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Animal Nutrition 2023年第4期15卷 210-224页

作者： Long Yuan Chuyang Zhu fang gu Miaonan Zhu Jiacheng Yao Cuipeng Zhu Shicheng Li Kun Wang Ping Hu Yunzeng Zhang Demin Cai Hao-Yu Liu College of Animal Science and Technology Yangzhou UniversityYangzhou 225009China Joint International Research Laboratory of Agricultural&Agri-Product Safety The Ministry of Education of ChinaYangzhou UniversityYangzhou 225009China Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses Yangzhou UniversityYangzhou 225009China

Developing effective strategies to prevent diarrhea and associated-gut disorders in mammals has gained great *** to the many health benefits provided by the commensal microbiota of the intestinal tract,such as against environmental perturbation,we explored the host phenotype-associated microbes and their probiotic *** on the observations that the chronic heat stress-exposed weaned piglets present as heat stress-susceptible(HS-SUS)or heat stress-resistant(HS-RES)individuals,we confirmed the phenotypic difference between the two on growth performance(Pgulation(Pgut microbiome using 16S rRNA gene sequencing and KEGG functional analysis,we found that Lactobacillus johnsonii exhibited significantly higher relative abundance in the HS-RES piglets than in the HS-SUS ones(Pgulatory T(Treg)cell numbers(P<0.05),and decreased the Th17 population and its IL-17a production under physiological condition and during colitis(P<0.01).Our results shed light on understanding the interaction between commensal Lactobacillus and the host health,and provide *** N5 as an alternative to antibiotics for p

关键词： Lactobacillus johnsonii Probiotic Heat shock protein Diarrhea Heat stress Treg/Th17

OsFKBP1 interacts with phytochrome B in rice

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Progress in Natural Science:Materials International 2009年第11期19卷 1523-1528页

作者： Suhai gu,fang Zhang,Naihu Wu~* Institute of Genetics and Developmental Biology,Chinese Academy of Sciences,3 Zhongguancunnanyitiao,Beijing 100080,China [a]Institute of Genetics and Developmental Biology Chinese Academy of Sciences 3 Zhongguancunnanyitiao Beijing 100080 China

Part of the C-terminal of rice phytochrome B was used as bait to screen a cDNA library constructed from young rice panicles in a yeast two-hybrid screening.A positive clone was selected,and the sequence was characterized as encoding a FKBP protein,which is a putative developmental *** in vitro pull-down assay using recombinant proteins and analysis of bimolecular fluorescence complementation in onion epidermal cells indicated that two proteins interact in vitro and in *** results of reverse transcription polymerase chain reaction showed that two genes were co-expressed in the examined rice organs,suggesting that OsFKBP1 may play a role in light signal transduction in rice.

关键词： Rice Yeast two hybrid Phytochrome BiFC

LiNi_(0.78)Co_(0.2)Zn_(0.02)O_2的制备及物理性质对其电化学性能的影响

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哈尔滨工业大学学报 2006年第9期38卷 1605-1607,1612页

作者：高农谷芳顾大明黑龙江工程学院电子工程系哈尔滨150050 哈尔滨工业大学应用化学系哈尔滨150001

采用共沉淀法,制备了具有良好电化学性能的层状L iN i0.78Co0.2Zn0.02O2正极材料,探讨材料的物理性质对其电化学性能的影响.结果表明:电极片涂膜的厚度对其放电比容量及循环性能有很大影响;粒径的大小对首次放比容量的影响不大,但对其... 详细信息

采用共沉淀法,制备了具有良好电化学性能的层状L iN i0.78Co0.2Zn0.02O2正极材料,探讨材料的物理性质对其电化学性能的影响.结果表明:电极片涂膜的厚度对其放电比容量及循环性能有很大影响;粒径的大小对首次放比容量的影响不大,但对其长期循环性能的影响较大.材料的相变是放电容量衰减的主要因素之一,通过掺杂改性、优化制备工艺条件、控制材料的物理性质,有利于抑制相变,提高材料的电化学性能.

