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CSELM-QE: A Composite Semi-supervised Extreme Learning Machine with Unlabeled RSS Quality Estimation for Radio Map Construction

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Chinese Journal of Electronics 2020年第6期29卷 1016-1024页

作者： ZHAO Jianli WANG Wei SUN Qiuxia HUO Huan SUN Guoqiang gao xiang ZHU Chendi College of Computer Science and Engineering Shandong University of Science and Technology College of Mathematics and Systems Science Shandong University of Science and Technology Faculty of Engineering and Information Technology University of Technology Sydney

Wireless local area network(WLAN)fingerprint-based localization has become the most attractive and popular approach for indoor ***,the primary concern for its practical implementation is the laborious manual effort of calibrating sufficient location-labeled *** Semi-supervised extreme learning machine(SELM) performs well in reducing calibration *** SELM methods only use Received signal strength(RSS) information to construct the neighbor graph and ignores location information,which helps recognizing prior information for manifold *** propose Composite SELM(CSELM) method by using both RSS signals and location information to construct composite ***,the issue of unlabeled RSS data quality has not been *** propose a novel approach called Composite semisupervised extreme learning machine with unlabeled RSS Quality estimation(CSELM-QE) that takes into account the quality of unlabeled RSS data and combines the composite neighbor graph,which considers location information in the semi-supervised extreme learning *** results show that the CSELM-QE could construct a precise localization model,reduce the calibration effort for radio map construction and improve localization *** quality estimation method can be applied to other methods that need to retain high quality unlabeled Received signal strength data to improve model accuracy.

关键词： localization accuracy location-labeled fingerprints calibration effort wireless local area network fingerprint-based localization indoor localization signal strength data Radio links and equipment Combinatorial mathematics calibration Composite Semisupervised extreme learning machine Radionavigation and direction finding unlabeled RSS data quality traditional SELM methods RSS signals precise localization model graph theory Composite SELM method location information radio map construction composite graph received signal strength information composite neighbor graph CSELM-QE wireless LAN indoor radio RSSI learning (artificial intelligence) quality estimation method unlabeled RSS Quality estimation

Suppressing thermal quenching via defect passivation for efficient quasi-2D perovskite light-emitting diodes

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Light(Science & Applications) 2022年第4期11卷 644-653页

作者： Dezhong Zhang Yunxing Fu Hongmei Zhan Chenyang Zhao xiang gao Chuanjiang Qin Lixiang Wang State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei 230026China

Emission thermal quenching is commonly observed in quasi-2D perovskite emitters,which causes the severe drop in luminescence eficiency for the quasi-2D perovskite light-emitting diodes(Pel EDs)during practical ***,this issue is often neglected and rarely studied,and the root cause of the thermal quenching has not been completely revealed ***,we develop a passivation strategy via the 2,7-dibromo-9,9-bis(3'-diethoxylphosphorylpropyl-fluorene to investigate and suppress the thermal *** agent can effectively passivate coordination-unsaturated Pb2+defects of both surface and bulk of the flm without affecting the perovskite crysaliation,which helps to more truly demonstrate the important role of defects in thermal *** our results reveal the root cause that the quenching will be strengthened by the defect promoted exciton-phonon ***,the PeL EDs with defect passivation achieve an improved external quantum efficiengy(EQE)over 22%and doubled operation lifetime at room temperature,and can maintain about 85%of the initial EQE at 85℃,much higher than 17%of the control *** findings provide an important basis for fabricating practical PeLEDs for lighting and displays.

关键词： thermal defect quenching

Personalized pancreatic cancer therapy:from the perspective of mRNA vaccine

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Military Medical Research 2023年第4期10卷 461-477页

作者： Xing Huang Gang Zhang Tian‑Yu Tang xiang gao Ting‑Bo Liang Zhejiang Provincial Key Laboratory of Pancreatic Disease the First Affiliated HospitalZhejiang University School of MedicineHangzhou 310009China Department of Hepatobiliary and Pancreatic Surgery the First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Zhejiang Clinical Research Center of Hepatobiliary and Pancreatic Diseases Hangzhou 310003China The Innovation Center for the Study of Pancreatic Diseases of Zhejiang Province Hangzhou 310009China Cancer Center Zhejiang UniversityHangzhou 310058China

Pancreatic cancer is characterized by inter-tumoral and intra-tumoral heterogeneity,especially in genetic alteration and *** therapeutic strategies for pancreatic cancer usually suffer resistance,highlighting the necessity for personalized precise *** vaccines have become promising alternatives for pancreatic cancer treatment because of their multifaceted advantages including multiple targeting,minimal nonspecific effects,broad therapeutic window,low toxicity,and induction of persistent immunological *** conventional vaccines based on the cells,microorganisms,exosomes,proteins,peptides,or DNA against pancreatic cancer have been developed;however,their overall efficacy remains *** with these vaccine modalities,messager RNA(mRNA)-based vaccines offer technical and conceptional advances in personalized precise treatment,and thus represent a potentially cutting-edge option in novel therapeutic approaches for pancreatic *** review summarizes the current progress on pancreatic cancer vaccines,highlights the superiority of mRNA vaccines over other conventional vaccines,and proposes the viable tactic for designing and applying personalized mRNA vaccines for the precise treatment of pancreatic cancer.

