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Ti-B19钛合金的β→α+β等温相变动力学

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稀有金属材料与工程 2006年第11期35卷 1695-1699页

作者：常辉 e.gautier F.Bruneseaux 周廉西北工业大学 LSG2M Ecloe des Mines de Nancy Parc de Saurupt 54042 Nancy Cedex France

利用原位电阻法、同步X射线衍射等技术较为系统地研究了亚稳β钛合金Ti-B19的β→α+β等温相变动力学。结果表明,在试验温度范围内,Ti-B19合金的等温相变为长程扩散控制的形核与长大过程,可以用JMA方程进行描述。在试验温度范围,500℃... 详细信息

利用原位电阻法、同步X射线衍射等技术较为系统地研究了亚稳β钛合金Ti-B19的β→α+β等温相变动力学。结果表明,在试验温度范围内,Ti-B19合金的等温相变为长程扩散控制的形核与长大过程,可以用JMA方程进行描述。在试验温度范围,500℃等温时效时相转变完成所需时间最短,相转变速度最快,当温度大于500℃时,随温度升高,相转变速度降低,这与相转变驱动力不足有关。当温度低于500℃时,由于受溶质扩散速度的影响,完成相转变所需时间更长。α相的数量是温度的函数,在500℃等温时,α相的数量最多,为57.7%,然后随温度的升高,α相的数量减少。根据试验结果,绘制了合金的时间-温度-转变量图(TTT图),其“鼻温”在500℃～550℃之间。

关键词：钛合金等温相变动力学

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外加应力对贝氏体相变组织形貌的影响

材料科学与工艺 2005年第3期13卷 251-253页

作者：苏铁健李树奎张朝晖 AeBY-gautier e DeNIS S BRIeN V 北京理工大学材料科学与工程学院 ecole des Mines de Nancy Parc de Saurupt Nancy 54042 China

为揭示贝氏体相变机制及外加应力对它的影响,采用透射电镜研究了140MPa的外加拉应力对中碳低合金钢35MV7的450°C等温贝氏体相变组织形貌的影响.研究发现,由于外加应力的存在,贝氏体相变基元及其组成的铁素体条的尺寸变得非常粗大并形... 详细信息

为揭示贝氏体相变机制及外加应力对它的影响,采用透射电镜研究了140MPa的外加拉应力对中碳低合金钢35MV7的450°C等温贝氏体相变组织形貌的影响.研究发现,由于外加应力的存在,贝氏体相变基元及其组成的铁素体条的尺寸变得非常粗大并形成多样的变态.这种尺寸的变化是由于外加应力产生额外的相变驱动力,使相变基元块可以克服更大的弹性应变能而长成更大的体积.

关键词：贝氏体相变外加应力组织形貌中碳低合金钢透射电镜研究相变基元相变驱动力弹性应变能相变机制应力产生拉应力铁素体尺寸

Nanorocks, volatiles and plate tectonics

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Geoscience Frontiers 2021年第5期12卷 202-214页

作者： gautier Nicoli Silvio Ferrero Institut für Geowissenschaften Universität Potsdam14476 Potsdam-GolmGermany Museum für Naturkunde(MfN) Leibniz-Institut für Evolutions-und Biodiversitätsforschung10115 BerlinGermany

The global geological volatile cycle(H,C,N)plays an important role in the long term self-regulation of the earth ***,the complex interaction between its deep,solid earth components(*** and mantle),earth’s fluid envelopes(*** and hydrosphere)and plate tectonic processes is a subject of ongoing *** this study we want to draw attention to how the presence of primary melt(MI)and fluid(FI)inclusions in high-grade metamorphic minerals could help constrain the crustal component of the volatile *** that end,we review the distribution of MI and FI throughout earth’s history,from ca.3.0 Ga ago up to the present *** argue that the lower crust might constitute an important,longterm,volatile storage unit,capable to influence the composition of the surface envelopes through the mean of weathering,crustal thickening,partial melting and crustal assimilation during volcanic *** with thermodynamic modelling,our compilation indicates that periods of well-established plate tectonic regimes ate more prone to the reworking of supracrustal lithologies and the storage of volatiles in the lower *** hypothesis has implication beyond the scope of metamorphic petrology as it potentially links geodynamic mechanisms to habitable surface *** and FI in metamorphic crustal rocks then represent an invaluable archive to assess and quantify the co-joint evolution of plate tectonics and earth’s external processes.

