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Study on the effect and mechanism of Yanghe decoction Huacai(阳和汤化裁) on tissue repair of Yin syndrome after anal fistula surgery

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Journal of Traditional Chinese Medicine 2024年第4期 813-821页

作者： WU Yijuan SUN Xinghong guo haixia ZHANG Xiangan Department of Anorectology the first Affiliated Hospital of Henan University of Chinese Medicine

OBJECTIVE: To observe the clinical efficacy and safety of Yanghe decoction Huacai(阳和汤化裁) for the repair of Yin syndrome wounds with slow-healing after anal fistula surgery. METHODS: A total of 120 patients with slow-healing negative wounds with after low-grade anal fistula surgery who met the inclusion criteria were divided into a treatment group and a control group based on a random number table method, with 60 patients in the treatment group and 60 patients in the control group. The treatment group was given Yanghe decoction Huacai in combination with routine treatment; the control group was only given routine treatment, in which the wound surface was disinfected with iodine, and then covered with sterile gauze. The course of treatment in both groups was 10 d. After treatment, the wound secretion score, wound granulation tissue score, the expression levels of basic fibroblast growth factor(bFGF), transforming growth factor β1(TGF-β1), and epidermal growth factor(EGF) in the wound, wound healing time and clinical efficacy were compared. RESULTS: There was no significant difference in age or gender between the two groups(P > 0.05). On the 10th and 15th days after the surgery, the wound secretion scores were higher in the treatment group than in the control group(P < 0.01). Comparing the two groups at the 10th and 15th day after surgery, the granulation tissue growth scores in the treatment group were better than the in control group(P < 0.01). On the 10th and 15th day after operation, the expression levels of bFGF, TGF-β1 and EGF factors in the treatment group were stronger than those in the control group. The healing time of the wounds in the treatment group was significantly shorter than in the control group(P < 0.01). The clinical efficacy of the two groups after treatment was compared, and the overall efficacy of the treatment group was significantly higher than that of the control group(P < 0.01). CONCLUSIONS: Yanghe decoction Huacai have significant efficacy in the treatment of slow-healing wounds with Yin

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Revealing the correlation between adsorption energy and activation energy to predict the catalytic activity of metal oxides for HMX using DFT

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Defence Technology（防务技术） 2024年第1期31卷 262-270页

作者： Xiurong Yang Chi Zhang Wujing Jin Zhaoqi guo Hongxu Gao Shiyao Niu Fengqi Zhao Bo Liu haixia Ma Xi'an Key Laboratory of Special Energy Materials School of Chemical EngineeringNorthwest UniversityXi'an710069China Science and Technology on Combustion and Explosion Laboratory Xi'an Modern Chemistry Research InstituteXi'an710065China Rocket Force University of Engineering Xi'an 710025China

Traditional selection of combustion catalysis is time-consuming and labor-intensive.Theoretical calculation is expected to resolve this problem.The adsorption energy of HMX and O atoms on 13 metal oxides was calculated using DMol3,since HMX and O are key substances in decomposition process.And the relationship between the adsorption energy of HMX,O on metal oxides(TiO_(2),Al_(2)O_(3),PbO,CuO,Fe_(2)O_(3),Co_(3)O_(4),Bi_(2)O_(3),NiO)and experimental T30 values(time required for the decomposition depth of HMX to reach 30%)was depicted as volcano plot.Thus,the T30 values of other metal oxides was predicted based on their adsorption energy on volcano plot and validated by previous experimental data.Further,the adsorption energy of HMX on ZrO_(2)and MnO_(2)was predicted based on the linear relationship between surface energy and adsorption energy,and T30 values were estimated based on volcano plot.The apparent activation energy data of HMX/MgO,HMX/SnO_(2),HMX/ZrO_(2),and HMX/MnO_(2)obtained from DSC experiments are basically consistent with our predicted T30 values,indicating that it is feasible to predict the catalytic activity based on the adsorption calculation,and it is expected that these simple structural properties can predict adsorption energy to reduce the large quantities of computation and experiment cost.

