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基于改进的think-pair-share混合式教学在药学专业英语教学中的应用研究

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中国高等医学教育 2024年第3期 119-121页

作者：王虹葛燕青张宏志山东第一医科大学化学与制药工程学院山东泰安271016 山东第一医科大学通识教育部山东济南250117

该研究以2018级药学专业本科2个班为研究对象,试验组采取改进的think-pair-share混合式教学,对照组采用传统教学模式。通过对两组学生考试成绩、单元测验成绩、SRSSDL评分,探索改进的think-pair-share混合式教学在医学相关专业教学中的... 详细信息

该研究以2018级药学专业本科2个班为研究对象,试验组采取改进的think-pair-share混合式教学,对照组采用传统教学模式。通过对两组学生考试成绩、单元测验成绩、SRSSDL评分,探索改进的think-pair-share混合式教学在医学相关专业教学中的应用效果。结果显示,试验组学生期末考试成绩、单元测验成绩、SRSSDL量表评分均明显高于对照组(P<0.05,P<0.01)。改进的think-pair-share混合式教学能显著提升学生的主动学习和自我效能,有望在医药相关专业教学中推广应用。

关键词：改进 think-pair-share 混合式药学专业英语

Investigation of high rate mechanical flow followed by ignition for high-energy propellant under dynamic extrusion loading

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Defence Technology（防务技术） 2024年第2期32卷 336-347页

作者： Liying Dong yanqing Wu Kun Yang Xiao Hou State Key Laboratory of Explosion Science and Technology Beijing Institute of TechnologyBeijing 100081China School of Aerospace Engineering Beijing Institute of TechnologyBeijing 100081China

Investigating the ignition response of nitrate ester plasticized polyether(NEPE) propellant under dynamic extrusion loading is of great significant at least for two cases. Firstly, it helps to understand the mechanism and conditions of unwanted ignition inside charged propellant under accident ***, evaluates the risk of a shell crevice in a solid rocket motor(SRM) under a falling or overturning scene. In the present study, an innovative visual crevice extrusion experiment is designed using a dropweight apparatus. The dynamic responses of NEPE propellant during extrusion loading, including compaction and compression, rapid shear flow into the crevice, stress concentration, and ignition reaction, have been firstly observed using a high-performance high-speed camera. The ignition reaction is observed in the triangular region of the NEPE propellant sample above the crevice when the drop weight velocity was 1.90 m/s. Based on the user material subroutine interface UMAT provided by finite element software LS-DYNA, a viscoelastic-plastic model and dual ignition criterion related to plastic shear dissipation are developed and applied to the local ignition response analysis under crevice extrusion conditions. The stress concentration occurs in the crevice location of the propellant sample, the shear stress is relatively large, the effective plastic work is relatively large, and the ignition reaction is easy to occur. When the sample thickness decreases from 5 mm to 2.5 mm, the shear stress increases from 22.3 MPa to 28.6 MPa, the critical value of effective plastic work required for ignition is shortened from 1280 μs to 730 μs, and the triangular area is easily triggering an ignition reaction. The propellant sample with a small thickness is more likely to stress concentration, resulting in large shear stress and effective work, triggering an ignition reaction.

关键词： NEPE propellant Crevice extrusion Shear flow Sample thickness Ignition reaction

Comparisons of Wave Force Model Effects on the Structural Responses and Fatigue Loads of a Semi-Submersible Floating Wind Turbine

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Journal of Ocean University of China 2024年第1期23卷 69-79页

作者： HAN yanqing LE Conghuan ZHANG Puyang XU Shengnan State Key Laboratory of Hydraulic Engineering Simulation and Safety Tianjin UniversityTianjin 300072China School of Hydraulic Engineering Ludong UniversityYantai 264025China School of Civil Engineering Tianjin UniversityTianjin 300072China Shandong Marine Aerospace Equipment Technological Innovation Center Yantai 264004China

