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Embryo Transfer Strategies for Women with Recurrent Implantation Failure During the Frozen-thawed Embryo Transfer Cycles:Sequential Embryo Transfer or Double-blastocyst Transfer?

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Current Medical Science 2024年第1期44卷 212-222页

作者： Qiao-hang ZHAO Yu-wei SONG Jian CHEN Xiang ZHOU Ji-lai XIE Qiu-ping YAO Qi-yin DONG chun feng Li-ming ZHOU Wei-ping FU Min JIN The Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou 310052China Jiaxing Maternity and Child Health Care Hospital Jiaxing 314051China Huzhou Maternity and Child Care Hospital Huzhou 313002China Ningbo Women and Children's Hospital Ningbo 315000China

Objective Both sequential embryo transfer(SeET)and double-blastocyst transfer(DBT)can serve as embryo transfer strategies for women with recurrent implantation failure(RIF).This study aims to compare the effects of SeET and DBT on pregnancy *** Totally,261 frozen-thawed embryo transfer cycles of 243 RIF women were included in this multicenter retrospective *** to different embryo quality and transfer strategies,they were divided into four groups:group A,good-quality SeET(GQ-SeET,n=38 cycles);group B,poor-quality or mixed-quality SeET(PQ/MQ-SeET,n=31 cycles);group C,good-quality DBT(GQ-DBT,n=121 cycles);and group D,poor-quality or mixed-quality DBT(PQ/MQ-DBT,n=71 cycles).The main outcome,clinical pregnancy rate,was compared,and the generalized estimating equation(geE)model was used to correct potential confounders that might impact pregnancy *** GQ-DBT achieved a significantly higher clinical pregnancy rate(aOR 2.588,95%CI 1.267–5.284,P=0.009)and live birth rate(aOR 3.082,95%CI 1.482–6.412,P=0.003)than PQ/***,the clinical pregnancy rate was significantly higher in GQ-SeET than in PQ/MQ-SeET(aOR 4.047,95%CI 1.218–13.450,P=0.023).The pregnancy outcomes of GQ-SeET were not significantly different from those of GQ-DBT,and the same results were found between PQ/MQ-SeET and PQ/*** SeET relative to DBT did not seem to improve pregnancy outcomes for RIF patients if the embryo quality was comparable between the two *** clinical pregnancy outcomes could be obtained by transferring good-quality embryos,no matter whether in SeET or *** quality plays a more important role in pregnancy outcomes for RIF patients.

关键词： recurrent implantation failure sequential embryo transfer frozen-thawed embryo transfer embryo transfer strategies

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Glycine Attenuates Myocardial Fibrosis in Myocardial Infarction in Rats Partly through Modulating Signal Transducer and Activator of Transcription 3/Nuclear Factor-κB/Transforming Growth Factor-β axis

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World Journal of Traditional Chinese Medicine 2024年第2期10卷 263-270页

作者： Ning Li Yong Wang chun Li Xu Chen Xue-feng Zhang Nan Nan Tan Yi-Qin Hong Ming-Yan Shao Bing-Hua Tang Dong-Qing Guo School of Life Science Beijing University of Chinese MedicineBeijingChina College of Traditional Chinese Medicine Beijing University of Chinese MedicineBeijingChina Modern Research Center of Traditional Chinese Medicine School of Traditional Chinese Material MedicaBeijing University of Chinese MedicineBeijingChina

Objective: Inflammation and fibrosis are strongly associated with each other. Glycine is present in various traditional Chinese medicines and exhibits anti-inflammatory activity. However, the effects of glycine on myocardial fibrosis(MF) in rats with myocardial infarction(MI) have not been reported. The purpose of this study is to investigate the effects of glycine therapy on MF and comprehend its underlying mechanisms. Materials and Methods: Left anterior descending artery ligation-induced MI in Sprague Dawley rats was leveraged to assess the therapeutic effects of Glycine. Rats received either normal saline or glycine(0.5 mg/g bodyweight) for 7 days. Results: Glycine upregulated cardiac ejection fraction and fractional shortening to improve cardiac function, as evaluated by echocardiography. Histological and immunohistochemical analyses demonstrated that glycine could decrease inflammatory cell infiltration and alleviate collagen deposition. Western blotting revealed that nuclear factor-κB(NF-κB)-mediated inflammatory signaling was also downregulated by glycine treatment. The expression of signal transducer and activator of transcription 3(STAT3), tumor necrosis factor-α, and transforming growth factor-β(TGF-β) was decreased significantly in the glycine-treated group compared to the model group. Thus, glycine plays a protective role against myocardial ischemia and subsequent MF. Conclusion: The protective effects of glycine were achieved partly through STAT3/NF-κB/TGF-β signaling pathway.