关键词： Density functional theory HMX Metal oxides Adsorption energy Activation energy

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Highly efficient nonuniform finite difference method for three-dimensional electrically stimulated liquid crystal photonic devices

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Photonics Research 2024年第4期12卷 865-875页

作者： ZHENGHAO guo MENGJUN LIU ZIJIA CHEN RUIZHI YANG PEIYUN LI haixia DA DONG YUAN guoFU ZHOU LINGLING SHUI HUAPENG YE Guangdong Provincial Key Laboratory of Optical Information Materials and Technology&Institute of Electronic Paper Displays South China Academy of Advanced OptoelectronicsSouth China Normal UniversityGuangzhou 510006China SCNU-TUE Joint Lab of Device Integrated Responsive Materials(DIRM) National Center for International Research on Green OptoelectronicsSouth China Normal UniversityGuangzhou 510006China Guangdong Provincial Key Laboratory of Nanophotonic Functional Materials and Devices School of Information and Optoelectronic Science and EngineeringSouth China Normal UniversityGuangzhou 510006China Joint Laboratory of Optofluidic Technology and Systems National Center for International Research on Green OptoelectronicsSouth China Academy of Advanced OptoelectronicsSouth China Normal UniversityGuangzhou 510006China College of Electronic and Optical Engineering&College of Microelectronics Nanjing University of Posts and TelecommunicationsNanjing 210046China Key Laboratory of Radio Frequency and Micro-Nano Electronics of Jiangsu Province Nanjing 210023China

Liquid crystal(LC)photonic devices have attracted intensive attention in recent decades,due to the merits of tunability,cost-effectiveness,and high efficiency.However,the precise and efficient simulation of large-scale three-dimensional electrically stimulated LC photonic devices remains challenging and resource consuming.Here we report a straightforward nonuniform finite difference method(NFDM)for efficiently simulating largescale LC photonic devices by employing a spatially nonuniform mesh grid.

关键词： nonuniform crystal finite

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Deletion of heterogeneous nuclear ribonucleoprotein K in satellite cells leads to inhibited skeletal muscle regeneration in mice

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Genes & Diseases 2024年第4期11卷 102-105页

作者： Yongjie Xu haixia Xu Xiaofang Cheng Nuo Chen Yaling Wang Yueru Huang Jiahua guo Yueqian Zheng Mengjia Zhang Chuunyu Du Cunzhen Zhao Cencen Li Pengpeng Zhang College of Life Science Xinyang Normal UniversityXinyangHenan 464000China Institute for Conservation and Utilization of Agro-Bioresources in Dabie Mountain Xinyang Normal UniversityXinyangHenan 464000China

Heterogeneous nuclear ribonucleoprotein K(hnRNPK)is a predominantly nuclear RNA-binding protein that can bind to DNA or RNA through three KH domains and interact with multiple proteins by interactive region.These binding activities enable hnRNPK to link the function in a wide array of diverse cellular processes,such as chromatin remodeling,gene transcription,RNA metabolism,protein translation,DNA repair,and cell signal transduction,thereby playing crucial roles in many biological processes,including development,axonal regeneration,spermatogenesis,cell cycle,apoptosis,differentiation,and carcinogenesis.

关键词： inhibited metabolism carcinogenesis

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Innovations in metallurgical and materials processes:advancing liquid theory and honoring Prof.Han-jie guo's contributions to physical chemistry in metallurgy

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Journal of Iron and Steel Research(International) 2024年第1期31卷 1-2页

作者： Shuai Liu Jing guo Han-jie guo School of Artificial Intelligence Beijing Technology and Business UniversityBeijing100048China School of Metallurgical and Ecological Engineering University of Science and Technology Beijing(USTB)Beijing100083China

Spanning three decades,Prof.Han-jie guo's research group has dedicated itself to exploring the fundamental theories and practical applications of physical chemistry within the realm of metallurgy.Operating under the a... 详细信息

关键词： chemistry liquid complexes

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Combining network pharmacology， molecular docking， and experimental verification to investigate the anti-rheumatoid arthritis effect and mechanism of Baeckea frutescens leaves