关键词： Nanorocks Plate tectonics Volatiles Lower crust

Hepatitis B Surface Antigen and Hepatitis C Virus Antibodies among Drug Users in Burkina Faso

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Advances in Microbiology 2024年第1期14卷 92-104页

作者： Sylvie Zida Kadari Cissé Odette Ky-Zerbo Dinanibè Kambiré Serge Théophile Soubeiga Simon Tiendrebéogo Fatou Sissoko Issa Sory Célestine Ki-Toé Solange Dioma Djeneba Zorom Adama Ouédraogo Cedric Dimitri Axon Hien Mahamoudou Sanou Seni Kouanda Henri gautier Ouédraogo Institut de Recherche en Sciences de la Sant&eacute Ouagadougou Burkina Faso D&eacute partement de G&eacuteographie Universit&eacute Norbert ZONGO Koudougou Burkina Faso Secr&eacute tariat permanent du Conseil national de lutte contre le Sida et les IST (SP/CNLS-IST) Ouagadougou Burkina Faso Initiative Priv&eacute e et Communautaire pour la Sant&eacute et la Riposte au VIH/SIDA au Burkina Faso (IPC/BF) Ouagadougou Burkina Faso Unit&eacute de Formation et de Recherche en Sciences de la Sant&eacute (UFR-SDS) Universit&eacute Joseph KI-ZERBO Ouagadougou Burkina Faso

Introduction: The epidemiology of both hepatitis B virus (HBV) and hepatitis C virus (HCV) infections among drug users (DUs) is little known in West Africa. The study aimed to assess the prevalence of hepatitis B and C viruses among drug users in Burkina Faso. Methodology: This was a cross-sectional biological and behavioral survey conducted between June and August 2022, among drug users in Ouagadougou and Bobo Dioulasso, the two main cities of Burkina Faso. A respondent-driven sampling (RDS) was used to recruit drug users. Hepatitis B surface antigen was determined using lateral flow rapid test kits and antibodies to hepatitis C virus in serum determined using an enzyme-Linked Immunosorbent Assay. Data were entered and analyzed using Stata 17 software. Weighted binary logistic regression was used to identify the associated factors of hepatitis B and C infections and a p-value Results: A total of 323 drug users were recruited with 97.5% males. The mean age was 32.7 years old. The inhaled or smoked mode was the most used by drug users. The adjusted hepatitis B and hepatitis C prevalence among study participants were 11.1% and 2.3% respectively. The marital status (p = 0.001), and the nationality (p = 0.011) were significantly associated with hepatitis B infection. The type of drug used was not significantly associated with hepatitis B infection or hepatitis C infection. Conclusion: The prevalence of HBsAg and anti-HCV antibodies among DUs are comparable to those reported in the general population in Burkina Faso. This result suggests that the main routes of contamination by HBV and HCV among DUs are similar to those in the population, and could be explained by the low use of the injectable route by DUs in Burkina Faso.

关键词： Drug Users Hepatitis C Hepatitis B Prevalence Burkina Faso

Refinement of Bouguer anomalies derived from the eGM2008 model,impact on gravimetric signatures in mountainous region:Case of Cameroon Volcanic Line,Central Africa

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earth and Planetary Physics 2020年第6期4卷 639-650页

作者： Paul gautier Kamto Cyrille Mezoue Adiang Severin Nguiya Joseph Kamguia Loudi Yap Geodesy Research Laboratory National Institute of Cartography(NIC)YaoundeCameroon Department of Physics Faculty of ScienceUniversity of Yaounde ICameroon Laboratory e3M Faculty of Industrial EngineeringUniversity of DoualaCameroon Department of Physics Faculty of ScienceUniversity of DoualaCameroon

Global geopotential models have not included the very high frequencies of the earth’s external gravity *** is called omission *** omission error becomes more important in mountainous areas(areas with highly variable topography).The work reported here consists in reducing the omission error in measurements of Bouguer gravity anomalies,by refining the global geopotential model eGM2008 using the spectral enhancement *** method consists in computing the residual terrain effects and then coupling them to the gravimetric signal of the global geopotential *** compute the residual terrain effects,we used the Residual Terrain Model(RTM)*** refine it required a reference surface(eTOPO1)developed up to degree 2190(the maximum degree of the eGM2008 model)and a detailed elevation model(AW3D30).Computation was performed with the TC program of the GRAVSOFT *** topography of the study area was assumed to have a constant density of 2670 kg/*** the inner and outer zones,the respective integration radii of 10 km and 200 km have been *** obtained very important RTM values ranging from−53.59 to 34.79 *** values were added to the gravity anomalies grid of the eGM2008 model to improve accuracy at high *** a part of the Cameroon Volcanic Line and its surroundings(mountainous area),we made a comparison between the residual Bouguer anomalies before and after *** report differences ranging from−37.40 to 26.40 *** conclude that the impact of omission error on gravimetric signatures is observed especially in areas with high variable topography,such as on the Cameroon Volcanic Line and around the localities of Takamanda,essu,Dumbo,and *** finding illustrates the great influence that topography has on accurate measurement of these gravity anomalies,and thus why topography must be taken into *** can conclude that in preparing a global geopotential model,a high resolution DTM must be used to decrease