The selection of wave force models will significantly impact the structural responses of floating wind *** this study,comparisons of wave force model effects on the structural responses and fatigue loads of a semi-submersible floating wind turbine(SFWT)were *** were performed by employing the Morison equation(ME)with linear or second-order wave kinematics and potential flow theory(PFT)with first-or second-order wave forces.A comparison of regular waves,irregular waves,and coupled wind/waves analyses with the experimental data showed that many of the simulation results and experimental data are relatively ***,notable discrepancies are found in the response amplitude operators for platform heave,tower base bending moment,and tension in mooring *** models give more satisfactory results of heave but more significant discrepan-cies in tower base bending moment than the ME *** irregular wave analyses,low-frequency resonances were captured by PFT models with second-order difference-frequency terms,and high-frequency resonances were captured by the ME models or PFT models with second-order sum-frequency *** force models capture the response frequencies but do not reasonably predict the response *** coupled wind/waves analyses showed more satisfactory results than the wave-only ***,an important detail to note is that this satisfactory result is based on the overprediction of wind-induced responses.

关键词： floating wind turbine wave force model potential flow theory Morison equation second-order wave forces

Peripheral Mechanism of Cancer-Induced Bone Pain

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Neuroscience Bulletin 2024年第6期40卷 815-830页

作者： Yachen Yang Wei Yang Ruofan Zhang yanqing Wang Department of Integrative Medicine and Neurobiology School of Basic Medical SciencesShanghai Medical CollegeInstitute of Acupuncture ResearchInstitutes of Integrative MedicineFudan UniversityShanghai200032China Shanghai Key Laboratory of Acupuncture Mechanism and Acupoint Function Shanghai Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain ScienceInstitutes of Brain ScienceFudan UniversityShanghai200032China Zhongshan-Fudan Joint Innovation Center Zhongshan528437China

Cancer-induced bone pain(CIBP)is a type of ongoing or breakthrough pain caused by a primary bone tumor or bone *** constitutes a specific pain state with distinct characteristics;however,it shares similarities with inflammatory and neuropathic *** present,although various therapies have been developed for this condition,complete relief from CIBP in patients with cancer is yet to be ***,it is urgent to study the mechanism underlying CIBP to develop efficient analgesic ***,we focused on the peripheral mechanism associated with the initiation of CIBP,which involves tissue injury in the bone and changes in the tumor microenvironment(TME)and dorsal root *** nerve–cancer and cancer–immunocyte cross-talk in the TME creates circumstances that promote tumor growth and metastasis,ultimately leading to *** peripheral mechanism of CIBP and current treatments as well as potential therapeutic targets are discussed in this review.

关键词： Cancer-induced bone pain Peripheral mechanism Tumor microenvironment Sensory nerve Immunocytes

Shock-induced energy localization and reaction growth considering chemical-inclusions effects for crystalline explosives

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Defence Technology（防务技术） 2024年第3期33卷 278-294页

作者： Ruqin Liu yanqing Wu Xinjie Wang Fenglei Huang Xiaona Huang Yushi Wen State Key Laboratory of Explosion Science and Technology Beijing Institute of TechnologyBeijing100081China School of Power and Mechanical Engineering Wuhan UniversityWuhan430072HubeiChina Institute of Chemical Materials China Academy of Engineering Physics(CAEP)Mianyang621999SichuanChina

Chemical inclusions significantly alter shock responses of crystalline explosives in macroscale gap experiments but their microscale dynamics origin remains *** shock-induced energy localization,overall physical responses,and reactions in a-1,3,5-trinitro-1,3,5-triazinane(a-RDX)crystal entrained various chemical inclusions were investigated by the multi-scale shock technique implemented in the reactive molecular dynamics *** indicated that energy localization and shock reaction were affected by the intrinsic factors within chemical inclusions,i.e.,phase states,chemical compositions,and *** atomic origin of chemical-inclusions effects on energy localization is dependent on the dynamics mechanism of interfacial molecules with free space volume,which includes homogeneous intermolecular compression,interfacial impact and shear,and void collapse and *** introducing various chemical inclusions,the initiation of those dynamics mechanisms triggers diverse decay rates of bulk RDX molecules and hereby impacts on growth speeds of final *** chemical inclusions can reduce the effectiveness of the void during the shock *** the shockwave velocity of 9 km/s,the parent RDX decay rate in RDX entrained amorphous carbon decreases the most and is about one fourth of that in RDX with a vacuum void,and solid HMX and TATB inclusions are more reactive than amorphous carbon but less reactive than dry air or acetone *** lessdense shocking system denotes the greater increases in local temperature and stress,the faster energy liberation,and the earlier final reaction into equilibrium,revealing more pronounced responses to the present intense *** quantitative models associated with the relative system density(RD_(sys))were proposed for indicating energy-localization mechanisms and evaluating initiation safety in the shocked crystalline ***_(sys)is defined by the density ratio of defective RDX to perfec