关键词： Glycine myocardial fibrosis signal transducer and activator of transcription 3/nuclear factor-κB/transforming growth factor-β

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Layered oxide cathodes for sodium-ion batteries:microstructure design,local chemistry and structural unit

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Science China Chemistry 2024年第1期67卷 191-213页

作者： Ling-Yi Kong Han-Xiao Liu Yan-Fang Zhu Jia-Yang Li Yu Su Hong-Wei Li Hai-Yan Hu Yi-feng Liu Ming-Jing Yang Zhuang-chun Jian Xin-Bei Jia Shu-Lei Chou Yao Xiao Institute for Carbon Neutralization College of Chemistry and Materials EngineeringWenzhou UniversityWenzhou 325035China

Because of the low price and abundant reserves of sodium compared with lithium,the research of sodium-ion batteries(SIBs)in the field of large-scale energy storage has returned to the research *** oxides distinguish themselves from the mains cathode materials of SIBs owing to their advantages such as high specific capacity,simple synthesis route,and environmental ***,the commercial development of the layered oxides is limited by sluggish kinetics,complex phase transition and poor air *** on the research ideas from macro-to micro-scale,this review systematically summarizes the current optimization strategies of sodium-ion layered oxide cathodes(SLOC)from different dimensions:microstructure design,local chemistry regulation and structural unit *** the dimension of microstructure design,the various structures such as the microspheres,nanoplates,nanowires and exposed active facets are prepared to improve the slow kinetics and electrochemical ***,from the view of local chemistry regulation by chemical element substitution,the intrinsic electron/ion properties of SLOC have been enhanced to strengthen the structural ***,the optimization idea of endeavors to regulate the physical and chemical properties of cathode materials essentially is put forward from the dimension of structural unit *** opinions and strategies proposed in this review will provide some inspirations for the design of new SLOC in the future.

关键词： sodium-ion batteries layered oxide cathodes microstructure design local chemistry structural unit

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一种新颖的光纤色散测试方法

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光电子．激光 2005年第7期16卷 834-836页

作者：曾丽珠武星葛春风吕辰刚秦一帆倪玉婷天津大学精密仪器与光电子工程学院

在相移法的基础上,提出了一种新颖的基于普通单模光纤的色散测试方法,研制了相应的测试仪器。通过引入波长为1310nm的参考光,以波长间隔大的1310/1550nm波分复用/解复用(WDM)器代替了波长间隔小的WDM器,不仅减少了成本,且实验误差小于0.... 详细信息

在相移法的基础上,提出了一种新颖的基于普通单模光纤的色散测试方法,研制了相应的测试仪器。通过引入波长为1310nm的参考光,以波长间隔大的1310/1550nm波分复用/解复用(WDM)器代替了波长间隔小的WDM器,不仅减少了成本,且实验误差小于0.5ps。对研制过程中的主要问题进行说明。

关键词：色散相移法波分复用/解复用(WDM)

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Spleen volume is associated with overt hepatic encephalopathy after transjugular intrahepatic portosystemic shunt in patients with portal hypertension

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World Journal of Gastrointestinal Surgery 2024年第7期16卷 2054-2064页

作者： chun-Juan Zhao Chao Ren Zhen Yuan Guo-Hui Bai Jin-Yu Li Long Gao Jin-Hui Li Ze-Qi Duan Dui-Ping feng Hui Zhang College of Medical Imaging Shanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina Department of Radiology The First Hospital of Shanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina Department of Occupational Health School of Public HealthShanxi Key Laboratory of Environmental Health Impairment and PreventionNHC Key Laboratory of PneumoconiosisMOE Key Laboratory of Coal Environmental Pathogenicity and PreventionShanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina Department of Oncological and Vascular Intervention The First Hospital of Shanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina Shanxi Provincial Clinical Research Center for Interventional Medicine The First Hospital of Shanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina First Clinical Medical College Shanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina Shanxi Key Laboratory of Intelligent Imaging and Nanomedicine The First Hospital of Shanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina Intelligent Imaging Big Data and Functional Nano-imaging Engineering Research Center of Shanxi Province The First Hospital of Shanxi Medical UniversityTaiyuan 030001Shanxi ProvinceChina