关键词： LiNi0.78Co0.2Zn0.02O2 正极材料物理性质电化学性能

Division of Free Nuclei in Rice Endosperm and Its Influencing Factors

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Rice science 2009年第2期16卷 131-137页

作者： LIU Man-xi WANG Zhong WU Xiao-mei CHEN Yi-fang gu Yun-jie Key Laboratory of Crop Genetics ＆ Physiology of Jiangsu Province Yangzhou University Yangzhou 225009 China

The division process of endosperm in rice and its influencing factors were investigated. Total dissection, resin embedding and sectioning under light and transmission electron microscopes were used to observe the division patterns of free nuclei and cytological characters of an endosperm. The various division patterns of free nuclei in rice endosperm included mitosis, amitosis, and the mitosis to amitosis change without an interphase. The division velocity of free nuclei in rice endosperm varied with the internucleus distance. Comparing to a cluster, the division velocity increased when the free nuclei were separated from each other. Moderately higher temperatures also enhanced the proliferation and shortened the division cycle of free nuclei in rice endosperm. To a certain extent, nitrogenous fertilizer applied at the booting stage together with a moderate drought treatment accelerated the division of free nuclei as well.

关键词： rice endosperm free nuclei division pattern cytology water management nitrogen application temperature

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不孕症合并子宫内膜息肉的临床处理及预后

中国实用妇科与产科杂志 2020年第6期36卷 491-495页

作者：古芳中山大学附属第一医院生殖中心广东广州510080

子宫内膜息肉是最常见的良性子宫内膜病变之一,可能通过机械梗阻和炎症刺激影响妊娠的发生而导致不孕。经阴道超声是内膜息肉的主要筛查手段,宫腔镜检查及直视下病理活检则是内膜息肉诊断的金标准。宫腔镜手术切除息肉可以提高自然妊娠... 详细信息

子宫内膜息肉是最常见的良性子宫内膜病变之一,可能通过机械梗阻和炎症刺激影响妊娠的发生而导致不孕。经阴道超声是内膜息肉的主要筛查手段,宫腔镜检查及直视下病理活检则是内膜息肉诊断的金标准。宫腔镜手术切除息肉可以提高自然妊娠和辅助生殖技术的成功率,然而息肉切除是否作为辅助生殖技术实施前的常规治疗目前尚有争议。子宫内膜息肉术后复发的预防、促排卵过程中新发息肉的处理是目前的两个临床难题,需要一系列设计严谨的临床及基础研究为息肉的处理提供更有说服力的理论和实践依据。

关键词：子宫内膜息肉不孕症息肉切除术

Proteomic investigations of acute ischemic stroke in animal models:a narrative review

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Journal of Bio-X Research 2023年第1期6卷 15-22页

作者： fangxu Sun Rong-fang gu Ru Wei Chemical Biology and Proteomics BiogenCambridgeMAUSA

Acute ischemic stroke(AIS),a neurological injury resulting from blood clots,is the second most common cause of death *** therapeutics are urgently *** developments in instrumentation and bioinformatics have resulted in increased use of mass spectrometry-based proteomics as an effective tool for the in-depth study of *** review focuses on proteomics investigations of AIS in animal *** highlight the study findings in system-wide protein abundance changes and molecular mechanisms underlying AIS with or without therapeutic intervention,as well as prestroke prognosis *** review reveals that common molecular pathways related to ischemic injury and spontaneous recovery have been uncovered and part of AIS-changed proteins have been repeatedly identified,indicating the promise of proteomics in generating novel therapeutic targets and biomarker *** also discuss challenges,alleviating strategies,and perspectives of mass spectrometry-based proteomics in AIS research and call for a broad application of systems-level investigations on preclinical AIS molecular mechanism elucidation,target discovery and validation,and therapeutics development.

关键词： acute ischemic stroke ischemic molecular mechanism MCAO model proteomics stroke biomarker

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良渚玉器部分玉料来源的蠡测

华夏考古 2007年第1期 75-79页

作者：古方北京玉学玉文化研究中心北京市100710

良渚文化玉器中,有一种玉器的玉质细腻纯净,透明度较高,颜色为黄绿和深浅不一的绿色。这类玉料的外观与江浙一带所产玉料截然不同,而与辽东半岛岫岩所产软玉极为相似。因此,良渚玉器部分玉料可能采源于辽东半岛。岫岩软玉的传输路线,是... 详细信息

良渚文化玉器中,有一种玉器的玉质细腻纯净,透明度较高,颜色为黄绿和深浅不一的绿色。这类玉料的外观与江浙一带所产玉料截然不同,而与辽东半岛岫岩所产软玉极为相似。因此,良渚玉器部分玉料可能采源于辽东半岛。岫岩软玉的传输路线,是从辽东半岛南部沿海出发,渡过渤海海峡到达胶东半岛,再向西南入山东腹地,折向南到江苏北部进入良渚文化分布区。在这条玉材传送路线上起运输中转作用的,是辽东半岛的原始部落和以大汶口、龙山文化为代表的山东地区原始部落。