关键词： Pancreatic cancer Precise therapy Cancer vaccine mRNA vaccine Tumor antigen Immune subtype

Copper carbonate nanoparticles as an effective biomineralized carrier to load macromolecular drugs for multimodal therapy

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Chinese Chemical Letters 2023年第9期34卷 204-209页

作者： Liping Dong Jinsong Ding Lemei Zhu Yujun Liu xiang gao Wenhu Zhou Changsha Medical University Academician WorkstationChangsha 410219China xiangya School of Pharmaceutical Sciences Central South UniversityChangsha 410013China State Key Laboratory of Toxicology and Medical Countermeasures Institute of Pharmacology and ToxicologyBeijing 100850China Key Laboratory of Biological Nanotechnology of National Health Commission Changsha 410000China

Macromolecular drugs have attracted great interest as biotherapy to cure previously untreatable *** clinical translation,biomacromolecules encounter several common druggability difficulties,such as in vivo instability and poor penetration to cross physiologic barriers,thus requiring sophisticated systems for drug *** by the natural biomineralization via interaction between inorganic ions and biomacromolecules,herein we rationally screened biocompatible transition metals to biomineralize with carbonate for macromolecules *** the metal ions,Cu^(2+)was found to be the best candidate,and its superiority over the widely studied Ca^(2+)minerals was also *** on this finding,copper carbonate nanoparticles were prepared via a simple mixing process to co-load glucose oxidase(GOx)and a HIF-αDNAzyme(DZ),achieving ultra-high loading capacity of 61%.Upon encapsulation into nanoparticles,enzymatic activity of both drugs was passivated to avoid potential side-effects during circulation,while the drugs could be rapidly released within 1 h in response to acidic p H to fully recover their *** nanoparticles could accumulate into tumor via intravenous injection,facilitate the cell membrane penetration,and release the payloads of GOx,DZ and Cu^(2+)inside cells to exert a series of anti-tumor *** caused tumor starvation by catalytic glucose consumption,and the concomitantly generated H_(2)O_(2)byproduct boosted the Cu^(2+)-mediated chemodynamic therapy(CDT).Meanwhile,the DZ silenced HIF-αexpression to sensitize both starvation therapy and *** a result,a synergistic tumor growth inhibition was *** work provides a simple method to prepare biomineralized nanoparticles,and offers a general approach for macromolecular drugs delivery via Cu^(2+)-based biomineralization.

关键词： Metal ions Biomineralization Drug delivery Nanomedicine Tumor therapy

Effect of Sample Thickness on Magneto-Optic Imaging for Vortex Fully Penetrated Square-Shaped Superconductors

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Chinese Physics Letters 1998年第1期15卷 65-67页

作者： LIU Yun gao Zheng-xiang TAO Jing HAN Ru-shan Department of Physics Peking UniversityBeijing 100871

A significant effect of sample thickness on three components of the magnetic flux density distribution on square-shaped superconductor surface is shown,and the critical current density jc of the superconductor from th... 详细信息

关键词： superconductor Vortex Superconductor

Monitoring and early warning system of porcine pasteurellosis based on WebGIS

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Information Processing in Agriculture 2021年第1期8卷 148-158页

作者： Zihan Zhu Haoran Wang Li gao xiang gao Xinghua Meng Yao Xu Jianhua Xiao Department of Veterinary Surgery Northeast Agricultural UniversityHarbin 150030China

The incidence of porcine pasteurellosis in China is so widespread that it is difficult to clearly understand the prevalence and maintain continuous *** order to reduce immense negative economic impact on the livestock industry;monitoring,early warning,and visual management systems are highly *** this study,a monitoring and early warning systemfor porcine pasteurellosis was established based onWeb Geographical Information System(WebGIS)*** establishing a path analysis function,buffer analysis function,and hot spot analysis function,it can provide a method of support and control of infectious *** early warning of disease,four common interpolation methods were tested,all of which showed that the affected area of porcine pasteurellosis in China was mainly concentrated in the south of the mainland.A cross-validation method was used to compare the four interpolation *** cross-validation showed that the inverse distance weighting(IDW)method was suitable for forecasting the occurrence of porcine pasteurellosis in ***,using C sharp(C#)as the development language and WebGIS technology,a monitoring and early warning system based on Browser/Server structure was *** is the first monitoring and early warning system of porcine pasteurellosis based *** performance of theWebGIS technology indicated a great potential for animal infectious disease applications and provided a foundation for future work.