BACKGROUND Portal shunt and immune status related to the spleen are related to the occurrence of hepatic encephalopathy(HE).It is unknown whether spleen volume before transjugular intrahepatic portosystemic shunt(TIPS)is related to postoperative *** To investigate the relationship between spleen volume and the occurrence of *** This study included 135 patients with liver cirrhosis who underwent TIPS,and liver and spleen volumes were elevated upon computed tomography *** Kaplan-Meier curve was used to compare the difference in the incidence rate of HE among patients with different spleen *** and multivariate Cox regression analyses were performed to identify the factors affecting overt HE(OHE).Restricted cubic spline was used to examine the shapes of the dose-response association between spleen volumes and OHE *** The results showed that 37(27.2%)of 135 patients experienced OHE during a 1-year follow-up *** with preoperative spleen volume(901.30±471.90 cm3),there was a significant decrease in spleen volume after TIPS(697.60±281.0 cm^(3))in OHE *** the severity of OHE increased,the spleen volume significantly decreased(P<0.05).Compared with patients with a spleen volume≥782.4 cm^(3),those with a spleen volume<782.4 cm^(3) had a higher incidence of HE(P<0.05).Cox regression analysis showed that spleen volume was an independent risk factor for post-TIPS OHE(hazard ratio=0.494,P<0.05).Restricted cubic spline model showed that with an increasing spleen volume,OHE risk showed an initial increase and then decrease(P<0.05).CONCLUSION Spleen volume is related to the occurrence of OHE after *** spleen volume is an independent risk factor for post-TIPS OHE.

关键词： Hepatic encephalopathy Transjugular intrahepatic portosystemic shunt Spleen volume Portal hypertension Cirrhosis

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多副本分布式事务处理关键技术及典型数据库系统综述

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软件学报 2024年第1期35卷 455-480页

作者：黄纯悦彭起张拂晓王声溢罗成张岩峰于戈东北大学计算机科学与工程学院辽宁沈阳110169

数据复制是分布式数据库提高可用性的重要手段,通过在不同区域放置数据库的部分副本,还可以提高本地读写操作的响应速度,增加副本数量也会提升读负载的线性扩展能力.考虑到这些优良特性,近年来国内外都出现了众多多副本分布式数据库系统... 详细信息

数据复制是分布式数据库提高可用性的重要手段,通过在不同区域放置数据库的部分副本,还可以提高本地读写操作的响应速度,增加副本数量也会提升读负载的线性扩展能力.考虑到这些优良特性,近年来国内外都出现了众多多副本分布式数据库系统,包括Google Spanner、CockroachDB、TiDB、OceanBase等一系列主流的工业界系统,也出现了包括Calvin、Aria、Berkeley Anna等一系列优秀的学术界系统.然而,多副本数据库带来诸多收益的同时,也带来了一致性维护、跨节点事务、事务隔离等一系列挑战.总结分析现有的复制架构、一致性维护策略、跨节点事务并发控制等技术,对比几个代表性多副本数据库系统之间在分布式事务处理方面上的差异与共同点,并在阿里云环境下搭建跨区域的分布式集群环境,对几个代表性系统的分布式事务处理能力进行了实验测试分析.

关键词：分布式事务处理分布式数据库数据复制确定性数据库跨区域复制数据库

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绿色草莓(Fragaria viridis Duch.)自交后代的性状观察及评价

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植物遗传资源学报 2014年第3期15卷 630-638页

作者：葛春峰张海元陈丙义蔡斌华乔玉山南京农业大学园艺学院南京210095

本研究对绿色草莓(Fragaria viridis Duch.)及其自交后代5个株系的植物学性状进行了观察,发现与亲本均存在一定程度差异,在观察的67个性状中,可溶性固形物等42个性状存在显著差异。利用SPSS软件对其中15个差异明显的性状进行主成分分析... 详细信息

