理情况下,油松比樟子松的生长要好,更适合作为铁尾矿废弃地修复树种。

关键词：铁尾矿改良措施基质理化性质植被恢复

数字化技术在口腔颌面部创伤治疗中的应用及展望

在线全文

学校读者我要写书评

暂无评论

口腔医学 2022年第1期42卷 36-41页

作者：郭松松张平程杰江宏兵南京医科大学附属口腔医院口腔颌面外科江苏省口腔疾病研究重点实验室江苏省口腔转化医学工程研究中心江苏南京210029

口腔颌面部创伤是口腔颌面外科常见疾病,常因颅脑外伤救治或区域医疗技术的限制,可能错过颌面伤的最佳治疗时机,然而,基于牙颌功能和面容外形重建的颌面创伤精准治疗是时代发展的新要求。较为系统的口腔颌面创伤治疗管理始于近代,从最... 详细信息

口腔颌面部创伤是口腔颌面外科常见疾病,常因颅脑外伤救治或区域医疗技术的限制,可能错过颌面伤的最佳治疗时机,然而,基于牙颌功能和面容外形重建的颌面创伤精准治疗是时代发展的新要求。较为系统的口腔颌面创伤治疗管理始于近代,从最初的简单缝合、夹板固定及钢丝结扎固定,到钛板坚固内固定,再到当前数字化技术辅助下的精准整复治疗,口腔颌面部创伤治疗取得了长足的进步。本文回溯了口腔颌面创伤的发展过程,介绍了目前数字化相关技术的具体应用,同时展望了其未来的发展趋势。

关键词：口腔颌面部创伤数字化技术导航

Reducing the measurement errors in nonadiabatic holonomic quantum computers

在线全文

学校读者我要写书评

暂无评论

Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 64-70页

作者： guo-Fu Xu Department of Physics Shandong University

Nonadiabatic holonomic quantum computers serve as the physical platform for nonadiabatic holonomic quantum *** quantum computation has entered the noisy intermediate-scale era, building accurate intermediate-scale nonadiabatic holonomic quantum computers is clearly necessary. Given that measurements are the sole means of extracting information, they play an indispensable role in nonadiabatic holonomic quantum computers. Accordingly, developing methods to reduce measurement errors in nonadiabatic holonomic quantum computers is of great importance. However, while much attention has been given to the research on nonadiabatic holonomic gates, the research on reducing measurement errors in nonadiabatic holonomic quantum computers is severely lacking. In this study, we propose a measurement error reduction method tailored for intermediate-scale nonadiabatic holonomic quantum computers. The reason we say this is because our method can not only reduce the measurement errors in the computer but also be useful in mitigating errors originating from nonadiabatic holonomic gates. Given these features,our method significantly advances the construction of accurate intermediate-scale nonadiabatic holonomic quantum computers.

关键词： quantum holonomy quantum computation measurement errors

Event-Triggered Optimal Nonlinear Systems Control Based on State Observer and Neural Network

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Systems Science & Complexity 2023年第1期36卷 222-238页

作者： CHENG songsong LI Haoyun guo Yuchao PAN Tianhong FAN Yuan Anhui Engineering Laboratory of Human-Robot Integration System and Intelligent Equipment School of Electrical Engineering and AutomationAnhui UniversityHefei 230601China Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education School of Electrical Engineering and AutomationAnhui UniversityHefei 230601China

This paper develops a novel event-triggered optimal control approach based on state observer and neural network(NN)for nonlinear continuous-time ***,the authors propose an online algorithm with critic and actor NNs to solve the optimal control problem and provide an event-triggered method to reduce communication and computation ***,the authors design weight estimation for critic and actor NNs based on gradient descent method and achieve uniformly ultimate boundednesss(UUB)estimation ***,by using bounded NN weight estimation and dead-zone operator,the authors propose a triggering condition,prove the asymptotic stability of closed-loop system from Lyapunov stability perspective,and exclude the Zeno ***,the authors provide a numerical example to illustrate the effectiveness of the proposed method.

关键词： Event-triggered control neural network optimal control state observer

Bandgap characteristics analysis and graded design of a novel metamaterial for flexural wave suppression

在线全文

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 1-24页

作者： Fan YANG Zhaoyang MA Xingming guo Shanghai Key Laboratory of Mechanics in Energy Engineering Shanghai Institute of Applied Mathematics and Mechanics School of Mechanics and Engineering ScienceShanghai University Shanghai Institute of Aircraft Mechanics and Control

A novel elastic metamaterial is proposed with the aim of achieving lowfrequency broad bandgaps and bandgap regulation. The band structure of the proposed metamaterial is calculated based on the Floquet-Bloch theorem, and the boundary modes of each bandgap are analyzed to understand the effects of each component of the unit cell on the bandgap formation. It is found that the metamaterials with a low elastic modulus of ligaments can generate flexural wave bandgaps below 300 Hz. Multi-frequency vibrations can be suppressed through the selective manipulation of bandgaps. The dual-graded design of metamaterials that can significantly improve the bandgap width is proposed based on parametric studies. A new way that can regulate the bandgap is revealed by studying the graded elastic modulus in the substrate. The results demonstrate that the nonlinear gradient of the elastic modulus in the substrate offers better bandgap performance. Based on these analyses, the proposed elastic metamaterials can pave the way for multi-frequency vibration control, low-frequency bandgap broadening, and bandgap tuning.

关键词：

Asking one mechanism in glial cells during neuroinflammation

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第4期20卷 1077-1078页

作者： Xiaoli guo Chikako Harada Takayuki Harada Visual Research Project Tokyo Metropolitan Institute of Medical ScienceTokyoJapan

Multiple sclerosis(MS),which is characterized by inflammatory demyelination in the central nervous system(CNS),is the most common neurological disease in the young adult *** autoimmune encephalomyelitis(EAE),an animal model of MS,is often used in preclinical *** data indicate that in addition to immune cells such as T cells and dendritic cells,CNS resident microglia and astrocytes play important roles in demyelinating neuroinflammation(Healy et al.,2022).In particular,microglia are key immune-competent cells that can respond to environmental *** depletion of transforming growth factor-β-activated kinase 1,a mitogen-associated protein kinase kinase kinase,in microglia is reported to reduce CNS inflammation and diminish axonal and myelin damage *** suggests that elucidating the mechanisms of microglia-specific responses during pathologies may help in the development of treatments that reduce EAE/MS disease severity(Goldmann et al.,2013).

关键词： inflammation clinical