关键词： residual Terrain Model eGM2008 Omission error refined Bouguer anomalies mountainous area

基于流线理论计算正交切削中应变率和应变的方法

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东北大学学报（自然科学版） 2009年第8期30卷 1185-1188页

作者：毕雪峰刘永贤 gautier LIST 刘阳东北大学机械工程与自动化学院辽宁沈阳110004 LPMM Université de Metz metz57045

依据流体力学中的流线理论,选用了一个较为通用的流线模型,对正交金属切削时的塑性变形进行了分析研究.对实验获得的切削中的流线轨迹和流线模型进行拟合,确定了模型中的几何参数.应用流线理论和塑性理论相结合的方法,计算了剪切区的应... 详细信息

依据流体力学中的流线理论,选用了一个较为通用的流线模型,对正交金属切削时的塑性变形进行了分析研究.对实验获得的切削中的流线轨迹和流线模型进行拟合,确定了模型中的几何参数.应用流线理论和塑性理论相结合的方法,计算了剪切区的应变率分布,其结果与前人的实验和计算结果基本吻合,说明此流线模型可以用来分析金属切削中的塑性变形.对应变率进行数值积分,得到了剪切区的应变分布.根据计算的应变结果,提出了一种定义剪切区形状的方法.

关键词：正交切削塑性变形流线模型应变剪切区形状

Nonlinear ionization dynamics of hot dense plasma observed in a laser-plasma amplifier

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Light(Science & Applications) 2020年第1期9卷 196-203页

作者： F.Tuitje P.Martinez Gil T.Helk J.gautier F.Tissandier J.-P.Goddet A.Guggenmos U.Kleineberg S.Sebban e.Oliva C.Spielmann M.Zurch Institute for Optics and Quantum electronics Abbe Center of PhotonicsUniversity of JenaJenaGermany Helmholtz Institute Jena JenaGermany Departamento de Ingenieria energetica and Instituto de Fusion Nuclear“Guillermo Velarde” ETSI IndustrialesUniversidad Politecnica de MadridMadridSpain Laboratoire d’Optique Appliquee ENSTA ParisEcole PolytechniqueCNRSInstitut Polytechnique de ParisPalaiseauFrance Department for Physics Ludwig-Maximilian-University MunichGarchingGermany Ultra Fast Innovations GmbH GarchingGermany Fritz Haber Institute of the Max Planck Society BerlinGermany Department of Chemistry University of California at BerkeleyBerkeleyCAUSA Materials Sciences Division Lawrence Berkeley National LaboratoryBerkeleyCAUSA

Understanding the behaviour of matter under conditions of extreme temperature,pressure,density and electromagnetic fields has profound effects on our understanding of cosmologic objects and the formation of the *** direct access to such objects,our interpretation of observed data mainly relies on theoretical ***,such models,which need to encompass nuclear physics,atomic physics and plasma physics over a huge dynamic range in the dimensions of energy and time,can only provide reliable information if we can benchmark them to experiments under well-defined laboratory *** to the plethora of effects occurring in this kind of highly excited matter,characterizing isolated dynamics or obtaining direct insight remains ***-density plasmas are turbulent and opaque for radiation below the plasma frequency and allow only near-surface insight into ionization processes with visible ***,the output of a high-harmonic seeded laser-plasma amplifier using eightfold ionized krypton as the gain medium operating at a 32.8 nm wavelength is ptychographically imaged.A complexvalued wavefront is observed in the extreme ultraviolet(XUV)beam with high *** initio spatio-temporal Maxwell–Bloch simulations show excellent agreement with the experimental observations,revealing overionization of krypton in the plasma channel due to nonlinear laser-plasma interactions,successfully validating this four-dimensional multiscale *** constitutes the first experimental observation of the laser ion abundance reshaping a laserplasma *** presented approach shows the possibility of directly modelling light-plasma interactions in extreme conditions,such as those present during the early times of the universe,with direct experimental verification.