关键词： Shock responses Energy localization Crystalline explosives Chemical inclusions Reactive molecular dynamics

Hollow Ni Mo-based nitride heterojunction with super-hydrophilic/aerophobic surface for efficient urea-assisted hydrogen production

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Journal of Energy Chemistry 2024年第8期95卷 428-439,I0009页

作者： Yuying Fan Ying Gu Dongxu Wang yanqing Jiao Aiping Wu Chungui Tian Key Laboratory of Functional Inorganic Material Chemistry Ministry of Education of the People’s Republic of ChinaHeilongjiang UniversityHarbin 150080HeilongjiangChina College of Chemistry Chemical Engineering and Resource UtilizationNortheast Forestry UniversityHarbin 150040HeilongjiangChina

Hydrogen evolution reaction(HER)and urea oxidation reaction(UOR)are key reactions of the watercycling associated catalytic process/*** design of catalysts with a super-hydrophilic/aerophobic structure and optimized electron distribution holds great ***,we have designed a threedimensional(3D)hollow Ni/NiMoN hierarchical structure with arrayed-sheet surface based on a onepot hydrothermal route for efficient urea-assisted HER based on a simple hydrothermal *** Ni/NiMoN catalyst exhibits super-hydrophilic/aerophobic properties with a small droplet contact angle of 6.07°and an underwater bubble contact angle of 155.7°,thus facilitating an escape of bubbles from the *** functional theory calculations and X-ray photoelectron spectroscopy results indicate the optimized electronic structure at the interface of Ni and NiMoN,which can promote the adsorption/desorption of reactants and *** virtues combining with a large specific surface area endow Ni/NiMoN with efficient catalytic activity of low potentials of 25 mV for HER and 1.33 V for UOR at10 mA cm^(-2).The coupled HER and UOR system demonstrates a low cell voltage of 1.42 V at 10 mA cm^(-2),which is approximately 209 mV lower than water electrolysis.

关键词： Hydrogen evolution Transition metal nitrides Hollow heterojunctions Urea electrooxidation Super hydrophilic/aerophobic

Hole mobility enhancement in monolayer WSe2 p-type transistors through molecular doping

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Science China(Information Sciences) 2024年第6期67卷 207-213页

作者： Shiyuan LIU Xiong XIONG Xin WANG Xinhang SHI Ru HUANG yanqing WU School of Integrated Circuits and Beijing Advanced Innovation Center for Integrated Circuits Peking University Wuhan National High Magnetic Field Center and School of Integrated Circuits Huazhong University of Science and Technology

Two-dimensional （2D） transition metal dichalcogenide （TMDC） semiconductor materials exhibit extraordinary electrical properties,holding promise for the realization of next-generation complementary metal-oxide-semiconductor （CMOS） devices at ultimate ***,constrained by effective device doping strategies,the hole mobility and device performance of tungsten diselenide （WSe2） p-type transistors,especially monolayer chemical vapor deposition （CVD）-grown WSe2,have not met *** this paper,an effective performance enhancement of monolayer WSe2p-type transistor was achieved through a molecular doping *** monolayer WSe2directly on SiO2back-gated substrates and leveraging energy band alignment design,4-nitrobenzenediazonium tetrafluoroborate （4-NBD） molecular dopant with a concentration of 10 m M was utilized to modulate the Fermi level position of monolayer WSe2for hole *** devices demonstrated a more than 98%increase in hole mobility,reaching up to 97 cm2·V-1·s-1while maintaining the current on/off ratio of *** p-type WSe2transistors with 1μm channel length exhibit a high drive current surpassing 176μA·μm-1,exceeding previous CVD-WSe2devices with similar channel *** straightforward and effective approach to improving the electrical performance of WSe2transistors paves the way for advanced logic technologies based on transition metal dichalcogenide semiconductors.