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Food Science and Human Wellness 2024年

作者： Xueyang guo Mengyao Zhang haixia Cai Xinyue Jiang Siyuan Zhou Wen Gong Zijiao Wei Weili Qiao Beixi Jia Department of Pharmacognosy School of Pharmaceutical Science Zhengzhou University Department of Pharmacy Henan Provincial People's Hospital

The aromatic Baeckea frutescens leaves (BFL) known as “Gang-Song-Cha” is a popular drink (Tea) in South China. To explore the healthcare value， a systematic and in-depth study on BFL alleviating rheumatoid arthritis (RA) was carried out by integrating network pharmacology， molecular docking， and experimental verification. The efficacy was first evaluated， and the BFL extract could ameliorate RA by inhibiting articular swelling， lowering immune organ index， improving the ankle pathologies， and regulating serum levels of TNF-α， IL-6， and IL-10 in CIA rats. Then the anti-RA mechanism of BFL was investigated by leveraging the high-content and active component 5-hydroxy-7-methoxy-2-isopropylchromone (Chro.)， and the potential signaling pathway and related target proteins for Chro. acting on RA were analyzed by KEGG enrichment and docking simulation. Finally， the experimental validations were conducted on RA-FLS cells， and compound Chro. could inhibit cell invasion and migration， block cell cycle at G2/M phase and induce apoptosis， and reduce the secretion of inflammatory cytokines by suppressing the PI3K-Akt pathway. These results provided pharmacological basis for the folk usage of “Gang-Song-Cha (Tea)” for intervening RA.

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Light People:Prof.Eric Mazur speaks about ultrafast optics and education

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Light(Science & Applications) 2024年第3期13卷 402-406页

作者： Chenzi guo Yang Li Changchun Institute of Optics Fine Mechanics and PhysicsChinese Academy of SciencesChangchunChina State Key Laboratory of Precision Measurement Technology and Instrument Department of Precision InstrumentTsinghua UniversityBeijingChina

Prof.Eric Mazur is a great influencer over and beyond the optics community.As a physicist,he is a pioneer of ultrafast optics and was one of the inventors of colliding-pulse mode-locked laser.As an educator,he not only gave talks to thousands,but also revolutionized teaching with his globally renowned methodology“Peer Instruction”.As a leader and entrepreneur,he co-founded several companies and was President of Optica(formerly the Optical Society)and currently is the Chair of the Optica Foundation.Here,Light:Science&Applications talked with Prof.Eric Mazur about his opinions on research,education and industry.The full interview video can be found in the Supplementary File.

关键词： optics education companies

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Emerging direct current triboelectric nanogenerator for high-entropy mechanical energy harvesting

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Science China(Technological Sciences) 2024年第5期67卷 1297-1316页

作者： CHEN Jie guo RuiLong guo HengYu College of Physics and Electronic Engineering Chongqing Normal UniversityChongqing 401331China Department of Applied Physics Chongqing UniversityChongqing 401331China

In the era of the Internet of Things(IoT),the provision of sustainable power to distributed,mobile,and low-power-consumption electronic devices is a critical challenge.To overcome this challenge,the triboelectric nanogenerator(TENG),a highly efficient high-entropy mechanical energy harvesting device,was developed in 2012.This device enables the direct conversion of irregular and low-frequency mechanical energy into pulsed alternating current(AC)signals.However,the incompatibility of most electronic devices with AC signals necessitates rectifier circuits or generators that deliver direct current(DC)signals.In recent years,DC-TENGs have undergone extensive development,achieving significant milestones in various application fields while also facing crucial challenges that require solutions.In this review,three categories of DC-TENG devices with distinct operating mechanisms are comprehensively explored:multiphase coupling,mechanical rectification,and air breakdown.Their typical structures and working mechanisms are thoroughly discussed,and specific output performance limitations,along with corresponding optimization strategies,are identified.Furthermore,the applications of DC-TENGs in various scenarios are summarized.Finally,the challenges faced by DC-TENGs and potential solutions are analyzed to guide further advancements in this technology.