关键词： Porcine pasteurellosis Monitoring and early warning Web geographical information system Inverse distance weighting

The Performance Evolution Characteristics of Insitu Concrete at the Permafrost Regions

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Journal of Wuhan University of Technology(Materials Science) 2024年第6期39卷 1534-1540页

作者： NING Zuojun LI Haoxin NIE Kangjun Nueraili Maimaitituersun Aihemaitijiang Tuerhong gao xiang School of Transportation Kashi UniversityKashi 844000China KeyLaboratory of Advanced Civil Engineering Materials of Ministry of Education School of Materials Science and EngineeringTongji UniversityShanghai 201804China

This study aimed to investigate the performance evolution characteristics of concrete under permafrost ambient temperatures and to explore methods to mitigate the thermal perturbation by concrete on the permafrost environment.A program was designed to investigate the properties of various concretes at three curing *** compressive strength development pattern of each group was evaluated and the concrete's performance was characterized by compressive strength damage degree,hydration temperature and SEM analysis in a low temperature *** experimental results show that the incorporation of fly ash alone or incombination with other admixtures in concrete under low-temperature curing does not deteriorate its microstructure,and at the same time,it can slow down the hydration rate of cement and significantly reduce the exothermic heat of hydration of *** findings are expected to provide valuable references for the proportioning design of concrete in permafrost environments.

关键词： permafrost ambient mineral admixture compressive strength hydration temperature damage degree

DECLARATIVE HYBRID ROUTING PROTOCOLS IN AD HOC NETWORKS

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Journal of Electronics(China) 2013年第4期30卷 341-351页

作者： gao xiang Li Zhongyuan Wang Min School of Computer Science Northwestern Polytechnical University School of Communication Air Force Engineering University

This paper presents adaptive hybrid protocols based on the declarative network and mainly discusses the principle and realization of the Bayesian-estimation based adaptive hybrid protocol in the declarative network, which is well adapted to the Mobile Ad hoc NETwork (MANET). The adaptive hybrid protocol is designed for ad hoc networks which have characteristics like self-organizing, no trusted party, flexibility, etc. The nodes that run the hybrid protocol can automatically select one routing protocol that is suitable for different network environment. The Bayesian-estimation based adaptive strategy, that improves the adaptability and stability of the protocol, succeeds in the Rapidnet, a declarative network engine. The result in the Rapidnet proves that the hybrid protocol and the adaptive strategy are feasible. The experiment on the ns-3 simulator, an emerging discrete-event network simulator, validates that this protocol performs well and reduces communication overheads.

关键词： Declarative network Bayesian estimation Hybrid routing protocol Adaptive strategy Mobile Ad hoc NETwork (MANET)

Transfer-free chemical vapor deposition graphene for nitride epitaxy: challenges, current status and future outlook

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Science China Chemistry 2024年第3期67卷 824-840页

作者： xiang gao Senlin Li Jingfeng Bi Kaixuan Zhou Meng Li Zhongfan Liu Jingyu Sun College of Energy Soochow Institute for Energy and Materials InnovationsSUDA-BGI Collaborative Innovation CenterKey Laboratory of Advanced Carbon Materials and Wearable Energy Technologies of Jiangsu ProvinceSoochow UniversitySuzhou 215006China Beijing Graphene Institute Beijing 100095China Xiamen Silan Advanced Compound Semiconductor Co.Ltd. Xiamen 361026China

Graphene, a two-dimensional material with outstanding electrical and mechanical properties, has attracted considerable attention in the field of semiconductor technologies due to its potential use as a buffer layer for the epitaxial Ⅲ-nitride growth. In recent years, significant progress has been made in the chemical vapor deposition growth of graphene on various insulating substrates for the nitride epitaxy, which offers a facile, inexpensive, and easily scalable methodology. However, certain challenges are still present in the form of producing high-quality graphene and achieving optimal interface compatibility with Ⅲ-nitride *** this review, we provide an overview of the bottlenecks associated with the transferred graphene fabrication techniques and the state-of-the-art techniques for the transfer-free graphene growth. The present contribution highlights the current progress in the transfer-free graphene growth on different insulating substrates, including sapphire, quartz, SiO_(2)/Si, and discusses the potential applications of transfer-free graphene in the Ⅲ-nitride epitaxy. Finally, it includes the prospects of the transfer-free graphene growth for the Ⅲ-nitride epitaxy and the challenges that should be overcome to realize its full potential in this field.

关键词： Transfer-free chemical vapor deposition graphene for nitride epitaxy challenges current status and future outlook graphene