本研究对绿色草莓(Fragaria viridis Duch.)及其自交后代5个株系的植物学性状进行了观察,发现与亲本均存在一定程度差异,在观察的67个性状中,可溶性固形物等42个性状存在显著差异。利用SPSS软件对其中15个差异明显的性状进行主成分分析和变异系数分析,结果表明植株高度、冠径、小花梗长、小花梗粗、花序梗粗及花粉生活力是区分绿色草莓及其自交后代株系的主要指标。5个自交一代株系自交坐果率差异明显,其中株系Ls-S1-4坐果率最低。本研究为绿色草莓自交亲和/不亲和系的创建奠定基础。

关键词：绿色草莓自交后代植物学性状主成分分析自交不亲和

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Simultaneous production of high-frequency synthetic apomixis with high fertility and improved agronomic traits in hybrid rice

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Molecular Plant 2024年第1期17卷 4-7页

作者： Mengqiu Song Wumei Wang chun Ji Shengnan Li Wei Liu Xiaoyu Hul Anhui feng Shuang Ruan Shiyun Du Huan Wang Kui Dai Longbiao Guo Qian Qian Hongqi Si Xingming Hu College of Agronomy Anhui Agricultural UniversityHefeiAnhui 230036China State Key Laboratory of Rice Biology China National Rice Research InstituteHangzhouZhejiang 310006China Rice Research Institute Anhui Academy of Agricultural SciencesHefeiAnhui 230031China Jiangxi Modern Seed Industry Co.NanchangJiangxi 330026China

Dear Editor,Utilization of heterosis is fundamental to modern agricultural improvement and contributes significantly to food security and agricultural development(Ouyang et al.,2022).However,heterosis of F,hybrids cannot be stably ***,or asexual reproduction through seeds,offers the potential for the fixation of heterosis in F,hybrids and the formation of clonal offspring,which could have considerable implications for plant breeding and agriculture(Schmidt,2020).But naturally occurring apomixis has never been found in major ***,synthetic apomixis has been successfully generated by inducing incomplete meiotic development combined with parthenogenesis development to produce cloned rice(Oryza sativa)seeds(Khanday et al.,2019;Wang et al.,2019;Vernet et al.,2022;Wei et al.,2023).

关键词： sativa fertility breeding

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通智测试——基于动态具身物理社会交互环境的通用人工智能测试

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Engineering 2024年第3期34卷 12-22页

作者： Yujia Peng Jiaheng Han Zhenliang Zhang Lifeng Fan Tengyu Liu Siyuan Qi Xue feng Yuxi Ma Yizhou Wang Song-chun Zhu National Key Laboratory of general Artificial Intelligence Beijing Institute for General Artificial IntelligenceBeijing 100086China Institute for Artificial Intelligence Peking UniversityBeijing 100871China Beijing Key Laboratory of Behavior and Mental Health School of Psychological and Cognitive SciencesPeking UniversityBeijing 100871China School of Intelligence Science and Technology Peking UniversityBeijing 100871China School of Computer Science Peking UniversityBeijing 100871China

The release of the generative pre-trained transformer(GPT)series has brought artificial general intelligence(AGI)to the forefront of the artificial intelligence(AI)field once ***,the questions of how to define and evaluate AGI remain *** perspective article proposes that the evaluation of AGI should be rooted in dynamic embodied physical and social interactions(DEPSI).More specifically,we propose five critical characteristics to be considered as AGI benchmarks and suggest the Tong test as an AGI evaluation *** Tong test describes a value-and ability-oriented testing system that delineates five levels of AGI milestones through a virtual environment with DEPSI,allowing for infinite task *** contrast the Tong test with classical AI testing systems in terms of various aspects and propose a systematic evaluation system to promote standardized,quantitative,and objective benchmarks and evaluation of AGI.

关键词： Artificial general intelligence Artificial intelligence benchmark Artificial intelligence evaluation Embodied artificial intelligence Value alignment Turing test Causality

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熔锥型全波耦合器

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物理学报 2003年第2期52卷 390-394页

作者：张瑞峰葛春风王书慧胡智勇李世忱天津大学精密仪器与光电子工程学院光电科学技术教育部重点实验室天津300072

从耦合模方程出发 ,分析了全光纤非对称熔融拉锥型耦合器的带宽特性 ,提出和论证了全波 (O +E +S +C +Lband)耦合器的制作方案 ,并且在工艺上实现了全波耦合 ,其带宽达到了 390nm(12 6 0— 16 5 0 ) ,分束比 1∶99;附加损耗0 1dB .

关键词：全波耦合器熔融拉锥带宽预拉伸光纤通信

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