关键词：良渚玉器辽东半岛玉料传输

单链高分子通过薄膜上纳米孔隙的输运过程:链间相互作用的影响

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高等学校化学学报 2006年第7期27卷 1343-1346页

作者：王海军顾芳河北大学化学与环境科学学院

从理论上研究了高分子链通过位于薄膜上的一个纳米孔隙的输运问题.考虑在膜的一侧引入与传输高分子链有特殊相互作用的高分子链段,研究链间相互作用致使高分子链构型的改变对其平均首次通过时间的影响,进而在不同条件下进行了相应的数... 详细信息

从理论上研究了高分子链通过位于薄膜上的一个纳米孔隙的输运问题.考虑在膜的一侧引入与传输高分子链有特殊相互作用的高分子链段,研究链间相互作用致使高分子链构型的改变对其平均首次通过时间的影响,进而在不同条件下进行了相应的数值模拟,并讨论了其它一些相关问题.

关键词：纳米孔隙氢键平均首次通过时间

Human activities and elevational constraints restrict ranging patterns of snub-nosed monkeys in a mountainous refuge

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Integrative Zoology 2021年第2期16卷 202-213页

作者： Pengzhen HUANG Kun BIAN Zhipang HUANG Qi Li Derek WDUNN gu fang Jiahui LIU Mengyao WANG Xianfeng YANG Ruliang PAN Cunlao GAO Kaichuang SI Baoguo LI Xiaoguang QI Shaanxi Key Laboratory for Animal Conservation College of Life SciencesNorthwest UniversityXi’anChina Shaanxi Institute of Zoology Xi’anChina Zhouzhi National Nature Reserve Xi’anChina Center for Excellence in Animal Evolution and Genetics Chinese Academy of SciencesKunmingChina

Both natural conditions and anthropogenic factors affect the survivability,distribution,and population density of *** understand the extent and how these factors drive species distributions,a detailed description of animal movement patterns in natural habitats is *** this study,we used satellite telemetry to monitor elevational ranges favored by endangered golden snub-nosed monkeys(Rhinopithecus roxellana),in the Qinling Mountains,central *** investigated the abundance and distribution of food resources through sampling vegetation quadrats at different elevations and sampled anthropogenic activities using field *** results indicated that although there was no significant variation in food resources between low-(<1500 m)and middle-elevations(1500–2200 m),monkeys were found most often in areas above 1500 m,where there was less anthropogenic development(*** and roads);however,monkeys rarely ranged above 2200 m and had limited food availability at this *** was limited human disturbance at this *** suggest that both human activity and ecological constraints(*** resources)have considerable effects on elevational use of *** in the Qinling *** study highlights the critical roles these factors can play in shaping the vertical distribution of high-altitude *** research provides useful insights for habitat-based conservation plans in which human disturbance management and habitat restoration should be prioritized.

关键词： elevational distribution food resources human activity Rhinopithecus roxellana satellite telemetry

缔合流体中胶体粒子间耗尽势的密度泛函理论研究

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高等学校化学学报 2011年第7期32卷 1567-1572页

作者：顾芳王海军河北大学化学与环境科学学院教育部药物化学与分子诊断重点实验室保定071002 中国科学院国际材料物理中心沈阳110016

基于与耗尽势相关的密度泛函理论,研究了缔合流体中胶体粒子间的耗尽势.通过计算不同条件下2个胶体粒子间的耗尽势,进一步分析了缔合流体中相关因素对耗尽势的影响.结果表明,溶剂分子的体相密度、胶体粒子与溶剂分子的尺寸比率、溶剂分... 详细信息

基于与耗尽势相关的密度泛函理论,研究了缔合流体中胶体粒子间的耗尽势.通过计算不同条件下2个胶体粒子间的耗尽势,进一步分析了缔合流体中相关因素对耗尽势的影响.结果表明,溶剂分子的体相密度、胶体粒子与溶剂分子的尺寸比率、溶剂分子的官能度和缔合强度及胶体粒子与溶剂分子之间的弱相互作用等因素均可对胶体粒子间耗尽势产生显著影响.

关键词：耗尽势密度泛函理论胶体粒子缔合流体