关键词： TENG direct current working mechanisms output performance limitations optimization strategies

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Light People:Prof.Kei May Lau,newly elected US NAE member in Hong Kong,talks about future of photonics and women in science

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Light(Science & Applications) 2024年第4期13卷 602-608页

作者： Yating Wan Chenzi guo Electrical and Computer Engineering the ComputerElectrical and Mathematical Sciences and Engineering DivisionKing Abdullah University of Science and Technology23955-6900 ThuwalSaudi Arabia Changchun Institute of Optics Fine Mechanics and PhysicsChinese Academy of SciencesChangchunChina

Editorial Photonics technology remains a driving force in today’s scientific landscape,marked by continuous innovation and crossdisciplinary relevance.In an enlighting conversation with Light:Science&Applications,Prof.Kei May Lau,a pioneer in photonics research,shares her deep insights on the evolution of technologies of LEDs,lasers,challenges of hetero-epitaxy,and the future of micro-LEDs and quantum dot lasers.Recently honored as a member of the US National Academy of Engineering(NAE)for her significant contributions to photonics and electronics using III-V semiconductors on silicon,Prof.Lau stands out as the sole Hong Kong scholar inducted into the NAE this year,joining 114 new and 21 international members.In this exclusive Light People interview,Prof.Lau shares her journey as a pioneering woman in engineering,her commitment to mentorship and academia,and her perspective on advancing female representation in science.The summary provided is distilled from Prof.Lau’s thoughtful responses during the interview.For a deeper exploration of Prof.Lau’s experiences and advice,the full interview is available in the Supplementary material.

关键词： interview lighting driving

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Improving benzene catalytic oxidation on Ag/Co_(3)O_(4) by regulating the chemical states of Co and Ag

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Journal of Environmental Sciences 2024年第9期143卷 201-212页

作者： Hao guo Tao guo Mengqi Zhao Yaxin Zhang Wenfeng Shangguan Yinnian Liao State Key Laboratory of Chemistry and Utilization of Carbon Based Energy Resources Xinjiang UniversityXinjiang 830017China Xinjiang Key Laboratory of Coal Clean Conversion&Chemical Engineering Process Xinjiang UniversityXinjiang 830017China School of Chemical Engineering and Technology Xinjiang UniversityXinjiang 830017China Research Center for Combustion and Environmental Technology Shanghai Jiao Tong UniversityShanghai 200240China School of Applied Chemistry and Materials Zhuhai College of Science and TechnologyGuangdong 519041China

Silver(9 wt.%)was loaded on Co_(3)O_(4)-nanofiber using reduction and impregnation methods,respectively.Due to the stronger electronegativity of silver,the ratios of surface Co^(3+)/Co^(2+) on Ag/Co_(3)O_(4) were higher than on Co_(3)O_(4),which further led to more adsorbed oxygen species as a result of the charge compensation.Moreover,the introducing of silver also obviously improved the reducibility of Co_(3)O_(4).Hence the Ag/Co_(3)O_(4) showed better catalytic performance than Co_(3)O_(4) in benzene oxidation.Compared with the Ag/Co_(3)O_(4) synthesized via impregnation method,the one prepared using reduction method(named as Ag Co-R)exhibited higher contents of surface Co^(3+) and adsorbed oxygen species,stronger reducibility,as well as more active surface lattice oxygen species.Consequently,Ag Co-R showed lowest T_(90) value of 183℃,admirable catalytic stability,largest normalized reaction rate of1.36×10^(-4)mol/(h·m^(2))(150℃),and lowest apparent activation energy(E_(a))of 63.2 kJ/mol.The analyzing of in-situ DRIFTS indicated benzene molecules were successively oxidized to phenol,o-benzoquinone,small molecular intermediates,and finally to CO_(2) and water on the surface of Ag Co-R.At last,potential reaction pathways including five detailed steps were proposed.

关键词： Reduction method Co_(3)O_(4)-supported Ag catalyst,VOCs Benzene oxidation Reaction mechanism

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