关键词： CVD-grown WSe$_2$ molecular doping 4-NBD p-type transistors hole mobility

Effect of neutral polymeric bonding agent on tensile mechanical properties and damage evolution of NEPE propellant

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Defence Technology（防务技术） 2024年第2期32卷 357-367页

作者： M.Wubuliaisan yanqing Wu Xiao Hou Kun Yang Hongzheng Duan Xinmei Yin State Key Laboratory of Explosion Science and Technology Beijing Institute of TechnologyBeijing100081PR China The Fourth Institute of China Aerospace Science and Technology Corporation Xi'an710025PR China School of Aerospace Engineering Beijing Institute of TechnologyBeijing100081PR China Science and Technology on Aerospace Chemical Power Laboratory Hubei Institute of Aerospace ChemotechnologyHubei441003PR China

Introducing Neutral Polymeric bonding agents(NPBA) into the Nitrate Ester Plasticized Polyether(NEPE)propellant could improve the adhesion between filler/matrix interface, thereby contributing to the development of new generations of the NEPE propellant with better mechanical properties. Therefore,understanding the effects of NPBA on the deformation and damage evolution of the NEPE propellant is fundamental to material design and applications. This paper studies the uniaxial tensile and stress relaxation responses of the NEPE propellant with different amounts of NPBA. The damage evolution in terms of interface debonding is further investigated using a cohesive-zone model(CZM). Experimental results show that the initial modulus and strength of the NEPE propellant increase with the increasing amount of NPBA while the elongation decreases. Meanwhile, the relaxation rate slows down and a higher long-term equilibrium modulus is reached. Experimental and numerical analyses indicate that interface debonding and crack propagation along filler-matrix interface are the dominant damage mechanism for the samples with a low amount of NPBA, while damage localization and crack advancement through the matrix are predominant for the ones with a high amount of NPBA. Finally, crosslinking density tests and simulation results also show that the effect of the bonding agent is interfacial rather than due to the overall crosslinking density change of the binder.

关键词： Solid propellant Bonding agent Mechanical properties Damage evolution Cohesive-zone model Interface debonding

Metasurface-based computational imaging:a review

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Advanced Photonics 2024年第1期6卷 43-63页

作者： Xuemei Hu Weizhu Xu Qingbin Fan Tao Yue Feng Yan yanqing Lu Ting Xu Nanjing University Collaborative Innovation Center of Advanced MicrostructuresNational Laboratory of Solid-State MicrostructuresNanjingChina Nanjing University School of Electronic Sciences and EngineeringNanjingChina Nanjing University College of Engineering and Applied SciencesJiangsu Key Laboratory of Artificial Functional MaterialsNanjingChina

Metasurface-based imaging has attracted considerable attention owing to its compactness,multifunctionality,and subwavelength coding *** the integration of computational imaging techniques,researchers have actively explored the extended capabilities of metasurfaces,enabling a wide range of imaging *** present an overview of the recent progress in metasurface-based imaging techniques,focusing on the perspective of computational ***,we categorize and review existing metasurface-based imaging into three main groups,including(i)conventional metasurface design employing canonical methods,(ii)computation introduced independently in either the imaging process or postprocessing,and(iii)an end-to-end computation-optimized imaging system based upon *** highlight the advantages and challenges associated with each computational metasurface-based imaging technique and discuss the potential and future prospects of the computational boosted metaimager.

关键词： metasurface computational imaging inverse problem algorithm