关键词： extreme ionization dynamics

Multiparametric characterization of red blood cell physiology after hypotonic dialysis based drug encapsulation process

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Acta Pharmaceutica Sinica B 2022年第4期12卷 2089-2102页

作者： Mélanie Robert Bastien Laperrousaz Diana Piedrahita emilie-Fleur gautier Travis Nemkov Florian Dupuy elie Nader Virginie Salnot Patrick Mayeux Angelo D’Alessandro Catherine Lavazec Philippe Joly Alexander Scheer Philippe Connes Agnès Cibiel erytech Pharma Lyon 69008France Laboratoire interuniversitaire de Biologie de la Motricité(LIBM)eA7424 Team«Vascular Biology and Red Blood Cell»Universite´Claude Bernard Lyon 1Universite´de LyonLyon 69008France Labex GR-ex Paris 75015France 3P5 proteom’IC facility Universitéde ParisInstitut CochinINSERMCNRSParis 75014France University of Colorado Anschutz Medical CampusAuroraCO 80045USA Omix Technologies Inc.AuroraCO 80045USA Inserm U1016 CNRS 8104Universitéde ParisInstitut CochinParis 75014France Laboratoire de Biochimie et de Biologie Moléculaire UF de biochimie des pathologies e´rythrocytairesCentre de Biologie et de Pathologie EstHospices Civils de LyonBron 69500France

Red blood cells(RBCs)can act as carriers for therapeutic agents and can substantially improve the safety,pharmacokinetics,and pharmacodynamics of many *** RBCs integrity and lifespan is important for the efficacy of RBCs as drug *** investigated the impact of drug encapsulation by hypotonic dialysis on RBCs physiology and *** parameters were compared between processed RBCs loaded with l-asparaginase(“eryaspase”),processed RBCs without drug and non-processed *** RBCs were less hydrated and displayed a reduction of intracellular *** observed a change in the metabolomic but not in the proteomic profile of processed *** process caused moderate morphological changes and was accompanied by an increase of RBCs-derived extracellular Vesicles *** a decrease in deformability,processed RBCs were not mechanically retained in a spleen-mimicking device and had increased surface-to-volume ratio and osmotic *** RBCs half-life was not significantly affected in a mouse model and our previous phase 1 clinical study showed that encapsulation of asparaginase in RBCs prolonged its in vivo half-life compared to free *** study demonstrated that encapsulation by hypotonic dialysis may affect certain characteristics of RBCs but does not significantly affect the in vivo longevity of RBCs or their drug carrier function.

关键词： Red blood cells Drug carrier Hypotonic dialysis L-Asparaginase Omics Rheology Morphology Senescence markers

Spatial and Temporal Stability of Major and Trace element Leaching in Urban Stormwater Sediments

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Open Journal of Soil Science 2017年第11期7卷 347-365页

作者： Clémentine Drapeau Cécile Delolme Vincent Chatain Mathieu gautier Denise Blanc Mostafa Benzaazoua Laurent Lassabatère Université de Lyon ENTPE LEHNA (Laboratoire d’Ecologie des Hydro-systèmes Naturels et Anthropisés) Vaulx-en-Velin France Université de Lyon INSA Lyon DEEP (Déchets Eaux Environnement Pollutions Villeurbanne France Université du Québec en Abitibi-Témiscamingue Rouyn-Noranda Québec Canada

Urban sediment generated by stormwater management techniques are highly contaminated with various trace elements. The characterization of trace element speciation and mobility are critical information to improve environmental risk assessment. This study investigates the spatial and temporal variability of major and trace element release from a sedimentary layer in Django Reinhart stormwater infiltration basin (Chassieu, eastern suburbs of Lyon, France). Sampling was conducted for 3 zones and two dates. Chemical characterization was performed (X-Ray diffraction, ICP-AeS). The samples were submitted to Acid Neutralization Capacity & Base Neutralization Capacity ANC-BNC tests, according to european standard 14429 (AFNOR, 2015). Solid matrices were mixed with acid or basic solutions and physicochemical parameters and major and trace element release (i.e. Al, Ca, Fe, P, S, Si, Cu, Zn and total carbon) were followed as a function of pH. The results show that the urban sediment has no significant spatial and temporal variability with regards to element release. This observation is all the more surprising that the samples were collected in three contrasting zones regarding stormwater supply and hydric conditions. element release follows the same trends as a function of pH with a bell-shaped solubilization curve exhibiting with the highest solubility at extreme pH values. However, the samples showed slight differences concerning the release of major elements. Such differences are related to slight differences in total mineral contents (organic matter, carbonates…) and chemical composition of the sediments. The results show that despite the varying environmental conditions, the sediment chemical properties can be considered as very stable and uniform over space, depending mainly on the local geochemical context and watershed characteristics. This study highlights the strength and affluence of the information obtained by ANC-BNC tests on the release of major and traces metal e

关键词： Component Urban Sediment element Release Acid and Basic Neutralization Capacity